iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Oan-072842

Ensembl Protein ID

ENSOANP00000012515.2

UniProt Accession

F7EFU4; F7EFU4_ORNAN

Protein Name

Uncharacterized protein

Gene Name

TLE4

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOANG00000007857.2	ENSOANT00000012517.2	ENSOANP00000012515.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	8.70e-23	79.7	638	676
UBD/Beta-Prp	3.20e-40	138.4	506	675

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvllk 37
           gHtd+ +c++  +d t l++G+ D+t++ WDlr+g++l+
   Q: 638  GHTDGASCIDIsNDgTKLWTGGLDNTVRSWDLREGRQLQ 676
           8***********999*********************998 PP

UBD/Beta-Prp

   S: 50   gheaevtavkfspdgkilvtgseDrtikvwdls...tgkcvhtlk..ghedsvlslsfspsgdklvsGshdrtirvwdletgqclee.t 132
           +h + v av++s+ +   v ++  + +kvwd+s   + ++v+ l   + +++++s+++ p+g +l++G++ +t+ +wdl   +   +  
   Q: 506  NHGEVVCAVTISNPTR-HVYTGGKGCVKVWDISqpgNKSPVSQLDclNRDNYIRSCKLLPDGRTLIVGGEASTLSIWDLAAPTPRIKaE 593
           5666788899999885.555555579*******998888888888889*******************************9988766658 PP
   S: 133  lsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgecv 215
           l+    +   ++++pd+++++s++ D+ + +Wdl +++l+r+++g htd   +++++ +g+ l +g+ld+tv+ wdl++g+ +
   Q: 594  LTSSAPACYALAISPDSKVCFSCCSDGNIAVWDLHNQTLVRQFQG-HTDGASCIDISNDGTKLWTGGLDNTVRSWDLREGRQL 675
           88888888999*********************************9.********************************99754 PP

Organism

Ornithorhynchus anatinus

Protein Sequence
(Fasta)

MIRDLSKMYP QSRHPAPHQP AQPFKFTISE SCDRIKEEFQ FLQAQYHSLK LECEKLASEK 60
TEMQRHYVMY YEMSYGLNIE MHKQAEIVKR LNAICAQVIP FLSQEHQQQV VQAVERAKQV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGATTCGCG ATCTGAGCAA GATGTATCCT CAAAGCAGAC ACCCGGTGAG TGAGAGTCTC 60
CACCGGCCGC GGGTCCGCCG GGGCTGGGAG GTGATGACTT TGCCCGGGAG AGAGAGGGCA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR005617--Groucho/TLE_N
IPR009146--Groucho_enhance
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF03920--TLE_N
PF00400--WD40

PRINTS

PR01850--GROUCHOFAMLY

SMART

SM00320--WD40

Gene Ontology

GO:0005634--C:nucleus
GO:0006355--P:regulation of transcription, DNA-templated

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001746	Ailuropoda melanoleuca	82.72	0.00e+00	1113.00
IUUC-Apl-003594	Anas platyrhynchos	82.63	0.00e+00	1093.00
IUUC-Aca-005279	Anolis carolinensis	95.72	0.00e+00	1318.00
IUUC-Ame-010724	Astyanax mexicanus	76.81	0.00e+00	1111.00
IUUC-Bta-012646	Bos taurus	95.22	0.00e+00	1338.00
IUUC-Cel-018361	Caenorhabditis elegans	60.96	1.00e-119	422.00
IUUC-Cja-019079	Callithrix jacchus	95.59	0.00e+00	1379.00
IUUC-Cfa-020987	Canis familiaris	95.59	0.00e+00	1329.00
IUUC-Cpo-021606	Cavia porcellus	93.52	0.00e+00	1295.00
IUUC-Csa-023445	Chlorocebus sabaeus	95.97	0.00e+00	1353.00
IUUC-Cho-024590	Choloepus hoffmanni	82.67	0.00e+00	1188.00
IUUC-Cin-025767	Ciona intestinalis	56.63	3.00e-164	572.00
IUUC-Csv-026174	Ciona savignyi	80.66	7.00e-157	547.00
IUUC-Dre-028595	Danio rerio	77.40	0.00e+00	1103.00
IUUC-Dno-028979	Dasypus novemcinctus	95.66	0.00e+00	1306.00
IUUC-Dor-030533	Dipodomys ordii	91.11	0.00e+00	1134.00
IUUC-Dme-031576	Drosophila melanogaster	81.79	0.00e+00	656.00
IUUC-Ete-032887	Echinops telfairi	82.32	0.00e+00	1187.00
IUUC-Eca-034397	Equus caballus	95.45	0.00e+00	1246.00
IUUC-Eeu-034666	Erinaceus europaeus	84.30	0.00e+00	920.00
IUUC-Fca-036030	Felis catus	95.77	0.00e+00	1345.00
IUUC-Fal-037460	Ficedula albicollis	95.76	0.00e+00	1326.00
IUUC-Gmo-038805	Gadus morhua	76.52	0.00e+00	1096.00
IUUC-Gga-040416	Gallus gallus	95.97	0.00e+00	1354.00
IUUC-Gac-042392	Gasterosteus aculeatus	77.25	0.00e+00	1128.00
IUUC-Ggo-045633	Gorilla gorilla	92.11	0.00e+00	1321.00
IUUC-Hsa-046461	Homo sapiens	92.13	0.00e+00	1352.00
IUUC-Itr-048974	Ictidomys tridecemlineatus	95.85	0.00e+00	1350.00
IUUC-Lch-049943	Latimeria chalumnae	93.45	0.00e+00	1228.00
IUUC-Loc-052835	Lepisosteus oculatus	93.10	0.00e+00	1261.00
IUUC-Laf-053425	Loxodonta africana	96.15	0.00e+00	1352.00
IUUC-Mcc-055766	Macaca mulatta	92.25	0.00e+00	1354.00
IUUC-Meu-056601	Macropus eugenii	78.39	0.00e+00	1113.00
IUUC-Mga-059792	Meleagris gallopavo	72.28	0.00e+00	863.00
IUUC-Mmr-061317	Microcebus murinus	92.70	0.00e+00	1355.00
IUUC-Mdo-062956	Monodelphis domestica	96.10	0.00e+00	1349.00
IUUC-Mmu-063576	Mus musculus	95.72	0.00e+00	1346.00
IUUC-Mpu-066410	Mustela putorius furo	95.77	0.00e+00	1251.00
IUUC-Mlu-067456	Myotis lucifugus	93.98	0.00e+00	1269.00
IUUC-Nle-069495	Nomascus leucogenys	96.02	0.00e+00	1323.00
IUUC-Opr-071172	Ochotona princeps	83.46	0.00e+00	1111.00
IUUC-Ont-071419	Oreochromis niloticus	83.71	0.00e+00	1172.00
IUUC-Ocu-074453	Oryctolagus cuniculus	94.58	0.00e+00	1330.00
IUUC-Ola-087090	Oryzias latipes	83.31	0.00e+00	1178.00
IUUC-Oga-087939	Otolemur garnettii	95.72	0.00e+00	1348.00
IUUC-Oar-090347	Ovis aries	95.23	0.00e+00	1221.00
IUUC-Ptr-091048	Pan troglodytes	95.97	0.00e+00	1353.00
IUUC-Pan-091973	Papio anubis	91.44	0.00e+00	1299.00
IUUC-Psi-093594	Pelodiscus sinensis	81.91	0.00e+00	1105.00
IUUC-Pma-094452	Petromyzon marinus	78.25	0.00e+00	917.00
IUUC-Pfo-097518	Poecilia formosa	82.38	0.00e+00	1123.00
IUUC-Pab-097539	Pongo abelii	91.75	0.00e+00	1225.00
IUUC-Pca-101137	Procavia capensis	84.96	0.00e+00	1115.00
IUUC-Pva-102355	Pteropus vampyrus	86.63	0.00e+00	879.00
IUUC-Rno-105314	Rattus norvegicus	95.52	0.00e+00	1276.00
IUUC-Sha-107419	Sarcophilus harrisii	81.09	0.00e+00	1115.00
IUUC-Sar-113585	Sorex araneus	78.72	0.00e+00	669.00
IUUC-Ssc-116408	Sus scrofa	95.49	0.00e+00	1368.00
IUUC-Tgu-117068	Taeniopygia guttata	95.34	0.00e+00	1321.00
IUUC-Tru-118782	Takifugu rubripes	80.47	0.00e+00	1130.00
IUUC-Tsy-118884	Tarsius syrichta	82.78	0.00e+00	1061.00
IUUC-Tni-120404	Tetraodon nigroviridis	81.88	0.00e+00	1169.00
IUUC-Tbe-128013	Tupaia belangeri	88.12	0.00e+00	1248.00
IUUC-Ttr-128845	Tursiops truncatus	78.07	0.00e+00	1122.00
IUUC-Vpa-130577	Vicugna pacos	89.77	0.00e+00	709.00
IUUC-Xtr-132974	Xenopus tropicalis	93.37	0.00e+00	1266.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence