iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Aca-005217

Ensembl Protein ID

ENSACAP00000007241.2

UniProt Accession

G1KGI5; G1KGI5_ANOCA

Protein Name

Uncharacterized protein

Gene Name

KLHL15

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSACAG00000007405.3	ENSACAT00000007396.3	ENSACAP00000007241.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_Other: BTB	2.50e-17	62.9	32	96

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_Other: BTB

   S: 2    DvilvvggeeffahkivLaasSsvFyalflmeleesksklmveikdvqpevfrallkFlYtgklde 67
           Dv+lv+++ +f+ahk+ La++S++F+ +f+ +++e++ ++++++k++ ++ f+++l+F+Y g++++
   Q: 32   DVTLVIEDHQFQAHKALLATQSDYFRIMFTADMRERD-QDKIHLKGLTATGFSHVLQFMYYGTIEL 96
           9***********************************9.************************9876 PP

Organism

Anolis carolinensis

Protein Sequence
(Fasta)

MAGDVEGFSS SIHDTSVSAG FRTLYEEGLL LDVTLVIEDH QFQAHKALLA TQSDYFRIMF 60
TADMRERDQD KIHLKGLTAT GFSHVLQFMY YGTIELSMTT VHEILQAAMY VQLIEVVKFC 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTGATTCATG GCAGGGGACG TGGAAGGATT TAGTTCCTCC ATCCATGACA CCAGTGTCTC 60
TGCTGGGTTC AGAACACTGT ATGAGGAAGG ATTGCTTCTT GACGTCACTC TTGTTATTGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0880--Kelch repeat
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR011705--BACK
IPR017096--BTB-kelch_protein
IPR000210--BTB/POZ_dom
IPR015915--Kelch-typ_b-propeller
IPR006652--Kelch_1
IPR030597--KLHL15
IPR011333--SKP1/BTB/POZ

PROSITE

PS50097--BTB

Pfam

PF07707--BACK
PF00651--BTB
PF01344--Kelch_1

SMART

SM00875--BACK
SM00225--BTB
SM00612--Kelch

Gene Ontology

GO:0031463--C:Cul3-RING ubiquitin ligase complex
GO:0005634--C:nucleus
GO:2000042--P:negative regulation of double-strand break repair via homologous recombination
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0071630--P:ubiquitin-dependent catabolism of misfolded proteins by nucleus-associated proteasome

KEGG

acs:100561950

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001418	Ailuropoda melanoleuca	93.71	0.00e+00	1108.00
IUUC-Apl-003970	Anas platyrhynchos	98.01	0.00e+00	1154.00
IUUC-Ame-011065	Astyanax mexicanus	86.59	0.00e+00	1077.00
IUUC-Bta-012443	Bos taurus	93.05	0.00e+00	1104.00
IUUC-Cja-019831	Callithrix jacchus	93.54	0.00e+00	1105.00
IUUC-Cfa-020941	Canis familiaris	93.87	0.00e+00	1110.00
IUUC-Cpo-021730	Cavia porcellus	93.38	0.00e+00	1107.00
IUUC-Csa-023247	Chlorocebus sabaeus	93.38	0.00e+00	1105.00
IUUC-Dre-028474	Danio rerio	86.92	0.00e+00	1083.00
IUUC-Dno-029411	Dasypus novemcinctus	94.21	0.00e+00	1110.00
IUUC-Dor-030576	Dipodomys ordii	93.21	0.00e+00	1104.00
IUUC-Ete-032327	Echinops telfairi	90.89	0.00e+00	1064.00
IUUC-Eca-033477	Equus caballus	93.71	0.00e+00	1109.00
IUUC-Fca-035546	Felis catus	93.71	0.00e+00	1110.00
IUUC-Fal-037370	Ficedula albicollis	98.01	0.00e+00	1154.00
IUUC-Gmo-038961	Gadus morhua	83.58	0.00e+00	994.00
IUUC-Gga-041049	Gallus gallus	97.85	0.00e+00	1152.00
IUUC-Gac-042003	Gasterosteus aculeatus	82.92	0.00e+00	999.00
IUUC-Ggo-044451	Gorilla gorilla	93.38	0.00e+00	1105.00
IUUC-Hsa-045874	Homo sapiens	93.38	0.00e+00	1105.00
IUUC-Itr-048357	Ictidomys tridecemlineatus	93.54	0.00e+00	1107.00
IUUC-Lch-049603	Latimeria chalumnae	90.68	1.00e-127	447.00
IUUC-Loc-052300	Lepisosteus oculatus	91.39	0.00e+00	1124.00
IUUC-Laf-054459	Loxodonta africana	94.37	0.00e+00	1112.00
IUUC-Mcc-054846	Macaca mulatta	93.38	0.00e+00	1105.00
IUUC-Meu-056797	Macropus eugenii	97.76	9.00e-115	407.00
IUUC-Mga-059446	Meleagris gallopavo	98.01	0.00e+00	1154.00
IUUC-Mmr-061125	Microcebus murinus	92.55	0.00e+00	1097.00
IUUC-Mdo-062947	Monodelphis domestica	95.03	0.00e+00	1110.00
IUUC-Mmu-063708	Mus musculus	93.87	0.00e+00	1109.00
IUUC-Mpu-066447	Mustela putorius furo	93.83	0.00e+00	1102.00
IUUC-Mlu-066999	Myotis lucifugus	90.11	0.00e+00	937.00
IUUC-Nle-069918	Nomascus leucogenys	93.38	0.00e+00	1105.00
IUUC-Ont-071446	Oreochromis niloticus	83.81	0.00e+00	980.00
IUUC-Oan-072872	Ornithorhynchus anatinus	93.54	0.00e+00	1142.00
IUUC-Ocu-073969	Oryctolagus cuniculus	94.07	0.00e+00	873.00
IUUC-Ola-087557	Oryzias latipes	82.32	2.00e-150	524.00
IUUC-Oga-088567	Otolemur garnettii	93.38	0.00e+00	1104.00
IUUC-Oar-089882	Ovis aries	93.21	0.00e+00	1105.00
IUUC-Ptr-091229	Pan troglodytes	93.38	0.00e+00	1077.00
IUUC-Pan-091977	Papio anubis	93.38	0.00e+00	1105.00
IUUC-Psi-093496	Pelodiscus sinensis	97.28	8.00e-159	553.00
IUUC-Pfo-096759	Poecilia formosa	82.90	0.00e+00	998.00
IUUC-Pab-098480	Pongo abelii	93.38	0.00e+00	1105.00
IUUC-Rno-105500	Rattus norvegicus	93.87	0.00e+00	1109.00
IUUC-Sha-106521	Sarcophilus harrisii	94.75	0.00e+00	1078.00
IUUC-Ssc-116372	Sus scrofa	93.54	0.00e+00	1109.00
IUUC-Tgu-116481	Taeniopygia guttata	98.01	0.00e+00	1154.00
IUUC-Tru-118542	Takifugu rubripes	81.29	0.00e+00	987.00
IUUC-Tsy-118848	Tarsius syrichta	92.73	1.00e-120	426.00
IUUC-Tni-119989	Tetraodon nigroviridis	81.73	0.00e+00	927.00
IUUC-Tbe-127485	Tupaia belangeri	93.71	0.00e+00	1107.00
IUUC-Ttr-129214	Tursiops truncatus	93.21	0.00e+00	1102.00
IUUC-Vpa-130261	Vicugna pacos	91.06	0.00e+00	1070.00
IUUC-Xtr-132092	Xenopus tropicalis	91.72	0.00e+00	1050.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence