iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Dre-027839

Ensembl Protein ID

ENSDARP00000142575.1

UniProt Accession

A0A140LH45; A0A140LH45_DANRE

Genbank Protein ID

ENSDARP00000142575

Protein Name

Kinesin family member 21B

Genbank Nucleotide ID

CABZ01055641

Gene Name

kif21b

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSDARG00000009733.10	ENSDART00000172837.1	ENSDARP00000142575.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.50e-27	95.4	1313	1347
UBD/Beta-Prp	2.20e-43	149.5	1308	1547

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclafsdtllvsGsdDgtikvWDlrtgvl 35
           gHt +v cl+ +d ll +Gs D t+k+W+l tg  
   Q: 1313 GHTKPVLCLDATDELLFTGSKDRTCKMWNLVTGQE 1347
           8*******99878*****************99965 PP

UBD/Beta-Prp

   S: 45   lrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfspsgdklvsGshdrtirvwdlet.gqcle 130
           ++  +gh+++v +++  ++  +l tgs+Drt k w+l tg+ ++tl+gh ++v+s++++  +++lv + + + i+vwd++   +c++
   Q: 1308 VAMAEGHTKPVLCLDATDE--LLFTGSKDRTCKMWNLVTGQEIVTLRGHPNNVVSVKYCC-NSSLVFTVSTSFIKVWDIRDsAKCVR 1391
           66679**********9999..9**************************************.67777777799*******96157777 PP
   S: 131  e.....................tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsvyslsfdsng...k 193
           +                     t ++ +  +n ++++p+g++l ++ + +tvr Wdl++++   +ltg h +sv +l++ ++     
   Q: 1392 TftssgqvvsgdacagtttrtiTTAQGEYQINQIALNPSGSVLYAA-AGNTVRTWDLNRMQATGKLTG-HIGSVMCLTVGYSAggkD 1476
           7********************98888888999999***88544443.4579****************9.*********554444469 PP
   S: 194  elvsgsldgtvklwdlqtgecvrtlnght......dnvksvrfspnderlvsgssDgsiriWdlrsgdllktl 260
           ++++gs+d +vk++d+ +g   ++  +h+      d + +++++  ++ l sgs D+ i+ Wdlr+++l++++
   Q: 1477 QVITGSKDHYVKIFDVAEGAQGNIGPAHNfepphyDGIECLAVH--GDVLFSGSRDNGIKKWDLRQQELIQQI 1547
           9****************999988888888888888*********..*********************999876 PP

Organism

Danio rerio

Protein Sequence
(Fasta)

MATQNDCSVK VSLRIRPQMA KEKIEGCHIC TSVTPGEPQV LLGKDKAFTY DFVFDLDAHQ 60
QQIYSACVHK LIEGCFEGYN ATVFAYGQTG SGKTYTMGTG FDVSVSEDEQ GIIPRAVHQL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GAACGTACAT ACATATCAGA AGCCGTGTGC GCTTTCGGAT GTACGCTCGT GCACCTCTCG 60
CACATATGAC AGGATATAAG CTCGAAAGAA GAAGAAATGC CAATCTCCGT CATATGCCGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0505--Motor protein
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR019821--Kinesin_motor_CS
IPR001752--Kinesin_motor_dom
IPR027417--P-loop_NTPase
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00411--KINESIN_MOTOR_1
PS50067--KINESIN_MOTOR_2
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00225--Kinesin
PF00400--WD40

PRINTS

PR00380--KINESINHEAVY

SMART

SM00129--KISc
SM00320--WD40

Gene Ontology

GO:0005524--F:ATP binding
GO:0003777--F:microtubule motor activity
GO:0007018--P:microtubule-based movement

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001279	Ailuropoda melanoleuca	76.03	0.00e+00	1341.00
IUUC-Apl-003353	Anas platyrhynchos	56.35	0.00e+00	1665.00
IUUC-Aca-004506	Anolis carolinensis	72.78	0.00e+00	1337.00
IUUC-Ame-011515	Astyanax mexicanus	85.29	0.00e+00	2625.00
IUUC-Cja-018844	Callithrix jacchus	75.60	0.00e+00	1337.00
IUUC-Cfa-021187	Canis familiaris	75.33	0.00e+00	1342.00
IUUC-Cpo-022444	Cavia porcellus	72.39	0.00e+00	2138.00
IUUC-Csa-023852	Chlorocebus sabaeus	75.53	0.00e+00	1338.00
IUUC-Csv-026158	Ciona savignyi	59.15	4.00e-174	606.00
IUUC-Dno-030058	Dasypus novemcinctus	72.59	0.00e+00	1315.00
IUUC-Dor-030673	Dipodomys ordii	75.38	0.00e+00	1322.00
IUUC-Ete-032705	Echinops telfairi	68.76	0.00e+00	727.00
IUUC-Eca-033885	Equus caballus	74.67	0.00e+00	1303.00
IUUC-Eeu-035338	Erinaceus europaeus	58.71	0.00e+00	879.00
IUUC-Fca-035388	Felis catus	76.03	0.00e+00	1347.00
IUUC-Fal-037044	Ficedula albicollis	73.72	0.00e+00	1389.00
IUUC-Gmo-039034	Gadus morhua	70.30	0.00e+00	1266.00
IUUC-Gac-041328	Gasterosteus aculeatus	77.93	0.00e+00	1509.00
IUUC-Ggo-045392	Gorilla gorilla	75.18	0.00e+00	1334.00
IUUC-Hsa-046713	Homo sapiens	75.63	0.00e+00	1340.00
IUUC-Itr-049068	Ictidomys tridecemlineatus	74.65	0.00e+00	1218.00
IUUC-Lch-049786	Latimeria chalumnae	73.11	0.00e+00	2251.00
IUUC-Loc-052703	Lepisosteus oculatus	84.82	0.00e+00	1573.00
IUUC-Laf-054193	Loxodonta africana	69.27	0.00e+00	1247.00
IUUC-Mcc-055484	Macaca mulatta	74.12	0.00e+00	1330.00
IUUC-Meu-056278	Macropus eugenii	68.47	0.00e+00	904.00
IUUC-Mmr-061071	Microcebus murinus	73.44	0.00e+00	1325.00
IUUC-Mdo-062845	Monodelphis domestica	74.75	0.00e+00	1326.00
IUUC-Mmu-063967	Mus musculus	75.13	0.00e+00	1306.00
IUUC-Mpu-066448	Mustela putorius furo	74.62	0.00e+00	1329.00
IUUC-Nle-070037	Nomascus leucogenys	75.23	0.00e+00	1352.00
IUUC-Opr-070325	Ochotona princeps	73.21	0.00e+00	1288.00
IUUC-Ont-071851	Oreochromis niloticus	78.86	0.00e+00	1523.00
IUUC-Oan-073615	Ornithorhynchus anatinus	73.92	0.00e+00	1332.00
IUUC-Ocu-073855	Oryctolagus cuniculus	75.68	0.00e+00	1332.00
IUUC-Ola-086703	Oryzias latipes	76.97	0.00e+00	2374.00
IUUC-Oga-088171	Otolemur garnettii	73.23	0.00e+00	1315.00
IUUC-Ptr-090535	Pan troglodytes	74.40	0.00e+00	1328.00
IUUC-Pan-091917	Papio anubis	74.62	0.00e+00	1184.00
IUUC-Psi-093752	Pelodiscus sinensis	67.13	0.00e+00	1093.00
IUUC-Pfo-096827	Poecilia formosa	75.28	0.00e+00	2325.00
IUUC-Pab-098441	Pongo abelii	75.65	0.00e+00	1342.00
IUUC-Pca-100781	Procavia capensis	80.35	0.00e+00	773.00
IUUC-Pva-103099	Pteropus vampyrus	72.59	0.00e+00	1009.00
IUUC-Rno-105872	Rattus norvegicus	74.92	0.00e+00	1336.00
IUUC-Sha-107097	Sarcophilus harrisii	73.89	0.00e+00	1298.00
IUUC-Ssc-115638	Sus scrofa	74.48	0.00e+00	1073.00
IUUC-Tru-118242	Takifugu rubripes	76.69	0.00e+00	2406.00
IUUC-Tni-119976	Tetraodon nigroviridis	78.84	0.00e+00	910.00
IUUC-Ttr-128824	Tursiops truncatus	71.77	0.00e+00	1248.00
IUUC-Xtr-131798	Xenopus tropicalis	62.29	0.00e+00	1116.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence