iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ang-009737

Ensembl Protein ID

CAK42555

UniProt Accession

A2R5Y8; A2R5Y8_ASPNC

Genbank Protein ID

CAK42555.1

Protein Name

Aspergillus niger contig An15c0200, genomic contig

Genbank Nucleotide ID

AM270347

Gene Name

An15g06020

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
An15g06020	CAK42555	CAK42555

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E1	2.10e-197	655.8	422	909

Active Site

Position(s)	Description	Evidence
605	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU10132}

Domain Profile

   S: 1    YDRQirlwGeeaqeklksakvllvGagglGcEllKnLvlaGv.....gsitvvDmdtvevsnlnrqFLfraedvgksKAevaaealkelnpdvnveahe.. 94
           YD+Qi+++G e q+k+ + + +lvGag++GcE+lKn +++G+     g+i v+Dmd++e+snlnrqFLfr +dvgk K+e+a +a++ +np  n+++++  
   Q: 422  YDGQIAVFGKEFQDKIANVRQFLVGAGAIGCETLKNWAMMGLgtgpkGKIIVTDMDQIEKSNLNRQFLFRSRDVGKLKSECASAAVQAMNPELNGKIVTlr 522
           *********************************************************************************************99887633 PP
   S: 95   esiteleeeiv...FfkkfdvVvlaldnrearrkvnrlclnarvpliesgtlGllGqvrviikgltecyscsddppqktiPfctlketpnaaehtiewa.. 190
           +++ +++e+++   F +++d+V +aldn++ar++v+r+c+  r+pl+esgtlG++G+++v+++ +te+ys+s+dpp+kt+P+ctlk++pn +ehti wa  
   Q: 523  DRVGPDTEHVFneeFWEDLDGVTNALDNVDARTYVDRRCVFFRKPLLESGTLGTKGNTQVVLPRITESYSSSQDPPEKTFPMCTLKSFPNRIEHTIAWArd 623
           78******99899**************************************************************************************** PP
   S: 191  ..........vlfnklleeeageeevlekldseekeegkdkvkselksedeenfeeaieiavkafakttinsikqllksfecdivtkskspfwv....... 274
                     + +n++l++ +  +++l++  + + +++++  ++ l++ ++ +f+++i +a+++f+ +++n i+qll +f+ d  t+s++ fw+       
   Q: 624  lfqtyfvgppEAVNMYLSQPNYIQQTLKQ--AGNEKQTLEHLRDFLVTDKPLTFDDCIVWARNQFEAQYNNAIQQLLYNFPRDSKTSSGQLFWSgpkrapt 722
           **********999*999988888888875..4455555566667789999*************************************************** PP
   S: 275  .................................................sfcsnaealqvpekvekdeevvkasap..............lylllralerf 312
                                                                      +p++++k +++  +++p              ++ l+ +l + 
   Q: 723  plkfdsanpthlsfivaganlhafnygiknpgadkayyrkvvdnmivpeF---------TPKSGIKIQANENDPDPdapaagssfddnqeIQRLVDSLPSP 814
           **999999999999999998888887777777776644433333333320.........34555555555555555777777778888889********** PP
   S: 313  ekkkgrkpgelsfekddds..avdlvtaaanlraeslgiepkldddlikeiagniipaiattnavvgGlaaqEviKvvsg..kfeplknfflfdae 404
           +   g   + ++fekddd   ++d++taa+nlra +++i++ +d++++k iag+iipaiatt+a v Gl+a+E++K+++g  + e++kn f+++a+
   Q: 815  KDLAGFRLNPVEFEKDDDTnhHIDFITAASNLRADNYDIPQ-ADRHKTKFIAGKIIPAIATTTALVTGLVALELFKIIDGkdDIEQYKNGFVNLAL 909
           ******************999********************.**************************************777889*****99875 PP

Organism

Aspergillus niger

Protein Sequence
(Fasta)

MTDAKMQVDN PQETVEAIKQ GEIDESLYSR QLYVLGHEAM KRMGSSNVLV VGLKGLGVEI 60
AKNIALAGVK SLTLYDPAPV AISDLSSQFF LQPQDVGKPR AEVTAPRVAE LNSYVPVTVH 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGACTGTAT GCCTTATCAC CCGGGTGATG CCAAAACAAC TTTGTCAGTT ACTGATCAGT 60
CTTAGGACGC AAAGATGCAA GTGGATAACC CACAGGAGAC TGTGGAGGCG ATCAAGCAAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0436--Ligase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR032420--E1_4HB
IPR032418--E1_FCCH
IPR016040--NAD(P)-bd_dom
IPR000594--ThiF_NAD_FAD-bd
IPR018965--Ub-activating_enz_E1_C
IPR019572--UBA_E1_Cys
IPR018075--UBQ-activ_enz_E1
IPR033127--UBQ-activ_enz_E1_Cys_AS
IPR000011--UBQ/SUMO-activ_enz_E1-like

PROSITE

PS00865--UBIQUITIN_ACTIVAT_2

Pfam

PF16191--E1_4HB
PF16190--E1_FCCH
PF09358--E1_UFD
PF00899--ThiF
PF10585--UBA_e1_thiolCys

PRINTS

PR01849--UBIQUITINACT

SMART

SM00985--UBA_e1_C

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005634--C:nucleus
GO:0005524--F:ATP binding
GO:0004839--F:ubiquitin activating enzyme activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000367	Aegilops tauschii	46.40	0.00e+00	811.00
IUUC-Aml-001311	Ailuropoda melanoleuca	53.64	0.00e+00	1093.00
IUUC-Atr-002684	Amborella trichopoda	44.16	0.00e+00	832.00
IUUC-Apl-004158	Anas platyrhynchos	42.62	0.00e+00	698.00
IUUC-Aca-004620	Anolis carolinensis	55.05	0.00e+00	1109.00
IUUC-Aly-005515	Arabidopsis lyrata	45.21	0.00e+00	853.00
IUUC-Ath-006891	Arabidopsis thaliana	44.92	0.00e+00	853.00
IUUC-Ago-007873	Ashbya gossypii	59.36	0.00e+00	1181.00
IUUC-Acl-008181	Aspergillus clavatus	88.20	0.00e+00	1863.00
IUUC-Afl-008455	Aspergillus flavus	89.94	0.00e+00	1834.00
IUUC-Afu-009065	Aspergillus fumigatus	89.50	0.00e+00	1914.00
IUUC-Ani-009371	Aspergillus nidulans	89.26	0.00e+00	1840.00
IUUC-Aor-010007	Aspergillus oryzae	90.09	0.00e+00	1826.00
IUUC-Ate-010466	Aspergillus terreus	89.90	0.00e+00	1933.00
IUUC-Ame-010933	Astyanax mexicanus	54.95	0.00e+00	1042.00
IUUC-Bgr-012281	Blumeria graminis	69.66	0.00e+00	1476.00
IUUC-Bta-012767	Bos taurus	54.12	0.00e+00	1107.00
IUUC-Bci-013721	Botrytis cinerea	72.65	0.00e+00	1476.00
IUUC-Bdi-014335	Brachypodium distachyon	46.09	0.00e+00	858.00
IUUC-Bol-015665	Brassica oleracea	45.56	0.00e+00	851.00
IUUC-Bra-017707	Brassica rapa	45.28	0.00e+00	852.00
IUUC-Cel-018260	Caenorhabditis elegans	45.59	0.00e+00	828.00
IUUC-Cja-019152	Callithrix jacchus	53.84	0.00e+00	1092.00
IUUC-Cfa-020622	Canis familiaris	52.28	0.00e+00	1040.00
IUUC-Cpo-022526	Cavia porcellus	54.52	0.00e+00	1085.00
IUUC-Cre-022702	Chlamydomonas reinhardtii	44.39	0.00e+00	783.00
IUUC-Csa-023780	Chlorocebus sabaeus	54.23	0.00e+00	1092.00
IUUC-Cho-024682	Choloepus hoffmanni	42.59	2.00e-99	355.00
IUUC-Cin-025790	Ciona intestinalis	52.83	0.00e+00	1071.00
IUUC-Csv-026084	Ciona savignyi	53.37	0.00e+00	1074.00
IUUC-Cgl-026512	Colletotrichum gloeosporioides	72.14	0.00e+00	1560.00
IUUC-Cne-026960	Cryptococcus neoformans	61.08	0.00e+00	1230.00
IUUC-Cme-027290	Cyanidioschyzon merolae	44.76	0.00e+00	842.00
IUUC-Dre-028149	Danio rerio	55.34	0.00e+00	1080.00
IUUC-Dno-028884	Dasypus novemcinctus	54.13	0.00e+00	1100.00
IUUC-Dor-030229	Dipodomys ordii	51.51	0.00e+00	1027.00
IUUC-Dse-031524	Dothistroma septosporum	73.30	0.00e+00	1547.00
IUUC-Dme-032045	Drosophila melanogaster	52.45	0.00e+00	1040.00
IUUC-Ete-033124	Echinops telfairi	42.54	2.00e-148	518.00
IUUC-Eca-033330	Equus caballus	53.94	0.00e+00	1093.00
IUUC-Eeu-035323	Erinaceus europaeus	43.24	9.00e-154	536.00
IUUC-Fca-036255	Felis catus	54.13	0.00e+00	1096.00
IUUC-Fal-036848	Ficedula albicollis	43.86	0.00e+00	707.00
IUUC-Fox-038007	Fusarium oxysporum	67.68	0.00e+00	784.00
IUUC-Fso-038339	Fusarium solani	70.97	0.00e+00	1454.00
IUUC-Gmo-039338	Gadus morhua	53.06	0.00e+00	1045.00
IUUC-Ggr-039823	Gaeumannomyces graminis	69.78	0.00e+00	1534.00
IUUC-Gga-040747	Gallus gallus	43.35	0.00e+00	702.00
IUUC-Gac-041773	Gasterosteus aculeatus	52.81	0.00e+00	1030.00
IUUC-Gma-043198	Glycine max	45.62	0.00e+00	855.00
IUUC-Ggo-045336	Gorilla gorilla	54.32	0.00e+00	1079.00
IUUC-Hsa-045982	Homo sapiens	54.32	0.00e+00	1081.00
IUUC-Hvu-047418	Hordeum vulgare	46.27	0.00e+00	841.00
IUUC-Itr-048460	Ictidomys tridecemlineatus	54.13	0.00e+00	1096.00
IUUC-Kpa-049112	Komagataella pastoris	59.75	0.00e+00	1192.00
IUUC-Lch-050371	Latimeria chalumnae	54.85	0.00e+00	1083.00
IUUC-Lpe-051299	Leersia perrieri	44.06	0.00e+00	853.00
IUUC-Loc-052936	Lepisosteus oculatus	54.76	0.00e+00	1085.00
IUUC-Lma-053315	Leptosphaeria maculans	73.77	0.00e+00	1612.00
IUUC-Laf-053948	Loxodonta africana	53.55	0.00e+00	1061.00
IUUC-Mcc-055843	Macaca mulatta	54.32	0.00e+00	1097.00
IUUC-Meu-056258	Macropus eugenii	53.55	0.00e+00	1074.00
IUUC-Mor-057269	Magnaporthe oryzae	70.10	0.00e+00	1508.00
IUUC-Mpo-057435	Magnaporthe poae	69.00	0.00e+00	1486.00
IUUC-Mtr-058572	Medicago truncatula	44.94	0.00e+00	846.00
IUUC-Mla-059176	Melampsora laricipopulina	59.41	0.00e+00	1171.00
IUUC-Mga-059721	Meleagris gallopavo	43.43	0.00e+00	679.00
IUUC-Mvi-060437	Microbotryum violaceum	56.74	0.00e+00	1151.00
IUUC-Mmr-061405	Microcebus murinus	52.96	0.00e+00	1058.00
IUUC-Mdo-062032	Monodelphis domestica	52.31	0.00e+00	1038.00
IUUC-Mmu-063280	Mus musculus	53.74	0.00e+00	1081.00
IUUC-Mac-065505	Musa acuminata	46.46	0.00e+00	859.00
IUUC-Mpu-066409	Mustela putorius furo	53.94	0.00e+00	1098.00
IUUC-Mlu-067217	Myotis lucifugus	54.13	0.00e+00	1086.00
IUUC-Nfi-068407	Neosartorya fischeri	89.70	0.00e+00	1890.00
IUUC-Ncr-068698	Neurospora crassa	70.26	0.00e+00	1484.00
IUUC-Nle-070072	Nomascus leucogenys	51.41	0.00e+00	997.00
IUUC-Opr-070715	Ochotona princeps	37.46	4.00e-174	603.00
IUUC-Ont-071671	Oreochromis niloticus	55.05	0.00e+00	1064.00
IUUC-Oan-073268	Ornithorhynchus anatinus	42.68	0.00e+00	656.00
IUUC-Ocu-074544	Oryctolagus cuniculus	54.42	0.00e+00	1105.00
IUUC-Oba-075120	Oryza barthii	45.43	0.00e+00	827.00
IUUC-Obr-076557	Oryza brachyantha	46.15	0.00e+00	818.00
IUUC-Ogl-077887	Oryza glaberrima	45.32	0.00e+00	827.00
IUUC-Ogu-078305	Oryza glumaepatula	44.11	0.00e+00	838.00
IUUC-Oin-080154	Oryza indica	44.11	0.00e+00	837.00
IUUC-Olo-081089	Oryza longistaminata	44.50	0.00e+00	845.00
IUUC-Ome-081942	Oryza meridionalis	45.32	0.00e+00	828.00
IUUC-Oni-082365	Oryza nivara	45.32	0.00e+00	827.00
IUUC-Opu-083977	Oryza punctata	45.10	0.00e+00	829.00
IUUC-Oru-084469	Oryza rufipogon	44.21	0.00e+00	840.00
IUUC-Osa-085949	Oryza sativa	45.92	0.00e+00	834.00
IUUC-Ola-087002	Oryzias latipes	54.47	0.00e+00	1074.00
IUUC-Olu-087687	Ostreococcus lucimarinus	44.82	0.00e+00	785.00
IUUC-Oga-088594	Otolemur garnettii	54.32	0.00e+00	1078.00
IUUC-Oar-090068	Ovis aries	53.89	0.00e+00	1102.00
IUUC-Ptr-090609	Pan troglodytes	42.81	0.00e+00	696.00
IUUC-Pan-092114	Papio anubis	54.23	0.00e+00	1096.00
IUUC-Psi-093489	Pelodiscus sinensis	42.72	0.00e+00	721.00
IUUC-Pma-094214	Petromyzon marinus	45.20	6.00e-36	141.00
IUUC-Pno-095154	Phaeosphaeria nodorum	73.57	0.00e+00	1615.00
IUUC-Ppa-095416	Physcomitrella patens	46.79	0.00e+00	862.00
IUUC-Pfo-097184	Poecilia formosa	54.32	0.00e+00	1060.00
IUUC-Pab-097861	Pongo abelii	54.13	0.00e+00	1064.00
IUUC-Pop-098934	Populus trichocarpa	45.68	0.00e+00	867.00
IUUC-Pca-100347	Procavia capensis	51.99	0.00e+00	909.00
IUUC-Ppe-101298	Prunus persica	45.19	0.00e+00	822.00
IUUC-Pva-102584	Pteropus vampyrus	54.13	0.00e+00	1127.00
IUUC-Pgr-103336	Puccinia graminis	56.80	0.00e+00	1086.00
IUUC-Ptt-103939	Puccinia triticina	56.02	0.00e+00	1087.00
IUUC-Pte-104200	Pyrenophora teres	74.56	0.00e+00	1640.00
IUUC-Pyt-104441	Pyrenophora triticirepentis	73.31	0.00e+00	1629.00
IUUC-Rno-105462	Rattus norvegicus	53.55	0.00e+00	1077.00
IUUC-Sce-106245	Saccharomyces cerevisiae	60.08	0.00e+00	1239.00
IUUC-Sha-107142	Sarcophilus harrisii	53.26	0.00e+00	1072.00
IUUC-Sja-107841	Schizosaccharomyces japonicus	60.73	0.00e+00	1269.00
IUUC-Spo-108034	Schizosaccharomyces pombe	61.04	0.00e+00	1256.00
IUUC-Ssl-108497	Sclerotinia sclerotiorum	72.44	0.00e+00	1494.00
IUUC-Smo-108912	Selaginella moellendorffii	46.93	0.00e+00	847.00
IUUC-Sit-110281	Setaria italica	45.21	0.00e+00	853.00
IUUC-Sly-111237	Solanum lycopersicum	46.45	0.00e+00	830.00
IUUC-Stu-112001	Solanum tuberosum	46.55	0.00e+00	831.00
IUUC-Sar-113737	Sorex araneus	53.55	0.00e+00	1090.00
IUUC-Sbi-114520	Sorghum bicolor	45.53	0.00e+00	855.00
IUUC-Sre-115148	Sporisorium reilianum	57.39	0.00e+00	1126.00
IUUC-Ssc-115777	Sus scrofa	53.89	0.00e+00	1096.00
IUUC-Tgu-116565	Taeniopygia guttata	43.76	0.00e+00	709.00
IUUC-Tru-118742	Takifugu rubripes	54.81	0.00e+00	1033.00
IUUC-Tsy-119436	Tarsius syrichta	37.68	4.00e-166	577.00
IUUC-Tni-120401	Tetraodon nigroviridis	54.66	0.00e+00	1040.00
IUUC-Tca-121672	Theobroma cacao	45.58	0.00e+00	874.00
IUUC-Tre-122009	Trichoderma reesei	69.97	0.00e+00	1430.00
IUUC-Tvi-122259	Trichoderma virens	70.57	0.00e+00	1433.00
IUUC-Tae-125676	Triticum aestivum	45.68	0.00e+00	866.00
IUUC-Tur-126189	Triticum urartu	46.50	0.00e+00	811.00
IUUC-Tme-127055	Tuber melanosporum	67.02	0.00e+00	1360.00
IUUC-Tbe-127587	Tupaia belangeri	43.55	3.00e-157	547.00
IUUC-Ttr-128331	Tursiops truncatus	53.64	0.00e+00	1083.00
IUUC-Uma-129387	Ustilago maydis	57.80	0.00e+00	1132.00
IUUC-Vda-129977	Verticillium dahliae	70.42	0.00e+00	1443.00
IUUC-Vpa-130716	Vicugna pacos	41.52	0.00e+00	682.00
IUUC-Vvi-130857	Vitis vinifera	45.41	0.00e+00	864.00
IUUC-Xtr-132026	Xenopus tropicalis	45.75	0.00e+00	796.00
IUUC-Xma-133805	Xiphophorus maculatus	53.98	0.00e+00	1045.00
IUUC-Yli-134547	Yarrowia lipolytica	59.46	0.00e+00	1247.00
IUUC-Zma-135052	Zea mays	44.97	0.00e+00	860.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence