iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Apl-003594

Ensembl Protein ID

ENSAPLP00000012218.1

UniProt Accession

U3IY92; U3IY92_ANAPL

Genbank Protein ID

ENSAPLP00000012218

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ADON01078139

Gene Name

TLE1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAPLG00000012402.1	ENSAPLT00000012953.1	ENSAPLP00000012218.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.40e-22	78.6	563	601

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvllk 37
           gHtd+ +c++  +d t l++G+ D+t++ WDlr+g++l+
   Q: 563  GHTDGASCIDIsNDgTKLWTGGLDNTVRSWDLREGRQLQ 601
           8***********999*********************998 PP

Organism

Anas platyrhynchos

Protein Sequence
(Fasta)

SLKLECEKLA SEKTEMQRHY VMYYEMSYGL NIEMHKQTEI AKRLNTICAQ VIPFLSQEHQ 60
QQVAQAVERA KQVTMAELNA IIGQQQLQAQ HLSHGHGPPV PLTPHPSGLQ PSGIPPLGSS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AGCCTTAAAT TGGAATGTGA GAAACTGGCA AGCGAAAAGA CAGAAATGCA GAGGCACTAT 60
GTGATGGTAT GTATGTTTGT TTTTCTTTGT TTCAGTAAAT ATCTTCTAAT GCAATGTAAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR011042--6-blade_b-propeller_TolB-like
IPR005617--Groucho/TLE_N
IPR009146--Groucho_enhance
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF03920--TLE_N
PF00400--WD40

PRINTS

PR01850--GROUCHOFAMLY

SMART

SM00320--WD40

Gene Ontology

GO:0005829--C:cytosol
GO:0005654--C:nucleoplasm
GO:0001106--F:RNA polymerase II transcription corepressor activity
GO:2000811--P:negative regulation of anoikis
GO:0043124--P:negative regulation of I-kappaB kinase/NF-kappaB signaling
GO:0010628--P:positive regulation of gene expression

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001746	Ailuropoda melanoleuca	91.55	0.00e+00	1136.00
IUUC-Aca-005053	Anolis carolinensis	90.15	0.00e+00	1176.00
IUUC-Ame-010724	Astyanax mexicanus	75.70	0.00e+00	1011.00
IUUC-Cel-018361	Caenorhabditis elegans	59.71	4.00e-119	421.00
IUUC-Cja-019135	Callithrix jacchus	94.53	0.00e+00	1179.00
IUUC-Cfa-020611	Canis familiaris	94.55	0.00e+00	1149.00
IUUC-Cpo-022495	Cavia porcellus	93.98	0.00e+00	1176.00
IUUC-Csa-024056	Chlorocebus sabaeus	94.39	0.00e+00	1196.00
IUUC-Cin-025767	Ciona intestinalis	57.64	4.00e-170	591.00
IUUC-Csv-026174	Ciona savignyi	56.54	3.00e-160	558.00
IUUC-Dre-028595	Danio rerio	77.00	0.00e+00	1017.00
IUUC-Dno-029011	Dasypus novemcinctus	95.21	0.00e+00	1182.00
IUUC-Dor-030533	Dipodomys ordii	79.26	0.00e+00	1024.00
IUUC-Dme-031576	Drosophila melanogaster	86.03	0.00e+00	660.00
IUUC-Ete-032533	Echinops telfairi	84.72	0.00e+00	1078.00
IUUC-Eca-033351	Equus caballus	94.80	0.00e+00	1181.00
IUUC-Eeu-034666	Erinaceus europaeus	94.97	0.00e+00	1040.00
IUUC-Fal-036696	Ficedula albicollis	96.23	0.00e+00	1239.00
IUUC-Gmo-038805	Gadus morhua	78.66	0.00e+00	1075.00
IUUC-Gga-041113	Gallus gallus	96.17	0.00e+00	1254.00
IUUC-Gac-041999	Gasterosteus aculeatus	78.91	0.00e+00	1085.00
IUUC-Ggo-045164	Gorilla gorilla	94.53	0.00e+00	1197.00
IUUC-Hsa-047011	Homo sapiens	94.53	0.00e+00	1197.00
IUUC-Itr-048040	Ictidomys tridecemlineatus	91.71	0.00e+00	1140.00
IUUC-Lch-050437	Latimeria chalumnae	91.32	0.00e+00	1097.00
IUUC-Loc-052819	Lepisosteus oculatus	87.47	0.00e+00	1109.00
IUUC-Laf-053862	Loxodonta africana	90.15	0.00e+00	1144.00
IUUC-Mcc-055735	Macaca mulatta	90.33	0.00e+00	1181.00
IUUC-Mga-059792	Meleagris gallopavo	74.06	0.00e+00	866.00
IUUC-Mmr-061207	Microcebus murinus	91.50	0.00e+00	1137.00
IUUC-Mdo-062493	Monodelphis domestica	95.62	0.00e+00	1237.00
IUUC-Mmu-063795	Mus musculus	90.31	0.00e+00	1144.00
IUUC-Mpu-065819	Mustela putorius furo	94.81	0.00e+00	1212.00
IUUC-Mlu-067047	Myotis lucifugus	94.80	0.00e+00	1164.00
IUUC-Nle-069684	Nomascus leucogenys	94.53	0.00e+00	1192.00
IUUC-Opr-071172	Ochotona princeps	94.39	0.00e+00	1180.00
IUUC-Ont-072102	Oreochromis niloticus	79.11	0.00e+00	1094.00
IUUC-Oan-072842	Ornithorhynchus anatinus	82.63	0.00e+00	1106.00
IUUC-Ocu-074592	Oryctolagus cuniculus	90.33	0.00e+00	1182.00
IUUC-Ola-087267	Oryzias latipes	77.64	0.00e+00	1013.00
IUUC-Oga-088629	Otolemur garnettii	90.28	0.00e+00	1139.00
IUUC-Oar-089551	Ovis aries	94.26	0.00e+00	1172.00
IUUC-Ptr-091207	Pan troglodytes	94.38	0.00e+00	1192.00
IUUC-Pan-091822	Papio anubis	90.33	0.00e+00	1181.00
IUUC-Psi-093594	Pelodiscus sinensis	93.12	0.00e+00	1195.00
IUUC-Pma-094452	Petromyzon marinus	76.81	0.00e+00	1046.00
IUUC-Pfo-096239	Poecilia formosa	79.14	0.00e+00	1087.00
IUUC-Pab-097687	Pongo abelii	94.53	0.00e+00	1198.00
IUUC-Pca-100675	Procavia capensis	94.41	0.00e+00	1021.00
IUUC-Pva-102355	Pteropus vampyrus	91.24	0.00e+00	1103.00
IUUC-Rno-106027	Rattus norvegicus	93.18	0.00e+00	1195.00
IUUC-Sha-107419	Sarcophilus harrisii	95.50	0.00e+00	1240.00
IUUC-Sar-113585	Sorex araneus	83.61	0.00e+00	705.00
IUUC-Ssc-116151	Sus scrofa	95.08	0.00e+00	1184.00
IUUC-Tgu-117387	Taeniopygia guttata	95.21	0.00e+00	1221.00
IUUC-Tru-118051	Takifugu rubripes	75.13	0.00e+00	1037.00
IUUC-Tsy-119342	Tarsius syrichta	85.73	0.00e+00	978.00
IUUC-Tni-120823	Tetraodon nigroviridis	80.27	0.00e+00	1044.00
IUUC-Tbe-127881	Tupaia belangeri	91.52	0.00e+00	1165.00
IUUC-Xtr-131792	Xenopus tropicalis	86.96	0.00e+00	1125.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence