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Tag Content
iUUCD ID IUUC-Mor-056962
Ensembl Protein ID MGG_09369T0
UniProt Accession A4R3M4; G4NI24; LIS1_MAGO7
Genbank Protein ID EHA47884.1
Protein Name Nuclear distribution protein PAC1; Lissencephaly-1 homolog; nudF homolog
Genbank Nucleotide ID CM001236
Gene Name PAC1; LIS1; MGG_09369
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
MGG_09369 MGG_09369T0 MGG_09369T0
Status Unreviewed
Classification
Family E-Value Score Start End
E3 adaptor/Cullin RING/DCX/DWD 4.80e-49 161.6 115 150
UBD/Beta-Prp 6.20e-62 208.8 113 408
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvl 35
    H++ ++c+af + ++sGsdD+tik+WD+ g l
   Q: 115 HQNTINCIAFhPVySSIASGSDDCTIKIWDWELGEL 150
    99********955568**************876665 PP
   


   UBD/Beta-Prp

   S: 7    ghhksvitcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgk..ilvtgseDrtikvwdls.tgkcvhtlkghedsvlsls 101
    ++h++ i+c++f+p +s +a+gs+d tik+wd++ g l r++++h+ +v +v+f + +l+++s+D tik+wd+s ++k ++tl gh++sv +++
   Q: 113 ESHQNTINCIAFHPVYSSIASGSDDCTIKIWDWELGELERTIKSHTRPVLDVDFGGPRGgiLLASCSSDLTIKLWDPSdDYKNIRTLPGHDHSVSAIR 210
    578999************************************************866555899************88769****************** PP
   S: 102 fsp........sgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtl..tgghtdsvyslsfd 189
    f+p sg+ lvs+s+d t+++wd++tg cl+ t +gh+++++ v + dg++l s ++D+tvrlWdl+ + +l g h++++++ ++
   Q: 211 FMPsgasgaamSGNLLVSASRDMTLKIWDVSTGFCLK-TIRGHTAWIRDVYPSLDGRYLLSTGDDSTVRLWDLSVTNPENRLtmIG-HDHYIECCALA 306
    ***99999998899***********************.***********************************9999999997566.*********77 PP
   S: 190 sng.....................kelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfspnderlvsgssDgsiriWdlrs.gdllktlqlhns 265
    + + ++++sgs+d+t+klwd +g+ ++tl+gh+++v+ + f+p + +l+s+s+D+++r+Wdl++ g+++kt+ ++
   Q: 307 PPSsypflsrlaglkkppaatstaEFMASGSRDKTIKLWDA-RGTLLKTLIGHDNWVRALVFHPGGRYLLSVSDDKTLRCWDLEQdGKCVKTIGDVHE 403
    766777777778888888888888****************9.7889*************************************86379****999887 PP
   S: 266 svisv 270
    +++ +
   Q: 404 RFVTC 408
    66554 PP
   

Organism Magnaporthe oryzae
Functional Description
(View)

Functional Description



     Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for nuclear migration during vegetative growth as well as development. Required for retrograde early endosome (EE) transport from the hyphal tip. Required for localization of dynein to the mitotic spindle poles. Recruits additional proteins to the dynein complex at SPBs.
Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for nuclear migration during vegetative growth as well as development. Required for retrograde early endosome (EE) transport from the hyphal tip. Required for localization of dynein to the mitotic spindle poles. Recruits additional proteins to the dynein complex at SPBs.
Protein Sequence
(Fasta)
MTSILTPRQA EELHKAIIAY LSANNLSSSA TALRTELGLA EDVFDAATAK KYEGLIEKKW 60
TSVVRLQKKI MDLESRNNAL QSELDNATPL SLAKRNTDPT AWLPAPRPRY SLESHQNTIN 120
It may take some time, please wait.

Protein Fasta Sequence



>IUUC-Mor-056962|E3,WD_repeat;UBD,Beta-Prp|Magnaporthe oryzae
Please wait for a moment...
Nucleotide Sequence
(Fasta)
CATGCCCGTT GAAACACGGC GGTGGACGCC GACCGATTTT GCACCTTTTC CCGGCACCTG 60
AACTCAAACG GAAGAAGACG GACATACATT AACGACATAT TGAAGAGAAG CGTGCTGTAT 120
It may take some time, please wait.

Nucleotide Fasta Sequence



>IUUC-Mor-056962|E3,WD_repeat;UBD,Beta-Prp|Magnaporthe oryzae
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0131--Cell cycle
KW-0132--Cell division
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0206--Cytoskeleton
KW-0493--Microtubule
KW-0498--Mitosis
KW-1185--Reference proteome
KW-0677--Repeat
KW-0813--Transport
KW-0853--WD repeat

Interpro

IPR017252--Dynein_regulator_LIS1
IPR020472--G-protein_beta_WD-40_rep
IPR006594--LisH
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS50896--LISH
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005874--C:microtubule
GO:0000922--C:spindle pole
GO:0051301--P:cell division
GO:0007067--P:mitotic nuclear division
GO:0006810--P:transport

KEGG mgr:MGG_09369
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-001589 Ailuropoda melanoleuca 44.96 5.00e-98 349.00
IUUC-Apl-004024 Anas platyrhynchos 45.08 3.00e-101 360.00
IUUC-Aca-004564 Anolis carolinensis 44.60 5.00e-99 352.00
IUUC-Ago-007862 Ashbya gossypii 28.34 1.00e-39 155.00
IUUC-Acl-008360 Aspergillus clavatus 68.30 0.00e+00 639.00
IUUC-Afl-008502 Aspergillus flavus 65.40 2.00e-176 610.00
IUUC-Afu-008848 Aspergillus fumigatus 67.38 0.00e+00 664.00
IUUC-Ani-009173 Aspergillus nidulans 57.70 3.00e-157 546.00
IUUC-Ang-009873 Aspergillus niger 55.77 2.00e-151 526.00
IUUC-Aor-009973 Aspergillus oryzae 61.85 7.00e-169 585.00
IUUC-Ate-010523 Aspergillus terreus 57.95 3.00e-160 556.00
IUUC-Ame-011154 Astyanax mexicanus 44.60 2.00e-100 357.00
IUUC-Bgr-011972 Blumeria graminis 65.16 0.00e+00 652.00
IUUC-Bta-013106 Bos taurus 45.08 2.00e-101 360.00
IUUC-Bci-013615 Botrytis cinerea 68.66 0.00e+00 661.00
IUUC-Cel-018459 Caenorhabditis elegans 40.89 5.00e-86 309.00
IUUC-Cja-018755 Callithrix jacchus 44.12 3.00e-98 350.00
IUUC-Cfa-020749 Canis familiaris 45.08 2.00e-101 360.00
IUUC-Cpo-022371 Cavia porcellus 45.08 2.00e-101 360.00
IUUC-Csa-023524 Chlorocebus sabaeus 45.14 4.00e-84 303.00
IUUC-Cho-024764 Choloepus hoffmanni 41.89 3.00e-82 296.00
IUUC-Cin-025753 Ciona intestinalis 46.08 4.00e-96 342.00
IUUC-Csv-025817 Ciona savignyi 46.32 4.00e-99 352.00
IUUC-Cgl-026529 Colletotrichum gloeosporioides 71.71 0.00e+00 664.00
IUUC-Cne-027087 Cryptococcus neoformans 49.39 7.00e-106 375.00
IUUC-Dre-028314 Danio rerio 45.45 7.00e-101 358.00
IUUC-Dno-029050 Dasypus novemcinctus 45.08 2.00e-101 360.00
IUUC-Dor-030222 Dipodomys ordii 41.35 2.00e-91 327.00
IUUC-Dse-031164 Dothistroma septosporum 61.56 9.00e-175 604.00
IUUC-Dme-031745 Drosophila melanogaster 43.31 9.00e-90 322.00
IUUC-Ete-032508 Echinops telfairi 46.59 1.00e-67 248.00
IUUC-Eca-034288 Equus caballus 44.47 8.00e-97 345.00
IUUC-Eeu-034984 Erinaceus europaeus 41.11 2.00e-90 323.00
IUUC-Fca-036498 Felis catus 45.08 2.00e-101 360.00
IUUC-Fal-036920 Ficedula albicollis 45.08 3.00e-101 360.00
IUUC-Fox-037996 Fusarium oxysporum 70.28 0.00e+00 703.00
IUUC-Fso-038160 Fusarium solani 68.48 0.00e+00 670.00
IUUC-Gmo-038983 Gadus morhua 44.60 3.00e-100 356.00
IUUC-Ggr-040051 Gaeumannomyces graminis 87.72 0.00e+00 823.00
IUUC-Gga-040623 Gallus gallus 45.08 3.00e-101 360.00
IUUC-Gac-041613 Gasterosteus aculeatus 44.12 3.00e-100 357.00
IUUC-Ggo-045410 Gorilla gorilla 40.44 1.00e-81 295.00
IUUC-Hsa-046358 Homo sapiens 45.08 3.00e-101 360.00
IUUC-Itr-047890 Ictidomys tridecemlineatus 45.08 2.00e-101 360.00
IUUC-Kpa-049351 Komagataella pastoris 29.48 9.00e-45 172.00
IUUC-Lch-049936 Latimeria chalumnae 44.36 7.00e-101 358.00
IUUC-Loc-052476 Lepisosteus oculatus 44.96 6.00e-98 348.00
IUUC-Lma-053170 Leptosphaeria maculans 67.90 0.00e+00 625.00
IUUC-Laf-053713 Loxodonta africana 45.12 5.00e-99 352.00
IUUC-Mcc-054628 Macaca mulatta 45.08 4.00e-101 359.00
IUUC-Meu-055927 Macropus eugenii 39.43 5.00e-49 186.00
IUUC-Mpo-057583 Magnaporthe poae 88.15 0.00e+00 797.00
IUUC-Mla-058819 Melampsora laricipopulina 43.47 3.00e-108 383.00
IUUC-Mga-059945 Meleagris gallopavo 45.08 3.00e-101 360.00
IUUC-Mvi-060403 Microbotryum violaceum 47.21 5.00e-118 416.00
IUUC-Mmr-061289 Microcebus murinus 44.58 3.00e-98 350.00
IUUC-Mdo-061912 Monodelphis domestica 44.84 9.00e-101 358.00
IUUC-Mmu-063253 Mus musculus 45.08 2.00e-101 360.00
IUUC-Mpu-066638 Mustela putorius furo 45.08 2.00e-101 360.00
IUUC-Mlu-067267 Myotis lucifugus 44.26 2.00e-98 350.00
IUUC-Nfi-068571 Neosartorya fischeri 62.77 3.00e-173 599.00
IUUC-Ncr-068895 Neurospora crassa 71.27 0.00e+00 673.00
IUUC-Nle-069087 Nomascus leucogenys 43.79 5.00e-82 295.00
IUUC-Opr-070579 Ochotona princeps 45.08 2.00e-101 360.00
IUUC-Ont-071905 Oreochromis niloticus 44.12 4.00e-100 356.00
IUUC-Oan-073072 Ornithorhynchus anatinus 45.08 2.00e-101 360.00
IUUC-Ocu-074180 Oryctolagus cuniculus 45.08 2.00e-101 360.00
IUUC-Ola-086815 Oryzias latipes 44.87 8.00e-102 362.00
IUUC-Oga-088219 Otolemur garnettii 44.12 1.00e-98 351.00
IUUC-Oar-090394 Ovis aries 45.08 2.00e-101 360.00
IUUC-Ptr-091517 Pan troglodytes 45.08 2.00e-101 360.00
IUUC-Pan-092421 Papio anubis 45.08 4.00e-101 359.00
IUUC-Psi-093370 Pelodiscus sinensis 45.08 5.00e-101 359.00
IUUC-Pma-094319 Petromyzon marinus 43.06 4.00e-82 296.00
IUUC-Pno-094815 Phaeosphaeria nodorum 67.31 0.00e+00 638.00
IUUC-Pfo-097089 Poecilia formosa 45.08 1.00e-101 361.00
IUUC-Pab-098421 Pongo abelii 45.08 2.00e-101 360.00
IUUC-Pca-100120 Procavia capensis 36.21 2.00e-55 207.00
IUUC-Pva-102960 Pteropus vampyrus 44.84 3.00e-100 357.00
IUUC-Pgr-103538 Puccinia graminis 47.11 5.00e-118 416.00
IUUC-Ptt-103990 Puccinia triticina 43.35 1.00e-46 179.00
IUUC-Pte-104261 Pyrenophora teres 67.46 0.00e+00 638.00
IUUC-Pyt-104780 Pyrenophora triticirepentis 67.67 0.00e+00 639.00
IUUC-Rno-105123 Rattus norvegicus 45.08 2.00e-101 360.00
IUUC-Sce-106208 Saccharomyces cerevisiae 26.98 9.00e-37 146.00
IUUC-Sha-107010 Sarcophilus harrisii 45.08 4.00e-101 359.00
IUUC-Sja-107899 Schizosaccharomyces japonicus 35.31 2.00e-68 251.00
IUUC-Ssl-108571 Sclerotinia sclerotiorum 70.78 0.00e+00 645.00
IUUC-Sar-113309 Sorex araneus 44.23 3.00e-95 340.00
IUUC-Sre-115003 Sporisorium reilianum 46.55 7.00e-119 418.00
IUUC-Ssc-116148 Sus scrofa 45.08 2.00e-101 360.00
IUUC-Tgu-117299 Taeniopygia guttata 45.08 2.00e-101 360.00
IUUC-Tru-117721 Takifugu rubripes 44.36 1.00e-100 358.00
IUUC-Tsy-119493 Tarsius syrichta 44.60 7.00e-99 352.00
IUUC-Tni-120355 Tetraodon nigroviridis 44.12 7.00e-99 352.00
IUUC-Tre-121977 Trichoderma reesei 65.41 0.00e+00 633.00
IUUC-Tvi-122661 Trichoderma virens 65.25 2.00e-179 620.00
IUUC-Tme-127031 Tuber melanosporum 63.68 4.00e-176 608.00
IUUC-Tbe-127492 Tupaia belangeri 40.89 2.00e-46 177.00
IUUC-Ttr-128929 Tursiops truncatus 45.08 2.00e-101 360.00
IUUC-Uma-129347 Ustilago maydis 47.52 2.00e-117 413.00
IUUC-Vda-129837 Verticillium dahliae 67.74 0.00e+00 635.00
IUUC-Vpa-130532 Vicugna pacos 38.18 4.00e-80 290.00
IUUC-Xtr-131985 Xenopus tropicalis 44.60 9.00e-101 358.00
IUUC-Xma-133314 Xiphophorus maculatus 44.84 3.00e-101 360.00
IUUC-Yli-134403 Yarrowia lipolytica 40.21 9.00e-95 338.00
Created Date 25-Jun-2017

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