iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Oan-073240

UUCD1 version

UUC-OrA-00629

Ensembl Protein ID

ENSOANP00000002983.2

UniProt Accession

F7EZD3; F7EZD3_ORNAN

Protein Name

Uncharacterized protein

Gene Name

LOC100093152

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOANG00000001880.2	ENSOANT00000002984.2	ENSOANP00000002983.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	5.00e-92	309.1	10	296

Active Site

Position(s)	Description	Evidence
265	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00104}

Domain Profile

E3 activity/HECT

   S: 42   glflysendketlqpnpdsglknpehlklFeflGrllgkalqdgrlldlplsksfyklllgkklsledleevdpelykslkeikenaes 130
           g+f+y+e+ k  ++ np+s+    e +  F+++G++lg+a++++ +ld++++ ++y++l+gkk ++ dl++ +p ly+slk ++e+ e 
   Q: 10   GMFTYEESTKLFWF-NPSSF----ETEGQFTLIGIVLGLAIYNNCILDVHFPMVVYRKLMGKKGTFRDLADSHPVLYQSLKDLLEY-EG 92
           89999998877766.88887....789***********************************************************.66 PP
   S: 131  dieelgldltfsvseei.lgetkeeeLkpgGenipVtneNkeeYvklvveyrlkegikeqveafreGfneviple.llslFteeelell 217
           ++e+  + +tf++s++  +g+   ++Lk++G++ip+tneN++e+v+l+++y+l++++++q++afr+Gf+ v +++ l  lF++ee+ell
   Q: 93   SVEDD-MMITFQISQTDlFGNPMMYDLKENGDKIPITNENRKEFVSLYADYILNKSVEKQFKAFRRGFHMVTNESpLKYLFRPEEIELL 180
           77775.999**9665444******************************************************99934558********* PP
   S: 218  icGeeeidvedlkketkykggytedspaiqwFwevleefsseerkafLqFvTgssrlPlgGfaelkprlfvirkdasd.drlPssnTCf 305
           icG++++d+++l+++t+y+ggy +ds  i+ Fwe++++f++e+++ fLqF+Tg++r+P+gG+ +lk   ++i k++ d +rlP+s+TCf
   Q: 181  ICGSRNLDFQALEETTEYDGGYARDSLIIREFWEIVHSFTDEQKRLFLQFTTGTDRAPVGGLGKLK---MIIAKNGPDtERLPTSHTCF 266
           ******************************************************************...8888866666********** PP
   S: 306  nyLkLPeYsskeilkekLlyAieetkgFel 335
           n+L LPeYsske+lke+Ll Ai+++kgF++
   Q: 267  NVLLLPEYSSKEKLKERLLKAITYAKGFGM 296
           ****************************97 PP

Organism

Ornithorhynchus anatinus

Protein Sequence
(Fasta)

MSGLKLFLIG MFTYEESTKL FWFNPSSFET EGQFTLIGIV LGLAIYNNCI LDVHFPMVVY 60
RKLMGKKGTF RDLADSHPVL YQSLKDLLEY EGSVEDDMMI TFQISQTDLF GNPMMYDLKE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TGGGAATGCA ATTTATAATC CGTGCTTTAA ACGGCAACAG GTGCAGTGTT TCAAACCTCA 60
ACCTATTAGA CCTTTTCTGT ACCAGTTCTT CTGGGTGAAG TAAACAGCTT TCCAGTGACT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR000569--HECT_dom

PROSITE

PS50237--HECT

Pfam

PF00632--HECT

SMART

SM00119--HECTc

Gene Ontology

GO:0004842--F:ubiquitin-protein transferase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Cre-022790	Chlamydomonas reinhardtii	47.60	1.00e-71	262.00
IUUC-Cin-025643	Ciona intestinalis	59.38	6.00e-113	401.00
IUUC-Csv-026282	Ciona savignyi	60.76	1.00e-105	376.00
IUUC-Dme-032035	Drosophila melanogaster	58.13	7.00e-101	361.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence