iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Apl-003688

Ensembl Protein ID

ENSAPLP00000004132.1

UniProt Accession

U3IA61; U3IA61_ANAPL

Genbank Protein ID

ENSAPLP00000004132

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ADON01106795

Gene Name

ESR1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAPLG00000004585.1	ENSAPLT00000004741.1	ENSAPLP00000004132.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
UBD/Alpha-Helix/UMI	79.93	0.00e+00	802.00	IUUC-Hsa-046944

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Anas platyrhynchos

Protein Sequence
(Fasta)

MTMTLHTKTS GVTLLHQIQG TELETLSRPQ LKIPLERSLS DMYVESNKTG VFNYPEGATY 60
DFGTTAPVYG STTLSYAPTS ESFGSSSLAG FHSLNNVPPS PVVFLQTAPQ LSPFIHHHSQ 120

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Nucleotide Sequence
(Fasta)

TGTGCGTTTC CAGTGCTTAC CCTGCATTTG TTTGCATCCT CCTCCTTGCT GAGATCAGAG 60
GAATACCTGT GTAGTGCTGC TTTAACATGA TTTCTGCTGA ACCTCAGAAT AGGTTCTGGT 120

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Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0238--DNA-binding
KW-0479--Metal-binding
KW-0539--Nucleus
KW-0675--Receptor
KW-1185--Reference proteome
KW-0804--Transcription
KW-0805--Transcription regulation
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR000536--Nucl_hrmn_rcpt_lig-bd
IPR001723--Nuclear_hrmn_rcpt
IPR024178--Oest_rcpt/oest-rel_rcp
IPR001292--Oestr_rcpt
IPR001628--Znf_hrmn_rcpt
IPR013088--Znf_NHR/GATA

PROSITE

PS00031--NUCLEAR_REC_DBD_1
PS51030--NUCLEAR_REC_DBD_2

Pfam

PF00104--Hormone_recep
PF02159--Oest_recep
PF00105--zf-C4

PRINTS

PR00543--OESTROGENR
PR00398--STRDHORMONER
PR00047--STROIDFINGER

SMART

SM00430--HOLI
SM00399--ZnF_C4

Gene Ontology

GO:0005737--C:cytoplasm
GO:0000790--C:nuclear chromatin
GO:0005886--C:plasma membrane
GO:0035327--C:transcriptionally active chromatin
GO:0003682--F:chromatin binding
GO:0001046--F:core promoter sequence-specific DNA binding
GO:0034056--F:estrogen response element binding
GO:0000978--F:RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0038052--F:RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding
GO:0005496--F:steroid binding
GO:0001077--F:transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
GO:0008270--F:zinc ion binding
GO:0008209--P:androgen metabolic process
GO:0001547--P:antral ovarian follicle growth
GO:0071392--P:cellular response to estradiol stimulus
GO:0071391--P:cellular response to estrogen stimulus
GO:0002064--P:epithelial cell development
GO:0008584--P:male gonad development
GO:0043124--P:negative regulation of I-kappaB kinase/NF-kappaB signaling
GO:1903799--P:negative regulation of production of miRNAs involved in gene silencing by miRNA
GO:0043433--P:negative regulation of sequence-specific DNA binding transcription factor activity
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0048146--P:positive regulation of fibroblast proliferation
GO:0051091--P:positive regulation of sequence-specific DNA binding transcription factor activity
GO:0060527--P:prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis
GO:0060523--P:prostate epithelial cord elongation
GO:0071168--P:protein localization to chromatin
GO:0042981--P:regulation of apoptotic process
GO:0060687--P:regulation of branching involved in prostate gland morphogenesis
GO:0050727--P:regulation of inflammatory response
GO:0034121--P:regulation of toll-like receptor signaling pathway
GO:0060065--P:uterus development
GO:0060068--P:vagina development

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001925	Ailuropoda melanoleuca	87.21	0.00e+00	657.00
IUUC-Aca-005222	Anolis carolinensis	86.09	0.00e+00	894.00
IUUC-Ame-010731	Astyanax mexicanus	52.12	2.00e-131	462.00
IUUC-Bta-013112	Bos taurus	75.51	0.00e+00	766.00
IUUC-Cja-019408	Callithrix jacchus	80.86	0.00e+00	804.00
IUUC-Cfa-020694	Canis familiaris	77.37	0.00e+00	776.00
IUUC-Cpo-021426	Cavia porcellus	76.99	0.00e+00	766.00
IUUC-Csa-023736	Chlorocebus sabaeus	85.35	0.00e+00	712.00
IUUC-Dre-027698	Danio rerio	50.74	9.00e-133	466.00
IUUC-Dno-029477	Dasypus novemcinctus	85.27	0.00e+00	675.00
IUUC-Dor-030572	Dipodomys ordii	87.31	0.00e+00	634.00
IUUC-Ete-032849	Echinops telfairi	62.02	1.00e-167	582.00
IUUC-Eca-033605	Equus caballus	76.21	0.00e+00	759.00
IUUC-Eeu-034683	Erinaceus europaeus	84.11	4.00e-99	354.00
IUUC-Fca-035928	Felis catus	88.69	0.00e+00	659.00
IUUC-Fal-036754	Ficedula albicollis	97.37	0.00e+00	1010.00
IUUC-Gmo-038872	Gadus morhua	54.39	1.00e-105	376.00
IUUC-Gga-040988	Gallus gallus	98.87	0.00e+00	1004.00
IUUC-Gac-042015	Gasterosteus aculeatus	62.85	3.00e-120	425.00
IUUC-Ggo-044749	Gorilla gorilla	80.67	0.00e+00	800.00
IUUC-Hsa-046944	Homo sapiens	79.93	0.00e+00	791.00
IUUC-Itr-048863	Ictidomys tridecemlineatus	80.30	0.00e+00	802.00
IUUC-Loc-052414	Lepisosteus oculatus	60.18	0.00e+00	652.00
IUUC-Mcc-054781	Macaca mulatta	80.67	0.00e+00	800.00
IUUC-Meu-056232	Macropus eugenii	83.49	0.00e+00	836.00
IUUC-Mga-059319	Meleagris gallopavo	98.50	0.00e+00	1002.00
IUUC-Mmr-061636	Microcebus murinus	73.44	6.00e-140	490.00
IUUC-Mdo-062661	Monodelphis domestica	85.74	0.00e+00	862.00
IUUC-Mmu-063330	Mus musculus	78.97	0.00e+00	791.00
IUUC-Mpu-065757	Mustela putorius furo	78.25	0.00e+00	801.00
IUUC-Mlu-067712	Myotis lucifugus	80.69	0.00e+00	707.00
IUUC-Nle-069283	Nomascus leucogenys	79.37	0.00e+00	771.00
IUUC-Opr-070391	Ochotona princeps	79.10	0.00e+00	811.00
IUUC-Ont-071369	Oreochromis niloticus	51.03	2.00e-115	409.00
IUUC-Oan-073734	Ornithorhynchus anatinus	72.28	5.00e-107	380.00
IUUC-Ocu-074292	Oryctolagus cuniculus	80.59	0.00e+00	804.00
IUUC-Oba-075103	Oryza barthii	26.92	1.10e-02	34.70
IUUC-Ogu-079042	Oryza glumaepatula	26.92	3.00e-03	36.60
IUUC-Olo-080944	Oryza longistaminata	26.92	4.00e-03	34.30
IUUC-Oni-082560	Oryza nivara	26.92	9.00e-03	34.70
IUUC-Ola-087052	Oryzias latipes	52.14	1.00e-124	440.00
IUUC-Oga-088586	Otolemur garnettii	79.48	0.00e+00	782.00
IUUC-Oar-090156	Ovis aries	80.52	0.00e+00	685.00
IUUC-Ptr-091321	Pan troglodytes	80.67	0.00e+00	800.00
IUUC-Pan-092851	Papio anubis	80.48	0.00e+00	798.00
IUUC-Psi-093434	Pelodiscus sinensis	89.85	0.00e+00	948.00
IUUC-Pfo-097379	Poecilia formosa	56.99	3.00e-132	465.00
IUUC-Pab-097735	Pongo abelii	80.48	0.00e+00	798.00
IUUC-Pva-102125	Pteropus vampyrus	79.33	0.00e+00	798.00
IUUC-Rno-106121	Rattus norvegicus	78.82	0.00e+00	792.00
IUUC-Sha-107547	Sarcophilus harrisii	85.55	0.00e+00	857.00
IUUC-Sar-113650	Sorex araneus	68.35	2.00e-157	548.00
IUUC-Tgu-117175	Taeniopygia guttata	96.99	0.00e+00	1009.00
IUUC-Tru-117545	Takifugu rubripes	52.11	2.00e-134	473.00
IUUC-Tsy-119586	Tarsius syrichta	69.20	0.00e+00	667.00
IUUC-Tni-120121	Tetraodon nigroviridis	51.67	7.00e-137	480.00
IUUC-Tbe-127548	Tupaia belangeri	76.17	6.00e-154	537.00
IUUC-Ttr-128374	Tursiops truncatus	71.93	0.00e+00	687.00
IUUC-Vpa-130464	Vicugna pacos	74.59	1.00e-139	489.00
IUUC-Xtr-132171	Xenopus tropicalis	79.17	0.00e+00	761.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence