iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Bta-012442

Ensembl Protein ID

ENSBTAP00000056302.1

UniProt Accession

Q58CQ2; Q0V8Q8; Q58DS1; ARC1B_BOVIN

Genbank Protein ID

AAX46373.1; AAX46742.1; ABG66999.1; AAI02943.1

Protein Name

Actin-related protein 2/3 complex subunit 1B; Arp2/3 complex 41 kDa subunit; p41-ARC

Genbank Nucleotide ID

BT021526; BT021895; BT026160; BC102942

Gene Name

ARPC1B

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSBTAG00000046248.1	ENSBTAT00000064158.1	ENSBTAP00000056302.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	6.00e-16	58.1	51	80

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sd.tllvsGsdDgtikvWD 29
           H++ vt++++ +d +++v+++ D + +vW 
   Q: 51   HNGQVTGIDWaPDsNRIVTCGTDRNAYVWT 80
           9**********999***************6 PP

Organism

Bos taurus

Functional Description
(View)

Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.

Protein Sequence
(Fasta)

MAYHSFLVEP ISCHAWNKDR TQIAICPNNH EVHIYEKSGN KWVQVHELKE HNGQVTGIDW 60
APDSNRIVTC GTDRNAYVWT LKGRTWKPTL VILRINRAAR CVRWAPNEKK FAVGSGSRVI 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGCGCGTCGA CTGCCCAGAG TCCGCGGCCG CGGCGCCCCG AGGTGAGGGG GGCGCGGGGG 60
CAGCCCGGAA GGGCGGGATC GAGGGGAGCG CGGGGAGGGG GCGCGTGCAG GTGGGGAGGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0002--3D-structure
KW-0007--Acetylation
KW-0009--Actin-binding
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0206--Cytoskeleton
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR030141--ARC1B
IPR017383--ARPC1
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom

PROSITE

PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0005885--C:Arp2/3 protein complex
GO:0005829--C:cytosol
GO:0070062--C:extracellular exosome
GO:0005925--C:focal adhesion
GO:0051015--F:actin filament binding
GO:0005200--F:structural constituent of cytoskeleton
GO:0034314--P:Arp2/3 complex-mediated actin nucleation

KEGG

bta:326600

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000669	Aegilops tauschii	43.77	2.00e-62	233.00
IUUC-Aml-001709	Ailuropoda melanoleuca	94.40	0.00e+00	714.00
IUUC-Ath-006683	Arabidopsis thaliana	41.67	8.00e-79	287.00
IUUC-Ame-011512	Astyanax mexicanus	79.30	0.00e+00	649.00
IUUC-Cja-019899	Callithrix jacchus	94.89	0.00e+00	738.00
IUUC-Cfa-020067	Canis familiaris	94.88	0.00e+00	716.00
IUUC-Cpo-022461	Cavia porcellus	96.23	0.00e+00	724.00
IUUC-Cre-022590	Chlamydomonas reinhardtii	34.69	2.00e-34	138.00
IUUC-Csa-023277	Chlorocebus sabaeus	87.60	0.00e+00	677.00
IUUC-Dre-028141	Danio rerio	79.84	0.00e+00	644.00
IUUC-Dor-030559	Dipodomys ordii	94.07	0.00e+00	719.00
IUUC-Ete-032299	Echinops telfairi	92.99	0.00e+00	728.00
IUUC-Eca-033593	Equus caballus	93.82	0.00e+00	711.00
IUUC-Fca-036254	Felis catus	96.23	0.00e+00	725.00
IUUC-Fal-037453	Ficedula albicollis	86.86	0.00e+00	683.00
IUUC-Gmo-038471	Gadus morhua	69.25	4.00e-161	560.00
IUUC-Gga-040898	Gallus gallus	86.79	0.00e+00	688.00
IUUC-Gac-042236	Gasterosteus aculeatus	73.82	2.00e-175	607.00
IUUC-Ggo-045355	Gorilla gorilla	79.57	5.00e-165	573.00
IUUC-Hsa-046623	Homo sapiens	95.96	0.00e+00	724.00
IUUC-Itr-048596	Ictidomys tridecemlineatus	95.42	0.00e+00	727.00
IUUC-Lch-049679	Latimeria chalumnae	77.90	0.00e+00	628.00
IUUC-Loc-052140	Lepisosteus oculatus	79.03	3.00e-180	624.00
IUUC-Laf-054287	Loxodonta africana	91.73	0.00e+00	682.00
IUUC-Meu-056302	Macropus eugenii	88.68	0.00e+00	698.00
IUUC-Mga-059279	Meleagris gallopavo	86.79	0.00e+00	689.00
IUUC-Mmr-060752	Microcebus murinus	95.29	0.00e+00	712.00
IUUC-Mdo-062836	Monodelphis domestica	85.44	0.00e+00	662.00
IUUC-Mmu-064099	Mus musculus	94.67	0.00e+00	714.00
IUUC-Mpu-066247	Mustela putorius furo	94.88	0.00e+00	701.00
IUUC-Mlu-067571	Myotis lucifugus	95.15	0.00e+00	736.00
IUUC-Nle-069492	Nomascus leucogenys	82.48	4.00e-169	587.00
IUUC-Ont-071316	Oreochromis niloticus	74.61	7.00e-174	602.00
IUUC-Oan-072692	Ornithorhynchus anatinus	86.52	0.00e+00	687.00
IUUC-Ocu-074187	Oryctolagus cuniculus	91.11	0.00e+00	700.00
IUUC-Oba-075379	Oryza barthii	40.55	5.00e-77	281.00
IUUC-Ogl-077409	Oryza glaberrima	38.42	1.00e-71	263.00
IUUC-Ogu-078759	Oryza glumaepatula	40.55	6.00e-77	281.00
IUUC-Oin-079118	Oryza indica	40.60	1.00e-77	283.00
IUUC-Olo-081055	Oryza longistaminata	39.82	8.00e-68	250.00
IUUC-Oni-083043	Oryza nivara	40.55	5.00e-77	281.00
IUUC-Oru-084839	Oryza rufipogon	40.55	5.00e-77	281.00
IUUC-Osa-085377	Oryza sativa	40.60	1.00e-77	283.00
IUUC-Oga-088610	Otolemur garnettii	95.69	0.00e+00	723.00
IUUC-Oar-089639	Ovis aries	95.43	0.00e+00	711.00
IUUC-Ptr-091023	Pan troglodytes	95.69	0.00e+00	721.00
IUUC-Pan-091727	Papio anubis	95.42	0.00e+00	730.00
IUUC-Pfo-097058	Poecilia formosa	73.30	1.00e-174	605.00
IUUC-Pab-098238	Pongo abelii	95.69	0.00e+00	728.00
IUUC-Pca-100580	Procavia capensis	92.99	0.00e+00	700.00
IUUC-Pva-102928	Pteropus vampyrus	92.72	0.00e+00	687.00
IUUC-Rno-104846	Rattus norvegicus	95.42	0.00e+00	719.00
IUUC-Sly-111048	Solanum lycopersicum	41.78	1.00e-76	279.00
IUUC-Sar-113404	Sorex araneus	76.50	9.00e-154	536.00
IUUC-Sbi-114685	Sorghum bicolor	40.71	9.00e-77	280.00
IUUC-Tru-118106	Takifugu rubripes	73.49	1.00e-176	612.00
IUUC-Tni-120079	Tetraodon nigroviridis	74.80	3.00e-178	617.00
IUUC-Tur-126640	Triticum urartu	38.67	2.00e-67	249.00
IUUC-Ttr-128698	Tursiops truncatus	96.23	0.00e+00	728.00
IUUC-Vvi-131647	Vitis vinifera	41.22	7.00e-79	287.00
IUUC-Xtr-131893	Xenopus tropicalis	81.94	0.00e+00	652.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence