iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Pyt-104550

Ensembl Protein ID

EDU47052

UniProt Accession

B2W179; B2W179_PYRTR

Genbank Protein ID

EDU47052.1

Protein Name

E3 ubiquitin-protein ligase

Genbank Nucleotide ID

DS231617

Gene Name

PTRG_04214

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
PTRG_04214	EDU47052	EDU47052

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	3.50e-126	420.4	485	816

Active Site

Position(s)	Description	Evidence
785	Glycyl thioester intermediate	{ECO:0000256\|PIRSR:PIRSR001569-1, ECO:0000256\|PROSITE-ProRule:PRU00104}

Domain Profile

E3 activity/HECT

   S: 2    ksdlkkrlevefvgEegldlgGvtreflallskelqnpdlglflysendketlqpnpdsglknpehlklFeflGrllgkalqdgrlldlplsksfyklllg 102
           ++dlkkrl+++f gE+gld+gG++ref++lls+e++np ++lf+ys+ d++tlq+np+sg+ npehl++F+f+Gr++g+a++++r+ld+++  +fyk++l+
   Q: 485  AADLKKRLMIKFDGEDGLDYGGLSREFFFLLSHEMFNPFYCLFEYSAHDNYTLQINPHSGI-NPEHLNYFKFIGRVVGLAIFHRRFLDAFFIGAFYKMILR 584
           689*********************************************************9.89************************************* PP
   S: 103  kklsledleevdpelykslkeikenaesdieelgldltfsvseeilgetkeeeLkpgGenipVtneNkeeYvklvveyrlkegikeqveafreGfnevipl 203
           kk+ l+d+e vd++++++l+++++n   di+++ l+ltf +++e +get + eLkpgG++i+VtneNk+eYv+l++e+r++++++eq++af  Gf+e+ip 
   Q: 585  KKVALQDMEGVDADFHRNLEWMLNN---DITDA-LELTFATDDERFGETVSIELKPGGDEIEVTNENKHEYVELITEWRIQKRVEEQFQAFITGFHELIPA 681
           ***********************99...9***8.******************************************************************* PP
   S: 204  ellslFteeelellicGeeeidvedlkketkykggytedspaiqwFwevleefsseerkafLqFvTgssrlPlgGfaelk....prlfvirkdasddrlPs 300
           +l+++F+e+elelli G ++idved+kk+t y+g yte++++iq+Fw++++++++e+++++LqF+Tg+sr+P++Gf++l+    pr+f+i+k++++++lP+
   Q: 682  DLVNVFDERELELLIGGIADIDVEDWKKHTDYRG-YTENDEVIQNFWKCIRSWDAEQKSRLLQFATGTSRIPVNGFKDLQgsdgPRRFTIEKAGEPNQLPK 781
           ********************************76.****************************************************************** PP
   S: 301  snTCfnyLkLPeYsskeilkekLlyAieetkgFel 335
           s+TCfn+L+LP+Y++ e l++kL++A+eet gF++
   Q: 782  SHTCFNRLDLPPYKTFEALNQKLTIAVEETVGFGQ 816
           *********************************96 PP

Organism

Pyrenophora triticirepentis

Protein Sequence
(Fasta)

MDGAGQPNLR ITIIAADGLY KRDVFRFPDP FAVATINGEQ TRTTSVIKKT LNPYWNESFD 60
MKVNEESVLA VQIFDQKKFK KKDQGFLGVI NVRIGSVIDL DAGGDEMLTR DLKKSNDNMV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGACGGCG CTGGCCAGCC CAACCTGCGC ATCACCAGTA CGTCTTTACC TCGGACTGCA 60
AGCCTCCATG GCCGTCTGCG AAGAGGGAAG CTGACAGTAC ATAGTCATTG CCGCCGATGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0436--Ligase
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR000008--C2_dom
IPR024928--E3_ub_ligase_SMURF1
IPR000569--HECT_dom
IPR001202--WW_dom

PROSITE

PS50004--C2
PS50237--HECT
PS01159--WW_DOMAIN_1
PS50020--WW_DOMAIN_2

Pfam

PF00168--C2
PF00632--HECT
PF00397--WW

SMART

SM00239--C2
SM00119--HECTc
SM00456--WW

Gene Ontology

GO:0016874--F:ligase activity
GO:0004842--F:ubiquitin-protein transferase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001314	Ailuropoda melanoleuca	48.17	1.00e-156	545.00
IUUC-Apl-003886	Anas platyrhynchos	47.51	9.00e-157	545.00
IUUC-Aca-005338	Anolis carolinensis	47.00	4.00e-153	533.00
IUUC-Ago-007742	Ashbya gossypii	74.62	0.00e+00	908.00
IUUC-Acl-008273	Aspergillus clavatus	76.39	0.00e+00	1196.00
IUUC-Afl-008713	Aspergillus flavus	75.79	0.00e+00	1172.00
IUUC-Afu-009103	Aspergillus fumigatus	74.14	0.00e+00	1149.00
IUUC-Ani-009259	Aspergillus nidulans	73.50	0.00e+00	1194.00
IUUC-Ang-009738	Aspergillus niger	75.12	0.00e+00	1196.00
IUUC-Aor-010053	Aspergillus oryzae	83.95	8.00e-155	537.00
IUUC-Ate-010529	Aspergillus terreus	75.42	0.00e+00	1202.00
IUUC-Ame-010810	Astyanax mexicanus	52.58	3.00e-144	504.00
IUUC-Bgr-012148	Blumeria graminis	71.82	0.00e+00	1124.00
IUUC-Bta-012679	Bos taurus	48.17	5.00e-157	546.00
IUUC-Bci-013785	Botrytis cinerea	75.85	0.00e+00	1184.00
IUUC-Cel-018299	Caenorhabditis elegans	43.76	2.00e-145	508.00
IUUC-Cja-018732	Callithrix jacchus	48.17	5.00e-157	546.00
IUUC-Cfa-021226	Canis familiaris	48.17	6.00e-157	546.00
IUUC-Cpo-021671	Cavia porcellus	48.17	4.00e-157	546.00
IUUC-Csa-023334	Chlorocebus sabaeus	53.32	1.00e-152	531.00
IUUC-Cho-024695	Choloepus hoffmanni	47.77	2.00e-155	541.00
IUUC-Cin-025212	Ciona intestinalis	45.41	6.00e-147	513.00
IUUC-Csv-026256	Ciona savignyi	46.01	4.00e-146	509.00
IUUC-Cgl-026642	Colletotrichum gloeosporioides	74.97	0.00e+00	1136.00
IUUC-Cne-026849	Cryptococcus neoformans	71.81	0.00e+00	867.00
IUUC-Dre-027770	Danio rerio	53.20	4.00e-146	510.00
IUUC-Dno-029466	Dasypus novemcinctus	48.34	2.00e-157	548.00
IUUC-Dor-030138	Dipodomys ordii	47.52	2.00e-151	528.00
IUUC-Dse-031241	Dothistroma septosporum	79.03	0.00e+00	1263.00
IUUC-Dme-032041	Drosophila melanogaster	46.36	3.00e-143	501.00
IUUC-Ete-033145	Echinops telfairi	45.35	6.00e-144	503.00
IUUC-Eca-033445	Equus caballus	48.17	1.00e-156	545.00
IUUC-Eeu-035247	Erinaceus europaeus	48.18	3.00e-156	544.00
IUUC-Fca-036384	Felis catus	49.15	7.00e-162	563.00
IUUC-Fal-037547	Ficedula albicollis	48.63	4.00e-155	540.00
IUUC-Fox-037774	Fusarium oxysporum	72.44	0.00e+00	1135.00
IUUC-Fso-038393	Fusarium solani	80.37	0.00e+00	951.00
IUUC-Gmo-039674	Gadus morhua	51.34	3.00e-143	501.00
IUUC-Ggr-040107	Gaeumannomyces graminis	74.45	0.00e+00	1164.00
IUUC-Gga-040524	Gallus gallus	49.14	6.00e-157	546.00
IUUC-Gac-042020	Gasterosteus aculeatus	47.50	7.00e-152	529.00
IUUC-Ggo-045332	Gorilla gorilla	48.17	1.00e-156	545.00
IUUC-Hsa-045968	Homo sapiens	48.17	4.00e-157	546.00
IUUC-Itr-048918	Ictidomys tridecemlineatus	46.75	2.00e-152	531.00
IUUC-Kpa-049273	Komagataella pastoris	66.59	0.00e+00	1050.00
IUUC-Lch-050443	Latimeria chalumnae	47.34	3.00e-154	537.00
IUUC-Loc-052645	Lepisosteus oculatus	48.24	9.00e-156	542.00
IUUC-Lma-052980	Leptosphaeria maculans	90.46	0.00e+00	862.00
IUUC-Laf-053850	Loxodonta africana	48.17	1.00e-156	545.00
IUUC-Mcc-055821	Macaca mulatta	48.17	8.00e-157	546.00
IUUC-Meu-055953	Macropus eugenii	40.10	2.00e-117	415.00
IUUC-Mor-057097	Magnaporthe oryzae	74.11	0.00e+00	1165.00
IUUC-Mpo-057442	Magnaporthe poae	82.31	0.00e+00	912.00
IUUC-Mla-058996	Melampsora laricipopulina	68.25	0.00e+00	864.00
IUUC-Mga-059362	Meleagris gallopavo	48.48	6.00e-157	546.00
IUUC-Mvi-060395	Microbotryum violaceum	79.58	0.00e+00	828.00
IUUC-Mmr-061061	Microcebus murinus	49.15	1.00e-164	572.00
IUUC-Mdo-062173	Monodelphis domestica	46.22	1.00e-152	532.00
IUUC-Mmu-064136	Mus musculus	48.17	4.00e-157	547.00
IUUC-Mpu-066765	Mustela putorius furo	48.17	8.00e-157	546.00
IUUC-Mlu-068148	Myotis lucifugus	48.21	8.00e-162	563.00
IUUC-Nfi-068427	Neosartorya fischeri	83.06	0.00e+00	1024.00
IUUC-Ncr-068918	Neurospora crassa	81.69	0.00e+00	959.00
IUUC-Nle-069225	Nomascus leucogenys	48.11	5.00e-161	560.00
IUUC-Opr-071044	Ochotona princeps	48.01	5.00e-156	543.00
IUUC-Ont-071664	Oreochromis niloticus	45.91	5.00e-145	506.00
IUUC-Oan-073019	Ornithorhynchus anatinus	46.74	7.00e-153	532.00
IUUC-Ocu-074160	Oryctolagus cuniculus	48.01	1.00e-156	545.00
IUUC-Ola-087467	Oryzias latipes	47.58	6.00e-152	530.00
IUUC-Oga-088460	Otolemur garnettii	48.17	1.00e-156	545.00
IUUC-Oar-090198	Ovis aries	48.34	4.00e-158	550.00
IUUC-Ptr-090939	Pan troglodytes	48.17	4.00e-157	546.00
IUUC-Pan-092284	Papio anubis	48.17	4.00e-157	546.00
IUUC-Psi-093645	Pelodiscus sinensis	47.67	5.00e-157	546.00
IUUC-Pma-094364	Petromyzon marinus	52.77	2.00e-144	503.00
IUUC-Pno-095118	Phaeosphaeria nodorum	87.40	0.00e+00	1409.00
IUUC-Pfo-097145	Poecilia formosa	47.33	4.00e-152	530.00
IUUC-Pab-098088	Pongo abelii	48.17	8.00e-157	546.00
IUUC-Pca-100568	Procavia capensis	45.13	7.00e-141	493.00
IUUC-Pva-102354	Pteropus vampyrus	48.17	3.00e-156	543.00
IUUC-Pgr-103620	Puccinia graminis	77.92	0.00e+00	806.00
IUUC-Ptt-103806	Puccinia triticina	78.24	0.00e+00	691.00
IUUC-Pte-104016	Pyrenophora teres	100.00	0.00e+00	1511.00
IUUC-Rno-105318	Rattus norvegicus	48.17	6.00e-157	546.00
IUUC-Sce-106289	Saccharomyces cerevisiae	75.00	0.00e+00	915.00
IUUC-Sha-107482	Sarcophilus harrisii	47.60	1.00e-154	538.00
IUUC-Sja-107941	Schizosaccharomyces japonicus	66.50	0.00e+00	1042.00
IUUC-Spo-108171	Schizosaccharomyces pombe	63.25	0.00e+00	982.00
IUUC-Ssl-108514	Sclerotinia sclerotiorum	76.47	0.00e+00	1179.00
IUUC-Sar-113761	Sorex araneus	46.75	9.00e-152	529.00
IUUC-Sre-114929	Sporisorium reilianum	72.91	0.00e+00	894.00
IUUC-Ssc-115368	Sus scrofa	43.20	4.00e-143	500.00
IUUC-Tgu-117474	Taeniopygia guttata	49.48	5.00e-156	543.00
IUUC-Tru-118442	Takifugu rubripes	47.43	1.00e-155	541.00
IUUC-Tsy-119492	Tarsius syrichta	48.01	1.00e-154	538.00
IUUC-Tni-119993	Tetraodon nigroviridis	46.82	6.00e-149	520.00
IUUC-Tre-122203	Trichoderma reesei	71.98	0.00e+00	1102.00
IUUC-Tvi-122595	Trichoderma virens	71.77	0.00e+00	1129.00
IUUC-Tme-126897	Tuber melanosporum	70.96	0.00e+00	1102.00
IUUC-Tbe-127408	Tupaia belangeri	45.74	6.00e-139	487.00
IUUC-Ttr-128235	Tursiops truncatus	52.99	9.00e-148	516.00
IUUC-Uma-129332	Ustilago maydis	71.91	0.00e+00	852.00
IUUC-Vda-129753	Verticillium dahliae	71.92	0.00e+00	1092.00
IUUC-Vpa-130503	Vicugna pacos	51.67	7.00e-143	500.00
IUUC-Xtr-132859	Xenopus tropicalis	47.67	4.00e-156	543.00
IUUC-Xma-133797	Xiphophorus maculatus	52.37	3.00e-147	514.00
IUUC-Yli-134668	Yarrowia lipolytica	75.28	0.00e+00	954.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence