iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mdo-062895

Ensembl Protein ID

ENSMODP00000018697.2

UniProt Accession

F7FI75; F7FI75_MONDO

Protein Name

Uncharacterized protein

Gene Name

NWD1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMODG00000014951.2	ENSMODT00000019034.2	ENSMODP00000018697.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	2.90e-16	59.1	908	943
UBD/Beta-Prp	5.00e-45	154.1	859	1049

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtcla.f.sdtllvsGsdDgtikvWDlrtgv 34
           gHt++v+c++ f  + + +s+s D t++ W+l +g+
   Q: 908  GHTGEVRCVKtFgEGIYAISASKDRTLRTWNLVSGK 943
           8********878522459**************9997 PP

UBD/Beta-Prp

   S: 45   lrslsgheaevtavkfspdgkilvtgseDrtikvw..dlstgkcvhtlkghedsvlslsfspsgdklvsGshdrtirvwdletgqcl 129
            ++l g  +++ta+++s+   +l+ gs+ +++ vw    + ++ vh+l+gh+ +v++++ + +g + +s+s+drt+r w+l +g++ 
   Q: 859  QETLTGYHKGITALEWSSINRLLIVGSQNGVLVVWvmKEKESQVVHVLTGHTGEVRCVKTFGEGIYAISASKDRTLRTWNLVSGKEK 945
           578888899999999999999999999999999996555589999999999999999999999999999999999999999999998 PP
   S: 130  ee.....tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsvyslsfdsngkelvsgsldgtvklwdlqt 211
           +        ++++   +c++v+++++++ s s  ++v+ W+l+t++ + +  g+ +d+  + ++ s++  +v+ s+ g v  wd +t
   Q: 946  YViqngiSADPREPHFCCLHVDEKNKVVYS-SSSSKVNAWNLETAEAIFHIMGDAQDPWVWATVFSSSSGIVTLSKEGFVSTWDART 1031
           885556555555556789999996665555.55688999999999999999888999999999777788999999999999999999 PP
   S: 212  gecvrtlnghtdnvksvrfs 231
           g+   + ++h + +k  +++
   Q: 1032 GK--SRSKNHLSSMKEEALT 1049
           97..5556666655555554 PP

Organism

Monodelphis domestica

Protein Sequence
(Fasta)

QTFCQKHGLM LEVVDLRWGL RTWEAMDHTT IDLCLEELAM CQKLSAGPTF IALVGDQYGH 60
CPIPRLIEEK EFQALCAQLT KNPNSLTLLA QWFWKDENAV PPVYILQPIT THLPQYEKQH 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CAGACCTTTT GTCAGAAGCA CGGCTTAATG TTGGAGGTAA CATTTGCTTT TCTGGTCTTG 60
TCATTGGGGC AAGTTCTTTG TGGGTGAACA GAATAATTCA GGGGGTCGGA GGAATGGGAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR027417--P-loop_NTPase
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0071013--C:catalytic step 2 spliceosome
GO:0071011--C:precatalytic spliceosome
GO:0005682--C:U5 snRNP
GO:0008380--P:RNA splicing

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001525	Ailuropoda melanoleuca	62.61	0.00e+00	1816.00
IUUC-Apl-003467	Anas platyrhynchos	58.70	1.00e-61	229.00
IUUC-Ame-011400	Astyanax mexicanus	37.37	0.00e+00	954.00
IUUC-Bta-013223	Bos taurus	62.53	0.00e+00	1560.00
IUUC-Cel-018404	Caenorhabditis elegans	30.28	1.00e-111	398.00
IUUC-Cja-018773	Callithrix jacchus	61.23	0.00e+00	1028.00
IUUC-Cfa-020334	Canis familiaris	62.96	0.00e+00	1847.00
IUUC-Cpo-022316	Cavia porcellus	53.69	0.00e+00	1432.00
IUUC-Csa-023631	Chlorocebus sabaeus	61.25	0.00e+00	1769.00
IUUC-Cin-025646	Ciona intestinalis	31.03	3.00e-125	442.00
IUUC-Csv-026191	Ciona savignyi	24.62	3.00e-20	92.40
IUUC-Dre-028241	Danio rerio	36.93	0.00e+00	911.00
IUUC-Dno-029990	Dasypus novemcinctus	63.64	4.00e-113	401.00
IUUC-Dor-030869	Dipodomys ordii	50.92	2.00e-144	506.00
IUUC-Ete-033059	Echinops telfairi	66.34	0.00e+00	681.00
IUUC-Eca-033718	Equus caballus	59.59	0.00e+00	1731.00
IUUC-Fca-035748	Felis catus	61.85	0.00e+00	1849.00
IUUC-Gac-041507	Gasterosteus aculeatus	35.61	0.00e+00	793.00
IUUC-Ggo-044551	Gorilla gorilla	59.92	0.00e+00	1739.00
IUUC-Hsa-046787	Homo sapiens	61.20	0.00e+00	1781.00
IUUC-Itr-048104	Ictidomys tridecemlineatus	54.50	0.00e+00	875.00
IUUC-Lch-049578	Latimeria chalumnae	51.36	0.00e+00	1436.00
IUUC-Loc-052039	Lepisosteus oculatus	44.22	0.00e+00	1219.00
IUUC-Laf-054240	Loxodonta africana	62.35	0.00e+00	1843.00
IUUC-Mcc-054657	Macaca mulatta	55.36	0.00e+00	1473.00
IUUC-Meu-056591	Macropus eugenii	82.97	0.00e+00	1505.00
IUUC-Mmr-061577	Microcebus murinus	58.75	0.00e+00	1689.00
IUUC-Mmu-063866	Mus musculus	58.92	0.00e+00	1685.00
IUUC-Mpu-066510	Mustela putorius furo	62.04	0.00e+00	1829.00
IUUC-Mlu-067855	Myotis lucifugus	62.54	0.00e+00	1751.00
IUUC-Nle-069557	Nomascus leucogenys	58.11	0.00e+00	1614.00
IUUC-Opr-071196	Ochotona princeps	49.06	2.00e-139	490.00
IUUC-Ont-072070	Oreochromis niloticus	35.98	0.00e+00	768.00
IUUC-Oan-073437	Ornithorhynchus anatinus	64.83	0.00e+00	1431.00
IUUC-Ocu-074941	Oryctolagus cuniculus	53.79	3.00e-36	144.00
IUUC-Ola-086624	Oryzias latipes	33.52	0.00e+00	660.00
IUUC-Oga-088313	Otolemur garnettii	62.11	0.00e+00	1781.00
IUUC-Oar-090123	Ovis aries	61.76	0.00e+00	1774.00
IUUC-Ptr-090552	Pan troglodytes	63.51	0.00e+00	694.00
IUUC-Psi-093963	Pelodiscus sinensis	57.76	0.00e+00	1698.00
IUUC-Pfo-096197	Poecilia formosa	34.95	0.00e+00	776.00
IUUC-Pab-097755	Pongo abelii	61.50	0.00e+00	724.00
IUUC-Pca-100809	Procavia capensis	61.66	0.00e+00	969.00
IUUC-Pva-102554	Pteropus vampyrus	60.42	0.00e+00	1684.00
IUUC-Rno-105174	Rattus norvegicus	53.22	0.00e+00	1434.00
IUUC-Sha-107304	Sarcophilus harrisii	88.33	0.00e+00	2577.00
IUUC-Sar-113168	Sorex araneus	54.52	0.00e+00	719.00
IUUC-Tru-118251	Takifugu rubripes	39.20	3.00e-163	570.00
IUUC-Tsy-119276	Tarsius syrichta	64.07	4.00e-98	353.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence