iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mga-059855

UUCD1 version

UUC-MeG-00090

Ensembl Protein ID

ENSMGAP00000001308.2

UniProt Accession

G1MSK8; G1MSK8_MELGA

Protein Name

Uncharacterized protein

Gene Name

PRPF4

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMGAG00000001796.2	ENSMGAT00000001961.2	ENSMGAP00000001308.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.40e-37	125.8	419	457
UBD/Beta-Prp	1.80e-89	299.6	244	474

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvllk 37
           gH  ++++l+f ++  ++++Gs+D+t+kvWDlr+ +++ 
   Q: 419  GHLKEIYGLNFsPNgYHVATGSGDNTCKVWDLRQRKCIY 457
           7999********77799****************999975 PP

UBD/Beta-Prp

   S: 9    hksvitcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgk........ilvtgseDrtikvwdlstgkcvht 89
           ++ +++  +fsp+++llat++++g  k+w+v + +l+++l gh+  v a+ f+p++          l++++ D+ +k+w+l++ ++v  
   Q: 244  DDRPLSYCHFSPNSKLLATACWSGLCKLWSVPDCNLVHTLRGHSTNVGAIVFHPKATvsldkkdvNLASCAADGSVKLWSLESDEPVAD 332
           677888899*********************************************998888899999*********************** PP
   S: 90   lkghedsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgg 178
           ++gh+ +v  + ++psg +l ++  d   r+wdle ++++   ++gh++ v  +++h dg+l  +G+lD + r+Wdl+tg+++  l+g 
   Q: 333  IEGHSMRVARVMWHPSGRFLGTTCYDHSWRLWDLEAQEEIL-HQEGHSKGVYDIAFHTDGSLAGTGGLDAFGRVWDLRTGRCIMFLEG- 419
           *****************************************.********************************************99. PP
   S: 179  htdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfspn 233
           h + +y l+f++ng ++++gs d+t k+wdl++ +c++t  +h++ v+ v+f pn
   Q: 420  HLKEIYGLNFSPNGYHVATGSGDNTCKVWDLRQRKCIYTIPAHQNLVTGVKFEPN 474
           ****************************************************987 PP

Organism

Meleagris gallopavo

Protein Sequence
(Fasta)

RCTAGGEFGL SCPEDSRGTK RARSNPAKSK PSEEGDAPPA KRAPIFYGME EKERERLAKG 60
ESGLLGKEGM KAALEAGNIN ISSGEVFDLE DHMSERQAEV LAEFERRKRA RQINVSTDDS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CGCTGCACTG CGGGAGGGGA GTTTGGGCTC TCCTGCCCGG AAGCTCGGTG TGAGGAGTGG 60
GAGGAGCTTC GTGGCTTAAA GTTGGGAACA GAAATTCCAC AGACAAACAT CACCTGAAAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR014906--PRP4-like
IPR027295--Quinoprotein_ADH-like_fam
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF08799--PRP4
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00500--SFM
SM00320--WD40

Gene Ontology

GO:0015030--C:Cajal body
GO:0016607--C:nuclear speck
GO:0071001--C:U4/U6 snRNP

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000771	Aegilops tauschii	44.52	1.00e-101	362.00
IUUC-Aml-001737	Ailuropoda melanoleuca	90.82	0.00e+00	931.00
IUUC-Atr-002828	Amborella trichopoda	44.87	3.00e-107	381.00
IUUC-Apl-003723	Anas platyrhynchos	98.63	0.00e+00	1012.00
IUUC-Aca-004972	Anolis carolinensis	89.06	0.00e+00	918.00
IUUC-Aly-006531	Arabidopsis lyrata	42.70	9.00e-96	343.00
IUUC-Ath-007367	Arabidopsis thaliana	44.57	5.00e-111	394.00
IUUC-Ago-007893	Ashbya gossypii	34.51	4.00e-61	228.00
IUUC-Acl-008236	Aspergillus clavatus	39.24	2.00e-91	328.00
IUUC-Afl-008522	Aspergillus flavus	40.62	7.00e-100	357.00
IUUC-Afu-008904	Aspergillus fumigatus	39.52	5.00e-96	344.00
IUUC-Ani-009198	Aspergillus nidulans	40.62	4.00e-99	354.00
IUUC-Ang-009662	Aspergillus niger	42.29	7.00e-99	353.00
IUUC-Aor-009881	Aspergillus oryzae	40.62	8.00e-100	357.00
IUUC-Ate-010333	Aspergillus terreus	39.13	4.00e-89	321.00
IUUC-Ame-011697	Astyanax mexicanus	77.87	0.00e+00	813.00
IUUC-Bgr-012254	Blumeria graminis	39.19	3.00e-102	365.00
IUUC-Bta-012615	Bos taurus	88.27	0.00e+00	902.00
IUUC-Bci-013720	Botrytis cinerea	39.70	4.00e-101	361.00
IUUC-Bdi-014302	Brachypodium distachyon	45.33	3.00e-109	388.00
IUUC-Bol-015594	Brassica oleracea	44.57	3.00e-100	358.00
IUUC-Bra-017465	Brassica rapa	44.35	8.00e-101	360.00
IUUC-Cel-018632	Caenorhabditis elegans	44.51	5.00e-111	394.00
IUUC-Cja-019747	Callithrix jacchus	88.48	0.00e+00	937.00
IUUC-Cfa-020288	Canis familiaris	90.82	0.00e+00	932.00
IUUC-Cpo-021440	Cavia porcellus	89.24	0.00e+00	918.00
IUUC-Cre-022716	Chlamydomonas reinhardtii	45.94	6.00e-85	306.00
IUUC-Csa-023139	Chlorocebus sabaeus	93.09	0.00e+00	666.00
IUUC-Cho-024481	Choloepus hoffmanni	90.27	0.00e+00	826.00
IUUC-Cin-025106	Ciona intestinalis	59.62	1.00e-175	608.00
IUUC-Csv-026087	Ciona savignyi	58.99	2.00e-176	612.00
IUUC-Cgl-026538	Colletotrichum gloeosporioides	38.38	5.00e-94	338.00
IUUC-Cne-026793	Cryptococcus neoformans	41.72	3.00e-106	378.00
IUUC-Dre-028723	Danio rerio	78.26	0.00e+00	800.00
IUUC-Dno-029299	Dasypus novemcinctus	90.62	0.00e+00	931.00
IUUC-Dor-030345	Dipodomys ordii	61.71	1.00e-78	286.00
IUUC-Dse-031562	Dothistroma septosporum	37.71	1.00e-92	333.00
IUUC-Dme-031783	Drosophila melanogaster	57.58	1.00e-141	496.00
IUUC-Ete-032669	Echinops telfairi	88.20	0.00e+00	930.00
IUUC-Eca-033566	Equus caballus	90.82	0.00e+00	931.00
IUUC-Eeu-034524	Erinaceus europaeus	92.89	2.00e-140	492.00
IUUC-Fca-036215	Felis catus	90.82	0.00e+00	932.00
IUUC-Fal-037018	Ficedula albicollis	97.67	0.00e+00	839.00
IUUC-Fox-037936	Fusarium oxysporum	38.48	8.00e-89	320.00
IUUC-Fso-038366	Fusarium solani	39.15	5.00e-93	334.00
IUUC-Gmo-038966	Gadus morhua	67.23	3.00e-141	493.00
IUUC-Ggr-039942	Gaeumannomyces graminis	37.53	4.00e-86	311.00
IUUC-Gga-040797	Gallus gallus	99.40	0.00e+00	1007.00
IUUC-Gac-042598	Gasterosteus aculeatus	67.59	0.00e+00	676.00
IUUC-Gma-044220	Glycine max	44.89	2.00e-102	365.00
IUUC-Ggo-044682	Gorilla gorilla	90.44	0.00e+00	923.00
IUUC-Hsa-045804	Homo sapiens	88.29	0.00e+00	935.00
IUUC-Hvu-047567	Hordeum vulgare	44.55	2.00e-98	352.00
IUUC-Itr-047882	Ictidomys tridecemlineatus	88.08	0.00e+00	937.00
IUUC-Kpa-049369	Komagataella pastoris	32.88	4.00e-60	224.00
IUUC-Lch-050074	Latimeria chalumnae	78.42	0.00e+00	813.00
IUUC-Lpe-051333	Leersia perrieri	43.93	2.00e-99	355.00
IUUC-Loc-052164	Lepisosteus oculatus	79.02	0.00e+00	834.00
IUUC-Lma-053088	Leptosphaeria maculans	37.47	2.00e-86	312.00
IUUC-Laf-053460	Loxodonta africana	89.78	0.00e+00	934.00
IUUC-Mcc-055859	Macaca mulatta	90.82	0.00e+00	932.00
IUUC-Meu-056134	Macropus eugenii	89.19	0.00e+00	931.00
IUUC-Mor-057251	Magnaporthe oryzae	37.66	1.00e-87	316.00
IUUC-Mpo-057375	Magnaporthe poae	40.40	9.00e-54	202.00
IUUC-Mtr-057656	Medicago truncatula	43.83	3.00e-94	338.00
IUUC-Mla-059145	Melampsora laricipopulina	40.66	2.00e-102	365.00
IUUC-Mvi-060372	Microbotryum violaceum	43.15	1.00e-95	343.00
IUUC-Mmr-060826	Microcebus murinus	87.15	0.00e+00	936.00
IUUC-Mdo-062119	Monodelphis domestica	90.22	0.00e+00	923.00
IUUC-Mmu-063351	Mus musculus	90.42	0.00e+00	928.00
IUUC-Mac-064846	Musa acuminata	45.85	1.00e-98	352.00
IUUC-Mpu-066006	Mustela putorius furo	90.82	0.00e+00	932.00
IUUC-Mlu-067398	Myotis lucifugus	87.05	0.00e+00	931.00
IUUC-Nfi-068399	Neosartorya fischeri	39.52	1.00e-101	362.00
IUUC-Ncr-068711	Neurospora crassa	37.92	2.00e-94	339.00
IUUC-Nle-069982	Nomascus leucogenys	88.48	0.00e+00	937.00
IUUC-Opr-070596	Ochotona princeps	88.48	0.00e+00	939.00
IUUC-Ont-072374	Oreochromis niloticus	76.13	0.00e+00	767.00
IUUC-Oan-073166	Ornithorhynchus anatinus	90.79	0.00e+00	734.00
IUUC-Ocu-074371	Oryctolagus cuniculus	91.02	0.00e+00	934.00
IUUC-Oba-075083	Oryza barthii	43.31	5.00e-102	364.00
IUUC-Obr-076405	Oryza brachyantha	44.19	2.00e-98	352.00
IUUC-Ogl-077683	Oryza glaberrima	43.31	6.00e-102	364.00
IUUC-Ogu-078486	Oryza glumaepatula	43.54	1.00e-101	363.00
IUUC-Oin-079679	Oryza indica	43.51	9.00e-105	374.00
IUUC-Olo-080243	Oryza longistaminata	42.75	7.00e-90	323.00
IUUC-Ome-081230	Oryza meridionalis	43.31	1.00e-104	373.00
IUUC-Oni-082961	Oryza nivara	43.31	1.00e-104	372.00
IUUC-Opu-083189	Oryza punctata	43.17	3.00e-102	365.00
IUUC-Oru-084353	Oryza rufipogon	43.59	2.00e-102	365.00
IUUC-Osa-085458	Oryza sativa	43.31	1.00e-104	373.00
IUUC-Ola-086940	Oryzias latipes	73.81	0.00e+00	780.00
IUUC-Olu-087580	Ostreococcus lucimarinus	36.67	3.00e-66	245.00
IUUC-Oga-088703	Otolemur garnettii	83.52	0.00e+00	890.00
IUUC-Oar-089829	Ovis aries	87.50	0.00e+00	908.00
IUUC-Ptr-090838	Pan troglodytes	88.29	0.00e+00	935.00
IUUC-Pan-092261	Papio anubis	87.69	0.00e+00	931.00
IUUC-Psi-093020	Pelodiscus sinensis	91.96	0.00e+00	959.00
IUUC-Pno-094858	Phaeosphaeria nodorum	37.42	7.00e-81	294.00
IUUC-Ppa-095531	Physcomitrella patens	46.48	3.00e-117	414.00
IUUC-Pfo-096812	Poecilia formosa	69.28	0.00e+00	682.00
IUUC-Pab-097805	Pongo abelii	79.80	0.00e+00	803.00
IUUC-Pop-100051	Populus trichocarpa	46.12	2.00e-104	372.00
IUUC-Pca-100152	Procavia capensis	89.39	0.00e+00	932.00
IUUC-Ppe-101244	Prunus persica	46.92	4.00e-108	384.00
IUUC-Pva-102529	Pteropus vampyrus	85.41	0.00e+00	890.00
IUUC-Pgr-103550	Puccinia graminis	36.42	7.00e-103	367.00
IUUC-Ptt-103951	Puccinia triticina	34.69	1.00e-83	303.00
IUUC-Pte-104151	Pyrenophora teres	38.66	9.00e-82	296.00
IUUC-Pyt-104571	Pyrenophora triticirepentis	38.44	2.00e-82	299.00
IUUC-Rno-105747	Rattus norvegicus	90.22	0.00e+00	926.00
IUUC-Sce-106418	Saccharomyces cerevisiae	33.99	7.00e-70	257.00
IUUC-Sha-107334	Sarcophilus harrisii	89.90	0.00e+00	930.00
IUUC-Sja-107794	Schizosaccharomyces japonicus	35.98	3.00e-72	265.00
IUUC-Spo-108189	Schizosaccharomyces pombe	37.67	8.00e-84	303.00
IUUC-Ssl-108550	Sclerotinia sclerotiorum	38.84	3.00e-99	355.00
IUUC-Smo-109578	Selaginella moellendorffii	46.46	1.00e-112	399.00
IUUC-Sit-110102	Setaria italica	44.47	3.00e-104	371.00
IUUC-Sly-111668	Solanum lycopersicum	45.96	2.00e-107	382.00
IUUC-Stu-111928	Solanum tuberosum	45.74	2.00e-107	382.00
IUUC-Sar-113266	Sorex araneus	76.65	0.00e+00	764.00
IUUC-Sbi-114134	Sorghum bicolor	44.02	6.00e-104	370.00
IUUC-Sre-115114	Sporisorium reilianum	42.05	1.00e-106	379.00
IUUC-Ssc-115443	Sus scrofa	90.82	0.00e+00	931.00
IUUC-Tgu-117157	Taeniopygia guttata	97.37	0.00e+00	948.00
IUUC-Tru-118587	Takifugu rubripes	72.89	0.00e+00	750.00
IUUC-Tsy-119157	Tarsius syrichta	92.31	0.00e+00	741.00
IUUC-Tni-120427	Tetraodon nigroviridis	74.02	0.00e+00	764.00
IUUC-Tca-121368	Theobroma cacao	45.78	5.00e-109	387.00
IUUC-Tre-122074	Trichoderma reesei	38.56	2.00e-91	329.00
IUUC-Tvi-122349	Trichoderma virens	37.29	4.00e-89	321.00
IUUC-Tae-125651	Triticum aestivum	44.22	7.00e-104	370.00
IUUC-Tur-126532	Triticum urartu	43.60	1.00e-89	322.00
IUUC-Tme-126951	Tuber melanosporum	41.68	8.00e-105	373.00
IUUC-Tbe-128136	Tupaia belangeri	80.77	0.00e+00	828.00
IUUC-Ttr-129169	Tursiops truncatus	92.28	3.00e-157	547.00
IUUC-Uma-129399	Ustilago maydis	42.83	3.00e-103	368.00
IUUC-Vda-129842	Verticillium dahliae	38.84	1.00e-95	343.00
IUUC-Vpa-130440	Vicugna pacos	88.68	0.00e+00	937.00
IUUC-Vvi-131075	Vitis vinifera	47.40	7.00e-109	387.00
IUUC-Xtr-132713	Xenopus tropicalis	48.04	3.00e-105	374.00
IUUC-Xma-133002	Xiphophorus maculatus	80.78	2.00e-173	600.00
IUUC-Yli-134569	Yarrowia lipolytica	36.75	4.00e-79	288.00
IUUC-Zma-135799	Zea mays	42.74	1.00e-102	366.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence