iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Vvi-131451

Ensembl Protein ID

VIT_06s0004g01130.t01

UniProt Accession

D7SLE4; D7SLE4_VITVI

Genbank Protein ID

CBI16472.3

Protein Name

E3 ubiquitin-protein ligase

Genbank Nucleotide ID

FN594951

Gene Name

VIT_06s0004g01130

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
VIT_06s0004g01130	VIT_06s0004g01130.t01	VIT_06s0004g01130.t01

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	37.40	9.00e-40	160.00	IUUC-Dme-031755

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Vitis vinifera

Functional Description
(View)

E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.

Protein Sequence
(Fasta)

MAPGGGICKE VCESRSAFAD YDVTTANLEL RSSPFRKATT GVGGKHGMPS TSGVHELLEC 60
PVCMDLMHPP IHQCPNGHTL CSNCKARVHN CCPTCRFELG NIRCLALEKI AESLELPCRY 120

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Nucleotide Sequence
(Fasta)

TGAACAGAGA TGGCTCCAGG AGGTGGCATC TGCAAGGAAG TTTGCGAGTC CCGCTCTGCA 60
TTTGCAGACT ATGATGTAAC AACAGCAAAT TTGGAACTAA GAAGTTCTCC TTTCAGAAAA 120

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Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR018121--7-in-absentia-prot_TRAF-dom
IPR004162--SINA-like
IPR008974--TRAF-like
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR013010--Znf_SIAH

PROSITE

PS50089--ZF_RING_2
PS51081--ZF_SIAH

Pfam

PF03145--Sina

Gene Ontology

GO:0005634--C:nucleus
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0007275--P:multicellular organism development
GO:0006511--P:ubiquitin-dependent protein catabolic process

KEGG

vvi:100267231

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ame-011196	Astyanax mexicanus	37.86	3.00e-42	164.00
IUUC-Cel-018320	Caenorhabditis elegans	33.99	7.00e-36	143.00
IUUC-Cin-025674	Ciona intestinalis	33.71	2.00e-41	161.00
IUUC-Csv-026233	Ciona savignyi	34.82	3.00e-41	160.00
IUUC-Dre-028041	Danio rerio	37.86	3.00e-42	164.00
IUUC-Dme-031755	Drosophila melanogaster	37.40	4.00e-41	160.00
IUUC-Gac-042282	Gasterosteus aculeatus	37.86	3.00e-42	164.00
IUUC-Mmu-063876	Mus musculus	37.45	4.00e-42	163.00
IUUC-Ont-071849	Oreochromis niloticus	37.86	3.00e-42	164.00
IUUC-Ola-086814	Oryzias latipes	37.86	3.00e-42	164.00
IUUC-Pfo-097134	Poecilia formosa	37.86	3.00e-42	164.00
IUUC-Pop-099563	Populus trichocarpa	77.17	1.00e-145	508.00
IUUC-Ppe-101760	Prunus persica	79.55	2.00e-153	533.00
IUUC-Sly-111117	Solanum lycopersicum	76.22	6.00e-147	512.00
IUUC-Stu-112714	Solanum tuberosum	75.73	4.00e-145	506.00
IUUC-Tru-118250	Takifugu rubripes	36.36	1.00e-40	158.00
IUUC-Tni-120488	Tetraodon nigroviridis	37.55	2.00e-39	155.00
IUUC-Ttr-129166	Tursiops truncatus	37.34	1.00e-39	155.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence