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Tag Content
iUUCD ID IUUC-Oga-089006
Ensembl Protein ID ENSOGAP00000022055.1
UniProt Accession H0Y112; H0Y112_OTOGA
Genbank Protein ID ENSOGAP00000022055
Protein Name DNA repair protein REV1
Genbank Nucleotide ID AAQR03110281
Gene Name REV1
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSOGAG00000013247.2 ENSOGAT00000029956.1 ENSOGAP00000022055.1
ENSOGAG00000013247.2 ENSOGAT00000013258.2 ENSOGAP00000011876.2
Status Unreviewed
Classification
Family E-Value Score Start End
UBD/Alpha-Helix/UBM 8.50e-20 69.8 1017 1045
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   UBD/Alpha-Helix/UBM
   S: 1    lPsqvDpeVfsqLPeeiQeEvmaelrqqk 29
           ++sqvDpeVf++LP+e+Q+E++a+++ ++
   Q: 1017 AFSQVDPEVFAALPAELQKELKAAYDERQ 1045
           59***********************9876 PP
   
Organism Otolemur garnettii
Functional Description
(View)

Functional Description


     Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template-dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents.
 Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template-dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents.
Protein Sequence
(Fasta)
MRRGGWRKRA ENDGWEKWSE YMAAKVQKLE EQFRSDAAMQ KDGTSSTIFS GVAIYVNGYT 60
DPSAEELRKL MMLHGGQYHV YYSRSKTTHI IATNLPNAKI KELKGEKVIR PEWIVESIKA 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Oga-089006|UBD,UBM|Otolemur garnettii
Please wait for a moment...
Nucleotide Sequence
(Fasta)
GGACACTGTG CGGCGGCGGA GCCGGGGTCT GTGAGGCACG AGGAGGAGGC CGGGCCCGGG 60
CATGGTGGTC TGGGGCAACG CGGAAGGTGA GCGACTCCGG GGCCGGCGGC GGGGGTGGGG 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Oga-089006|UBD,UBM|Otolemur garnettii
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0227--DNA damage
KW-0234--DNA repair
KW-0237--DNA synthesis
KW-0238--DNA-binding
KW-0548--Nucleotidyltransferase
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0808--Transferase
Interpro

IPR001357--BRCT_dom
IPR017961--DNA_pol_Y-fam_little_finger
IPR025527--DUF4414
IPR012112--REV1
IPR031991--Rev1_C
IPR001126--UmuC
PROSITE

PS50172--BRCT
PS50173--UMUC
Pfam

PF16589--BRCT_2
PF14377--DUF4414
PF00817--IMS
PF11799--IMS_C
PF16727--REV1_C
SMART

SM00292--BRCT
Gene Ontology

GO:0005634--C:nucleus
GO:0003684--F:damaged DNA binding
GO:0017125--F:deoxycytidyl transferase activity
GO:0042276--P:error-prone translesion synthesis
GO:0009411--P:response to UV
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ata-000375 Aegilops tauschii 29.69 9.00e-32 132.00
IUUC-Aml-001185 Ailuropoda melanoleuca 88.00 0.00e+00 2167.00
IUUC-Atr-002915 Amborella trichopoda 28.93 2.00e-104 374.00
IUUC-Apl-004054 Anas platyrhynchos 75.65 0.00e+00 1823.00
IUUC-Aca-004304 Anolis carolinensis 68.75 0.00e+00 1664.00
IUUC-Aly-005696 Arabidopsis lyrata 34.05 9.00e-83 301.00
IUUC-Ath-006893 Arabidopsis thaliana 34.77 2.00e-83 303.00
IUUC-Ago-007722 Ashbya gossypii 31.81 3.00e-34 140.00
IUUC-Acl-008347 Aspergillus clavatus 37.24 7.00e-77 282.00
IUUC-Afl-008444 Aspergillus flavus 36.18 3.00e-83 303.00
IUUC-Afu-008837 Aspergillus fumigatus 34.48 1.00e-78 288.00
IUUC-Ani-009188 Aspergillus nidulans 45.10 2.00e-81 297.00
IUUC-Ang-009866 Aspergillus niger 36.12 1.00e-85 311.00
IUUC-Aor-010107 Aspergillus oryzae 36.18 3.00e-83 303.00
IUUC-Ate-010359 Aspergillus terreus 35.18 8.00e-81 295.00
IUUC-Ame-010664 Astyanax mexicanus 49.41 0.00e+00 1109.00
IUUC-Bgr-012244 Blumeria graminis 31.28 3.00e-81 296.00
IUUC-Bta-013405 Bos taurus 80.89 0.00e+00 1822.00
IUUC-Bci-013849 Botrytis cinerea 35.04 8.00e-81 295.00
IUUC-Bdi-014066 Brachypodium distachyon 36.33 5.00e-84 306.00
IUUC-Bol-015544 Brassica oleracea 35.69 1.00e-88 321.00
IUUC-Bra-017792 Brassica rapa 34.29 7.00e-83 302.00
IUUC-Cel-018148 Caenorhabditis elegans 34.62 5.00e-76 279.00
IUUC-Cja-019742 Callithrix jacchus 77.93 0.00e+00 1567.00
IUUC-Cfa-020112 Canis familiaris 88.40 0.00e+00 2178.00
IUUC-Cpo-022152 Cavia porcellus 84.43 0.00e+00 2138.00
IUUC-Cre-022951 Chlamydomonas reinhardtii 42.15 6.00e-41 162.00
IUUC-Csa-023504 Chlorocebus sabaeus 89.67 0.00e+00 2237.00
IUUC-Cho-024780 Choloepus hoffmanni 66.79 0.00e+00 733.00
IUUC-Cin-025276 Ciona intestinalis 42.65 3.00e-112 399.00
IUUC-Csv-026283 Ciona savignyi 44.88 1.00e-116 413.00
IUUC-Cgl-026726 Colletotrichum gloeosporioides 30.12 2.00e-80 294.00
IUUC-Cne-027079 Cryptococcus neoformans 33.79 1.00e-77 285.00
IUUC-Cme-027346 Cyanidioschyzon merolae 27.34 8.00e-42 166.00
IUUC-Dre-028073 Danio rerio 49.89 0.00e+00 1103.00
IUUC-Dno-030038 Dasypus novemcinctus 82.35 0.00e+00 2020.00
IUUC-Dor-031100 Dipodomys ordii 83.55 0.00e+00 1536.00
IUUC-Dse-031310 Dothistroma septosporum 32.42 6.00e-76 279.00
IUUC-Dme-031991 Drosophila melanogaster 41.57 1.00e-110 394.00
IUUC-Ete-033082 Echinops telfairi 76.74 0.00e+00 1426.00
IUUC-Eca-033471 Equus caballus 87.61 0.00e+00 2149.00
IUUC-Eeu-034993 Erinaceus europaeus 84.61 0.00e+00 1417.00
IUUC-Fca-035367 Felis catus 88.18 0.00e+00 2108.00
IUUC-Fal-036973 Ficedula albicollis 75.14 0.00e+00 1743.00
IUUC-Fox-037677 Fusarium oxysporum 33.62 8.00e-80 291.00
IUUC-Fso-038252 Fusarium solani 35.36 1.00e-81 298.00
IUUC-Gmo-039669 Gadus morhua 51.61 0.00e+00 814.00
IUUC-Ggr-039988 Gaeumannomyces graminis 32.49 2.00e-74 274.00
IUUC-Gga-040423 Gallus gallus 75.81 0.00e+00 1810.00
IUUC-Gac-042134 Gasterosteus aculeatus 47.94 0.00e+00 980.00
IUUC-Gma-042929 Glycine max 34.78 1.00e-83 305.00
IUUC-Ggo-044528 Gorilla gorilla 90.79 0.00e+00 2241.00
IUUC-Hsa-046259 Homo sapiens 90.47 0.00e+00 2206.00
IUUC-Hvu-047139 Hordeum vulgare 34.63 2.00e-53 203.00
IUUC-Itr-048621 Ictidomys tridecemlineatus 88.07 0.00e+00 2194.00
IUUC-Kpa-049169 Komagataella pastoris 29.55 2.00e-61 231.00
IUUC-Lch-050471 Latimeria chalumnae 64.93 0.00e+00 1536.00
IUUC-Lpe-050800 Leersia perrieri 33.96 5.00e-88 319.00
IUUC-Loc-052320 Lepisosteus oculatus 47.44 0.00e+00 954.00
IUUC-Lma-053149 Leptosphaeria maculans 33.33 2.00e-82 300.00
IUUC-Laf-053810 Loxodonta africana 82.67 0.00e+00 1976.00
IUUC-Mcc-055574 Macaca mulatta 89.99 0.00e+00 2185.00
IUUC-Meu-055945 Macropus eugenii 66.03 0.00e+00 1157.00
IUUC-Mor-057195 Magnaporthe oryzae 28.11 4.00e-106 379.00
IUUC-Mpo-057488 Magnaporthe poae 35.37 5.00e-76 279.00
IUUC-Mtr-057955 Medicago truncatula 43.89 3.00e-80 293.00
IUUC-Mla-059027 Melampsora laricipopulina 36.24 3.00e-79 289.00
IUUC-Mga-060156 Meleagris gallopavo 75.97 0.00e+00 1825.00
IUUC-Mvi-060398 Microbotryum violaceum 36.18 3.00e-82 300.00
IUUC-Mmr-061113 Microcebus murinus 93.01 0.00e+00 2258.00
IUUC-Mdo-063001 Monodelphis domestica 82.01 0.00e+00 1984.00
IUUC-Mmu-063180 Mus musculus 82.54 0.00e+00 2026.00
IUUC-Mac-065551 Musa acuminata 38.87 5.00e-54 206.00
IUUC-Mpu-066525 Mustela putorius furo 88.72 0.00e+00 2169.00
IUUC-Mlu-067877 Myotis lucifugus 86.02 0.00e+00 2105.00
IUUC-Nfi-068418 Neosartorya fischeri 34.21 2.00e-79 290.00
IUUC-Ncr-068648 Neurospora crassa 35.99 1.00e-82 301.00
IUUC-Nle-069959 Nomascus leucogenys 90.31 0.00e+00 2210.00
IUUC-Opr-070522 Ochotona princeps 81.87 0.00e+00 1173.00
IUUC-Ont-072293 Oreochromis niloticus 45.03 0.00e+00 808.00
IUUC-Oan-073519 Ornithorhynchus anatinus 78.75 0.00e+00 1915.00
IUUC-Ocu-074492 Oryctolagus cuniculus 84.06 0.00e+00 1957.00
IUUC-Oba-075567 Oryza barthii 33.02 3.00e-88 320.00
IUUC-Obr-076332 Oryza brachyantha 36.53 6.00e-85 309.00
IUUC-Ogl-077348 Oryza glaberrima 33.02 5.00e-88 319.00
IUUC-Ogu-078779 Oryza glumaepatula 30.19 1.00e-113 404.00
IUUC-Oin-079738 Oryza indica 30.85 4.00e-76 280.00
IUUC-Olo-080701 Oryza longistaminata 30.85 2.00e-76 280.00
IUUC-Ome-081708 Oryza meridionalis 29.15 4.00e-86 313.00
IUUC-Oni-082251 Oryza nivara 32.75 4.00e-85 310.00
IUUC-Opu-083528 Oryza punctata 31.09 6.00e-81 295.00
IUUC-Oru-084293 Oryza rufipogon 32.28 9.00e-83 301.00
IUUC-Osa-085549 Oryza sativa 32.81 9.00e-88 318.00
IUUC-Ola-086793 Oryzias latipes 50.10 0.00e+00 833.00
IUUC-Olu-087786 Ostreococcus lucimarinus 29.43 3.00e-61 229.00
IUUC-Oar-089597 Ovis aries 82.05 0.00e+00 1989.00
IUUC-Ptr-091520 Pan troglodytes 90.47 0.00e+00 2206.00
IUUC-Pan-092333 Papio anubis 89.83 0.00e+00 2164.00
IUUC-Psi-094004 Pelodiscus sinensis 77.95 0.00e+00 1880.00
IUUC-Pma-094128 Petromyzon marinus 52.38 1.00e-91 330.00
IUUC-Pno-094849 Phaeosphaeria nodorum 32.38 5.00e-70 259.00
IUUC-Ppa-095714 Physcomitrella patens 29.66 1.00e-85 311.00
IUUC-Pfo-096569 Poecilia formosa 46.75 0.00e+00 983.00
IUUC-Pab-097960 Pongo abelii 89.99 0.00e+00 2197.00
IUUC-Pop-098921 Populus trichocarpa 36.98 7.00e-85 309.00
IUUC-Pca-100509 Procavia capensis 67.90 0.00e+00 1174.00
IUUC-Ppe-101730 Prunus persica 30.56 1.00e-87 318.00
IUUC-Pva-102142 Pteropus vampyrus 84.83 0.00e+00 2063.00
IUUC-Pgr-103446 Puccinia graminis 30.26 2.00e-67 250.00
IUUC-Ptt-103849 Puccinia triticina 30.17 2.00e-72 268.00
IUUC-Pte-104128 Pyrenophora teres 32.98 1.00e-75 278.00
IUUC-Pyt-104754 Pyrenophora triticirepentis 36.31 3.00e-75 276.00
IUUC-Rno-104871 Rattus norvegicus 80.41 0.00e+00 1981.00
IUUC-Sce-106236 Saccharomyces cerevisiae 27.29 4.00e-39 157.00
IUUC-Sha-106962 Sarcophilus harrisii 81.66 0.00e+00 1959.00
IUUC-Sja-107691 Schizosaccharomyces japonicus 28.31 2.00e-63 238.00
IUUC-Spo-108170 Schizosaccharomyces pombe 30.19 2.00e-63 237.00
IUUC-Ssl-108668 Sclerotinia sclerotiorum 34.71 2.00e-82 301.00
IUUC-Smo-109554 Selaginella moellendorffii 36.08 4.00e-79 290.00
IUUC-Sit-110479 Setaria italica 35.49 7.00e-72 265.00
IUUC-Sly-111752 Solanum lycopersicum 34.36 1.00e-88 321.00
IUUC-Sar-113304 Sorex araneus 85.19 0.00e+00 2032.00
IUUC-Sbi-114196 Sorghum bicolor 35.56 2.00e-72 267.00
IUUC-Sre-115151 Sporisorium reilianum 30.93 6.00e-85 309.00
IUUC-Ssc-116104 Sus scrofa 85.69 0.00e+00 2102.00
IUUC-Tgu-117438 Taeniopygia guttata 76.36 0.00e+00 1808.00
IUUC-Tru-118553 Takifugu rubripes 47.42 0.00e+00 993.00
IUUC-Tsy-119056 Tarsius syrichta 85.17 0.00e+00 2013.00
IUUC-Tni-119933 Tetraodon nigroviridis 46.70 0.00e+00 933.00
IUUC-Tca-121376 Theobroma cacao 32.03 5.00e-113 402.00
IUUC-Tre-121972 Trichoderma reesei 34.12 4.00e-74 273.00
IUUC-Tvi-122342 Trichoderma virens 34.17 2.00e-72 268.00
IUUC-Tae-123898 Triticum aestivum 29.57 1.00e-103 370.00
IUUC-Tur-126735 Triticum urartu 29.08 1.00e-35 145.00
IUUC-Tme-126999 Tuber melanosporum 32.87 7.00e-81 296.00
IUUC-Tbe-127280 Tupaia belangeri 87.30 2.00e-140 493.00
IUUC-Ttr-129104 Tursiops truncatus 85.79 0.00e+00 2071.00
IUUC-Uma-129562 Ustilago maydis 30.72 4.00e-86 313.00
IUUC-Vda-129862 Verticillium dahliae 33.57 2.00e-81 297.00
IUUC-Vpa-130819 Vicugna pacos 83.21 0.00e+00 1098.00
IUUC-Vvi-131111 Vitis vinifera 34.56 5.00e-81 296.00
IUUC-Xtr-132629 Xenopus tropicalis 61.56 0.00e+00 1409.00
IUUC-Xma-134065 Xiphophorus maculatus 44.73 0.00e+00 808.00
IUUC-Yli-134633 Yarrowia lipolytica 32.62 1.00e-62 235.00
IUUC-Zma-135176 Zea mays 36.25 3.00e-83 303.00
Created Date 25-Jun-2017

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