iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Loc-052070

Ensembl Protein ID

ENSLOCP00000000955.1

UniProt Accession

W5LXU8; W5LXU8_LEPOC

Genbank Protein ID

ENSLOCP00000000955

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AHAT01003361

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLOCG00000000838.1	ENSLOCT00000000959.1	ENSLOCP00000000955.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	1.50e-63	215.2	168	649

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrellle....kkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefs 85
           +GlkN+gNtC++ +v+Q+L+n+ e+++l+l+       ++l++++++ ++ +++++l++lf+ ++ sk+k+v+p++ +++lk++ ++ +
   Q: 168  VGLKNVGNTCWFSAVIQSLFNLLEFQRLVLHysppACAQDLPRNQKERRNLPFMRELRHLFSLMVGSKRKYVDPSRAVEILKDAFKS-T 255
           6******************************88887778888888888889*******************************99998.7 PP
   S: 86   gyeqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlsl 174
            ++qqD++Ef++ lld le++++                   + +ee++ +k+k+++++lF g++    +    +++ + +e f +++l
   Q: 256  DSQQQDVSEFTHKLLDWLEDAFQ------------------IKAEEEREGEKTKNPMVELFYGRFLAVGVH--EGKKFENTEMFGQYPL 324
           8*********************2..................2234567899***************77766..456667799******* PP
   S: 175  pvpgkeetkkeslqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdlsp 263
           +v+g +     +l++cLe+ + e e+e+   +++e+  k+    +++++++lP+vL+++L+Rf+f+++ +++eki+ k+efp +L +++
   Q: 325  QVNGFK-----DLHECLEAAMIEGEIES---LHSENSAKS---GQEHWFTELPPVLTFELSRFEFNQALGRPEKIHHKLEFPAMLYMDR 402
           ******.....9**************96...899998754...589******************************************* PP
   S: 264  fcts..................................................................................... 267
           ++ +                                                                                     
   Q: 403  YMDKnrevtrikreeirrlkehltvlqqrlerylsygsgpkrfpladvlqyamefasskpvctspvedidttappggttapqpapstad 491
           ****7777777777777777777777777777777666666666666666666666666666666666666666666666666655555 PP
   S: 268  ......peekqke............................................................................ 274
                 p     e                                                                            
   Q: 492  qgpscsP-----Etpatppsqhrvpihkpftqsrippdlpmhpaprhiteeelrvlesclhrwrsevendtrdlqgsiarihrtielmy 575
           5555550.....05555555555556666666666666666666666666666666666666777777777777777778888888888 PP
   S: 275  ......kkkYeLiavvvHsGslssGHYvayvknekgk.WllfdDskVtevkeeevleetg.....staYvlfYk 336
                 ++ Y+L+av+vH+G+++ GHY+ay++n +++ W++++D +Vt++++ee  +++      ++aY+l+Y 
   Q: 576  sdksmmQVPYRLHAVLVHEGQANAGHYWAYIYNPHHRrWMKYNDISVTKSSWEELMRDSFggyrnASAYCLMYI 649
           888888***************************87777****************9997779************6 PP

Organism

Lepisosteus oculatus

Protein Sequence
(Fasta)

MTVEQNVLQQ HSQKHQQTLL NQLREVTGTT DVQLLQQALQ VSNGDLAEAV AFLTEKSTKV 60
PQQDEATYYQ TAQIGNDRYI SVGSQADTNV IDLTGDDKDD LQRAIALSLE ESNRAFRETG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGACCGTGG AGCAGAATGT CCTGCAGCAG CACTCTCAGA AGGTAGGGTG GGTGTTGGGG 60
AGCTGCTGCC GAGAAGCGCC GCGGCTGTGG CTCAGTGCCC GGCAGGGTGG ACGGTCTCCG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR009060--UBA-like
IPR003903--UIM_dom
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS50330--UIM
PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

SMART

SM00726--UIM

Gene Ontology

GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0009953--P:dorsal/ventral pattern formation
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001340	Ailuropoda melanoleuca	75.54	0.00e+00	1689.00
IUUC-Apl-004030	Anas platyrhynchos	79.07	0.00e+00	1782.00
IUUC-Aca-004753	Anolis carolinensis	62.95	0.00e+00	1015.00
IUUC-Afu-008871	Aspergillus fumigatus	24.37	3.00e-15	78.20
IUUC-Ame-010624	Astyanax mexicanus	80.89	0.00e+00	1295.00
IUUC-Bgr-011993	Blumeria graminis	36.49	1.00e-10	62.80
IUUC-Bta-013166	Bos taurus	74.82	0.00e+00	1185.00
IUUC-Cel-018346	Caenorhabditis elegans	27.46	2.00e-30	128.00
IUUC-Cja-019150	Callithrix jacchus	77.73	0.00e+00	1746.00
IUUC-Cfa-020649	Canis familiaris	77.64	0.00e+00	1753.00
IUUC-Cpo-021807	Cavia porcellus	75.56	0.00e+00	1735.00
IUUC-Csa-023388	Chlorocebus sabaeus	77.81	0.00e+00	1758.00
IUUC-Cho-024717	Choloepus hoffmanni	41.50	4.00e-160	558.00
IUUC-Cin-025302	Ciona intestinalis	37.56	2.00e-99	356.00
IUUC-Csv-025911	Ciona savignyi	33.78	7.00e-136	478.00
IUUC-Dre-028016	Danio rerio	83.87	0.00e+00	1886.00
IUUC-Dno-029495	Dasypus novemcinctus	75.64	0.00e+00	1741.00
IUUC-Dor-030948	Dipodomys ordii	64.83	0.00e+00	1176.00
IUUC-Eca-034300	Equus caballus	49.68	0.00e+00	1005.00
IUUC-Eeu-034458	Erinaceus europaeus	49.95	0.00e+00	922.00
IUUC-Fca-035876	Felis catus	75.62	0.00e+00	1209.00
IUUC-Fal-036762	Ficedula albicollis	79.84	0.00e+00	1058.00
IUUC-Gmo-039490	Gadus morhua	79.55	0.00e+00	1756.00
IUUC-Gga-040817	Gallus gallus	81.47	0.00e+00	1848.00
IUUC-Gac-042473	Gasterosteus aculeatus	81.15	0.00e+00	1796.00
IUUC-Ggo-044939	Gorilla gorilla	74.05	0.00e+00	1639.00
IUUC-Hsa-046204	Homo sapiens	75.24	0.00e+00	1206.00
IUUC-Kpa-049349	Komagataella pastoris	27.75	2.00e-09	58.20
IUUC-Lch-049572	Latimeria chalumnae	79.27	0.00e+00	1768.00
IUUC-Laf-054426	Loxodonta africana	78.21	0.00e+00	1107.00
IUUC-Mcc-055858	Macaca mulatta	77.93	0.00e+00	1779.00
IUUC-Meu-056416	Macropus eugenii	44.73	0.00e+00	826.00
IUUC-Mga-059808	Meleagris gallopavo	73.65	0.00e+00	1599.00
IUUC-Mmr-060987	Microcebus murinus	77.91	0.00e+00	1739.00
IUUC-Mmu-064245	Mus musculus	74.15	0.00e+00	1218.00
IUUC-Mpu-066304	Mustela putorius furo	77.08	0.00e+00	1727.00
IUUC-Mlu-067139	Myotis lucifugus	78.27	0.00e+00	1228.00
IUUC-Nle-069075	Nomascus leucogenys	75.46	0.00e+00	1209.00
IUUC-Ont-072150	Oreochromis niloticus	82.12	0.00e+00	1897.00
IUUC-Oan-073054	Ornithorhynchus anatinus	72.55	0.00e+00	1585.00
IUUC-Ocu-074102	Oryctolagus cuniculus	75.64	0.00e+00	1744.00
IUUC-Ola-086529	Oryzias latipes	78.01	0.00e+00	1712.00
IUUC-Oga-088939	Otolemur garnettii	74.97	0.00e+00	1196.00
IUUC-Oar-090266	Ovis aries	77.35	0.00e+00	1725.00
IUUC-Ptr-090546	Pan troglodytes	75.36	0.00e+00	1209.00
IUUC-Pan-092311	Papio anubis	77.84	0.00e+00	1778.00
IUUC-Psi-093459	Pelodiscus sinensis	86.13	0.00e+00	1112.00
IUUC-Pfo-096726	Poecilia formosa	81.03	0.00e+00	1868.00
IUUC-Pab-097608	Pongo abelii	75.53	0.00e+00	1664.00
IUUC-Pca-100718	Procavia capensis	67.47	0.00e+00	1192.00
IUUC-Pva-103150	Pteropus vampyrus	72.20	0.00e+00	1248.00
IUUC-Rno-105727	Rattus norvegicus	74.03	0.00e+00	1190.00
IUUC-Sha-107051	Sarcophilus harrisii	80.50	0.00e+00	1242.00
IUUC-Sar-113097	Sorex araneus	69.38	0.00e+00	1517.00
IUUC-Ssc-115877	Sus scrofa	72.82	0.00e+00	1191.00
IUUC-Tgu-117473	Taeniopygia guttata	72.25	0.00e+00	1592.00
IUUC-Tru-118135	Takifugu rubripes	72.10	0.00e+00	1535.00
IUUC-Tsy-119471	Tarsius syrichta	72.38	0.00e+00	1504.00
IUUC-Tni-120139	Tetraodon nigroviridis	74.80	0.00e+00	1078.00
IUUC-Tbe-127549	Tupaia belangeri	70.36	0.00e+00	1524.00
IUUC-Ttr-128896	Tursiops truncatus	71.96	0.00e+00	1582.00
IUUC-Vpa-130500	Vicugna pacos	77.39	0.00e+00	1122.00
IUUC-Xtr-132896	Xenopus tropicalis	78.85	0.00e+00	1253.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence