iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Ocu-074588

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

SUMO-conjugating enzyme

Genbank Nucleotide ID

AAGW02008747

Gene Name

UBE2I

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOCUG00000029520.1	ENSOCUT00000033649.1	ENSOCUP00000026696.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E2/UBC	3.60e-41	140.2	8	137

Active Site

Position(s)	Description	Evidence
81	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00388}

Domain Profile

E2/UBC

   S: 1    RlkkelkelekdppegisakpvdesdltewevlilGpedtpYeggvFkleiefpedYPfkPPkvkfltkifhPnvyenGkvClsilkee 89
           Rl++e k+++kd+p g++a p+++ d     + ++     ++egg+Fkl++ f++dYP++PPk+kf+ ++fhPnvy++G+vClsil+e+
   Q: 8    RLAQERKAWRKDHPFGFVAVPTKNPD---GTMNLM-----NWEGGLFKLRMLFKDDYPSSPPKCKFEPPLFHPNVYPSGTVCLSILEED 88
           89*********************963...344445.....8************************************************ PP
   S: 90   ekWspalsvesvllsiqsllaepnpesplneeaaellkknreeykkkvr 138
           ++W+pa++++++ll+iq+ll+epn+++p+++ea++++++nr ey+k+vr
   Q: 89   KDWRPAITIKQILLGIQELLNEPNIQDPAQAEAYTIYCQNRVEYEKRVR 137
           ***********************************************98 PP

Organism

Oryctolagus cuniculus

Protein Sequence
(Fasta)

MSGIALSRLA QERKAWRKDH PFGFVAVPTK NPDGTMNLMN WEGGLFKLRM LFKDDYPSSP 60
PKCKFEPPLF HPNVYPSGTV CLSILEEDKD WRPAITIKQI LLGIQELLNE PNIQDPAQAE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ACTCCTTTTT GTTGGACATT TTCACTTCAA AAGAATCAAT ACTAGGGGGC TGCGCGCGGA 60
GCGGGCTCCG GAGGGAAGTC CCGAGACAAA GGGAAGCGCC GCCGCCGCCG CTCGGCCCCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR027230--Ubc9
IPR000608--UBQ-conjugat_E2
IPR023313--UBQ-conjugating_AS
IPR016135--UBQ-conjugating_enzyme/RWD

PROSITE

PS00183--UBIQUITIN_CONJUGAT_1
PS50127--UBIQUITIN_CONJUGAT_2

Pfam

PF00179--UQ_con

Gene Ontology

GO:0005829--C:cytosol
GO:0016605--C:PML body
GO:1990234--C:transferase complex
GO:0005524--F:ATP binding
GO:0003723--F:RNA binding
GO:0061656--F:SUMO conjugating enzyme activity
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0043123--P:positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:1903755--P:positive regulation of SUMO transferase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000510	Aegilops tauschii	64.42	8.00e-39	152.00
IUUC-Aml-002383	Ailuropoda melanoleuca	92.41	2.00e-82	297.00
IUUC-Atr-002982	Amborella trichopoda	59.62	3.00e-42	163.00
IUUC-Apl-003840	Anas platyrhynchos	92.41	3.00e-82	296.00
IUUC-Aca-004772	Anolis carolinensis	92.41	2.00e-82	297.00
IUUC-Aly-005652	Arabidopsis lyrata	61.04	1.00e-52	198.00
IUUC-Ath-007084	Arabidopsis thaliana	61.04	1.00e-52	198.00
IUUC-Ago-007998	Ashbya gossypii	53.85	1.00e-46	178.00
IUUC-Acl-008040	Aspergillus clavatus	58.55	3.00e-43	167.00
IUUC-Afl-008563	Aspergillus flavus	58.55	8.00e-43	165.00
IUUC-Afu-008873	Aspergillus fumigatus	59.57	1.00e-39	155.00
IUUC-Ani-009222	Aspergillus nidulans	57.89	9.00e-42	162.00
IUUC-Ang-009740	Aspergillus niger	62.77	8.00e-41	159.00
IUUC-Aor-010170	Aspergillus oryzae	59.21	3.00e-43	166.00
IUUC-Ate-010410	Aspergillus terreus	60.54	7.00e-43	166.00
IUUC-Ame-011711	Astyanax mexicanus	87.34	1.00e-79	288.00
IUUC-Bgr-012012	Blumeria graminis	51.32	4.00e-41	159.00
IUUC-Bta-013269	Bos taurus	92.41	2.00e-82	297.00
IUUC-Bci-013748	Botrytis cinerea	56.95	2.00e-39	154.00
IUUC-Bdi-014273	Brachypodium distachyon	58.97	4.00e-51	193.00
IUUC-Bol-016125	Brassica oleracea	60.90	7.00e-44	169.00
IUUC-Bra-017235	Brassica rapa	60.90	7.00e-44	169.00
IUUC-Cel-018448	Caenorhabditis elegans	71.15	2.00e-66	244.00
IUUC-Cja-019349	Callithrix jacchus	92.41	2.00e-82	297.00
IUUC-Cfa-021008	Canis familiaris	88.39	9.00e-55	205.00
IUUC-Cpo-021324	Cavia porcellus	92.41	2.00e-82	297.00
IUUC-Cre-022836	Chlamydomonas reinhardtii	56.05	4.00e-49	186.00
IUUC-Csa-024207	Chlorocebus sabaeus	92.41	2.00e-82	297.00
IUUC-Cin-025734	Ciona intestinalis	75.64	4.00e-69	253.00
IUUC-Csv-026049	Ciona savignyi	74.36	9.00e-68	248.00
IUUC-Cgl-026699	Colletotrichum gloeosporioides	58.22	7.00e-47	179.00
IUUC-Cne-027034	Cryptococcus neoformans	56.69	2.00e-52	197.00
IUUC-Cme-027203	Cyanidioschyzon merolae	54.84	9.00e-42	162.00
IUUC-Dre-027701	Danio rerio	91.72	2.00e-81	293.00
IUUC-Dno-030037	Dasypus novemcinctus	92.41	2.00e-82	297.00
IUUC-Dor-030622	Dipodomys ordii	90.51	5.00e-69	252.00
IUUC-Dse-031366	Dothistroma septosporum	57.62	4.00e-48	183.00
IUUC-Dme-031818	Drosophila melanogaster	78.48	2.00e-72	263.00
IUUC-Ete-032517	Echinops telfairi	91.24	2.00e-69	253.00
IUUC-Eca-033789	Equus caballus	92.41	2.00e-82	297.00
IUUC-Fca-035851	Felis catus	92.41	2.00e-82	297.00
IUUC-Fal-037177	Ficedula albicollis	92.41	3.00e-82	296.00
IUUC-Fox-037789	Fusarium oxysporum	57.89	4.00e-50	190.00
IUUC-Fso-038166	Fusarium solani	59.86	7.00e-50	189.00
IUUC-Gmo-039482	Gadus morhua	91.77	5.00e-82	295.00
IUUC-Ggr-039892	Gaeumannomyces graminis	60.00	2.00e-45	175.00
IUUC-Gga-041199	Gallus gallus	92.41	2.00e-82	297.00
IUUC-Gac-042250	Gasterosteus aculeatus	91.77	5.00e-82	295.00
IUUC-Gma-043827	Glycine max	61.15	9.00e-54	202.00
IUUC-Ggo-045530	Gorilla gorilla	92.41	2.00e-82	297.00
IUUC-Hsa-046248	Homo sapiens	92.41	2.00e-82	297.00
IUUC-Hvu-047363	Hordeum vulgare	57.14	3.00e-49	187.00
IUUC-Itr-048429	Ictidomys tridecemlineatus	92.41	2.00e-82	297.00
IUUC-Kpa-049362	Komagataella pastoris	54.49	3.00e-47	180.00
IUUC-Lch-050644	Latimeria chalumnae	89.87	8.00e-81	291.00
IUUC-Lpe-051643	Leersia perrieri	60.39	6.00e-52	196.00
IUUC-Loc-052357	Lepisosteus oculatus	91.77	7.00e-82	295.00
IUUC-Lma-053142	Leptosphaeria maculans	57.62	8.00e-50	189.00
IUUC-Laf-053577	Loxodonta africana	92.41	2.00e-82	297.00
IUUC-Mcc-054925	Macaca mulatta	92.41	2.00e-82	297.00
IUUC-Meu-056094	Macropus eugenii	75.91	4.00e-54	202.00
IUUC-Mor-057141	Magnaporthe oryzae	55.78	2.00e-48	184.00
IUUC-Mpo-057613	Magnaporthe poae	59.26	9.00e-45	172.00
IUUC-Mtr-058465	Medicago truncatula	61.94	8.00e-55	205.00
IUUC-Mla-059115	Melampsora laricipopulina	61.39	3.00e-55	206.00
IUUC-Mga-059384	Meleagris gallopavo	92.41	2.00e-82	297.00
IUUC-Mvi-060328	Microbotryum violaceum	57.32	3.00e-41	160.00
IUUC-Mmr-061541	Microcebus murinus	92.41	2.00e-82	297.00
IUUC-Mdo-062540	Monodelphis domestica	92.41	2.00e-82	297.00
IUUC-Mmu-063818	Mus musculus	92.41	2.00e-82	297.00
IUUC-Mac-065019	Musa acuminata	60.26	3.00e-52	197.00
IUUC-Mpu-065734	Mustela putorius furo	92.41	2.00e-82	297.00
IUUC-Mlu-067619	Myotis lucifugus	92.41	2.00e-82	297.00
IUUC-Nfi-068567	Neosartorya fischeri	58.55	4.00e-43	166.00
IUUC-Ncr-068897	Neurospora crassa	57.79	3.00e-49	187.00
IUUC-Nle-069541	Nomascus leucogenys	92.36	1.00e-81	294.00
IUUC-Ont-071585	Oreochromis niloticus	91.77	5.00e-82	295.00
IUUC-Oan-073178	Ornithorhynchus anatinus	84.21	4.00e-32	128.00
IUUC-Oba-075371	Oryza barthii	59.62	2.00e-51	194.00
IUUC-Obr-076199	Oryza brachyantha	59.62	1.00e-51	194.00
IUUC-Ogl-077506	Oryza glaberrima	59.62	2.00e-51	194.00
IUUC-Ogu-078474	Oryza glumaepatula	59.62	2.00e-51	194.00
IUUC-Oin-080036	Oryza indica	59.62	2.00e-51	194.00
IUUC-Olo-080940	Oryza longistaminata	53.25	2.00e-42	164.00
IUUC-Ome-081909	Oryza meridionalis	59.09	2.00e-50	191.00
IUUC-Oni-082340	Oryza nivara	59.62	2.00e-51	194.00
IUUC-Opu-083206	Oryza punctata	59.62	2.00e-51	194.00
IUUC-Oru-084239	Oryza rufipogon	59.62	2.00e-51	194.00
IUUC-Osa-086213	Oryza sativa	59.62	2.00e-51	194.00
IUUC-Ola-086314	Oryzias latipes	88.61	2.00e-80	290.00
IUUC-Olu-087900	Ostreococcus lucimarinus	50.32	3.00e-44	170.00
IUUC-Oga-088729	Otolemur garnettii	91.24	2.00e-69	254.00
IUUC-Oar-090221	Ovis aries	92.41	4.00e-82	296.00
IUUC-Ptr-090528	Pan troglodytes	92.41	2.00e-82	297.00
IUUC-Pan-092834	Papio anubis	92.41	2.00e-82	297.00
IUUC-Psi-093001	Pelodiscus sinensis	92.41	3.00e-82	296.00
IUUC-Pma-094539	Petromyzon marinus	89.87	4.00e-81	292.00
IUUC-Pno-094954	Phaeosphaeria nodorum	56.77	2.00e-48	184.00
IUUC-Ppa-095314	Physcomitrella patens	60.26	5.00e-52	196.00
IUUC-Pfo-097457	Poecilia formosa	91.14	1.00e-81	295.00
IUUC-Pab-098205	Pongo abelii	92.41	2.00e-82	297.00
IUUC-Pop-099063	Populus trichocarpa	61.04	1.00e-52	198.00
IUUC-Pca-100603	Procavia capensis	91.24	2.00e-69	254.00
IUUC-Ppe-101501	Prunus persica	61.54	2.00e-43	167.00
IUUC-Pva-103251	Pteropus vampyrus	76.64	8.00e-54	201.00
IUUC-Pte-104067	Pyrenophora teres	54.30	9.00e-48	182.00
IUUC-Pyt-104436	Pyrenophora triticirepentis	53.64	1.00e-47	181.00
IUUC-Rno-105794	Rattus norvegicus	92.41	2.00e-82	297.00
IUUC-Sce-106308	Saccharomyces cerevisiae	51.92	4.00e-46	176.00
IUUC-Sha-106997	Sarcophilus harrisii	83.12	4.00e-72	263.00
IUUC-Sja-108000	Schizosaccharomyces japonicus	62.82	2.00e-49	187.00
IUUC-Spo-108311	Schizosaccharomyces pombe	62.42	3.00e-49	187.00
IUUC-Smo-108685	Selaginella moellendorffii	62.18	3.00e-44	170.00
IUUC-Sit-109792	Setaria italica	60.39	1.00e-51	195.00
IUUC-Sly-111886	Solanum lycopersicum	60.26	2.00e-42	164.00
IUUC-Stu-111975	Solanum tuberosum	61.69	2.00e-47	181.00
IUUC-Sbi-114672	Sorghum bicolor	60.39	1.00e-51	195.00
IUUC-Sre-114957	Sporisorium reilianum	64.10	5.00e-58	216.00
IUUC-Ssc-116173	Sus scrofa	92.41	2.00e-82	297.00
IUUC-Tgu-116668	Taeniopygia guttata	92.41	3.00e-82	296.00
IUUC-Tru-118365	Takifugu rubripes	89.87	2.00e-80	290.00
IUUC-Tni-120455	Tetraodon nigroviridis	88.61	4.00e-80	289.00
IUUC-Tca-120956	Theobroma cacao	60.26	3.00e-51	194.00
IUUC-Tre-121927	Trichoderma reesei	58.50	4.00e-50	189.00
IUUC-Tvi-122363	Trichoderma virens	58.50	1.00e-49	188.00
IUUC-Tae-125311	Triticum aestivum	60.39	1.00e-51	194.00
IUUC-Tur-126625	Triticum urartu	59.74	4.00e-51	193.00
IUUC-Tme-126981	Tuber melanosporum	58.16	7.00e-39	152.00
IUUC-Ttr-128280	Tursiops truncatus	100.00	1.00e-47	181.00
IUUC-Uma-129582	Ustilago maydis	64.10	1.00e-57	214.00
IUUC-Vda-129845	Verticillium dahliae	61.22	5.00e-51	192.00
IUUC-Vpa-130242	Vicugna pacos	91.24	2.00e-69	254.00
IUUC-Vvi-130948	Vitis vinifera	59.62	1.00e-51	195.00
IUUC-Xtr-132540	Xenopus tropicalis	92.41	4.00e-82	296.00
IUUC-Xma-133010	Xiphophorus maculatus	91.14	1.00e-81	295.00
IUUC-Yli-134673	Yarrowia lipolytica	49.66	1.00e-43	168.00
IUUC-Zma-135055	Zea mays	60.39	8.00e-52	195.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence