iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mdo-062400

UUCD1 version

UUC-MoD-00913

Ensembl Protein ID

ENSMODP00000014695.3

UniProt Accession

F7FSS2; F7FSS2_MONDO

Protein Name

Uncharacterized protein

Gene Name

FBXW4

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMODG00000011732.3	ENSMODT00000014966.3	ENSMODP00000014695.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	3.70e-18	65.1	227	257

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    HtdsvtclafsdtllvsGsdDgtikvWDlrt 32
           H+ +v+c++ +++ +vsGs+D t kvW+l++
   Q: 227  HEQEVNCVDCQGGVIVSGSRDRTAKVWSLSS 257
           99*******95599**************865 PP

Organism

Monodelphis domestica

Protein Sequence
(Fasta)

MGRRGSPGPH GEAADADTDA EAEAGQAAAG AGAGAEEAEE VEAWPPGAGP GPPLWRLPEE 60
LLLLICSYLD SQALGRLGQV SRRLQRFTSR DLLWRPIARA CLNSGFTRHG TDLVTSIPVK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CTGGTTAAGG GCCCGGAGTC CCAGTGCTGG GGGGCGGGGG GGCGGTGATT GACAGGCGGC 60
GGCGACTGCG GCAGCGACGG CCCGGGCTCT AGCCGCCCCA TGTGACTCGG GCCAGGATGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR001810--F-box_dom
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom

PROSITE

PS50181--FBOX
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF12937--F-box-like
PF00400--WD40

SMART

SM00256--FBOX
SM00320--WD40

Gene Ontology

GO:0019005--C:SCF ubiquitin ligase complex
GO:0051216--P:cartilage development
GO:0042733--P:embryonic digit morphogenesis
GO:0002053--P:positive regulation of mesenchymal cell proliferation
GO:0031146--P:SCF-dependent proteasomal ubiquitin-dependent protein catabolic process

KEGG

mdo:100029445

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002129	Ailuropoda melanoleuca	77.54	9.00e-176	609.00
IUUC-Apl-003837	Anas platyrhynchos	81.93	4.00e-160	556.00
IUUC-Aca-004776	Anolis carolinensis	76.08	4.00e-158	550.00
IUUC-Ame-010651	Astyanax mexicanus	64.17	2.00e-118	418.00
IUUC-Bta-013495	Bos taurus	77.01	3.00e-166	577.00
IUUC-Cja-018901	Callithrix jacchus	77.24	3.00e-164	571.00
IUUC-Cfa-021251	Canis familiaris	77.01	5.00e-174	604.00
IUUC-Cpo-021750	Cavia porcellus	78.46	2.00e-156	544.00
IUUC-Csa-024026	Chlorocebus sabaeus	76.96	8.00e-172	597.00
IUUC-Cho-024496	Choloepus hoffmanni	59.62	4.00e-121	427.00
IUUC-Cin-025142	Ciona intestinalis	31.87	2.00e-26	112.00
IUUC-Csv-025883	Ciona savignyi	36.87	1.00e-67	250.00
IUUC-Dre-027447	Danio rerio	59.79	3.00e-136	478.00
IUUC-Dno-029572	Dasypus novemcinctus	65.58	6.00e-135	474.00
IUUC-Dor-030982	Dipodomys ordii	70.19	3.00e-152	531.00
IUUC-Ete-032917	Echinops telfairi	76.62	1.00e-153	535.00
IUUC-Eca-033969	Equus caballus	77.24	2.00e-164	572.00
IUUC-Eeu-034850	Erinaceus europaeus	71.27	2.00e-153	535.00
IUUC-Fca-036182	Felis catus	72.99	2.00e-159	555.00
IUUC-Fal-037391	Ficedula albicollis	76.47	2.00e-161	561.00
IUUC-Gmo-038632	Gadus morhua	58.85	2.00e-133	468.00
IUUC-Gga-040783	Gallus gallus	80.27	4.00e-173	600.00
IUUC-Gac-042314	Gasterosteus aculeatus	56.81	2.00e-113	402.00
IUUC-Ggo-044739	Gorilla gorilla	77.51	5.00e-172	597.00
IUUC-Hsa-046705	Homo sapiens	77.51	2.00e-164	571.00
IUUC-Itr-048014	Ictidomys tridecemlineatus	77.51	4.00e-137	480.00
IUUC-Loc-052397	Lepisosteus oculatus	71.61	6.00e-152	530.00
IUUC-Laf-054544	Loxodonta africana	77.06	9.00e-154	536.00
IUUC-Meu-056363	Macropus eugenii	71.91	1.00e-120	425.00
IUUC-Mga-059275	Meleagris gallopavo	81.76	7.00e-158	549.00
IUUC-Mmr-060906	Microcebus murinus	76.69	1.00e-170	592.00
IUUC-Mmu-063556	Mus musculus	76.69	7.00e-172	596.00
IUUC-Mpu-066500	Mustela putorius furo	77.27	4.00e-175	607.00
IUUC-Mlu-068074	Myotis lucifugus	77.23	2.00e-154	538.00
IUUC-Nle-069601	Nomascus leucogenys	77.51	4.00e-172	597.00
IUUC-Opr-070904	Ochotona princeps	70.21	2.00e-115	408.00
IUUC-Ont-072679	Oreochromis niloticus	56.92	2.00e-123	436.00
IUUC-Oan-073434	Ornithorhynchus anatinus	85.58	2.00e-100	357.00
IUUC-Ocu-074649	Oryctolagus cuniculus	77.78	5.00e-170	590.00
IUUC-Ola-087336	Oryzias latipes	51.70	3.00e-106	378.00
IUUC-Oga-088590	Otolemur garnettii	75.34	2.00e-160	558.00
IUUC-Oar-090178	Ovis aries	74.67	1.00e-153	536.00
IUUC-Pan-092881	Papio anubis	76.96	2.00e-171	595.00
IUUC-Pfo-096176	Poecilia formosa	57.22	2.00e-117	415.00
IUUC-Pab-098285	Pongo abelii	77.51	6.00e-172	597.00
IUUC-Pca-100888	Procavia capensis	72.73	2.00e-158	551.00
IUUC-Pva-102184	Pteropus vampyrus	65.85	1.00e-136	479.00
IUUC-Rno-105668	Rattus norvegicus	77.24	6.00e-173	600.00
IUUC-Sha-106629	Sarcophilus harrisii	98.13	0.00e+00	652.00
IUUC-Ssc-116183	Sus scrofa	78.34	5.00e-177	613.00
IUUC-Tgu-116630	Taeniopygia guttata	79.53	0.00e+00	635.00
IUUC-Tru-118761	Takifugu rubripes	53.68	1.00e-117	416.00
IUUC-Tni-120651	Tetraodon nigroviridis	53.47	4.00e-62	230.00
IUUC-Ttr-128582	Tursiops truncatus	77.27	3.00e-165	574.00
IUUC-Vpa-130431	Vicugna pacos	62.77	1.00e-80	293.00
IUUC-Xtr-132655	Xenopus tropicalis	72.43	1.00e-161	562.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence