iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mdo-062436

Ensembl Protein ID

ENSMODP00000002963.2

UniProt Accession

F7DZV2; F7DZV2_MONDO

Protein Name

Uncharacterized protein

Gene Name

RPTOR

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMODG00000002436.3	ENSMODT00000003023.3	ENSMODP00000002963.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	4.40e-14	52.2	1298	1326

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 4    dsvtclaf.sd.tllvsGsdDgtikvWDl 30
           + ++claf +  ++l++Gs+D  i v+++
   Q: 1298 GAISCLAFhPHwPHLAVGSNDYYISVYSV 1326
           679******888**************996 PP

Organism

Monodelphis domestica

Protein Sequence
(Fasta)

MESEMLQSPL LGLGEEDESD LTDWNLPLTF MKKRHCEKIE GSKSLAQSWR MKDRMKTVSV 60
ALVLCLNVGV DPPDVVKTTP CARLECWIDP LSMGPQKALE TIGANLQKQY ENWQPRARYK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GACTTTTTGG CGCTCCGTAG GTCGCTATGC ATTGTGGGCC TTAGCAATAT GGCGTCCCCC 60
TTGGTGTGCT AATGAGCGGA GTTTCTCAGT CTCTGAACGA GGAGGGGAAA TTCCTCAACC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR011989--ARM-like
IPR016024--ARM-type_fold
IPR029030--Caspase-like_dom
IPR004083--Raptor
IPR029347--Raptor_N
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom

PROSITE

PS50294--WD_REPEATS_REGION

Pfam

PF14538--Raptor_N
PF00400--WD40

SMART

SM01302--Raptor_N
SM00320--WD40

Gene Ontology

GO:0005737--C:cytoplasm
GO:0010494--C:cytoplasmic stress granule
GO:0005829--C:cytosol
GO:0005765--C:lysosomal membrane
GO:0005654--C:nucleoplasm
GO:0031931--C:TORC1 complex
GO:0030674--F:protein binding, bridging
GO:0030295--F:protein kinase activator activity
GO:0030291--F:protein serine/threonine kinase inhibitor activity
GO:0001030--F:RNA polymerase III type 1 promoter DNA binding
GO:0001031--F:RNA polymerase III type 2 promoter DNA binding
GO:0001032--F:RNA polymerase III type 3 promoter DNA binding
GO:0016049--P:cell growth
GO:0071230--P:cellular response to amino acid stimulus
GO:0009267--P:cellular response to starvation
GO:0030307--P:positive regulation of cell growth
GO:1900087--P:positive regulation of G1/S transition of mitotic cell cycle
GO:0033138--P:positive regulation of peptidyl-serine phosphorylation
GO:0010800--P:positive regulation of peptidyl-threonine phosphorylation
GO:0071902--P:positive regulation of protein serine/threonine kinase activity
GO:0032008--P:positive regulation of TOR signaling
GO:0045945--P:positive regulation of transcription from RNA polymerase III promoter
GO:0010506--P:regulation of autophagy
GO:0008361--P:regulation of cell size
GO:0031929--P:TOR signaling
GO:0038202--P:TORC1 signaling

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000354	Aegilops tauschii	57.30	0.00e+00	672.00
IUUC-Aml-001499	Ailuropoda melanoleuca	93.86	0.00e+00	2467.00
IUUC-Atr-002704	Amborella trichopoda	59.91	0.00e+00	732.00
IUUC-Apl-003540	Anas platyrhynchos	93.77	0.00e+00	2456.00
IUUC-Aca-004449	Anolis carolinensis	94.73	0.00e+00	1298.00
IUUC-Aly-006524	Arabidopsis lyrata	58.86	0.00e+00	759.00
IUUC-Ath-007242	Arabidopsis thaliana	59.11	0.00e+00	759.00
IUUC-Ago-007709	Ashbya gossypii	56.47	3.00e-117	417.00
IUUC-Acl-008215	Aspergillus clavatus	56.06	0.00e+00	766.00
IUUC-Afl-008401	Aspergillus flavus	53.26	0.00e+00	763.00
IUUC-Afu-008797	Aspergillus fumigatus	55.92	0.00e+00	768.00
IUUC-Ani-009268	Aspergillus nidulans	57.19	0.00e+00	759.00
IUUC-Ang-009608	Aspergillus niger	56.06	0.00e+00	757.00
IUUC-Aor-009894	Aspergillus oryzae	53.26	0.00e+00	762.00
IUUC-Ate-010357	Aspergillus terreus	55.79	0.00e+00	765.00
IUUC-Ame-011186	Astyanax mexicanus	93.42	0.00e+00	1327.00
IUUC-Bgr-012085	Blumeria graminis	52.65	0.00e+00	672.00
IUUC-Bta-013422	Bos taurus	94.61	0.00e+00	2499.00
IUUC-Bci-013736	Botrytis cinerea	52.57	0.00e+00	711.00
IUUC-Bdi-015042	Brachypodium distachyon	57.91	0.00e+00	699.00
IUUC-Bol-016048	Brassica oleracea	58.95	0.00e+00	760.00
IUUC-Bra-016961	Brassica rapa	57.01	0.00e+00	775.00
IUUC-Cel-018321	Caenorhabditis elegans	45.49	1.00e-100	362.00
IUUC-Cja-018939	Callithrix jacchus	93.19	0.00e+00	2465.00
IUUC-Cfa-020898	Canis familiaris	94.01	0.00e+00	2472.00
IUUC-Cpo-021514	Cavia porcellus	94.31	0.00e+00	2491.00
IUUC-Cre-022818	Chlamydomonas reinhardtii	63.95	3.00e-111	394.00
IUUC-Csa-023314	Chlorocebus sabaeus	93.79	0.00e+00	2494.00
IUUC-Cin-025701	Ciona intestinalis	72.49	0.00e+00	999.00
IUUC-Csv-026362	Ciona savignyi	71.68	0.00e+00	991.00
IUUC-Cgl-026561	Colletotrichum gloeosporioides	53.83	0.00e+00	679.00
IUUC-Cne-027009	Cryptococcus neoformans	48.01	0.00e+00	667.00
IUUC-Cme-027253	Cyanidioschyzon merolae	56.61	3.00e-137	484.00
IUUC-Dre-028485	Danio rerio	84.41	0.00e+00	2292.00
IUUC-Dno-029901	Dasypus novemcinctus	90.98	0.00e+00	2215.00
IUUC-Dor-030140	Dipodomys ordii	89.33	0.00e+00	2187.00
IUUC-Dse-031462	Dothistroma septosporum	49.86	0.00e+00	690.00
IUUC-Dme-031670	Drosophila melanogaster	64.67	0.00e+00	868.00
IUUC-Ete-032578	Echinops telfairi	68.05	0.00e+00	687.00
IUUC-Eca-034076	Equus caballus	94.54	0.00e+00	2503.00
IUUC-Eeu-035140	Erinaceus europaeus	93.08	0.00e+00	1167.00
IUUC-Fca-035651	Felis catus	94.01	0.00e+00	2477.00
IUUC-Fal-037244	Ficedula albicollis	93.34	0.00e+00	2394.00
IUUC-Fox-037742	Fusarium oxysporum	54.59	0.00e+00	681.00
IUUC-Fso-038369	Fusarium solani	55.67	0.00e+00	630.00
IUUC-Gmo-039007	Gadus morhua	77.84	0.00e+00	1737.00
IUUC-Ggr-039836	Gaeumannomyces graminis	52.81	0.00e+00	693.00
IUUC-Gga-041121	Gallus gallus	92.65	0.00e+00	2468.00
IUUC-Gac-041430	Gasterosteus aculeatus	86.05	0.00e+00	2263.00
IUUC-Gma-043160	Glycine max	60.44	0.00e+00	768.00
IUUC-Ggo-044934	Gorilla gorilla	98.56	0.00e+00	1417.00
IUUC-Hsa-045887	Homo sapiens	93.56	0.00e+00	2487.00
IUUC-Hvu-047823	Hordeum vulgare	58.18	0.00e+00	751.00
IUUC-Itr-048274	Ictidomys tridecemlineatus	95.45	0.00e+00	727.00
IUUC-Kpa-049399	Komagataella pastoris	59.26	6.00e-124	439.00
IUUC-Lch-050405	Latimeria chalumnae	90.20	0.00e+00	2413.00
IUUC-Lpe-050864	Leersia perrieri	64.90	1.00e-151	530.00
IUUC-Loc-051868	Lepisosteus oculatus	82.06	0.00e+00	2194.00
IUUC-Lma-052993	Leptosphaeria maculans	52.68	0.00e+00	753.00
IUUC-Laf-053339	Loxodonta africana	93.44	0.00e+00	1756.00
IUUC-Mcc-055591	Macaca mulatta	93.79	0.00e+00	2494.00
IUUC-Meu-056642	Macropus eugenii	85.73	0.00e+00	1171.00
IUUC-Mor-057204	Magnaporthe oryzae	53.53	0.00e+00	702.00
IUUC-Mpo-057532	Magnaporthe poae	53.45	0.00e+00	689.00
IUUC-Mtr-058553	Medicago truncatula	60.06	0.00e+00	754.00
IUUC-Mla-058907	Melampsora laricipopulina	44.94	7.00e-152	531.00
IUUC-Mga-059256	Meleagris gallopavo	94.25	0.00e+00	2472.00
IUUC-Mvi-060457	Microbotryum violaceum	49.52	0.00e+00	664.00
IUUC-Mmr-060874	Microcebus murinus	91.34	0.00e+00	2398.00
IUUC-Mmu-063264	Mus musculus	94.16	0.00e+00	2533.00
IUUC-Mac-065524	Musa acuminata	60.98	0.00e+00	719.00
IUUC-Mpu-065899	Mustela putorius furo	92.21	0.00e+00	2249.00
IUUC-Mlu-067344	Myotis lucifugus	90.24	0.00e+00	1812.00
IUUC-Nfi-068615	Neosartorya fischeri	57.64	0.00e+00	768.00
IUUC-Ncr-068744	Neurospora crassa	53.67	0.00e+00	674.00
IUUC-Nle-069014	Nomascus leucogenys	93.04	0.00e+00	2472.00
IUUC-Opr-070548	Ochotona princeps	87.37	0.00e+00	839.00
IUUC-Ont-072485	Oreochromis niloticus	86.61	0.00e+00	2285.00
IUUC-Oan-073253	Ornithorhynchus anatinus	96.14	0.00e+00	687.00
IUUC-Ocu-074290	Oryctolagus cuniculus	87.12	0.00e+00	723.00
IUUC-Oba-075130	Oryza barthii	56.53	0.00e+00	711.00
IUUC-Obr-076161	Oryza brachyantha	58.30	0.00e+00	749.00
IUUC-Ogl-077800	Oryza glaberrima	58.65	0.00e+00	746.00
IUUC-Ogu-078292	Oryza glumaepatula	65.41	3.00e-47	182.00
IUUC-Oin-080126	Oryza indica	53.01	0.00e+00	642.00
IUUC-Olo-080598	Oryza longistaminata	40.85	8.00e-35	141.00
IUUC-Ome-081293	Oryza meridionalis	56.60	2.00e-139	490.00
IUUC-Oni-082236	Oryza nivara	59.04	2.00e-83	304.00
IUUC-Opu-083423	Oryza punctata	57.59	0.00e+00	736.00
IUUC-Oru-085086	Oryza rufipogon	55.59	0.00e+00	681.00
IUUC-Osa-086012	Oryza sativa	57.89	0.00e+00	716.00
IUUC-Ola-086662	Oryzias latipes	85.04	0.00e+00	1959.00
IUUC-Olu-087760	Ostreococcus lucimarinus	58.08	0.00e+00	723.00
IUUC-Oga-088053	Otolemur garnettii	93.65	0.00e+00	2342.00
IUUC-Oar-089466	Ovis aries	90.78	0.00e+00	2468.00
IUUC-Ptr-090868	Pan troglodytes	92.89	0.00e+00	2474.00
IUUC-Pan-092259	Papio anubis	93.79	0.00e+00	2494.00
IUUC-Psi-093641	Pelodiscus sinensis	92.62	0.00e+00	2279.00
IUUC-Pno-094789	Phaeosphaeria nodorum	51.54	0.00e+00	714.00
IUUC-Ppa-095301	Physcomitrella patens	62.10	0.00e+00	764.00
IUUC-Pfo-096837	Poecilia formosa	85.30	0.00e+00	2290.00
IUUC-Pab-097545	Pongo abelii	90.35	0.00e+00	1189.00
IUUC-Pop-099209	Populus trichocarpa	62.77	0.00e+00	755.00
IUUC-Pca-100579	Procavia capensis	69.85	4.00e-177	615.00
IUUC-Ppe-101494	Prunus persica	58.40	0.00e+00	783.00
IUUC-Pva-103245	Pteropus vampyrus	84.24	0.00e+00	1782.00
IUUC-Pgr-103460	Puccinia graminis	47.12	8.00e-49	189.00
IUUC-Ptt-103797	Puccinia triticina	35.21	6.00e-65	243.00
IUUC-Pte-104367	Pyrenophora teres	53.45	0.00e+00	747.00
IUUC-Pyt-104771	Pyrenophora triticirepentis	50.72	0.00e+00	694.00
IUUC-Rno-104965	Rattus norvegicus	94.31	0.00e+00	2534.00
IUUC-Sce-106156	Saccharomyces cerevisiae	55.61	8.00e-119	422.00
IUUC-Sha-106474	Sarcophilus harrisii	94.32	0.00e+00	1966.00
IUUC-Sja-107888	Schizosaccharomyces japonicus	58.28	0.00e+00	773.00
IUUC-Spo-108057	Schizosaccharomyces pombe	57.08	0.00e+00	751.00
IUUC-Ssl-108423	Sclerotinia sclerotiorum	54.39	0.00e+00	715.00
IUUC-Smo-109363	Selaginella moellendorffii	57.55	0.00e+00	775.00
IUUC-Sit-109884	Setaria italica	57.80	0.00e+00	743.00
IUUC-Sly-110910	Solanum lycopersicum	57.25	0.00e+00	768.00
IUUC-Stu-112814	Solanum tuberosum	56.81	0.00e+00	760.00
IUUC-Sbi-113810	Sorghum bicolor	58.00	0.00e+00	742.00
IUUC-Sre-115168	Sporisorium reilianum	44.99	0.00e+00	681.00
IUUC-Ssc-115398	Sus scrofa	90.88	0.00e+00	1842.00
IUUC-Tgu-117361	Taeniopygia guttata	92.01	0.00e+00	2341.00
IUUC-Tsy-119587	Tarsius syrichta	99.29	0.00e+00	1158.00
IUUC-Tni-119757	Tetraodon nigroviridis	84.53	0.00e+00	2229.00
IUUC-Tca-121570	Theobroma cacao	62.77	0.00e+00	762.00
IUUC-Tre-122024	Trichoderma reesei	56.49	0.00e+00	641.00
IUUC-Tvi-122502	Trichoderma virens	55.99	0.00e+00	644.00
IUUC-Tae-125799	Triticum aestivum	58.18	0.00e+00	752.00
IUUC-Tme-127001	Tuber melanosporum	57.08	1.00e-153	537.00
IUUC-Ttr-129128	Tursiops truncatus	85.10	0.00e+00	2165.00
IUUC-Uma-129588	Ustilago maydis	45.17	0.00e+00	679.00
IUUC-Vda-129990	Verticillium dahliae	53.83	2.00e-179	623.00
IUUC-Vvi-131611	Vitis vinifera	58.28	0.00e+00	762.00
IUUC-Xtr-132727	Xenopus tropicalis	90.17	0.00e+00	2385.00
IUUC-Xma-133492	Xiphophorus maculatus	86.70	0.00e+00	2313.00
IUUC-Yli-134358	Yarrowia lipolytica	55.27	0.00e+00	697.00
IUUC-Zma-135723	Zea mays	57.62	0.00e+00	676.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence