iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Gac-041733

UUCD1 version

UUC-GaA-00796

Ensembl Protein ID

ENSGACP00000020386.1

UniProt Accession

G3PS00; G3PS00_GASAC

Protein Name

Coatomer subunit beta'

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSGACG00000015455.1	ENSGACT00000020425.1	ENSGACP00000020386.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.10e-33	114.2	183	224
UBD/Beta-Prp	4.40e-73	246.5	13	290

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf...sd.tllvsGsdDgtikvWDlrtgvllks 38
           gH+ +v+c+++    d ++l+sG+dD ++k+WD+   +++++
   Q: 183  GHEKGVNCIDYysgGDkPYLISGADDRQVKIWDYQNKTCVQT 224
           8*********9999778****************999988875 PP

UBD/Beta-Prp

   S: 8    hhksvitcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkgheds 96
           ++++++++v+ +p +++++++ ++g++ vw+ +t++l+++++ ++ +v+a kf  ++++ +tg++D+ i+v++++t + vh +++h+d+
   Q: 13   ARSDRVKSVDLHPTEPWMLASLYNGSVCVWNHETQTLVKTFEVCDLPVRASKFVARKNWVITGADDMQIRVFNYNTLERVHMFEAHSDY 101
           678999*********************************************************************************** PP
   S: 97   vlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdg.nllvsGslDrtvrlWdlktgkllrtltgghtdsvy 184
           +++++++p++ ++++ s+d  i++wd+e+++  +++++gh++ v+ +v++p++ n ++s+slDrt+++W+l + +   tl+g h++ v+
   Q: 102  IRCIAVHPTQPYILTSSDDMLIKLWDWEKKWSCSQVFEGHTHYVMQIVINPKDnNQFASASLDRTIKVWQLGSSSPNFTLEG-HEKGVN 189
           *******************************9999**********************************************9.****** PP
   S: 185  slsfdsng..kelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfspnderlvsgssDgsiriWdlrsgdllktlqlhnssvisva 271
           ++++ s g  ++l+sg++d++vk+wd+q+++cv+tl+gh +nv++v f+p+  ++++gs+Dg++riW + +  l +tl++  ++v++v+
   Q: 190  CIDYYSGGdkPYLISGADDRQVKIWDYQNKTCVQTLEGHAQNVSCVSFHPELPIIITGSEDGTVRIWHSSTYRLESTLNYGMERVWCVC 278
           ***8887777******************************************************************************* PP
   S: 272  vlsfgdnvlvlg 283
           +l+ ++nv +  
   Q: 279  GLRGSNNVALGY 290
           *99999987433 PP

Organism

Gasterosteus aculeatus

Functional Description
(View)

The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.

Protein Sequence
(Fasta)

MPLRLDIKRR LTARSDRVKS VDLHPTEPWM LASLYNGSVC VWNHETQTLV KTFEVCDLPV 60
RASKFVARKN WVITGADDMQ IRVFNYNTLE RVHMFEAHSD YIRCIAVHPT QPYILTSSDD 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AACAGCAGGA ACCCGATTGC CACTGCTCAC ATCTCATTTA TCGGATTTTA TTGTGACAAC 60
ACGGGGATAA ATCATGGTAA GAGACATTCG AAATAGTTCA TGCATGTTTT ATTTTGATAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0968--Cytoplasmic vesicle
KW-0931--ER-Golgi transport
KW-0333--Golgi apparatus
KW-0472--Membrane
KW-0653--Protein transport
KW-1185--Reference proteome
KW-0813--Transport
KW-0853--WD repeat

Interpro

IPR006692--Coatomer_WD-assoc_reg
IPR016453--COPB2
IPR020472--G-protein_beta_WD-40_rep
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom

PROSITE

PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF04053--Coatomer_WDAD
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0030663--C:COPI-coated vesicle membrane
GO:0000139--C:Golgi membrane
GO:0030117--C:membrane coat
GO:0005198--F:structural molecule activity
GO:0006886--P:intracellular protein transport
GO:0016192--P:vesicle-mediated transport

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000654	Aegilops tauschii	52.45	0.00e+00	924.00
IUUC-Aml-002154	Ailuropoda melanoleuca	89.40	0.00e+00	1669.00
IUUC-Atr-003090	Amborella trichopoda	57.72	0.00e+00	1053.00
IUUC-Apl-003976	Anas platyrhynchos	94.09	0.00e+00	1678.00
IUUC-Aca-004301	Anolis carolinensis	93.14	0.00e+00	1662.00
IUUC-Aly-006508	Arabidopsis lyrata	60.39	0.00e+00	1082.00
IUUC-Ath-007630	Arabidopsis thaliana	61.14	0.00e+00	1096.00
IUUC-Ago-007914	Ashbya gossypii	46.37	0.00e+00	754.00
IUUC-Acl-008237	Aspergillus clavatus	56.42	0.00e+00	963.00
IUUC-Afl-008535	Aspergillus flavus	53.60	0.00e+00	910.00
IUUC-Afu-008845	Aspergillus fumigatus	53.91	0.00e+00	935.00
IUUC-Ani-009135	Aspergillus nidulans	56.35	0.00e+00	911.00
IUUC-Ang-009654	Aspergillus niger	56.03	0.00e+00	853.00
IUUC-Aor-009939	Aspergillus oryzae	54.04	0.00e+00	969.00
IUUC-Ate-010355	Aspergillus terreus	54.76	0.00e+00	914.00
IUUC-Ame-010922	Astyanax mexicanus	87.12	0.00e+00	1536.00
IUUC-Bgr-012249	Blumeria graminis	53.88	0.00e+00	915.00
IUUC-Bta-013579	Bos taurus	95.23	0.00e+00	1437.00
IUUC-Bci-013866	Botrytis cinerea	55.07	0.00e+00	916.00
IUUC-Bdi-015046	Brachypodium distachyon	60.43	0.00e+00	1095.00
IUUC-Bol-016271	Brassica oleracea	60.63	0.00e+00	1098.00
IUUC-Bra-016617	Brassica rapa	60.77	0.00e+00	1066.00
IUUC-Cel-018387	Caenorhabditis elegans	64.78	0.00e+00	1165.00
IUUC-Cja-019145	Callithrix jacchus	89.64	0.00e+00	1667.00
IUUC-Cfa-020564	Canis familiaris	89.75	0.00e+00	1660.00
IUUC-Cpo-022201	Cavia porcellus	92.54	0.00e+00	1652.00
IUUC-Cre-022938	Chlamydomonas reinhardtii	59.20	0.00e+00	986.00
IUUC-Csa-023383	Chlorocebus sabaeus	94.36	0.00e+00	1145.00
IUUC-Cho-024454	Choloepus hoffmanni	88.44	0.00e+00	1359.00
IUUC-Cin-025681	Ciona intestinalis	77.84	0.00e+00	1358.00
IUUC-Csv-026012	Ciona savignyi	76.87	0.00e+00	1339.00
IUUC-Cgl-026649	Colletotrichum gloeosporioides	52.24	0.00e+00	835.00
IUUC-Cne-026986	Cryptococcus neoformans	50.85	0.00e+00	903.00
IUUC-Cme-027219	Cyanidioschyzon merolae	47.64	0.00e+00	849.00
IUUC-Dre-027846	Danio rerio	94.94	0.00e+00	1704.00
IUUC-Dor-030462	Dipodomys ordii	89.17	0.00e+00	1234.00
IUUC-Dse-031268	Dothistroma septosporum	54.72	0.00e+00	945.00
IUUC-Dme-031791	Drosophila melanogaster	72.27	0.00e+00	1261.00
IUUC-Ete-033166	Echinops telfairi	85.13	0.00e+00	985.00
IUUC-Eca-034180	Equus caballus	90.41	0.00e+00	1601.00
IUUC-Eeu-035086	Erinaceus europaeus	76.94	0.00e+00	783.00
IUUC-Fca-036265	Felis catus	89.07	0.00e+00	1670.00
IUUC-Fal-037202	Ficedula albicollis	93.89	0.00e+00	1621.00
IUUC-Fox-037711	Fusarium oxysporum	55.76	0.00e+00	880.00
IUUC-Fso-038268	Fusarium solani	55.88	0.00e+00	877.00
IUUC-Gmo-039046	Gadus morhua	96.33	0.00e+00	1709.00
IUUC-Ggr-039863	Gaeumannomyces graminis	55.24	0.00e+00	893.00
IUUC-Gga-041112	Gallus gallus	93.40	0.00e+00	1676.00
IUUC-Gma-044333	Glycine max	61.79	0.00e+00	1108.00
IUUC-Ggo-044984	Gorilla gorilla	89.42	0.00e+00	1660.00
IUUC-Hsa-046698	Homo sapiens	89.42	0.00e+00	1661.00
IUUC-Hvu-047669	Hordeum vulgare	70.06	3.00e-167	581.00
IUUC-Itr-048212	Ictidomys tridecemlineatus	89.83	0.00e+00	1664.00
IUUC-Kpa-049265	Komagataella pastoris	48.94	0.00e+00	855.00
IUUC-Lch-050473	Latimeria chalumnae	88.79	0.00e+00	1685.00
IUUC-Lpe-051579	Leersia perrieri	61.17	0.00e+00	1082.00
IUUC-Loc-052675	Lepisosteus oculatus	93.34	0.00e+00	1705.00
IUUC-Lma-053218	Leptosphaeria maculans	54.71	0.00e+00	918.00
IUUC-Laf-053757	Loxodonta africana	89.42	0.00e+00	1654.00
IUUC-Mcc-054859	Macaca mulatta	89.64	0.00e+00	1665.00
IUUC-Meu-056174	Macropus eugenii	89.21	0.00e+00	697.00
IUUC-Mor-057264	Magnaporthe oryzae	55.35	0.00e+00	881.00
IUUC-Mpo-057538	Magnaporthe poae	55.24	0.00e+00	905.00
IUUC-Mtr-058310	Medicago truncatula	61.67	0.00e+00	1113.00
IUUC-Mla-058937	Melampsora laricipopulina	53.21	0.00e+00	896.00
IUUC-Mga-059875	Meleagris gallopavo	93.40	0.00e+00	1670.00
IUUC-Mvi-060240	Microbotryum violaceum	51.06	0.00e+00	907.00
IUUC-Mmr-061261	Microcebus murinus	89.64	0.00e+00	1666.00
IUUC-Mdo-062076	Monodelphis domestica	92.11	0.00e+00	1672.00
IUUC-Mmu-063324	Mus musculus	88.56	0.00e+00	1663.00
IUUC-Mac-064636	Musa acuminata	58.93	0.00e+00	1077.00
IUUC-Mpu-065961	Mustela putorius furo	89.64	0.00e+00	1668.00
IUUC-Mlu-067059	Myotis lucifugus	92.19	0.00e+00	1604.00
IUUC-Nfi-068277	Neosartorya fischeri	53.63	0.00e+00	924.00
IUUC-Ncr-068659	Neurospora crassa	53.19	0.00e+00	909.00
IUUC-Nle-069034	Nomascus leucogenys	89.75	0.00e+00	1667.00
IUUC-Opr-070334	Ochotona princeps	94.42	0.00e+00	1470.00
IUUC-Ont-071563	Oreochromis niloticus	92.76	0.00e+00	1754.00
IUUC-Oan-073416	Ornithorhynchus anatinus	92.91	0.00e+00	1587.00
IUUC-Ocu-074522	Oryctolagus cuniculus	89.53	0.00e+00	1659.00
IUUC-Oba-075760	Oryza barthii	60.25	0.00e+00	1062.00
IUUC-Obr-076201	Oryza brachyantha	60.83	0.00e+00	1093.00
IUUC-Ogl-077450	Oryza glaberrima	61.48	0.00e+00	1090.00
IUUC-Ogu-078994	Oryza glumaepatula	60.25	0.00e+00	1061.00
IUUC-Oin-079856	Oryza indica	60.44	0.00e+00	1066.00
IUUC-Olo-080731	Oryza longistaminata	59.28	0.00e+00	1051.00
IUUC-Ome-081554	Oryza meridionalis	57.19	0.00e+00	988.00
IUUC-Oni-082324	Oryza nivara	60.25	0.00e+00	1062.00
IUUC-Opu-083400	Oryza punctata	58.35	0.00e+00	1051.00
IUUC-Oru-085196	Oryza rufipogon	58.95	0.00e+00	1033.00
IUUC-Osa-086026	Oryza sativa	61.48	0.00e+00	1093.00
IUUC-Ola-087245	Oryzias latipes	92.36	0.00e+00	1750.00
IUUC-Olu-087655	Ostreococcus lucimarinus	59.60	0.00e+00	1045.00
IUUC-Oga-088163	Otolemur garnettii	86.45	0.00e+00	1591.00
IUUC-Oar-089842	Ovis aries	92.78	0.00e+00	1657.00
IUUC-Ptr-090501	Pan troglodytes	89.44	0.00e+00	1662.00
IUUC-Pan-092011	Papio anubis	89.64	0.00e+00	1667.00
IUUC-Psi-093308	Pelodiscus sinensis	93.41	0.00e+00	1674.00
IUUC-Pma-094695	Petromyzon marinus	80.66	0.00e+00	1425.00
IUUC-Pno-094785	Phaeosphaeria nodorum	61.72	7.00e-111	394.00
IUUC-Ppa-095911	Physcomitrella patens	60.78	0.00e+00	1110.00
IUUC-Pfo-096587	Poecilia formosa	96.96	0.00e+00	1756.00
IUUC-Pab-097926	Pongo abelii	87.38	0.00e+00	1572.00
IUUC-Pop-099634	Populus trichocarpa	60.26	0.00e+00	1101.00
IUUC-Pca-100965	Procavia capensis	88.19	0.00e+00	1618.00
IUUC-Ppe-101470	Prunus persica	61.67	0.00e+00	1107.00
IUUC-Pva-102451	Pteropus vampyrus	88.27	0.00e+00	1225.00
IUUC-Pgr-103453	Puccinia graminis	52.83	0.00e+00	911.00
IUUC-Ptt-103868	Puccinia triticina	53.18	0.00e+00	909.00
IUUC-Pte-104274	Pyrenophora teres	55.64	0.00e+00	950.00
IUUC-Pyt-104794	Pyrenophora triticirepentis	54.98	0.00e+00	898.00
IUUC-Rno-105979	Rattus norvegicus	80.84	0.00e+00	1217.00
IUUC-Sce-106269	Saccharomyces cerevisiae	47.17	0.00e+00	783.00
IUUC-Sha-106905	Sarcophilus harrisii	92.10	0.00e+00	1669.00
IUUC-Sja-107838	Schizosaccharomyces japonicus	47.15	0.00e+00	822.00
IUUC-Spo-108299	Schizosaccharomyces pombe	46.08	0.00e+00	818.00
IUUC-Smo-108695	Selaginella moellendorffii	61.60	0.00e+00	1072.00
IUUC-Sit-110692	Setaria italica	62.15	0.00e+00	1091.00
IUUC-Sly-111525	Solanum lycopersicum	61.43	0.00e+00	1103.00
IUUC-Stu-112906	Solanum tuberosum	61.04	0.00e+00	977.00
IUUC-Sar-113472	Sorex araneus	87.22	0.00e+00	1117.00
IUUC-Sbi-114052	Sorghum bicolor	62.55	0.00e+00	1107.00
IUUC-Sre-115040	Sporisorium reilianum	51.77	0.00e+00	904.00
IUUC-Ssc-115593	Sus scrofa	89.53	0.00e+00	1663.00
IUUC-Tgu-117239	Taeniopygia guttata	93.85	0.00e+00	1676.00
IUUC-Tru-118025	Takifugu rubripes	96.51	0.00e+00	1743.00
IUUC-Tsy-118824	Tarsius syrichta	86.78	0.00e+00	1130.00
IUUC-Tni-120142	Tetraodon nigroviridis	97.52	0.00e+00	1738.00
IUUC-Tca-121613	Theobroma cacao	61.06	0.00e+00	1097.00
IUUC-Tre-122072	Trichoderma reesei	55.11	0.00e+00	921.00
IUUC-Tvi-122546	Trichoderma virens	54.38	0.00e+00	909.00
IUUC-Tae-125321	Triticum aestivum	59.76	0.00e+00	1077.00
IUUC-Tur-126283	Triticum urartu	53.31	0.00e+00	923.00
IUUC-Tme-127041	Tuber melanosporum	56.25	0.00e+00	975.00
IUUC-Tbe-127770	Tupaia belangeri	88.70	0.00e+00	1231.00
IUUC-Ttr-129294	Tursiops truncatus	89.64	0.00e+00	1662.00
IUUC-Uma-129351	Ustilago maydis	50.55	0.00e+00	895.00
IUUC-Vda-129716	Verticillium dahliae	54.85	0.00e+00	947.00
IUUC-Vpa-130037	Vicugna pacos	79.52	0.00e+00	818.00
IUUC-Vvi-131689	Vitis vinifera	61.50	0.00e+00	1096.00
IUUC-Xtr-132633	Xenopus tropicalis	91.23	0.00e+00	1645.00
IUUC-Xma-133347	Xiphophorus maculatus	92.47	0.00e+00	1761.00
IUUC-Yli-134455	Yarrowia lipolytica	50.38	0.00e+00	834.00
IUUC-Zma-135867	Zea mays	62.72	0.00e+00	1104.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence