iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Sit-110245

Ensembl Protein ID

Si030199m

UniProt Accession

K3ZUB8; K3ZUB8_SETIT

Genbank Protein ID

KQL27019.1

Protein Name

E3 ubiquitin-protein ligase

Genbank Nucleotide ID

CM003529

Gene Name

LOC101770900; SETIT_030199mg

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
Si030199m.g	Si030199m	Si030199m

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	35.18	2.00e-38	157.00	IUUC-Dme-031700

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Setaria italica

Functional Description
(View)

E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.

Protein Sequence
(Fasta)

MVDGWKRCPK AVSERERERG GGSPLIRTPL PPLSSPSPWR HARAQPPPGD RILCPGILLR 60
SRLPSEDSVP IGIPMASVTY IDDSHAEVID PPKNEEMLDV TELVGEHIQH SPKPNVTSYG 120

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Nucleotide Sequence
(Fasta)

ATGGTCGATG GGTGGAAGAG GTGCCCCAAA GCTGGTAAAT GTGCGCTGTA ATTTGTCCCT 60
TGTTACCGCT TTGCTGAATG TTAAGCAAAT GTTAATTAGC AGAGTAAAAA AAGAAGAGTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR018121--7-in-absentia-prot_TRAF-dom
IPR001370--BIR_rpt
IPR004162--SINA-like
IPR008974--TRAF-like
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR013010--Znf_SIAH

PROSITE

PS50089--ZF_RING_2
PS51081--ZF_SIAH

Pfam

PF03145--Sina

Gene Ontology

GO:0005634--C:nucleus
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0007275--P:multicellular organism development
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Atr-003118	Amborella trichopoda	84.48	1.00e-149	521.00
IUUC-Aly-006522	Arabidopsis lyrata	83.59	4.00e-132	463.00
IUUC-Ath-007192	Arabidopsis thaliana	83.20	8.00e-132	462.00
IUUC-Bdi-014729	Brachypodium distachyon	80.99	2.00e-131	461.00
IUUC-Bol-015884	Brassica oleracea	80.14	2.00e-132	464.00
IUUC-Bra-016910	Brassica rapa	79.50	3.00e-133	466.00
IUUC-Cel-018320	Caenorhabditis elegans	33.72	8.00e-37	147.00
IUUC-Cin-025674	Ciona intestinalis	35.20	9.00e-42	162.00
IUUC-Csv-026233	Ciona savignyi	35.18	6.00e-42	163.00
IUUC-Dme-031700	Drosophila melanogaster	34.26	2.00e-36	145.00
IUUC-Gma-042926	Glycine max	85.10	6.00e-157	545.00
IUUC-Mtr-058422	Medicago truncatula	82.45	7.00e-152	528.00
IUUC-Mac-065670	Musa acuminata	80.83	9.00e-133	465.00
IUUC-Opr-070341	Ochotona princeps	24.84	7.00e-12	63.50
IUUC-Oan-073701	Ornithorhynchus anatinus	22.82	2.00e-11	62.00
IUUC-Oba-075789	Oryza barthii	95.03	9.00e-177	611.00
IUUC-Obr-076037	Oryza brachyantha	92.38	7.00e-179	619.00
IUUC-Ogl-077148	Oryza glaberrima	95.03	9.00e-177	611.00
IUUC-Ogu-078042	Oryza glumaepatula	93.87	7.00e-180	622.00
IUUC-Oin-079325	Oryza indica	95.36	3.00e-177	613.00
IUUC-Olo-080244	Oryza longistaminata	93.87	4.00e-180	624.00
IUUC-Oni-082163	Oryza nivara	95.03	9.00e-177	611.00
IUUC-Oru-084833	Oryza rufipogon	95.36	3.00e-177	613.00
IUUC-Osa-085316	Oryza sativa	95.36	3.00e-177	613.00
IUUC-Ppa-095212	Physcomitrella patens	83.33	3.00e-135	473.00
IUUC-Pop-100033	Populus trichocarpa	83.59	9.00e-132	462.00
IUUC-Ppe-101960	Prunus persica	83.59	3.00e-132	463.00
IUUC-Pva-103132	Pteropus vampyrus	23.90	2.00e-10	58.90
IUUC-Smo-109412	Selaginella moellendorffii	83.66	1.00e-133	468.00
IUUC-Sly-111259	Solanum lycopersicum	81.23	4.00e-131	459.00
IUUC-Stu-112474	Solanum tuberosum	84.26	9.00e-155	538.00
IUUC-Sbi-114035	Sorghum bicolor	98.68	0.00e+00	629.00
IUUC-Tsy-119548	Tarsius syrichta	27.35	3.00e-08	51.20
IUUC-Tca-121228	Theobroma cacao	89.42	1.00e-159	554.00
IUUC-Tur-126049	Triticum urartu	90.03	1.00e-170	591.00
IUUC-Vvi-131233	Vitis vinifera	78.87	1.00e-127	447.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence