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Tag Content
iUUCD ID IUUC-Ont-071765
Ensembl Protein ID ENSONIP00000009725.1
UniProt Accession I3JLI1; I3JLI1_ORENI
Genbank Protein ID ENSONIP00000009725
Protein Name Eukaryotic translation initiation factor 3 subunit I; Eukaryotic translation initiation factor 3 subunit 2; eIF-3-beta; eIF3 p36
Genbank Nucleotide ID AERX01010755
Gene Name eif3i; EIF3I; EIF3S2
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSONIG00000007716.1 ENSONIT00000009731.1 ENSONIP00000009725.1
Status Unreviewed
Classification
Family E-Value Score Start End
E3 adaptor/Cullin RING/DCX/DWD 2.00e-19 69.3 50 87
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtcl..afsd.tllvsGsdDgtikvWDlrtgvll 36
    gHt+ v+c+ ++ d + +++Gs D+++++WD tg++l
   Q: 50 GHTGAVWCVdcDW-DtKNVLTGSADNSCRLWDCETGKQL 87
    8*******74367.4488*****************9986 PP
   

Organism Oreochromis niloticus
Functional Description
(View)

Functional Description



     Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
Protein Sequence
(Fasta)
MKPILLQGHE RSITQIKYNR EGDLLFSVAK DTVTNVWYSV NGERLGTYNG HTGAVWCVDC 60
DWDTKNVLTG SADNSCRLWD CETGKQLALL NTNSAVRTCG FDFSGNIIMF STDKQMGYQC 120
It may take some time, please wait.

Protein Fasta Sequence



>IUUC-Ont-071765|E3,WD_repeat|Oreochromis niloticus
Please wait for a moment...
Nucleotide Sequence
(Fasta)
AAAGAATTTA ATCAGACTGG AGCCAAAATA TCAATAACAT TTTCAGAAAA TAATCTCGAA 60
CACATATGGA GACAAATATG TTGGAATAAT TGTGTTTAAA AAAGATAAAC AAGAGGGGTT 120
It may take some time, please wait.

Nucleotide Fasta Sequence



>IUUC-Ont-071765|E3,WD_repeat|Oreochromis niloticus
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0396--Initiation factor
KW-0648--Protein biosynthesis
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR027525--eIF3i
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0016282--C:eukaryotic 43S preinitiation complex
GO:0033290--C:eukaryotic 48S preinitiation complex
GO:0005852--C:eukaryotic translation initiation factor 3 complex
GO:0003743--F:translation initiation factor activity
GO:0001731--P:formation of translation preinitiation complex
GO:0001889--P:liver development
GO:0006446--P:regulation of translational initiation
GO:0002040--P:sprouting angiogenesis

Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ata-000115 Aegilops tauschii 58.41 2.00e-35 143.00
IUUC-Aml-001321 Ailuropoda melanoleuca 84.57 1.00e-171 595.00
IUUC-Atr-002468 Amborella trichopoda 49.27 1.00e-54 206.00
IUUC-Apl-003841 Anas platyrhynchos 86.42 1.00e-175 608.00
IUUC-Aca-005123 Anolis carolinensis 85.54 4.00e-175 607.00
IUUC-Aly-006532 Arabidopsis lyrata 47.26 2.00e-87 315.00
IUUC-Ath-007094 Arabidopsis thaliana 46.65 1.00e-88 319.00
IUUC-Ago-008000 Ashbya gossypii 42.90 4.00e-82 298.00
IUUC-Acl-008098 Aspergillus clavatus 51.20 1.00e-98 352.00
IUUC-Afl-008494 Aspergillus flavus 50.76 5.00e-99 354.00
IUUC-Afu-009080 Aspergillus fumigatus 50.90 7.00e-99 353.00
IUUC-Ani-009230 Aspergillus nidulans 50.91 5.00e-98 350.00
IUUC-Aor-010114 Aspergillus oryzae 50.76 5.00e-99 354.00
IUUC-Ate-010285 Aspergillus terreus 52.13 7.00e-101 360.00
IUUC-Ame-011534 Astyanax mexicanus 91.74 0.00e+00 639.00
IUUC-Bgr-012121 Blumeria graminis 47.42 8.00e-89 320.00
IUUC-Bta-013143 Bos taurus 84.62 2.00e-172 597.00
IUUC-Bci-013950 Botrytis cinerea 50.76 1.00e-97 350.00
IUUC-Bdi-015019 Brachypodium distachyon 47.24 1.00e-89 323.00
IUUC-Bol-015709 Brassica oleracea 45.15 5.00e-84 305.00
IUUC-Bra-017760 Brassica rapa 45.15 2.00e-84 306.00
IUUC-Cel-018226 Caenorhabditis elegans 43.65 9.00e-82 296.00
IUUC-Cja-019741 Callithrix jacchus 84.62 1.00e-172 598.00
IUUC-Cfa-021204 Canis familiaris 84.26 2.00e-171 595.00
IUUC-Cpo-021661 Cavia porcellus 84.88 4.00e-172 597.00
IUUC-Cre-022952 Chlamydomonas reinhardtii 44.89 2.00e-81 296.00
IUUC-Csa-024038 Chlorocebus sabaeus 84.62 1.00e-172 598.00
IUUC-Cin-025597 Ciona intestinalis 58.46 3.00e-117 414.00
IUUC-Cgl-026583 Colletotrichum gloeosporioides 49.39 1.00e-92 333.00
IUUC-Cne-026838 Cryptococcus neoformans 47.40 3.00e-91 328.00
IUUC-Cme-027304 Cyanidioschyzon merolae 45.79 9.00e-84 303.00
IUUC-Dre-028567 Danio rerio 93.23 0.00e+00 649.00
IUUC-Dno-029171 Dasypus novemcinctus 84.88 2.00e-172 598.00
IUUC-Dor-030257 Dipodomys ordii 73.30 1.00e-75 276.00
IUUC-Dse-031191 Dothistroma septosporum 49.54 3.00e-93 335.00
IUUC-Dme-031879 Drosophila melanogaster 60.56 4.00e-120 424.00
IUUC-Ete-032336 Echinops telfairi 80.37 4.00e-106 377.00
IUUC-Eca-033259 Equus caballus 84.57 8.00e-172 596.00
IUUC-Eeu-035153 Erinaceus europaeus 64.43 3.00e-50 192.00
IUUC-Fca-036489 Felis catus 84.57 8.00e-172 596.00
IUUC-Fal-037485 Ficedula albicollis 87.04 1.00e-176 612.00
IUUC-Fox-037860 Fusarium oxysporum 48.01 5.00e-92 331.00
IUUC-Fso-038188 Fusarium solani 48.93 9.00e-92 330.00
IUUC-Gmo-039311 Gadus morhua 94.14 0.00e+00 652.00
IUUC-Ggr-040045 Gaeumannomyces graminis 49.54 2.00e-95 342.00
IUUC-Gga-040645 Gallus gallus 84.38 2.00e-174 604.00
IUUC-Gac-042086 Gasterosteus aculeatus 95.38 0.00e+00 657.00
IUUC-Gma-043246 Glycine max 46.01 1.00e-89 322.00
IUUC-Ggo-045578 Gorilla gorilla 84.62 1.00e-172 598.00
IUUC-Hsa-046734 Homo sapiens 84.62 1.00e-172 598.00
IUUC-Hvu-047553 Hordeum vulgare 46.63 2.00e-89 322.00
IUUC-Itr-048467 Ictidomys tridecemlineatus 84.26 2.00e-171 595.00
IUUC-Kpa-049325 Komagataella pastoris 44.79 5.00e-87 314.00
IUUC-Lch-049620 Latimeria chalumnae 84.23 5.00e-158 550.00
IUUC-Lpe-051338 Leersia perrieri 45.34 2.00e-81 296.00
IUUC-Loc-052094 Lepisosteus oculatus 85.76 3.00e-168 584.00
IUUC-Lma-053047 Leptosphaeria maculans 48.02 3.00e-92 332.00
IUUC-Laf-053801 Loxodonta africana 84.28 4.00e-168 583.00
IUUC-Mcc-055498 Macaca mulatta 74.46 8.00e-143 499.00
IUUC-Meu-056729 Macropus eugenii 78.22 2.00e-156 544.00
IUUC-Mor-057025 Magnaporthe oryzae 49.85 8.00e-94 337.00
IUUC-Mpo-057511 Magnaporthe poae 50.15 7.00e-95 340.00
IUUC-Mtr-058051 Medicago truncatula 46.32 2.00e-89 322.00
IUUC-Mla-059061 Melampsora laricipopulina 46.42 4.00e-85 308.00
IUUC-Mga-059229 Meleagris gallopavo 85.58 3.00e-173 600.00
IUUC-Mvi-060399 Microbotryum violaceum 45.48 1.00e-81 296.00
IUUC-Mmr-060764 Microcebus murinus 84.92 4.00e-173 600.00
IUUC-Mdo-062088 Monodelphis domestica 84.92 1.00e-172 598.00
IUUC-Mmu-064304 Mus musculus 84.92 9.00e-173 599.00
IUUC-Mac-065520 Musa acuminata 48.45 1.00e-91 329.00
IUUC-Mpu-066340 Mustela putorius furo 84.57 8.00e-172 596.00
IUUC-Mlu-067111 Myotis lucifugus 84.57 4.00e-172 597.00
IUUC-Nfi-068478 Neosartorya fischeri 50.90 1.00e-98 352.00
IUUC-Ncr-068820 Neurospora crassa 50.00 3.00e-94 338.00
IUUC-Nle-069903 Nomascus leucogenys 84.57 3.00e-172 597.00
IUUC-Opr-070221 Ochotona princeps 82.46 7.00e-167 579.00
IUUC-Oan-073660 Ornithorhynchus anatinus 84.69 1.00e-156 545.00
IUUC-Ocu-074039 Oryctolagus cuniculus 84.57 5.00e-172 596.00
IUUC-Oba-075395 Oryza barthii 39.88 2.00e-71 262.00
IUUC-Obr-076334 Oryza brachyantha 43.25 9.00e-81 293.00
IUUC-Ogl-077751 Oryza glaberrima 46.01 8.00e-88 317.00
IUUC-Ogu-078207 Oryza glumaepatula 46.15 2.00e-87 316.00
IUUC-Oin-079878 Oryza indica 46.32 4.00e-88 317.00
IUUC-Olo-080677 Oryza longistaminata 39.47 8.00e-79 287.00
IUUC-Ome-081228 Oryza meridionalis 34.96 8.00e-35 140.00
IUUC-Oni-082411 Oryza nivara 40.30 3.00e-71 261.00
IUUC-Opu-083136 Oryza punctata 46.01 1.00e-87 316.00
IUUC-Oru-084916 Oryza rufipogon 45.07 1.00e-85 309.00
IUUC-Osa-085454 Oryza sativa 46.32 4.00e-88 317.00
IUUC-Ola-087053 Oryzias latipes 93.54 0.00e+00 649.00
IUUC-Olu-087602 Ostreococcus lucimarinus 46.58 4.00e-88 317.00
IUUC-Oga-088154 Otolemur garnettii 84.26 4.00e-171 593.00
IUUC-Oar-089915 Ovis aries 84.57 1.00e-171 595.00
IUUC-Ptr-091124 Pan troglodytes 67.50 3.00e-126 444.00
IUUC-Pan-092035 Papio anubis 84.62 1.00e-172 598.00
IUUC-Psi-094096 Pelodiscus sinensis 81.57 1.00e-109 389.00
IUUC-Pno-094988 Phaeosphaeria nodorum 45.09 3.00e-82 298.00
IUUC-Ppa-095949 Physcomitrella patens 49.08 1.00e-94 339.00
IUUC-Pfo-096101 Poecilia formosa 95.38 0.00e+00 660.00
IUUC-Pab-097726 Pongo abelii 84.62 1.00e-172 598.00
IUUC-Pop-099617 Populus trichocarpa 47.85 7.00e-92 330.00
IUUC-Pca-101014 Procavia capensis 84.62 2.00e-172 598.00
IUUC-Ppe-101320 Prunus persica 46.93 2.00e-88 319.00
IUUC-Pva-102789 Pteropus vampyrus 75.08 2.00e-145 508.00
IUUC-Pgr-103479 Puccinia graminis 46.42 2.00e-84 305.00
IUUC-Ptt-103981 Puccinia triticina 46.73 6.00e-86 310.00
IUUC-Pte-104278 Pyrenophora teres 48.33 2.00e-91 328.00
IUUC-Pyt-104492 Pyrenophora triticirepentis 48.33 2.00e-91 328.00
IUUC-Rno-105867 Rattus norvegicus 66.67 3.00e-123 434.00
IUUC-Sce-106251 Saccharomyces cerevisiae 44.18 3.00e-82 298.00
IUUC-Sha-107039 Sarcophilus harrisii 84.92 6.00e-173 599.00
IUUC-Sja-107758 Schizosaccharomyces japonicus 49.85 2.00e-94 339.00
IUUC-Spo-108314 Schizosaccharomyces pombe 49.54 1.00e-92 332.00
IUUC-Ssl-108478 Sclerotinia sclerotiorum 50.15 8.00e-97 347.00
IUUC-Smo-108728 Selaginella moellendorffii 48.31 1.00e-89 323.00
IUUC-Sit-110801 Setaria italica 45.71 8.00e-87 313.00
IUUC-Sly-111326 Solanum lycopersicum 47.71 5.00e-90 324.00
IUUC-Stu-112458 Solanum tuberosum 47.55 8.00e-90 323.00
IUUC-Sbi-114063 Sorghum bicolor 45.09 9.00e-86 310.00
IUUC-Sre-115096 Sporisorium reilianum 47.16 8.00e-85 307.00
IUUC-Ssc-116080 Sus scrofa 84.62 2.00e-172 597.00
IUUC-Tgu-116988 Taeniopygia guttata 87.04 3.00e-176 610.00
IUUC-Tru-118766 Takifugu rubripes 96.00 0.00e+00 665.00
IUUC-Tni-120197 Tetraodon nigroviridis 95.69 0.00e+00 664.00
IUUC-Tca-121316 Theobroma cacao 46.32 5.00e-89 321.00
IUUC-Tre-122097 Trichoderma reesei 50.30 5.00e-94 337.00
IUUC-Tvi-122442 Trichoderma virens 50.30 2.00e-94 339.00
IUUC-Tae-125800 Triticum aestivum 46.63 2.00e-89 323.00
IUUC-Tur-126334 Triticum urartu 40.49 4.00e-70 258.00
IUUC-Tme-127038 Tuber melanosporum 51.22 5.00e-100 357.00
IUUC-Ttr-128659 Tursiops truncatus 79.08 6.00e-148 516.00
IUUC-Uma-129464 Ustilago maydis 47.16 3.00e-84 305.00
IUUC-Vda-129841 Verticillium dahliae 51.68 2.00e-96 345.00
IUUC-Vvi-131076 Vitis vinifera 47.09 3.00e-90 325.00
IUUC-Xtr-132395 Xenopus tropicalis 84.92 3.00e-173 600.00
IUUC-Xma-133383 Xiphophorus maculatus 95.08 0.00e+00 658.00
IUUC-Yli-134586 Yarrowia lipolytica 48.77 2.00e-82 299.00
IUUC-Zma-135904 Zea mays 45.40 2.00e-86 312.00
Created Date 25-Jun-2017

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