iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Tme-127187

Ensembl Protein ID

CAZ80853

UniProt Accession

D5G8L0; D5G8L0_TUBMM

Genbank Protein ID

CAZ80853.1

Protein Name

Ubiquitin carboxyl-terminal hydrolase

Genbank Nucleotide ID

FN430047

Gene Name

GSTUM_00002995001

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
GSTUM_00002995001	CAZ80853	CAZ80853

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/UCH	1.90e-62	210.1	4	299

Active Site

Position(s)	Description	Evidence
89	Nucleophile	{ECO:0000256\|PIRSR:PIRSR038120-1}
164	Proton donor	{ECO:0000256\|PIRSR:PIRSR038120-1}

Domain Profile

DUB/UCH

   S: 7    ewleLesdPglftllvedfgvkrdiqveelysLdpenlglyqepvegllllFkinekressrksqvtsndlevvdediiktiffakqvigNsCatyAllsv 107
           +w ++esd+g+ft lv+++gvk++ q+ee+  Ld + l++ q pv+g+++lFk+   +++++   + ++     d  + ++iffa+q+i+N+Cat+A+lsv
   Q: 4    GWNTIESDAGVFTYLVDNLGVKNV-QFEEMIALDADYLNQ-QSPVYGVIFLFKYPVGQKKAD---EAVD--GQYDFAASENIFFANQTIQNACATQAILSV 97
           8***********************.************888.5************99888877...3344..67899999********************** PP
   S: 108  llncedklldlGttlsrlkestkaespenkalalgnqqvlecihnslariesrseperqdedneqytkeafhfvsyvningrlyeldglkpfPldlgkkke 208
           lln  d   dlG++l ++ke+t+a+ +e +++al+n++ ++ +hns+ar+ ++  +  +++++   +++++hf++y++ing lye dgl+p P+ +gk++e
   Q: 98   LLNRGDL--DLGDQLREFKEFTQAFPAELRGEALSNSELIRGVHNSFARSSPFIDEGTRAATE---DDDLYHFIAYTPINGILYEIDGLQPSPISHGKCTE 193
           ****999..******************************************999887765554...99******************************888 PP
   S: 209  teelkdklkvvraflerikllesdeirfnllaivadrrviktlrlnvlkidkeLlkLlkdieseeekieaqlddekekrkkfkiddirRtenydeficifi 309
           ++  ++ + v++    ri+ + + eirfnlla+v+d r+                       +e+    ++++ e+ekrk++  ++  R++n+++f  + +
   Q: 194  EQFPEKVIPVLQ---RRIERYPATEIRFNLLAMVQDLRIRA---------------------AEIGDV-ETVAREDEKRKMWIWENELRRHNFVGFAHEVL 269
           766665555555...9********************98732.....................233332.3467899************************* PP
   S: 310  kdlaregilrklveetisevrefgvnegrlak 341
           k     ++     +e i e ++      r++ 
   Q: 270  KRAVASKLRDGKYDEWIDEAKQKAK--DRMSE 299
           9999999999899999988776432..34444 PP

Organism

Tuber melanosporum

Protein Sequence
(Fasta)

MSGGWNTIES DAGVFTYLVD NLGVKNVQFE EMIALDADYL NQQSPVYGVI FLFKYPVGQK 60
KADEAVDGQY DFAASENIFF ANQTIQNACA TQAILSVLLN RGDLDLGDQL REFKEFTQAF 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CACAACACAG CACAGCACCC CACCCATCAA CCAACTCGAG GTTTTGATAT TTTTTTTCTT 60
CACCACAACT CACGGTGTAA ACTGAAGCTA ACTCGGATCT CCGTCTGTCT CTCACTAGAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0378--Hydrolase
KW-0645--Protease
KW-1185--Reference proteome
KW-0788--Thiol protease
KW-0833--Ubl conjugation pathway

Interpro

IPR001578--Peptidase_C12_UCH
IPR017390--Ubiquitinyl_hydrolase_UCH37

Pfam

PF01088--Peptidase_C12

PRINTS

PR00707--UBCTHYDRLASE

Gene Ontology

GO:0034399--C:nuclear periphery
GO:0031595--C:nuclear proteasome complex
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

KEGG

tml:GSTUM_00002995001

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000936	Aegilops tauschii	41.61	9.00e-66	241.00
IUUC-Aml-001866	Ailuropoda melanoleuca	40.59	4.00e-58	216.00
IUUC-Atr-002966	Amborella trichopoda	39.32	1.00e-59	221.00
IUUC-Apl-003306	Anas platyrhynchos	37.15	3.00e-51	193.00
IUUC-Aca-004763	Anolis carolinensis	40.59	7.00e-59	218.00
IUUC-Aly-005581	Arabidopsis lyrata	44.52	8.00e-65	238.00
IUUC-Ath-007283	Arabidopsis thaliana	43.55	3.00e-66	243.00
IUUC-Ago-007999	Ashbya gossypii	38.61	1.00e-44	171.00
IUUC-Acl-008231	Aspergillus clavatus	56.41	7.00e-95	338.00
IUUC-Afl-008557	Aspergillus flavus	61.76	2.00e-104	369.00
IUUC-Afu-008988	Aspergillus fumigatus	58.84	9.00e-99	351.00
IUUC-Ani-009420	Aspergillus nidulans	58.33	7.00e-97	345.00
IUUC-Ang-009859	Aspergillus niger	57.49	3.00e-93	332.00
IUUC-Aor-010145	Aspergillus oryzae	61.76	2.00e-104	369.00
IUUC-Ate-010347	Aspergillus terreus	56.71	3.00e-98	349.00
IUUC-Ame-010791	Astyanax mexicanus	38.92	1.00e-59	221.00
IUUC-Bgr-012298	Blumeria graminis	64.45	3.00e-109	385.00
IUUC-Bta-013251	Bos taurus	40.40	2.00e-58	217.00
IUUC-Bci-013786	Botrytis cinerea	68.91	3.00e-127	445.00
IUUC-Bdi-014132	Brachypodium distachyon	47.92	9.00e-63	231.00
IUUC-Bol-015611	Brassica oleracea	45.63	8.00e-65	238.00
IUUC-Bra-017769	Brassica rapa	44.66	1.00e-64	237.00
IUUC-Cel-018604	Caenorhabditis elegans	39.87	5.00e-54	202.00
IUUC-Cja-019768	Callithrix jacchus	37.16	2.00e-53	201.00
IUUC-Cfa-020207	Canis familiaris	40.59	4.00e-58	216.00
IUUC-Cpo-021925	Cavia porcellus	38.61	2.00e-51	194.00
IUUC-Cre-022919	Chlamydomonas reinhardtii	40.19	2.00e-55	207.00
IUUC-Csa-023958	Chlorocebus sabaeus	40.40	1.00e-58	218.00
IUUC-Cho-024928	Choloepus hoffmanni	54.32	7.00e-17	79.30
IUUC-Cin-025771	Ciona intestinalis	37.92	9.00e-56	208.00
IUUC-Csv-026149	Ciona savignyi	38.19	1.00e-55	208.00
IUUC-Cgl-026424	Colletotrichum gloeosporioides	56.27	5.00e-90	322.00
IUUC-Cne-026955	Cryptococcus neoformans	34.15	1.00e-45	174.00
IUUC-Cme-027104	Cyanidioschyzon merolae	35.12	6.00e-45	172.00
IUUC-Dre-027409	Danio rerio	38.32	1.00e-57	214.00
IUUC-Dno-028921	Dasypus novemcinctus	40.59	7.00e-58	215.00
IUUC-Dor-030891	Dipodomys ordii	35.00	2.00e-30	125.00
IUUC-Dse-031170	Dothistroma septosporum	61.49	1.00e-113	400.00
IUUC-Dme-031677	Drosophila melanogaster	40.24	4.00e-56	209.00
IUUC-Ete-032646	Echinops telfairi	39.00	5.00e-31	127.00
IUUC-Eca-033776	Equus caballus	40.07	1.00e-51	194.00
IUUC-Eeu-035305	Erinaceus europaeus	40.11	6.00e-32	129.00
IUUC-Fca-035846	Felis catus	37.27	1.00e-53	201.00
IUUC-Fal-037597	Ficedula albicollis	39.01	2.00e-52	196.00
IUUC-Fox-037670	Fusarium oxysporum	63.79	8.00e-102	361.00
IUUC-Fso-038243	Fusarium solani	62.79	7.00e-100	354.00
IUUC-Gmo-038499	Gadus morhua	38.08	2.00e-53	200.00
IUUC-Ggr-039975	Gaeumannomyces graminis	58.86	4.00e-97	345.00
IUUC-Gga-040904	Gallus gallus	41.25	3.00e-60	223.00
IUUC-Gac-042058	Gasterosteus aculeatus	41.58	1.00e-60	224.00
IUUC-Gma-043763	Glycine max	42.01	1.00e-65	241.00
IUUC-Ggo-044699	Gorilla gorilla	46.75	9.00e-58	214.00
IUUC-Hsa-046227	Homo sapiens	40.92	8.00e-59	218.00
IUUC-Hvu-047359	Hordeum vulgare	41.32	7.00e-65	238.00
IUUC-Itr-048989	Ictidomys tridecemlineatus	37.13	3.00e-53	200.00
IUUC-Lch-049829	Latimeria chalumnae	41.91	4.00e-60	223.00
IUUC-Lpe-050899	Leersia perrieri	50.22	5.00e-64	235.00
IUUC-Loc-052264	Lepisosteus oculatus	40.46	7.00e-58	215.00
IUUC-Lma-053110	Leptosphaeria maculans	66.44	1.00e-106	377.00
IUUC-Laf-053639	Loxodonta africana	40.59	4.00e-58	216.00
IUUC-Mcc-055506	Macaca mulatta	40.40	1.00e-58	218.00
IUUC-Meu-056267	Macropus eugenii	39.34	1.00e-37	149.00
IUUC-Mor-057001	Magnaporthe oryzae	59.26	2.00e-97	347.00
IUUC-Mpo-057608	Magnaporthe poae	61.62	3.00e-60	222.00
IUUC-Mtr-057731	Medicago truncatula	53.74	4.00e-68	249.00
IUUC-Mla-059016	Melampsora laricipopulina	42.16	7.00e-42	161.00
IUUC-Mga-060178	Meleagris gallopavo	40.07	2.00e-53	200.00
IUUC-Mvi-060353	Microbotryum violaceum	39.63	2.00e-57	214.00
IUUC-Mmr-060738	Microcebus murinus	40.59	2.00e-58	216.00
IUUC-Mdo-062266	Monodelphis domestica	47.37	1.00e-50	190.00
IUUC-Mmu-063619	Mus musculus	41.72	6.00e-59	218.00
IUUC-Mac-065301	Musa acuminata	43.22	2.00e-70	257.00
IUUC-Mpu-066058	Mustela putorius furo	40.59	3.00e-58	216.00
IUUC-Mlu-067292	Myotis lucifugus	41.06	6.00e-59	219.00
IUUC-Nfi-068275	Neosartorya fischeri	59.16	1.00e-106	377.00
IUUC-Ncr-068713	Neurospora crassa	61.47	9.00e-115	404.00
IUUC-Nle-069013	Nomascus leucogenys	40.40	4.00e-58	216.00
IUUC-Opr-070628	Ochotona princeps	35.45	4.00e-49	186.00
IUUC-Ont-072688	Oreochromis niloticus	40.46	4.00e-58	216.00
IUUC-Oan-073004	Ornithorhynchus anatinus	47.14	7.00e-51	191.00
IUUC-Ocu-074303	Oryctolagus cuniculus	41.25	8.00e-58	216.00
IUUC-Oba-075002	Oryza barthii	47.92	1.00e-63	234.00
IUUC-Obr-076392	Oryza brachyantha	48.33	2.00e-64	237.00
IUUC-Ogl-077271	Oryza glaberrima	47.92	1.00e-63	234.00
IUUC-Ogu-078493	Oryza glumaepatula	48.33	1.00e-64	238.00
IUUC-Oin-080084	Oryza indica	48.33	1.00e-64	238.00
IUUC-Olo-080803	Oryza longistaminata	40.90	4.00e-65	239.00
IUUC-Ome-081146	Oryza meridionalis	40.90	5.00e-65	239.00
IUUC-Oni-082146	Oryza nivara	48.33	1.00e-64	238.00
IUUC-Opu-083633	Oryza punctata	48.75	9.00e-65	238.00
IUUC-Oru-084789	Oryza rufipogon	48.33	1.00e-64	238.00
IUUC-Osa-086196	Oryza sativa	48.33	1.00e-64	238.00
IUUC-Ola-087126	Oryzias latipes	40.92	1.00e-59	221.00
IUUC-Olu-087665	Ostreococcus lucimarinus	41.45	2.00e-58	216.00
IUUC-Oga-089140	Otolemur garnettii	37.58	4.00e-54	203.00
IUUC-Oar-090296	Ovis aries	40.59	5.00e-57	212.00
IUUC-Ptr-090566	Pan troglodytes	40.92	8.00e-59	218.00
IUUC-Pan-092052	Papio anubis	40.40	1.00e-58	218.00
IUUC-Psi-093723	Pelodiscus sinensis	40.43	3.00e-53	199.00
IUUC-Pma-094568	Petromyzon marinus	45.65	5.00e-50	189.00
IUUC-Pno-095120	Phaeosphaeria nodorum	64.92	5.00e-112	395.00
IUUC-Ppa-095761	Physcomitrella patens	40.00	8.00e-63	231.00
IUUC-Pfo-096210	Poecilia formosa	40.59	4.00e-59	219.00
IUUC-Pab-098463	Pongo abelii	40.92	1.00e-58	218.00
IUUC-Pop-099109	Populus trichocarpa	41.72	2.00e-63	234.00
IUUC-Pca-100108	Procavia capensis	46.35	2.00e-54	203.00
IUUC-Ppe-101176	Prunus persica	41.72	1.00e-63	234.00
IUUC-Pva-102629	Pteropus vampyrus	47.62	9.00e-57	211.00
IUUC-Pgr-103419	Puccinia graminis	39.81	5.00e-52	196.00
IUUC-Pte-104207	Pyrenophora teres	66.67	8.00e-61	223.00
IUUC-Pyt-104471	Pyrenophora triticirepentis	63.46	7.00e-112	394.00
IUUC-Rno-105579	Rattus norvegicus	36.51	4.00e-49	186.00
IUUC-Sha-106894	Sarcophilus harrisii	42.31	2.00e-50	190.00
IUUC-Sja-107732	Schizosaccharomyces japonicus	49.84	8.00e-86	308.00
IUUC-Spo-108371	Schizosaccharomyces pombe	52.36	4.00e-85	305.00
IUUC-Ssl-108467	Sclerotinia sclerotiorum	68.73	1.00e-103	367.00
IUUC-Smo-109396	Selaginella moellendorffii	41.14	6.00e-62	228.00
IUUC-Sit-110630	Setaria italica	50.63	1.00e-66	244.00
IUUC-Sly-110972	Solanum lycopersicum	40.68	7.00e-62	228.00
IUUC-Stu-112185	Solanum tuberosum	42.06	3.00e-69	253.00
IUUC-Sar-113294	Sorex araneus	47.87	4.00e-46	176.00
IUUC-Sbi-113951	Sorghum bicolor	51.46	8.00e-67	244.00
IUUC-Ssc-115501	Sus scrofa	39.52	2.00e-53	200.00
IUUC-Tgu-117152	Taeniopygia guttata	39.01	2.00e-52	196.00
IUUC-Tru-118388	Takifugu rubripes	40.59	5.00e-60	222.00
IUUC-Tsy-119109	Tarsius syrichta	40.59	4.00e-58	216.00
IUUC-Tni-120048	Tetraodon nigroviridis	40.59	4.00e-60	222.00
IUUC-Tca-121750	Theobroma cacao	41.89	1.00e-68	251.00
IUUC-Tre-122130	Trichoderma reesei	61.26	2.00e-100	356.00
IUUC-Tvi-122284	Trichoderma virens	66.79	4.00e-101	358.00
IUUC-Tae-124082	Triticum aestivum	41.61	1.00e-65	241.00
IUUC-Tur-126366	Triticum urartu	42.92	3.00e-45	174.00
IUUC-Tbe-127705	Tupaia belangeri	39.34	1.00e-37	148.00
IUUC-Ttr-128867	Tursiops truncatus	41.95	2.00e-45	174.00
IUUC-Vda-129912	Verticillium dahliae	57.91	8.00e-97	344.00
IUUC-Vpa-130552	Vicugna pacos	46.92	2.00e-50	191.00
IUUC-Vvi-130881	Vitis vinifera	41.76	9.00e-63	231.00
IUUC-Xtr-131934	Xenopus tropicalis	39.40	1.00e-61	228.00
IUUC-Xma-133312	Xiphophorus maculatus	40.59	4.00e-59	219.00
IUUC-Yli-134487	Yarrowia lipolytica	45.57	2.00e-70	256.00
IUUC-Zma-135639	Zea mays	43.48	2.00e-57	214.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence