iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ssc-116284

Ensembl Protein ID

ENSSSCP00000031038.1

UniProt Accession

A9QT41; F1RZ22; A9QT41_PIG

Genbank Protein ID

ABX57883.1

Protein Name

Inhibitor of kappa light polypeptide gene enhancer in B-cells kinase gamma

Genbank Nucleotide ID

CU862037

Gene Name

IKBKG

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSSCG00000012825.3	ENSSSCT00000033026.1	ENSSSCP00000030895.1
ENSSSCG00000012825.3	ENSSSCT00000033887.1	ENSSSCP00000029349.1
ENSSSCG00000012825.3	ENSSSCT00000035592.1	ENSSSCP00000031038.1
ENSSSCG00000012825.3	ENSSSCT00000034165.1	ENSSSCP00000030998.1
ENSSSCG00000012825.3	ENSSSCT00000033807.1	ENSSSCP00000030280.1
ENSSSCG00000012825.3	ENSSSCT00000034575.1	ENSSSCP00000028967.1
ENSSSCG00000012825.3	ENSSSCT00000035343.1	ENSSSCP00000030437.1
ENSSSCG00000012825.3	ENSSSCT00000032825.1	ENSSSCP00000028895.1
ENSSSCG00000012825.3	ENSSSCT00000033483.1	ENSSSCP00000028267.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/Alpha-Helix/UBAN	2.60e-25	88.4	291	350

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/Alpha-Helix/UBAN

   S: 1    keelletvevLkqQveiYkeDFqaERadRErlneekeeLqeqveklqkqvsklndslkas 60
           +++++etv+vLk+Q++iYk+DFqaER++RE+l+e+ke Lqeq+e+lq+++s+l+ s+++s
   Q: 291  HKIVMETVPVLKAQADIYKADFQAERQAREQLAERKELLQEQLEQLQREYSRLKTSCQES 350
           899*******************************************************98 PP

Organism

Sus scrofa

Protein Sequence
(Fasta)

MSRTPWKSQP CEMVQPSGGP AGDQDVLGEE SSLGKPTMLH LPSEQGAPET FQRCLEENQE 60
LRDAIRQSNQ MLRERCEELQ RFQGSQREEK EFLMQKFCEA RRLVERLSLE KLELRRQREQ 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGAATTTGGC AGCCCGAGAA GGGAAGGGCG ACCGCGGAAC CCGAACTTTC TCCGAGCGCC 60
GGGGTCCGAG GAGCGCTCGG GACCCGCCGC TCCCGCCCTT CTCACGTCGG ACCGACTCTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0418--Kinase
KW-1185--Reference proteome
KW-0808--Transferase

Interpro

IPR032419--CC2-LZ_dom
IPR021063--NEMO_N
IPR034735--ZF_CCHC_NOA

PROSITE

PS51801--ZF_CCHC_NOA

Pfam

PF16516--CC2-LZ
PF11577--NEMO

Gene Ontology

GO:0008385--C:IkappaB kinase complex
GO:0072686--C:mitotic spindle
GO:0005634--C:nucleus
GO:0000922--C:spindle pole
GO:0000151--C:ubiquitin ligase complex
GO:0070530--F:K63-linked polyubiquitin binding
GO:0016301--F:kinase activity
GO:0006974--P:cellular response to DNA damage stimulus
GO:0051650--P:establishment of vesicle localization
GO:0043123--P:positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0051092--P:positive regulation of NF-kappaB transcription factor activity
GO:0045944--P:positive regulation of transcription from RNA polymerase II promoter

KEGG

ssc:100127355

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002336	Ailuropoda melanoleuca	92.60	0.00e+00	652.00
IUUC-Aca-004653	Anolis carolinensis	60.80	4.00e-102	364.00
IUUC-Bta-012778	Bos taurus	89.50	0.00e+00	654.00
IUUC-Cja-018954	Callithrix jacchus	89.50	0.00e+00	630.00
IUUC-Cfa-020778	Canis familiaris	90.69	0.00e+00	682.00
IUUC-Cpo-022327	Cavia porcellus	83.53	5.00e-143	500.00
IUUC-Csa-023340	Chlorocebus sabaeus	89.28	2.00e-155	541.00
IUUC-Dre-028819	Danio rerio	45.29	5.00e-57	215.00
IUUC-Dno-029566	Dasypus novemcinctus	84.80	8.00e-165	572.00
IUUC-Dor-031122	Dipodomys ordii	91.78	1.00e-32	133.00
IUUC-Eca-033895	Equus caballus	83.77	6.00e-154	536.00
IUUC-Eeu-034478	Erinaceus europaeus	79.71	4.00e-142	497.00
IUUC-Fca-035990	Felis catus	91.29	5.00e-125	441.00
IUUC-Gmo-038622	Gadus morhua	46.02	1.00e-60	226.00
IUUC-Gac-041917	Gasterosteus aculeatus	50.00	6.00e-60	224.00
IUUC-Ggo-045478	Gorilla gorilla	89.26	3.00e-164	571.00
IUUC-Hsa-046243	Homo sapiens	89.02	8.00e-164	569.00
IUUC-Itr-048520	Ictidomys tridecemlineatus	87.83	0.00e+00	633.00
IUUC-Lch-050187	Latimeria chalumnae	59.14	2.00e-106	378.00
IUUC-Loc-052627	Lepisosteus oculatus	56.08	2.00e-64	240.00
IUUC-Laf-054387	Loxodonta africana	85.27	2.00e-140	491.00
IUUC-Mcc-054611	Macaca mulatta	89.02	8.00e-164	569.00
IUUC-Meu-056530	Macropus eugenii	63.81	5.00e-97	347.00
IUUC-Mmr-061028	Microcebus murinus	87.44	1.00e-180	625.00
IUUC-Mdo-062520	Monodelphis domestica	63.11	6.00e-119	420.00
IUUC-Mmu-063925	Mus musculus	84.49	2.00e-158	551.00
IUUC-Mpu-066392	Mustela putorius furo	88.07	7.00e-166	576.00
IUUC-Mlu-067374	Myotis lucifugus	85.28	4.00e-166	577.00
IUUC-Nle-069085	Nomascus leucogenys	86.71	2.00e-79	287.00
IUUC-Ont-071385	Oreochromis niloticus	48.08	5.00e-60	225.00
IUUC-Oan-073347	Ornithorhynchus anatinus	70.07	4.00e-142	497.00
IUUC-Ocu-074929	Oryctolagus cuniculus	85.20	3.00e-180	624.00
IUUC-Ola-086340	Oryzias latipes	49.67	8.00e-65	241.00
IUUC-Oga-088042	Otolemur garnettii	88.07	0.00e+00	626.00
IUUC-Oar-090051	Ovis aries	92.01	2.00e-179	621.00
IUUC-Ptr-090498	Pan troglodytes	88.31	1.00e-161	562.00
IUUC-Psi-093840	Pelodiscus sinensis	56.88	6.00e-84	304.00
IUUC-Pfo-097140	Poecilia formosa	43.40	2.00e-52	199.00
IUUC-Pab-097707	Pongo abelii	89.50	5.00e-165	573.00
IUUC-Pca-100427	Procavia capensis	73.99	6.00e-126	443.00
IUUC-Pva-102328	Pteropus vampyrus	84.01	7.00e-149	520.00
IUUC-Ptt-103739	Puccinia triticina	25.40	1.10e+00	28.10
IUUC-Rno-105231	Rattus norvegicus	85.44	1.00e-178	618.00
IUUC-Sha-106676	Sarcophilus harrisii	73.71	2.00e-155	541.00
IUUC-Sar-113027	Sorex araneus	78.92	6.00e-72	263.00
IUUC-Tru-117790	Takifugu rubripes	46.10	6.00e-53	201.00
IUUC-Tbe-127949	Tupaia belangeri	90.82	2.00e-67	249.00
IUUC-Ttr-128663	Tursiops truncatus	91.40	5.00e-173	600.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence