iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Cpo-021714

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAKN02030306

Gene Name

UBE2D2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCPOG00000008455.3	ENSCPOT00000008532.2	ENSCPOP00000007602.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E2/UBC	4.60e-56	188.4	5	139
UBD/UBC-like/UBD_UBC	9.60e-84	278.4	5	142

Active Site

Position(s)	Description	Evidence
85	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00388}

Domain Profile

E2/UBC

   S: 1    RlkkelkelekdppegisakpvdesdltewevlilGpedtpYeggvFkleiefpedYPfkPPkvkfltkifhPnvyenGkvClsilkee 89
           R++kel++l++dpp+++sa+pv + d+++w+++i+Gp+d+pY+ggvF l+i+ p+dYPfkPPkv f+t+i+hPn+++nG++Cl+il+  
   Q: 5    RIHKELNDLARDPPAQCSAGPVGD-DMFHWQATIMGPNDSPYQGGVFFLTIHSPTDYPFKPPKVAFTTRIYHPNINSNGNICLDILQ-- 90
           99**********************.9************************************************************9.. PP
   S: 90   ekWspalsvesvllsiqsllaepnpesplneeaaellkknreeykkkvr 138
           ++Wspal++++vllsi+sll++pnp++pl  e+a+++k++re+y++++r
   Q: 91   SQWSPALTISKVLLSICSLLCDPNPDDPLVPEIARIYKTDREKYNRIAR 139
           *********************************************9987 PP

UBD/UBC-like/UBD_UBC

   S: 1    rikkelkdllrdeeaqisadlvdddlfelratiagppdspyeggvffltiklptdypfkppkvafitkiyhpninsngsicldilrsqw 89
           ri+kel+dl+rd++aq+sa++v+dd+f+++ati+gp+dspy+ggvfflti+ ptdypfkppkvaf+t+iyhpninsng icldil+sqw
   Q: 5    RIHKELNDLARDPPAQCSAGPVGDDMFHWQATIMGPNDSPYQGGVFFLTIHSPTDYPFKPPKVAFTTRIYHPNINSNGNICLDILQSQW 93
           8**************************************************************************************** PP
   S: 90   saaltlskvllslcslladaepddplvaeiariyktdkekykriarewt 138
           s+alt+skvlls+csll+d++pddplv+eiariyktd+eky+riarewt
   Q: 94   SPALTISKVLLSICSLLCDPNPDDPLVPEIARIYKTDREKYNRIAREWT 142
           ************************************************8 PP

Organism

Cavia porcellus

Protein Sequence
(Fasta)

MALKRIHKEL NDLARDPPAQ CSAGPVGDDM FHWQATIMGP NDSPYQGGVF FLTIHSPTDY 60
PFKPPKVAFT TRIYHPNINS NGNICLDILQ SQWSPALTIS KVLLSICSLL CDPNPDDPLV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCTCTGA AAAGGATCCA CAAGGAATTG AATGATCTGG CACGGGACCC ACCAGCACAG 60
TGTTCAGCAG GTCCTGTTGG AGATGATATG TTCCATTGGC AAGCTACAAT AATGGGGCCA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR000608--UBQ-conjugat_E2
IPR023313--UBQ-conjugating_AS
IPR016135--UBQ-conjugating_enzyme/RWD

PROSITE

PS00183--UBIQUITIN_CONJUGAT_1
PS50127--UBIQUITIN_CONJUGAT_2

Pfam

PF00179--UQ_con

Gene Ontology

GO:0070062--C:extracellular exosome
GO:0043234--C:protein complex
GO:0000151--C:ubiquitin ligase complex
GO:0005524--F:ATP binding
GO:0061631--F:ubiquitin conjugating enzyme activity
GO:0051865--P:protein autoubiquitination
GO:0070936--P:protein K48-linked ubiquitination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000292	Aegilops tauschii	78.23	6.00e-68	249.00
IUUC-Aml-001778	Ailuropoda melanoleuca	97.86	7.00e-80	288.00
IUUC-Atr-002861	Amborella trichopoda	79.59	7.00e-69	252.00
IUUC-Aca-005236	Anolis carolinensis	97.96	2.00e-84	303.00
IUUC-Ago-007967	Ashbya gossypii	80.95	5.00e-71	259.00
IUUC-Ame-011831	Astyanax mexicanus	94.56	2.00e-81	293.00
IUUC-Bta-013158	Bos taurus	97.96	2.00e-84	303.00
IUUC-Bdi-014561	Brachypodium distachyon	78.91	2.00e-69	253.00
IUUC-Bra-016748	Brassica rapa	78.23	8.00e-69	254.00
IUUC-Cel-018362	Caenorhabditis elegans	91.84	8.00e-80	288.00
IUUC-Cja-019886	Callithrix jacchus	97.96	2.00e-84	303.00
IUUC-Cfa-020436	Canis familiaris	97.96	2.00e-84	303.00
IUUC-Csa-023148	Chlorocebus sabaeus	93.92	6.00e-80	288.00
IUUC-Cho-024987	Choloepus hoffmanni	87.07	2.00e-76	277.00
IUUC-Cin-025379	Ciona intestinalis	84.25	1.00e-74	271.00
IUUC-Csv-026311	Ciona savignyi	83.56	5.00e-71	259.00
IUUC-Dre-027758	Danio rerio	96.60	3.00e-83	300.00
IUUC-Dno-028952	Dasypus novemcinctus	97.86	3.00e-80	289.00
IUUC-Dme-031594	Drosophila melanogaster	92.52	1.00e-79	288.00
IUUC-Ete-032295	Echinops telfairi	97.84	2.00e-79	286.00
IUUC-Eca-033293	Equus caballus	97.84	1.00e-79	288.00
IUUC-Gga-040758	Gallus gallus	97.96	2.00e-84	303.00
IUUC-Gac-042231	Gasterosteus aculeatus	95.24	3.00e-82	296.00
IUUC-Ggo-045375	Gorilla gorilla	93.92	1.00e-80	291.00
IUUC-Hsa-045885	Homo sapiens	97.96	2.00e-84	303.00
IUUC-Hvu-047546	Hordeum vulgare	76.87	1.00e-67	248.00
IUUC-Itr-048882	Ictidomys tridecemlineatus	94.59	2.00e-80	290.00
IUUC-Kpa-049290	Komagataella pastoris	78.23	2.00e-68	250.00
IUUC-Lch-050109	Latimeria chalumnae	84.35	2.00e-75	273.00
IUUC-Lpe-051317	Leersia perrieri	80.95	1.00e-69	254.00
IUUC-Laf-053580	Loxodonta africana	97.86	5.00e-80	288.00
IUUC-Mcc-054673	Macaca mulatta	97.84	1.00e-79	288.00
IUUC-Mtr-058645	Medicago truncatula	79.59	1.00e-68	251.00
IUUC-Mdo-062962	Monodelphis domestica	97.96	2.00e-84	303.00
IUUC-Mmu-063518	Mus musculus	97.96	2.00e-84	303.00
IUUC-Mac-064668	Musa acuminata	78.91	3.00e-68	251.00
IUUC-Mpu-066604	Mustela putorius furo	93.84	2.00e-80	290.00
IUUC-Ont-071766	Oreochromis niloticus	96.60	2.00e-83	300.00
IUUC-Ocu-074315	Oryctolagus cuniculus	97.96	2.00e-84	303.00
IUUC-Oba-075063	Oryza barthii	80.95	4.00e-69	253.00
IUUC-Obr-076691	Oryza brachyantha	80.95	2.00e-69	254.00
IUUC-Ogl-077418	Oryza glaberrima	80.95	4.00e-69	253.00
IUUC-Ogu-078890	Oryza glumaepatula	80.95	4.00e-69	253.00
IUUC-Oin-079659	Oryza indica	79.59	2.00e-69	253.00
IUUC-Olo-080885	Oryza longistaminata	80.95	4.00e-69	253.00
IUUC-Ome-081920	Oryza meridionalis	80.95	4.00e-69	253.00
IUUC-Oni-082391	Oryza nivara	79.59	1.00e-69	256.00
IUUC-Opu-083548	Oryza punctata	80.95	4.00e-69	253.00
IUUC-Osa-085525	Oryza sativa	80.95	4.00e-69	253.00
IUUC-Ola-086331	Oryzias latipes	96.60	2.00e-83	300.00
IUUC-Ptr-090707	Pan troglodytes	97.96	2.00e-84	303.00
IUUC-Pan-092143	Papio anubis	97.96	2.00e-84	303.00
IUUC-Pma-094405	Petromyzon marinus	92.59	8.00e-74	268.00
IUUC-Ppa-095442	Physcomitrella patens	79.59	7.00e-69	252.00
IUUC-Pfo-096753	Poecilia formosa	96.60	2.00e-83	300.00
IUUC-Pab-097764	Pongo abelii	97.96	2.00e-84	303.00
IUUC-Pop-099853	Populus trichocarpa	79.59	7.00e-69	252.00
IUUC-Pca-100678	Procavia capensis	87.07	2.00e-76	277.00
IUUC-Pva-102770	Pteropus vampyrus	87.07	2.00e-76	277.00
IUUC-Sce-106153	Saccharomyces cerevisiae	80.56	1.00e-69	254.00
IUUC-Smo-108911	Selaginella moellendorffii	79.59	3.00e-68	250.00
IUUC-Sly-111055	Solanum lycopersicum	80.27	3.00e-69	253.00
IUUC-Sar-113302	Sorex araneus	97.84	2.00e-79	286.00
IUUC-Sbi-114840	Sorghum bicolor	79.59	2.00e-69	254.00
IUUC-Tru-118272	Takifugu rubripes	96.60	6.00e-83	298.00
IUUC-Tni-120056	Tetraodon nigroviridis	96.60	6.00e-83	298.00
IUUC-Tae-123340	Triticum aestivum	80.27	2.00e-70	257.00
IUUC-Tur-126518	Triticum urartu	78.23	3.00e-68	251.00
IUUC-Tbe-127609	Tupaia belangeri	97.44	6.00e-66	241.00
IUUC-Ttr-128363	Tursiops truncatus	87.07	2.00e-76	277.00
IUUC-Vpa-130446	Vicugna pacos	97.14	1.00e-78	285.00
IUUC-Vvi-131016	Vitis vinifera	78.91	3.00e-69	253.00
IUUC-Xtr-132329	Xenopus tropicalis	97.96	2.00e-84	303.00
IUUC-Xma-133829	Xiphophorus maculatus	96.60	2.00e-83	300.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence