iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ame-010996

Ensembl Protein ID

ENSAMXP00000018426.1

UniProt Accession

W5LF14; W5LF14_ASTMX

Genbank Protein ID

ENSAMXP00000018426

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

APWO01020079

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAMXG00000017885.1	ENSAMXT00000018426.1	ENSAMXP00000018426.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	7.70e-24	83.0	603	641
UBD/Beta-Prp	2.40e-40	138.8	470	640

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvllk 37
           gHtd+ +c++  +d t l++G+ D+t+++WDlr+g++l+
   Q: 603  GHTDGASCIDIsNDgTKLWTGGLDNTVRCWDLREGRQLQ 641
           8***********999*********************998 PP

UBD/Beta-Prp

   S: 48   lsgheaevtavkfspdgkilvtgseDrtikvwdls.....tgkcvhtlk..ghedsvlslsfspsgdklvsGshdrtirvwdletgqcl 129
           ls h + v av++s ++   v ++  + +kvwd+s     +  ++  l   + +++++s+++ p+g +l++G++ +t+ +wdl t +  
   Q: 470  LS-HGEVVCAVTISTSTR-HVYTGGKGCVKVWDISqpgskS--PMAQLDclNRDNYIRSCKLLPDGRTLIVGGEASTLSIWDLATPTPR 554
           43.444788899999985.555555589*******776432..333333559*********************************9987 PP
   S: 130  ee.tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgecv 215
            +  l+    +   ++++pd+++++s++ D+ + +Wdl +++l+r+++g htd   +++++ +g+ l +g+ld+tv+ wdl++g+ +
   Q: 555  IKaELTSSAPACYALAISPDNKVCFSCCSDGNIVVWDLHNQTLVRQFQG-HTDGASCIDISNDGTKLWTGGLDNTVRCWDLREGRQL 640
           765888888888899*********************************9.********************************99754 PP

Organism

Astyanax mexicanus

Protein Sequence
(Fasta)

MYPQGRHPVP LQPGQSFKFT VLETLDRIKE EFQFLQAQYH SLKLECEKLA SEKTEMQRHY 60
IMYYEMSYGL NIEMHKQAEI VKRLSAICAQ IIPFLSQEHQ QQVVQAVERA KQVTMAELNA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TGTCGTGTTT GTGTTGAAGC CAACAGGCAC AATATATTAC AGTCTAGGGC TCGCTGCTGA 60
AAAGCCTGCT GGATCTTCCA GTGACCTGCT GTTCTTTCCT GCTTTCCTGT ATTTTTTCTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR005617--Groucho/TLE_N
IPR009146--Groucho_enhance
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF03920--TLE_N
PF00400--WD40

PRINTS

PR01850--GROUCHOFAMLY

SMART

SM00320--WD40

Gene Ontology

GO:0005634--C:nucleus
GO:0006355--P:regulation of transcription, DNA-templated

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Dre-028144	Danio rerio	91.69	0.00e+00	1223.00
IUUC-Gac-041949	Gasterosteus aculeatus	77.37	0.00e+00	966.00
IUUC-Ont-072426	Oreochromis niloticus	87.87	0.00e+00	1209.00
IUUC-Ola-087404	Oryzias latipes	83.01	0.00e+00	913.00
IUUC-Pfo-096589	Poecilia formosa	79.59	0.00e+00	1008.00
IUUC-Tru-118327	Takifugu rubripes	85.00	0.00e+00	1175.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence