iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Aml-002174

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ACTA01066369

Gene Name

USP38

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAMEG00000009698.1	ENSAMET00000010654.1	ENSAMEP00000010208.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	1.10e-81	274.7	491	995

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefsgyeq 89
           tGl NlgNtCYmNSv+Q+L++ +++r+++l+ + + +n         +l+k+lq+lf+ l +++++a++pr +++a +   + f+  +q
   Q: 491  TGLINLGNTCYMNSVIQALFMATDFRRQVLSLNLNGCN---------SLMKKLQHLFAFLAHTQREAYAPRVFFEASR--PPWFTARSQ 568
           7******************************5555554.........7***************************998..777****** PP
   S: 90   qDaqEflaflldqleeelkk...eknkpkeeeeeedkselsde........aeekkkkknkslisdlFqgqlksqikclecdnvssree 167
           qD++E+l+flld+l+ee k    +++++ +e+ + + +++++         ++  +   +k+li+++F+g+l+++i cl+c+++s++ e
   Q: 569  QDCSEYLRFLLDRLHEEEKIlkvQSSHKPSESLGCNVTSSQEVaskaavltESPCTSDGEKTLIEKMFGGKLRTHICCLNCRSTSQKVE 657
           *****************95566666666666666665555555778888877777778888**************************** PP
   S: 168  pfldlslpvpgkeetkke....................................................................... 185
            f+dlsl++  +++ +k+                                                                       
   Q: 658  AFTDLSLAFCPSSSIEKLsfqdaasspntqdgglmqanvpgpteepgvynpataafvcdsamnermlgspsdefrctentcvpnessri 746
           *********9999776669********************************************************************** PP
   S: 186  ................slqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefple 258
                           s++d+L+ f ++e l+g+n+yyce+c ++q+aek++++++ Pe+Lil L Rfs++++ ++r+ki ++v++pl 
   Q: 747  lvnkdvpqkpgggntpSVTDLLNYFLAPEILTGDNQYYCENCASLQNAEKTMQITEEPEYLILTLLRFSYDQKYHVRRKILDNVSLPLV 835
           ***************************************************************************************** PP
   S: 259  Ldlspfcts...............................peekqke.....kkkYeLiavvvHsG.slssGHYvayvkn......... 301
           L+l    t+                               +     e      + Y L+++vvHsG s++sGHY++y++n         
   Q: 836  LELPVKRTTsfsslseswsidvdftgisenlakklkpsgtE-----EtccsrLVPYLLSSIVVHSGvSSESGHYYSYARNitgtessyq 919
           99996555535556666666666666655555555544443.....0555559************************************ PP
   S: 302  ...................................ekgkWllfdDskVtevkeeevleetg....staYvlfYkrr 338
                                               +++W+lf+Ds+Vt ++ ++v++ t+    +taYvl+Yk++
   Q: 920  mchqsetralassqshllgrnslsavieqdlenkeMSKEWFLFNDSRVTFTSFQSVQKITSrfpkDTAYVLLYKKQ 995
           ***********9999999999999999988865544555*******************999************986 PP

Organism

Ailuropoda melanoleuca

Protein Sequence
(Fasta)

GGGGPSRCCA PSSPLPRDSP APRRDCCPPL LTPWPWPCSL ETMDKILEGL VSSSHPLPLK 60
RVIVRKVVES AEHWLDEAQC EAMFDLTTRL ILEGQDPFQR QVGHQVLEAY ARYHRPEFES 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGTGGCGGTG GTCCGTCCCG CTGCTGCGCT CCGAGTTCAC CTTTGCCGCG GGACTCTCCT 60
GCCCCACGTC GGGACTGTTG CCCTCCGCTC CTAACCCCCT GGCCCTGGCC TTGCAGTTTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR033840--USP38
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Apl-003435	Anas platyrhynchos	75.05	0.00e+00	1226.00
IUUC-Aca-004556	Anolis carolinensis	69.92	0.00e+00	1275.00
IUUC-Ame-010616	Astyanax mexicanus	61.21	0.00e+00	1212.00
IUUC-Bta-013544	Bos taurus	92.73	0.00e+00	1826.00
IUUC-Cja-018745	Callithrix jacchus	91.79	0.00e+00	1837.00
IUUC-Cfa-020434	Canis familiaris	91.40	0.00e+00	1788.00
IUUC-Cpo-021666	Cavia porcellus	91.01	0.00e+00	1775.00
IUUC-Csa-023965	Chlorocebus sabaeus	93.21	0.00e+00	1911.00
IUUC-Cho-024809	Choloepus hoffmanni	83.62	0.00e+00	1271.00
IUUC-Cin-025604	Ciona intestinalis	30.00	7.00e-40	157.00
IUUC-Csv-026333	Ciona savignyi	39.24	1.00e-32	132.00
IUUC-Dre-028338	Danio rerio	62.38	0.00e+00	1226.00
IUUC-Dno-029372	Dasypus novemcinctus	91.59	0.00e+00	1841.00
IUUC-Dor-030752	Dipodomys ordii	89.21	0.00e+00	1209.00
IUUC-Ete-032588	Echinops telfairi	79.74	0.00e+00	1135.00
IUUC-Eca-034416	Equus caballus	94.75	0.00e+00	1927.00
IUUC-Eeu-035132	Erinaceus europaeus	73.96	0.00e+00	1372.00
IUUC-Fca-036137	Felis catus	95.70	0.00e+00	1937.00
IUUC-Fal-037297	Ficedula albicollis	74.69	0.00e+00	1415.00
IUUC-Gmo-038727	Gadus morhua	65.33	0.00e+00	1007.00
IUUC-Gga-041091	Gallus gallus	72.82	0.00e+00	1364.00
IUUC-Gac-042082	Gasterosteus aculeatus	62.81	0.00e+00	1112.00
IUUC-Ggo-045376	Gorilla gorilla	88.21	0.00e+00	1743.00
IUUC-Hsa-046444	Homo sapiens	93.02	0.00e+00	1872.00
IUUC-Itr-047976	Ictidomys tridecemlineatus	92.20	0.00e+00	1870.00
IUUC-Lch-050500	Latimeria chalumnae	71.81	0.00e+00	1414.00
IUUC-Loc-052625	Lepisosteus oculatus	64.39	0.00e+00	1282.00
IUUC-Laf-053689	Loxodonta africana	92.70	0.00e+00	1877.00
IUUC-Mcc-055286	Macaca mulatta	93.31	0.00e+00	1875.00
IUUC-Mga-059905	Meleagris gallopavo	73.03	0.00e+00	1196.00
IUUC-Mmr-061397	Microcebus murinus	93.79	0.00e+00	1859.00
IUUC-Mdo-062833	Monodelphis domestica	85.03	0.00e+00	1747.00
IUUC-Mmu-063157	Mus musculus	89.58	0.00e+00	1785.00
IUUC-Mpu-066434	Mustela putorius furo	96.75	0.00e+00	1969.00
IUUC-Mlu-068178	Myotis lucifugus	92.66	0.00e+00	1823.00
IUUC-Nle-070153	Nomascus leucogenys	92.64	0.00e+00	1805.00
IUUC-Ont-072330	Oreochromis niloticus	62.38	0.00e+00	1218.00
IUUC-Oan-072709	Ornithorhynchus anatinus	80.66	0.00e+00	1273.00
IUUC-Ocu-074832	Oryctolagus cuniculus	93.21	0.00e+00	1843.00
IUUC-Ola-087003	Oryzias latipes	56.16	2.00e-49	188.00
IUUC-Oga-088517	Otolemur garnettii	89.07	0.00e+00	1771.00
IUUC-Oar-089472	Ovis aries	88.77	0.00e+00	1728.00
IUUC-Ptr-090996	Pan troglodytes	92.64	0.00e+00	1865.00
IUUC-Pan-091837	Papio anubis	92.28	0.00e+00	1880.00
IUUC-Psi-093236	Pelodiscus sinensis	76.34	0.00e+00	1163.00
IUUC-Pma-094349	Petromyzon marinus	52.94	0.00e+00	977.00
IUUC-Pfo-097193	Poecilia formosa	62.08	0.00e+00	1141.00
IUUC-Pab-098710	Pongo abelii	93.02	0.00e+00	1890.00
IUUC-Pca-100794	Procavia capensis	81.18	0.00e+00	1597.00
IUUC-Pva-102722	Pteropus vampyrus	92.74	0.00e+00	1881.00
IUUC-Rno-105743	Rattus norvegicus	88.15	0.00e+00	1745.00
IUUC-Sha-106563	Sarcophilus harrisii	83.72	0.00e+00	1407.00
IUUC-Sar-113533	Sorex araneus	77.46	0.00e+00	1531.00
IUUC-Ssc-116259	Sus scrofa	84.03	0.00e+00	1594.00
IUUC-Tgu-117475	Taeniopygia guttata	74.47	0.00e+00	1285.00
IUUC-Tru-118623	Takifugu rubripes	62.85	0.00e+00	1145.00
IUUC-Tsy-119250	Tarsius syrichta	91.64	0.00e+00	1444.00
IUUC-Tni-120441	Tetraodon nigroviridis	58.85	0.00e+00	1057.00
IUUC-Tbe-127936	Tupaia belangeri	80.11	0.00e+00	1510.00
IUUC-Ttr-128483	Tursiops truncatus	80.59	0.00e+00	1390.00
IUUC-Vpa-130303	Vicugna pacos	97.03	0.00e+00	1065.00
IUUC-Xtr-132773	Xenopus tropicalis	72.28	0.00e+00	1387.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence