iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Bra-016651

Ensembl Protein ID

Bra019432.1-P

UniProt Accession

M4DSD9; M4DSD9_BRARP

Protein Name

Protein HIRA

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
Bra019432	Bra019432.1	Bra019432.1-P

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	3.40e-26	91.2	124	161
UBD/Beta-Prp	9.00e-44	150.8	16	206

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvll 36
           gHt++v ++++ +d  +l+sGs D+t+++W++rtg ++
   Q: 124  GHTADVVDINWsPDdSMLASGSLDNTVHIWNMRTGICT 161
           8***********777********************985 PP

UBD/Beta-Prp

   S: 12   vitcvkfspdksllatgsrdgtikvwdvttgkl...........lrslsgheaevtavkfspdgkilvtgseDrtikvw................. 79
           +i ++++ p+++ +atg+ d+++++w++++ +            l++l +h + v++v++ ++g + ++gs+D++i+v                  
   Q: 16   QIFSIDVQPNGERFATGGGDHKVRIWNMKSVDRdlqnldpkerlLATLRDHFGSVNCVRWAKHGRYVASGSDDHVIQVHerkpgsgttefgsgeap 111
           5667999**********************988899********************************************88888888888888888 PP
   S: 80   dlstgkcvhtlkghedsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtl 175
           d+++ k v+tl+gh+++v+++++sp+++ l+sGs d+t+++w+++tg c   +l+gh ++v +v+++p g+ ++s s+D+tv +W+ +  ++ ++ 
   Q: 112  DVENWKAVMTLRGHTADVVDINWSPDDSMLASGSLDNTVHIWNMRTGICTT-VLRGHLSLVKGVTWDPIGSFVASQSDDKTVIIWRTSDWSMAHRT 206
           888***********************************************9.*********************************99665555554 PP

Organism

Brassica rapa

Functional Description
(View)

Required for replication-independent chromatin assembly and for the periodic repression of histone gene transcription during the cell cycle.

Protein Sequence
(Fasta)

MIAEKPVWVK HEGLQQIFSI DVQPNGERFA TGGGDHKVRI WNMKSVDRDL QNLDPKERLL 60
ATLRDHFGSV NCVRWAKHGR YVASGSDDHV IQVHERKPGS GTTEFGSGEA PDVENWKAVM 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGATTGCGG AGAAACCCGT ATGGGTAAAA CATGAAGGAT TGCAGCAGAT ATTCTCCATT 60
GATGTTCAAC CAAACGGTGA ACGCTTTGCC ACAGGCGGTG GTGATCACAA GGTCTCTCCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0156--Chromatin regulator
KW-0181--Complete proteome
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0677--Repeat
KW-0678--Repressor
KW-0804--Transcription
KW-0805--Transcription regulation
KW-0853--WD repeat

Interpro

IPR031120--HIR1
IPR011494--Hira
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF07569--Hira
PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0005634--C:nucleus
GO:0016569--P:covalent chromatin modification
GO:0006355--P:regulation of transcription, DNA-templated
GO:0006351--P:transcription, DNA-templated

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-001039	Aegilops tauschii	62.22	0.00e+00	1239.00
IUUC-Aml-001723	Ailuropoda melanoleuca	40.84	2.00e-79	290.00
IUUC-Atr-003132	Amborella trichopoda	65.30	0.00e+00	1254.00
IUUC-Apl-003197	Anas platyrhynchos	36.80	7.00e-79	288.00
IUUC-Aca-004733	Anolis carolinensis	35.74	5.00e-83	302.00
IUUC-Aly-005446	Arabidopsis lyrata	85.38	0.00e+00	1728.00
IUUC-Ath-007627	Arabidopsis thaliana	81.53	0.00e+00	1708.00
IUUC-Ago-007766	Ashbya gossypii	34.98	7.00e-61	228.00
IUUC-Acl-008104	Aspergillus clavatus	33.40	1.00e-74	274.00
IUUC-Afl-008591	Aspergillus flavus	32.95	9.00e-73	268.00
IUUC-Afu-008781	Aspergillus fumigatus	32.32	2.00e-66	247.00
IUUC-Ani-009272	Aspergillus nidulans	29.69	2.00e-56	214.00
IUUC-Ang-009655	Aspergillus niger	32.63	2.00e-71	264.00
IUUC-Aor-010119	Aspergillus oryzae	32.95	1.00e-72	268.00
IUUC-Ate-010530	Aspergillus terreus	29.19	3.00e-56	213.00
IUUC-Bgr-012237	Blumeria graminis	34.36	2.00e-65	244.00
IUUC-Bta-013320	Bos taurus	40.84	3.00e-79	290.00
IUUC-Bci-013795	Botrytis cinerea	33.80	2.00e-70	260.00
IUUC-Bdi-014075	Brachypodium distachyon	65.03	0.00e+00	1276.00
IUUC-Bol-016440	Brassica oleracea	97.06	0.00e+00	1994.00
IUUC-Cel-018692	Caenorhabditis elegans	29.74	2.00e-45	177.00
IUUC-Cja-018987	Callithrix jacchus	34.64	8.00e-71	261.00
IUUC-Cfa-020132	Canis familiaris	40.84	3.00e-79	290.00
IUUC-Cpo-021484	Cavia porcellus	41.12	1.00e-82	301.00
IUUC-Cre-022846	Chlamydomonas reinhardtii	35.48	6.00e-72	265.00
IUUC-Csa-023081	Chlorocebus sabaeus	41.12	1.00e-82	301.00
IUUC-Cin-025182	Ciona intestinalis	37.33	9.00e-84	305.00
IUUC-Csv-026154	Ciona savignyi	36.42	5.00e-83	302.00
IUUC-Cgl-026655	Colletotrichum gloeosporioides	32.97	3.00e-64	239.00
IUUC-Cne-026891	Cryptococcus neoformans	39.53	6.00e-82	298.00
IUUC-Cme-027349	Cyanidioschyzon merolae	27.93	2.00e-50	194.00
IUUC-Dre-027655	Danio rerio	41.07	9.00e-81	295.00
IUUC-Dno-029557	Dasypus novemcinctus	40.62	6.00e-68	252.00
IUUC-Dor-030687	Dipodomys ordii	35.96	4.00e-62	233.00
IUUC-Dse-031334	Dothistroma septosporum	33.03	1.00e-70	261.00
IUUC-Dme-031746	Drosophila melanogaster	38.44	2.00e-82	300.00
IUUC-Ete-032384	Echinops telfairi	32.97	2.00e-60	227.00
IUUC-Eca-033430	Equus caballus	41.10	8.00e-80	291.00
IUUC-Fca-036121	Felis catus	40.41	1.00e-79	291.00
IUUC-Fal-036817	Ficedula albicollis	40.05	4.00e-78	286.00
IUUC-Fox-037906	Fusarium oxysporum	35.22	7.00e-70	258.00
IUUC-Fso-038409	Fusarium solani	35.42	4.00e-68	253.00
IUUC-Gmo-039151	Gadus morhua	38.95	8.00e-82	298.00
IUUC-Ggr-040016	Gaeumannomyces graminis	34.35	8.00e-68	252.00
IUUC-Gga-040936	Gallus gallus	35.57	6.00e-82	298.00
IUUC-Gac-041405	Gasterosteus aculeatus	42.37	2.00e-79	290.00
IUUC-Gma-044252	Glycine max	70.95	0.00e+00	1387.00
IUUC-Ggo-045430	Gorilla gorilla	41.12	7.00e-83	301.00
IUUC-Hsa-046442	Homo sapiens	41.12	8.00e-83	301.00
IUUC-Hvu-047587	Hordeum vulgare	64.40	0.00e+00	1196.00
IUUC-Itr-048910	Ictidomys tridecemlineatus	41.72	2.00e-61	228.00
IUUC-Kpa-049145	Komagataella pastoris	32.14	2.00e-58	220.00
IUUC-Lch-050474	Latimeria chalumnae	40.61	3.00e-80	293.00
IUUC-Lpe-051209	Leersia perrieri	62.89	0.00e+00	1217.00
IUUC-Loc-052119	Lepisosteus oculatus	36.67	3.00e-80	293.00
IUUC-Lma-053237	Leptosphaeria maculans	25.45	2.00e-87	317.00
IUUC-Laf-053718	Loxodonta africana	38.09	5.00e-83	302.00
IUUC-Mcc-055621	Macaca mulatta	39.88	8.00e-71	261.00
IUUC-Meu-055914	Macropus eugenii	39.86	9.00e-53	201.00
IUUC-Mor-057090	Magnaporthe oryzae	33.94	3.00e-66	246.00
IUUC-Mpo-057364	Magnaporthe poae	33.91	2.00e-68	253.00
IUUC-Mtr-057744	Medicago truncatula	68.66	0.00e+00	1389.00
IUUC-Mla-058914	Melampsora laricipopulina	26.86	9.00e-81	294.00
IUUC-Mga-060181	Meleagris gallopavo	34.22	1.00e-78	288.00
IUUC-Mvi-060432	Microbotryum violaceum	32.40	1.00e-56	214.00
IUUC-Mmr-060871	Microcebus murinus	41.12	9.00e-83	301.00
IUUC-Mdo-062301	Monodelphis domestica	37.23	1.00e-82	301.00
IUUC-Mmu-063888	Mus musculus	41.12	2.00e-82	300.00
IUUC-Mac-065137	Musa acuminata	67.19	0.00e+00	1238.00
IUUC-Mpu-066732	Mustela putorius furo	40.84	2.00e-79	290.00
IUUC-Mlu-067542	Myotis lucifugus	40.84	2.00e-79	290.00
IUUC-Nfi-068396	Neosartorya fischeri	32.12	9.00e-66	245.00
IUUC-Ncr-068842	Neurospora crassa	36.54	1.00e-68	254.00
IUUC-Nle-070156	Nomascus leucogenys	41.12	9.00e-83	301.00
IUUC-Opr-070808	Ochotona princeps	39.08	9.00e-52	198.00
IUUC-Ont-072105	Oreochromis niloticus	36.07	5.00e-80	292.00
IUUC-Ocu-074962	Oryctolagus cuniculus	36.25	8.00e-80	291.00
IUUC-Oba-075178	Oryza barthii	65.56	0.00e+00	1216.00
IUUC-Obr-076399	Oryza brachyantha	64.49	0.00e+00	1243.00
IUUC-Ogu-078797	Oryza glumaepatula	65.56	0.00e+00	1216.00
IUUC-Oin-080085	Oryza indica	65.18	0.00e+00	1149.00
IUUC-Olo-081048	Oryza longistaminata	82.66	6.00e-161	561.00
IUUC-Ome-081324	Oryza meridionalis	65.03	0.00e+00	1214.00
IUUC-Oni-082548	Oryza nivara	65.56	0.00e+00	1217.00
IUUC-Opu-084008	Oryza punctata	80.20	0.00e+00	714.00
IUUC-Oru-084339	Oryza rufipogon	65.66	0.00e+00	1217.00
IUUC-Osa-085782	Oryza sativa	65.66	0.00e+00	1217.00
IUUC-Ola-087302	Oryzias latipes	36.50	2.00e-77	283.00
IUUC-Olu-087611	Ostreococcus lucimarinus	42.03	2.00e-114	407.00
IUUC-Oga-087935	Otolemur garnettii	40.84	1.00e-79	291.00
IUUC-Oar-089229	Ovis aries	36.64	3.00e-62	233.00
IUUC-Ptr-090715	Pan troglodytes	41.12	8.00e-83	301.00
IUUC-Pan-092318	Papio anubis	40.00	4.00e-80	293.00
IUUC-Psi-094053	Pelodiscus sinensis	36.73	4.00e-80	293.00
IUUC-Pno-094985	Phaeosphaeria nodorum	32.25	3.00e-59	223.00
IUUC-Ppa-095819	Physcomitrella patens	47.93	0.00e+00	887.00
IUUC-Pfo-096857	Poecilia formosa	40.56	4.00e-78	286.00
IUUC-Pab-098047	Pongo abelii	41.12	9.00e-83	301.00
IUUC-Pop-099587	Populus trichocarpa	71.07	0.00e+00	1389.00
IUUC-Pca-100558	Procavia capensis	47.96	3.00e-47	183.00
IUUC-Ppe-101261	Prunus persica	70.82	0.00e+00	1362.00
IUUC-Pva-102683	Pteropus vampyrus	40.77	6.00e-80	292.00
IUUC-Pgr-103660	Puccinia graminis	36.83	5.00e-59	222.00
IUUC-Ptt-103900	Puccinia triticina	37.43	3.00e-60	226.00
IUUC-Pte-104209	Pyrenophora teres	25.59	1.00e-88	320.00
IUUC-Pyt-104802	Pyrenophora triticirepentis	34.04	3.00e-69	256.00
IUUC-Rno-105566	Rattus norvegicus	41.12	9.00e-83	301.00
IUUC-Sce-106291	Saccharomyces cerevisiae	27.31	2.00e-68	253.00
IUUC-Sha-107514	Sarcophilus harrisii	34.61	1.00e-68	254.00
IUUC-Sja-107833	Schizosaccharomyces japonicus	33.20	1.00e-71	264.00
IUUC-Spo-108162	Schizosaccharomyces pombe	32.60	9.00e-71	261.00
IUUC-Smo-109186	Selaginella moellendorffii	49.53	0.00e+00	888.00
IUUC-Sit-110730	Setaria italica	64.92	0.00e+00	1227.00
IUUC-Sly-111547	Solanum lycopersicum	67.73	0.00e+00	1301.00
IUUC-Stu-112705	Solanum tuberosum	67.96	0.00e+00	1299.00
IUUC-Sar-113222	Sorex araneus	33.91	6.00e-73	268.00
IUUC-Sbi-114272	Sorghum bicolor	66.28	0.00e+00	1239.00
IUUC-Sre-115061	Sporisorium reilianum	32.86	2.00e-69	257.00
IUUC-Ssc-116364	Sus scrofa	40.31	3.00e-79	290.00
IUUC-Tgu-116645	Taeniopygia guttata	36.66	2.00e-78	286.00
IUUC-Tru-117590	Takifugu rubripes	36.44	1.00e-83	305.00
IUUC-Tsy-119212	Tarsius syrichta	41.54	2.00e-68	254.00
IUUC-Tni-119915	Tetraodon nigroviridis	36.95	1.00e-83	304.00
IUUC-Tca-121765	Theobroma cacao	69.66	0.00e+00	1390.00
IUUC-Tre-121887	Trichoderma reesei	32.58	1.00e-60	228.00
IUUC-Tvi-122262	Trichoderma virens	33.85	2.00e-59	224.00
IUUC-Tae-123009	Triticum aestivum	58.73	0.00e+00	761.00
IUUC-Tur-126483	Triticum urartu	64.54	0.00e+00	1263.00
IUUC-Tme-127202	Tuber melanosporum	28.80	2.00e-52	200.00
IUUC-Tbe-127350	Tupaia belangeri	33.62	2.00e-47	184.00
IUUC-Ttr-129077	Tursiops truncatus	31.30	7.00e-70	258.00
IUUC-Uma-129465	Ustilago maydis	32.18	5.00e-71	262.00
IUUC-Vda-129844	Verticillium dahliae	33.92	1.00e-66	248.00
IUUC-Vvi-131397	Vitis vinifera	71.20	0.00e+00	1394.00
IUUC-Xtr-132057	Xenopus tropicalis	40.61	2.00e-81	296.00
IUUC-Xma-134139	Xiphophorus maculatus	40.12	7.00e-68	251.00
IUUC-Yli-134424	Yarrowia lipolytica	34.99	3.00e-63	236.00
IUUC-Zma-135839	Zea mays	65.62	0.00e+00	1251.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence