iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Gac-041860

Ensembl Protein ID

ENSGACP00000014297.1

UniProt Accession

G3P9M3; G3P9M3_GASAC

Protein Name

Tyrosine-protein kinase

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSGACG00000010799.1	ENSGACT00000014322.1	ENSGACP00000014297.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	1.10e-14	54.6	43	99

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 4    ekvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvekle 63
           +++ +++d++a+n+ +L +kkGd+ +v+   +++++W+ +++ ++g +G++P n+v++++
   Q: 43   DVFVAQHDFKATNNSDLPFKKGDKFKVL---QENGEWWLAKSLTTGEEGMIPCNYVARAD 99
           67899***********************...999**********************9986 PP

Organism

Gasterosteus aculeatus

Protein Sequence
(Fasta)

MGCSWSGQKR VKGDNFYKGK QNHEASNPSN HIVSGPVVKE TLDVFVAQHD FKATNNSDLP 60
FKKGDKFKVL QENGEWWLAK SLTTGEEGMI PCNYVARADT LEVEKWFLKD VSRRQTEQLL 120

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Nucleotide Sequence
(Fasta)

ATGGGCTGCA GTTGGAGTGG CCAGAAAAGA GTAAAAGGTG ACAACTTCTA CAAAGGAAAA 60
CAAAACCATG AGGCCTCCAA CCCGTCGAAT CACATCGTAA GTGGACCAGT TGTAAAGGAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0418--Kinase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0728--SH3 domain
KW-0808--Transferase
KW-0829--Tyrosine-protein kinase

Interpro

IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR001245--Ser-Thr/Tyr_kinase_cat_dom
IPR000980--SH2
IPR001452--SH3_domain
IPR008266--Tyr_kinase_AS
IPR020635--Tyr_kinase_cat_dom

PROSITE

PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00109--PROTEIN_KINASE_TYR
PS50001--SH2
PS50002--SH3

Pfam

PF07714--Pkinase_Tyr
PF00017--SH2
PF00018--SH3_1

PRINTS

PR00401--SH2DOMAIN
PR00452--SH3DOMAIN
PR00109--TYRKINASE

SMART

SM00252--SH2
SM00326--SH3
SM00219--TyrKc

Gene Ontology

GO:0005524--F:ATP binding
GO:0004715--F:non-membrane spanning protein tyrosine kinase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aca-004357	Anolis carolinensis	65.46	2.00e-177	615.00
IUUC-Ame-010642	Astyanax mexicanus	73.67	0.00e+00	764.00
IUUC-Cpo-021779	Cavia porcellus	69.37	0.00e+00	661.00
IUUC-Dre-027517	Danio rerio	73.36	0.00e+00	755.00
IUUC-Gmo-038861	Gadus morhua	75.96	0.00e+00	731.00
IUUC-Loc-052326	Lepisosteus oculatus	69.88	0.00e+00	722.00
IUUC-Mmr-061660	Microcebus murinus	68.47	0.00e+00	650.00
IUUC-Ont-072266	Oreochromis niloticus	80.82	0.00e+00	832.00
IUUC-Ola-086668	Oryzias latipes	82.10	0.00e+00	772.00
IUUC-Psi-093895	Pelodiscus sinensis	65.73	0.00e+00	650.00
IUUC-Pfo-096608	Poecilia formosa	79.18	0.00e+00	810.00
IUUC-Sha-107192	Sarcophilus harrisii	66.59	0.00e+00	637.00
IUUC-Tru-117621	Takifugu rubripes	76.17	0.00e+00	776.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence