iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSONIG00000002262.1	ENSONIT00000002823.1	ENSONIP00000002822.1
ENSONIG00000002262.1	ENSONIT00000002824.1	ENSONIP00000002823.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.80e-23	82.1	619	657
UBD/Beta-Prp	1.80e-40	139.4	486	657

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvllk 37
           gHtd+ +c++  +d t l++G+ D+t+++WDlr+g++l+
   Q: 619  GHTDGASCIDIsNDgTKLWTGGLDNTVRCWDLREGRQLQ 657
           8***********999*********************998 PP

UBD/Beta-Prp

   S: 48   lsgheaevtavkfspdgkilvtgseDrtikvwdls.....tgkcvhtlkghedsvlslsfspsgdklvsGshdrtirvwdletgqclee 131
           ls h + v av++s ++   v ++  + +kvwd+s     ++       + +++++s+++ p+g +l++G++ +t+ +wdl t +   +
   Q: 486  LS-HGEVVCAVTISTSTR-HVYTGGKGCVKVWDISqpgskNPMAQLDCLNRDNYIRSCKILPDGRTLIVGGEASTLSIWDLATPTPRIK 572
           43.444788899999985.555555589*******988665555555669*********************************998776 PP
   S: 132  .tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgecvr 216
             l+    +   ++++pd+++++s++ D+ + +Wdl +++l+r+++g htd   +++++ +g+ l +g+ld+tv+ wdl++g+ ++
   Q: 573  aELTSSAPACYALAISPDNKVCFSCCSDGNIVVWDLHNQTLVRQFQG-HTDGASCIDISNDGTKLWTGGLDNTVRCWDLREGRQLQ 657
           5888888888899*********************************9.********************************997443 PP

Organism

Oreochromis niloticus

Protein Sequence
(Fasta)

MYPQGRHPVP LQPGQSFKFT VLETLDRIKE EFQFLQAQYH SLKLECEKLA SEKTEMQRHY 60
IMYYEMSYGL NIEMHKQAEI VKRLSAICAQ IIPFLSQEHQ QQVVQAVERA KQVTMAELNA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CAGTCAAGGC AGAGGCTTCA GTGTGTCACA GAGAGGGTGA AGAGGAGGAA AAAGCAGAGA 60
AGAAGACTAT TTGATCGAGC TGAGTGTTTG TTTACGTTTG TGTGTTTCGC CATTGGACGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR011042--6-blade_b-propeller_TolB-like
IPR005617--Groucho/TLE_N
IPR009146--Groucho_enhance
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF03920--TLE_N
PF00400--WD40

PRINTS

PR01850--GROUCHOFAMLY

SMART

SM00320--WD40

Gene Ontology

GO:0005634--C:nucleus
GO:0006355--P:regulation of transcription, DNA-templated

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ame-010996	Astyanax mexicanus	88.26	0.00e+00	1209.00
IUUC-Dre-028144	Danio rerio	87.05	0.00e+00	1197.00
IUUC-Gac-041949	Gasterosteus aculeatus	85.59	0.00e+00	1059.00
IUUC-Ola-087404	Oryzias latipes	92.47	0.00e+00	1032.00
IUUC-Pfo-096589	Poecilia formosa	88.83	0.00e+00	1143.00
IUUC-Tru-118327	Takifugu rubripes	91.90	0.00e+00	1245.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence