iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Lch-049786

Ensembl Protein ID

ENSLACP00000020207.1

UniProt Accession

H3BE86; H3BE86_LATCH

Genbank Protein ID

ENSLACP00000020207

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AFYH01014002

Gene Name

KIF21B

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLACG00000017760.1	ENSLACT00000020347.1	ENSLACP00000020207.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	3.90e-26	90.2	1561	1595
UBD/Beta-Prp	1.00e-54	186.0	1318	1556

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sd.tllvsGsdDgtikvWDlrtgv 34
           H+d+v++la+ ++ ++l+s+++ g +kvW+++ ++
   Q: 1561 HKDWVCALAYvPGrPMLLSACRGGMLKVWNVDNFT 1595
           ***********999****************98765 PP

UBD/Beta-Prp

   S: 45   lrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfspsgdklvsGshdrtirvwdletg.qcle 130
           ++  +gh+++v +v+  ++  +l tgs+Drt k w+l tg+ ++tlkgh ++v+s++++   ++lv + + ++i+vwd++   +c++
   Q: 1318 VSMAEGHSKPVLCVDATDE--LLFTGSKDRTCKMWNLITGQEISTLKGHPNNVVSVKYCS-LSSLVFTVSTSYIKVWDIRDStKCVR 1401
           55569***********999..9*************************************9.88888888899*******96615666 PP
   S: 131  e.....................tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsvyslsfdsng...k 193
           +                       ++ ++ +n ++++p+g+ll +++  + vr+Wdl++++ + +l g h ++v +l+++++     
   Q: 1402 TltssgqvisgdacastttrtvSTAQGEHQINQIALNPSGSLLYAATG-NSVRIWDLNRMQAVGKLIG-HIGPVMCLTVNQTPsnhD 1486
           6*******************9955555668899999998888777665.68****************9.*********666555559 PP
   S: 194  elvsgsldgtvklwdlqtgecvrtlnght......dnvksvrfspnderlvsgssDgsiriWdlrsgdllkt 259
            +++gs+d +vk +++ +g++ ++  +h+      d + +++    ++ l sgs D+ i+ Wdl++++l+++
   Q: 1487 LVITGSKDHYVKRFEVAEGTIGNIGPAHNfepphyDGIECLAIQ--GDVLFSGSRDNGIKKWDLDQQELIQQ 1556
           99*******************99999999999999*******99..********************999876 PP

Organism

Latimeria chalumnae

Protein Sequence
(Fasta)

RIRPQLSREK IEGCHICTSV TPGEPQVLLG KDKAFTYDYV FDLEVHQEQI YTTCVQKLIE 60
GCFEGYNATV LAYGQTGAGK TYTMGTGFDV NLSAEEQGII PRAVHHLFQG IEERKRAAQE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AGGATCCGTC CACAGTTATC GAGGGAGAAG ATTGAAGGAT GCCATATTTG TACGTCTGTA 60
ACCCCTGGGG AGCCGCAGGT GCTGCTGGGA AAGGACAAGG CCTTCACGTA CGACTACGTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0505--Motor protein
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR011042--6-blade_b-propeller_TolB-like
IPR019821--Kinesin_motor_CS
IPR001752--Kinesin_motor_dom
IPR027417--P-loop_NTPase
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00411--KINESIN_MOTOR_1
PS50067--KINESIN_MOTOR_2
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00225--Kinesin
PF00400--WD40

PRINTS

PR00380--KINESINHEAVY

SMART

SM00129--KISc
SM00320--WD40

Gene Ontology

GO:0005524--F:ATP binding
GO:0003777--F:microtubule motor activity
GO:0007018--P:microtubule-based movement

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001391	Ailuropoda melanoleuca	56.47	0.00e+00	1110.00
IUUC-Apl-003204	Anas platyrhynchos	71.95	0.00e+00	1462.00
IUUC-Aca-004506	Anolis carolinensis	77.39	0.00e+00	1495.00
IUUC-Ame-011515	Astyanax mexicanus	74.44	0.00e+00	2282.00
IUUC-Bta-013485	Bos taurus	59.36	0.00e+00	1856.00
IUUC-Cel-018402	Caenorhabditis elegans	51.45	4.00e-145	509.00
IUUC-Cja-019385	Callithrix jacchus	54.89	0.00e+00	1061.00
IUUC-Cfa-020986	Canis familiaris	59.65	0.00e+00	1868.00
IUUC-Cpo-022297	Cavia porcellus	56.03	0.00e+00	1049.00
IUUC-Csa-023685	Chlorocebus sabaeus	55.78	0.00e+00	1086.00
IUUC-Cho-024531	Choloepus hoffmanni	71.39	2.00e-161	563.00
IUUC-Cin-025160	Ciona intestinalis	44.06	1.00e-82	300.00
IUUC-Csv-026158	Ciona savignyi	58.47	1.00e-175	610.00
IUUC-Dre-027839	Danio rerio	73.35	0.00e+00	2274.00
IUUC-Dno-029972	Dasypus novemcinctus	53.24	0.00e+00	991.00
IUUC-Dor-030673	Dipodomys ordii	80.20	0.00e+00	1499.00
IUUC-Ete-032705	Echinops telfairi	71.96	0.00e+00	771.00
IUUC-Eca-033518	Equus caballus	59.83	0.00e+00	1865.00
IUUC-Eeu-035338	Erinaceus europaeus	60.41	0.00e+00	960.00
IUUC-Fca-036197	Felis catus	59.84	0.00e+00	1867.00
IUUC-Fal-037044	Ficedula albicollis	80.48	0.00e+00	1603.00
IUUC-Gmo-039407	Gadus morhua	68.86	1.00e-177	617.00
IUUC-Gac-041626	Gasterosteus aculeatus	58.34	0.00e+00	1791.00
IUUC-Ggo-044457	Gorilla gorilla	56.08	0.00e+00	1090.00
IUUC-Hsa-046372	Homo sapiens	56.47	0.00e+00	1095.00
IUUC-Itr-049068	Ictidomys tridecemlineatus	79.47	0.00e+00	1381.00
IUUC-Loc-052703	Lepisosteus oculatus	79.15	0.00e+00	2444.00
IUUC-Laf-054018	Loxodonta africana	56.89	0.00e+00	1711.00
IUUC-Mcc-055558	Macaca mulatta	56.27	0.00e+00	1092.00
IUUC-Meu-056278	Macropus eugenii	74.08	0.00e+00	1048.00
IUUC-Mga-059283	Meleagris gallopavo	57.31	0.00e+00	1042.00
IUUC-Mmr-060773	Microcebus murinus	56.44	0.00e+00	1044.00
IUUC-Mdo-062688	Monodelphis domestica	56.39	0.00e+00	1093.00
IUUC-Mmu-063997	Mus musculus	55.43	0.00e+00	1053.00
IUUC-Mpu-066354	Mustela putorius furo	56.62	0.00e+00	1091.00
IUUC-Mlu-067599	Myotis lucifugus	55.95	0.00e+00	1087.00
IUUC-Nle-069477	Nomascus leucogenys	56.57	0.00e+00	1101.00
IUUC-Opr-070325	Ochotona princeps	77.51	0.00e+00	1446.00
IUUC-Ont-071851	Oreochromis niloticus	73.37	0.00e+00	2280.00
IUUC-Oan-073055	Ornithorhynchus anatinus	58.28	0.00e+00	1698.00
IUUC-Ocu-074302	Oryctolagus cuniculus	56.29	0.00e+00	1073.00
IUUC-Ola-086703	Oryzias latipes	72.27	0.00e+00	2253.00
IUUC-Oga-088799	Otolemur garnettii	56.05	0.00e+00	1077.00
IUUC-Oar-089629	Ovis aries	59.01	0.00e+00	1857.00
IUUC-Ptr-090535	Pan troglodytes	79.00	0.00e+00	1509.00
IUUC-Pan-092214	Papio anubis	55.78	0.00e+00	1085.00
IUUC-Psi-093757	Pelodiscus sinensis	54.29	0.00e+00	983.00
IUUC-Pfo-096827	Poecilia formosa	69.89	0.00e+00	2190.00
IUUC-Pab-097984	Pongo abelii	55.80	0.00e+00	1075.00
IUUC-Pca-101061	Procavia capensis	47.48	0.00e+00	990.00
IUUC-Pva-102306	Pteropus vampyrus	55.25	0.00e+00	1059.00
IUUC-Rno-105354	Rattus norvegicus	54.96	0.00e+00	1039.00
IUUC-Sha-106938	Sarcophilus harrisii	54.73	0.00e+00	1046.00
IUUC-Ssc-115810	Sus scrofa	54.66	0.00e+00	1078.00
IUUC-Tgu-117076	Taeniopygia guttata	54.55	0.00e+00	986.00
IUUC-Tru-117904	Takifugu rubripes	56.73	0.00e+00	1224.00
IUUC-Tsy-119020	Tarsius syrichta	56.23	0.00e+00	1086.00
IUUC-Tni-120813	Tetraodon nigroviridis	73.02	0.00e+00	803.00
IUUC-Ttr-128824	Tursiops truncatus	76.84	0.00e+00	1430.00
IUUC-Vpa-130675	Vicugna pacos	76.38	2.00e-163	570.00
IUUC-Xtr-131798	Xenopus tropicalis	62.67	0.00e+00	1841.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence