iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ggo-044712

Ensembl Protein ID

ENSGGOP00000014352.2

UniProt Accession

G3RFI6; G3RFI6_GORGO

Protein Name

Uncharacterized protein

Gene Name

PHF8

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSGGOG00000014703.2	ENSGGOT00000014763.2	ENSGGOP00000014352.2
ENSGGOG00000014703.2	ENSGGOT00000026484.1	ENSGGOP00000022169.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	5.80e-09	36.4	42	90

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/PHD

   S: 2    kvClvCgeggedekslveCekCrewfHpaClklsveeelpnsekwiCpkCr 52
           ++C +C+ +++ ++ ++eC+ C++wfH  C++ + ee+  + + + Cp+C+
   Q: 42   VYC-LCRLPYDVTRFMIECDMCQDWFHGSCVGVE-EEKAADIDLYHCPNCE 90
           69*.******************************.*******99******6 PP

Organism

Gorilla gorilla

Protein Sequence
(Fasta)

MNRSRAIVQR GRVLPPPAPL DTTNLAGRRT LQGRAKMASV PVYCLCRLPY DVTRFMIECD 60
MCQDWFHGSC VGVEEEKAAD IDLYHCPNCE VLHGPSISLV KKRRGSSKGH DTHKGKPVKT 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGAACAGGA GCCGCGGTGA GTACTCCGCC TCTACCCCGG CTGAAGCCCG CCCCCGCCGC 60
CACCTATTAA TTTTGTAGTT TGGAGTCACC GAGTTCACCT CCTCTCATAG GAGGAGAAGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR003347--JmjC_dom
IPR019786--Zinc_finger_PHD-type_CS
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS51184--JMJC
PS01359--ZF_PHD_1
PS50016--ZF_PHD_2

Pfam

PF02373--JmjC
PF00628--PHD

SMART

SM00558--JmjC
SM00249--PHD

Gene Ontology

GO:0031965--C:nuclear membrane
GO:0005730--C:nucleolus
GO:0003682--F:chromatin binding
GO:0071558--F:histone demethylase activity (H3-K27 specific)
GO:0051864--F:histone demethylase activity (H3-K36 specific)
GO:0032454--F:histone demethylase activity (H3-K9 specific)
GO:0035575--F:histone demethylase activity (H4-K20 specific)
GO:0005506--F:iron ion binding
GO:0008270--F:zinc ion binding
GO:0000082--P:G1/S transition of mitotic cell cycle
GO:0061188--P:negative regulation of chromatin silencing at rDNA
GO:0045943--P:positive regulation of transcription from RNA polymerase I promoter

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002427	Ailuropoda melanoleuca	96.70	0.00e+00	1562.00
IUUC-Atr-002986	Amborella trichopoda	44.00	4.00e-11	61.20
IUUC-Aca-004346	Anolis carolinensis	69.08	0.00e+00	1119.00
IUUC-Aly-005443	Arabidopsis lyrata	40.00	9.00e-11	60.10
IUUC-Ago-007912	Ashbya gossypii	28.26	5.00e-44	172.00
IUUC-Acl-008303	Aspergillus clavatus	32.73	3.00e-68	254.00
IUUC-Afl-008579	Aspergillus flavus	29.15	3.00e-29	124.00
IUUC-Afu-008903	Aspergillus fumigatus	32.59	8.00e-68	252.00
IUUC-Ani-009279	Aspergillus nidulans	32.21	8.00e-66	246.00
IUUC-Ang-009645	Aspergillus niger	30.89	9.00e-65	242.00
IUUC-Aor-010233	Aspergillus oryzae	31.94	1.00e-67	251.00
IUUC-Ate-010345	Aspergillus terreus	32.79	7.00e-70	259.00
IUUC-Ame-010945	Astyanax mexicanus	62.69	0.00e+00	1055.00
IUUC-Bdi-014153	Brachypodium distachyon	40.00	5.00e-11	60.80
IUUC-Cel-018303	Caenorhabditis elegans	45.04	2.00e-68	254.00
IUUC-Cja-018757	Callithrix jacchus	64.03	1.00e-160	560.00
IUUC-Cfa-021156	Canis familiaris	95.48	0.00e+00	1760.00
IUUC-Cpo-022284	Cavia porcellus	95.08	0.00e+00	1753.00
IUUC-Cre-022934	Chlamydomonas reinhardtii	36.71	8.00e-11	60.10
IUUC-Csa-023515	Chlorocebus sabaeus	99.03	0.00e+00	1816.00
IUUC-Cin-025140	Ciona intestinalis	48.00	5.00e-69	256.00
IUUC-Csv-025861	Ciona savignyi	45.24	1.00e-75	278.00
IUUC-Cne-026797	Cryptococcus neoformans	33.72	2.00e-48	187.00
IUUC-Cme-027118	Cyanidioschyzon merolae	30.47	3.00e-50	193.00
IUUC-Dre-028423	Danio rerio	63.11	0.00e+00	1047.00
IUUC-Dno-029446	Dasypus novemcinctus	95.80	0.00e+00	1200.00
IUUC-Dse-031402	Dothistroma septosporum	35.51	4.00e-66	247.00
IUUC-Dme-032039	Drosophila melanogaster	49.10	1.00e-79	291.00
IUUC-Ete-032380	Echinops telfairi	93.41	0.00e+00	1136.00
IUUC-Eca-034302	Equus caballus	95.93	0.00e+00	1744.00
IUUC-Fca-035578	Felis catus	96.31	0.00e+00	1776.00
IUUC-Fal-037017	Ficedula albicollis	62.10	0.00e+00	658.00
IUUC-Gmo-038789	Gadus morhua	61.29	0.00e+00	1091.00
IUUC-Gga-040290	Gallus gallus	62.31	0.00e+00	662.00
IUUC-Gac-041666	Gasterosteus aculeatus	79.96	0.00e+00	809.00
IUUC-Gma-042998	Glycine max	42.00	1.00e-10	59.70
IUUC-Hsa-045724	Homo sapiens	99.53	0.00e+00	1895.00
IUUC-Hvu-047723	Hordeum vulgare	29.33	2.00e-09	55.80
IUUC-Kpa-049384	Komagataella pastoris	32.70	1.00e-56	213.00
IUUC-Lch-049793	Latimeria chalumnae	66.18	0.00e+00	1191.00
IUUC-Lpe-051400	Leersia perrieri	42.86	9.00e-12	63.50
IUUC-Loc-051927	Lepisosteus oculatus	66.22	0.00e+00	664.00
IUUC-Lma-053190	Leptosphaeria maculans	35.82	3.00e-68	254.00
IUUC-Laf-053656	Loxodonta africana	94.65	0.00e+00	1612.00
IUUC-Mcc-055658	Macaca mulatta	99.03	0.00e+00	1816.00
IUUC-Mtr-057679	Medicago truncatula	41.79	1.00e-11	62.80
IUUC-Mla-058890	Melampsora laricipopulina	48.92	4.00e-75	274.00
IUUC-Mvi-060481	Microbotryum violaceum	39.26	4.00e-78	286.00
IUUC-Mmr-060993	Microcebus murinus	95.93	0.00e+00	1721.00
IUUC-Mdo-062097	Monodelphis domestica	70.02	0.00e+00	1215.00
IUUC-Mmu-063909	Mus musculus	94.05	0.00e+00	1706.00
IUUC-Mac-065355	Musa acuminata	40.00	3.00e-11	61.60
IUUC-Mpu-066429	Mustela putorius furo	96.59	0.00e+00	1724.00
IUUC-Mlu-067746	Myotis lucifugus	93.00	0.00e+00	1732.00
IUUC-Nfi-068537	Neosartorya fischeri	32.79	2.00e-68	254.00
IUUC-Nle-070143	Nomascus leucogenys	98.93	0.00e+00	1842.00
IUUC-Ont-072257	Oreochromis niloticus	78.12	0.00e+00	813.00
IUUC-Oan-073654	Ornithorhynchus anatinus	84.89	0.00e+00	865.00
IUUC-Ocu-074417	Oryctolagus cuniculus	95.81	0.00e+00	1706.00
IUUC-Oba-075188	Oryza barthii	44.00	1.00e-10	60.10
IUUC-Obr-076844	Oryza brachyantha	44.00	8.00e-11	60.10
IUUC-Ogl-077260	Oryza glaberrima	44.00	9.00e-11	60.10
IUUC-Ogu-078663	Oryza glumaepatula	44.00	4.00e-11	61.20
IUUC-Oin-079894	Oryza indica	44.00	4.00e-11	61.20
IUUC-Olo-080411	Oryza longistaminata	44.00	5.00e-11	60.80
IUUC-Ome-081623	Oryza meridionalis	44.00	4.00e-11	61.20
IUUC-Oni-082587	Oryza nivara	44.00	4.00e-11	61.20
IUUC-Opu-083591	Oryza punctata	44.00	3.00e-11	61.20
IUUC-Oru-084597	Oryza rufipogon	44.00	5.00e-11	60.80
IUUC-Osa-086057	Oryza sativa	44.00	4.00e-11	61.20
IUUC-Ola-087502	Oryzias latipes	61.63	0.00e+00	1013.00
IUUC-Olu-087802	Ostreococcus lucimarinus	42.86	2.00e-15	75.50
IUUC-Oga-088662	Otolemur garnettii	97.02	0.00e+00	1457.00
IUUC-Oar-090332	Ovis aries	96.25	0.00e+00	1700.00
IUUC-Ptr-091646	Pan troglodytes	99.39	0.00e+00	1481.00
IUUC-Pan-092122	Papio anubis	98.93	0.00e+00	1815.00
IUUC-Pma-094621	Petromyzon marinus	67.04	0.00e+00	641.00
IUUC-Pno-094984	Phaeosphaeria nodorum	35.29	7.00e-66	246.00
IUUC-Ppa-095609	Physcomitrella patens	41.20	2.00e-51	196.00
IUUC-Pfo-096107	Poecilia formosa	80.78	0.00e+00	816.00
IUUC-Pab-097635	Pongo abelii	89.48	0.00e+00	1559.00
IUUC-Pop-099324	Populus trichocarpa	42.00	2.00e-11	62.00
IUUC-Pca-100779	Procavia capensis	91.79	0.00e+00	957.00
IUUC-Ppe-101758	Prunus persica	42.00	3.00e-10	58.50
IUUC-Pva-102839	Pteropus vampyrus	82.64	0.00e+00	1425.00
IUUC-Pgr-103554	Puccinia graminis	46.29	9.00e-72	264.00
IUUC-Ptt-103859	Puccinia triticina	39.95	2.00e-76	280.00
IUUC-Pte-104241	Pyrenophora teres	33.99	1.00e-64	242.00
IUUC-Pyt-104741	Pyrenophora triticirepentis	33.74	1.00e-63	238.00
IUUC-Rno-105933	Rattus norvegicus	94.35	0.00e+00	1719.00
IUUC-Sce-106445	Saccharomyces cerevisiae	30.43	4.00e-46	179.00
IUUC-Sja-107763	Schizosaccharomyces japonicus	34.88	2.00e-47	184.00
IUUC-Spo-108120	Schizosaccharomyces pombe	41.10	5.00e-48	186.00
IUUC-Smo-109024	Selaginella moellendorffii	40.64	3.00e-53	202.00
IUUC-Sit-110474	Setaria italica	45.45	5.00e-12	63.90
IUUC-Sly-110932	Solanum lycopersicum	42.00	8.00e-11	60.10
IUUC-Stu-112357	Solanum tuberosum	42.00	9.00e-11	60.10
IUUC-Sbi-114098	Sorghum bicolor	45.45	4.00e-12	64.30
IUUC-Sre-115112	Sporisorium reilianum	39.20	1.00e-53	204.00
IUUC-Ssc-115645	Sus scrofa	96.98	0.00e+00	1657.00
IUUC-Tgu-117091	Taeniopygia guttata	62.31	0.00e+00	661.00
IUUC-Tru-118403	Takifugu rubripes	77.64	0.00e+00	798.00
IUUC-Tsy-119214	Tarsius syrichta	90.01	0.00e+00	1312.00
IUUC-Tni-119736	Tetraodon nigroviridis	79.91	0.00e+00	795.00
IUUC-Tca-121518	Theobroma cacao	44.00	5.00e-11	60.80
IUUC-Tae-125802	Triticum aestivum	40.00	5.00e-11	61.20
IUUC-Tur-126461	Triticum urartu	40.00	5.00e-11	60.50
IUUC-Tme-127054	Tuber melanosporum	31.03	5.00e-55	209.00
IUUC-Tbe-128138	Tupaia belangeri	96.33	0.00e+00	1482.00
IUUC-Ttr-128194	Tursiops truncatus	63.60	0.00e+00	642.00
IUUC-Uma-129458	Ustilago maydis	38.70	1.00e-53	204.00
IUUC-Vpa-130595	Vicugna pacos	92.53	0.00e+00	1092.00
IUUC-Vvi-131614	Vitis vinifera	44.00	6.00e-11	60.80
IUUC-Xtr-132307	Xenopus tropicalis	67.64	0.00e+00	1150.00
IUUC-Xma-134323	Xiphophorus maculatus	81.64	0.00e+00	821.00
IUUC-Yli-134626	Yarrowia lipolytica	36.68	1.00e-59	224.00
IUUC-Zma-134689	Zea mays	45.45	7.00e-12	63.50

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence