iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Lma-053315

Ensembl Protein ID

CBX93882

UniProt Accession

E4ZRN5; E4ZRN5_LEPMJ

Genbank Protein ID

CBX93882.1

Protein Name

Similar to ubiquitin-activating enzyme E1 1

Genbank Nucleotide ID

FP929116

Gene Name

LEMA_P035560.1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
LEMA_P035560.1	CBX93882	CBX93882

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E1	7.10e-189	627.5	499	983

Active Site

Position(s)	Description	Evidence
682	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU10132}

Domain Profile

   S: 1    YDRQirlwGeeaqeklksakvllvGagglGcEllKnLvlaGv.....gsitvvDmdtvevsnlnrqFLfraedvgksKAevaaealkelnpdvnveah..e 94
           YD+Qi+++G e+qekl++ k +lvGag++GcE+lKn +l+G+     g+itv+D+d++e+snlnrqFLfr+ dvgk K+++aa+a+  +npd ++++   +
   Q: 499  YDGQIAVLGREYQEKLGNVKQFLVGAGAIGCEMLKNWALMGLgagpnGKITVTDNDQIEKSNLNRQFLFRPTDVGKLKSDAAAKAVVAMNPDLEGKIItlQ 599
           *********************************************************************************************98876226 PP
   S: 95   esiteleeeiv...FfkkfdvVvlaldnrearrkvnrlclnarvpliesgtlGllGqvrviikgltecyscsddppqktiPfctlketpnaaehtiewa.. 190
           +++ +++e+i+   F +++d+V +aldn+ear++v+r+c+  r+pl++sgtlG++G+++v+++ +te+ys+s+dpp+k++P+ctl+++pn +ehti wa  
   Q: 600  DKVGPETEHIFnetFWNELDGVTNALDNVEARTYVDRRCVFFRKPLLDSGTLGTKGNTQVVLPFITESYSSSQDPPEKSFPMCTLRSFPNRIEHTIAWAre 700
           89*******99****************************************************************************************** PP
   S: 191  ..........vlfnklleeeageeevlekldseekeegkdkvkselksedeenfeeaieiavkafakttinsikqllksfecdivtkskspfwv....... 274
                     +++n +l + +     l++  s + +++++  ++ l++e++ +f+++i +a+++f+k +++si qll +f++d  t s++pfw+       
   Q: 701  sfdslfvkgpEIVNLYLTQPDYLGASLKQ--SGNEKQTLETLRDFLVTEKPLSFDDCIIWARHQFEKNYNHSIAQLLYNFPKDSTTGSGQPFWSgpkrapd 799
           **********9999999777666666663..45555556666677999***************************************************** PP
   S: 275  ..........................sfcsnaealq.............vpekvekdeevvkasap............lylllralerfekkkgrkpgels 324
                                       ++na+++              +p+ ++k ++  k+++p            l+  ++ l + ++  g k + ++
   Q: 800  plkfdpsnqthftyveaaatlhafnyGIKPNASRAHyvevlndmivpdfQPDPTVKIQADEKEPDPnaqpsggnngdeLKDIMKQLPEPKSLAGVKLEPVE 900
           *********999999988888888884444444444555555666667777888888887777777888888888888999******************** PP
   S: 325  fekddds..avdlvtaaanlraeslgiepkldddlikeiagniipaiattnavvgGlaaqEviKvvsg..kfeplknfflfdae 404
           fekddd   ++d++taa+nlrae+++ie+ +d++++k iag+iipaiatt+a v Gl+++E++K+++g  + e++kn f+++a+
   Q: 901  FEKDDDTnhHIDFITAASNLRAENYKIEQ-ADRHKTKFIAGKIIPAIATTTALVTGLVNLELYKIIDGktDIEQYKNGFVNLAL 983
           ******999********************.**************************************777788*****99875 PP

Organism

Leptosphaeria maculans

Protein Sequence
(Fasta)

MAVSEHLIGP GPGGGETGEA AEDGSGCACA SLLAASLELG AWSLSTTRKA ILPPPSFTAL 60
HTLCCPRTAV LTHTKENMQV DSPATAVEQL KEASNNNGEI DESLYSRQLY VLGHEAMKRM 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCAGTAA GTGAGCACCT CATTGGCCCT GGACCCGGTG GTGGAGAGAC TGGAGAAGCA 60
GCAGAAGATG GCAGTGGATG CGCATGTGCA TGTGCGTGTC CTTGTCCTTG TCCCATGTGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0436--Ligase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR032420--E1_4HB
IPR032418--E1_FCCH
IPR016040--NAD(P)-bd_dom
IPR000594--ThiF_NAD_FAD-bd
IPR018965--Ub-activating_enz_E1_C
IPR019572--UBA_E1_Cys
IPR018075--UBQ-activ_enz_E1
IPR033127--UBQ-activ_enz_E1_Cys_AS
IPR000011--UBQ/SUMO-activ_enz_E1-like

PROSITE

PS00865--UBIQUITIN_ACTIVAT_2

Pfam

PF16191--E1_4HB
PF16190--E1_FCCH
PF09358--E1_UFD
PF00899--ThiF
PF10585--UBA_e1_thiolCys

PRINTS

PR01849--UBIQUITINACT

SMART

SM00985--UBA_e1_C

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005634--C:nucleus
GO:0005524--F:ATP binding
GO:0004839--F:ubiquitin activating enzyme activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000456	Aegilops tauschii	46.03	0.00e+00	859.00
IUUC-Aml-001311	Ailuropoda melanoleuca	52.36	0.00e+00	1071.00
IUUC-Atr-002684	Amborella trichopoda	44.05	0.00e+00	857.00
IUUC-Apl-004158	Anas platyrhynchos	43.19	0.00e+00	701.00
IUUC-Aca-004620	Anolis carolinensis	52.98	0.00e+00	1070.00
IUUC-Aly-005515	Arabidopsis lyrata	46.64	0.00e+00	871.00
IUUC-Ath-006891	Arabidopsis thaliana	46.36	0.00e+00	880.00
IUUC-Ago-007873	Ashbya gossypii	59.08	0.00e+00	1168.00
IUUC-Acl-008181	Aspergillus clavatus	74.25	0.00e+00	1555.00
IUUC-Afl-008455	Aspergillus flavus	73.67	0.00e+00	1506.00
IUUC-Afu-009065	Aspergillus fumigatus	74.13	0.00e+00	1581.00
IUUC-Ani-009371	Aspergillus nidulans	73.10	0.00e+00	1503.00
IUUC-Ang-009737	Aspergillus niger	73.77	0.00e+00	1555.00
IUUC-Aor-010007	Aspergillus oryzae	73.86	0.00e+00	1504.00
IUUC-Ate-010466	Aspergillus terreus	73.69	0.00e+00	1591.00
IUUC-Ame-010933	Astyanax mexicanus	54.12	0.00e+00	1016.00
IUUC-Bgr-012281	Blumeria graminis	68.79	0.00e+00	1451.00
IUUC-Bta-012767	Bos taurus	53.89	0.00e+00	1081.00
IUUC-Bci-013721	Botrytis cinerea	72.87	0.00e+00	1449.00
IUUC-Bdi-014009	Brachypodium distachyon	44.55	0.00e+00	847.00
IUUC-Bol-015665	Brassica oleracea	46.84	0.00e+00	870.00
IUUC-Bra-017685	Brassica rapa	45.64	0.00e+00	872.00
IUUC-Cel-018260	Caenorhabditis elegans	45.97	0.00e+00	828.00
IUUC-Cja-019152	Callithrix jacchus	53.25	0.00e+00	1066.00
IUUC-Cfa-020622	Canis familiaris	52.19	0.00e+00	1014.00
IUUC-Cpo-022526	Cavia porcellus	53.30	0.00e+00	1050.00
IUUC-Cre-022702	Chlamydomonas reinhardtii	43.38	0.00e+00	769.00
IUUC-Csa-023780	Chlorocebus sabaeus	52.55	0.00e+00	1070.00
IUUC-Cho-024682	Choloepus hoffmanni	41.54	1.00e-96	345.00
IUUC-Cin-025790	Ciona intestinalis	51.55	0.00e+00	1052.00
IUUC-Csv-026084	Ciona savignyi	51.18	0.00e+00	1051.00
IUUC-Cgl-026512	Colletotrichum gloeosporioides	70.41	0.00e+00	1477.00
IUUC-Cne-026960	Cryptococcus neoformans	60.02	0.00e+00	1180.00
IUUC-Cme-027290	Cyanidioschyzon merolae	42.45	0.00e+00	791.00
IUUC-Dre-028149	Danio rerio	54.62	0.00e+00	1054.00
IUUC-Dno-028884	Dasypus novemcinctus	53.20	0.00e+00	1069.00
IUUC-Dor-030229	Dipodomys ordii	49.86	0.00e+00	1008.00
IUUC-Dse-031524	Dothistroma septosporum	75.31	0.00e+00	1584.00
IUUC-Dme-032045	Drosophila melanogaster	50.84	0.00e+00	992.00
IUUC-Ete-033124	Echinops telfairi	42.58	1.00e-146	512.00
IUUC-Eca-033330	Equus caballus	53.30	0.00e+00	1066.00
IUUC-Eeu-035323	Erinaceus europaeus	42.21	1.00e-152	532.00
IUUC-Fca-036255	Felis catus	53.50	0.00e+00	1062.00
IUUC-Fal-036848	Ficedula albicollis	43.22	0.00e+00	722.00
IUUC-Fox-038007	Fusarium oxysporum	69.59	0.00e+00	783.00
IUUC-Fso-038339	Fusarium solani	70.98	0.00e+00	1431.00
IUUC-Gmo-039338	Gadus morhua	52.47	0.00e+00	1013.00
IUUC-Ggr-039823	Gaeumannomyces graminis	70.03	0.00e+00	1521.00
IUUC-Gga-040747	Gallus gallus	43.27	0.00e+00	701.00
IUUC-Gac-041773	Gasterosteus aculeatus	51.89	0.00e+00	1008.00
IUUC-Gma-043198	Glycine max	45.22	0.00e+00	859.00
IUUC-Ggo-045336	Gorilla gorilla	52.45	0.00e+00	1052.00
IUUC-Hsa-045982	Homo sapiens	52.45	0.00e+00	1051.00
IUUC-Hvu-047418	Hordeum vulgare	45.89	0.00e+00	844.00
IUUC-Itr-048460	Ictidomys tridecemlineatus	52.26	0.00e+00	1062.00
IUUC-Kpa-049112	Komagataella pastoris	59.01	0.00e+00	1186.00
IUUC-Lch-050371	Latimeria chalumnae	53.99	0.00e+00	1058.00
IUUC-Lpe-051299	Leersia perrieri	43.68	0.00e+00	843.00
IUUC-Loc-052936	Lepisosteus oculatus	52.69	0.00e+00	1059.00
IUUC-Laf-053948	Loxodonta africana	52.91	0.00e+00	1041.00
IUUC-Mcc-055843	Macaca mulatta	52.55	0.00e+00	1071.00
IUUC-Meu-056258	Macropus eugenii	52.23	0.00e+00	1041.00
IUUC-Mor-057269	Magnaporthe oryzae	70.96	0.00e+00	1504.00
IUUC-Mpo-057435	Magnaporthe poae	70.30	0.00e+00	1477.00
IUUC-Mtr-058572	Medicago truncatula	45.28	0.00e+00	856.00
IUUC-Mla-059176	Melampsora laricipopulina	58.38	0.00e+00	1126.00
IUUC-Mga-059721	Meleagris gallopavo	42.97	0.00e+00	680.00
IUUC-Mvi-060437	Microbotryum violaceum	56.39	0.00e+00	1131.00
IUUC-Mmr-061405	Microcebus murinus	51.65	0.00e+00	1033.00
IUUC-Mdo-062032	Monodelphis domestica	50.67	0.00e+00	1003.00
IUUC-Mmu-063280	Mus musculus	53.12	0.00e+00	1057.00
IUUC-Mac-065505	Musa acuminata	45.33	0.00e+00	858.00
IUUC-Mpu-066409	Mustela putorius furo	53.20	0.00e+00	1069.00
IUUC-Mlu-067217	Myotis lucifugus	53.26	0.00e+00	1058.00
IUUC-Nfi-068407	Neosartorya fischeri	74.22	0.00e+00	1564.00
IUUC-Ncr-068698	Neurospora crassa	71.77	0.00e+00	1510.00
IUUC-Nle-070072	Nomascus leucogenys	49.53	0.00e+00	962.00
IUUC-Opr-070715	Ochotona princeps	36.88	3.00e-171	593.00
IUUC-Ont-071671	Oreochromis niloticus	54.51	0.00e+00	1050.00
IUUC-Oan-073268	Ornithorhynchus anatinus	42.08	0.00e+00	646.00
IUUC-Ocu-074544	Oryctolagus cuniculus	53.43	0.00e+00	1074.00
IUUC-Oba-075120	Oryza barthii	45.76	0.00e+00	840.00
IUUC-Obr-076557	Oryza brachyantha	45.00	0.00e+00	831.00
IUUC-Ogl-077887	Oryza glaberrima	45.76	0.00e+00	842.00
IUUC-Ogu-078305	Oryza glumaepatula	44.36	0.00e+00	842.00
IUUC-Oin-080154	Oryza indica	44.26	0.00e+00	841.00
IUUC-Olo-081089	Oryza longistaminata	44.26	0.00e+00	845.00
IUUC-Ome-081942	Oryza meridionalis	45.61	0.00e+00	843.00
IUUC-Oni-082365	Oryza nivara	45.85	0.00e+00	846.00
IUUC-Opu-083977	Oryza punctata	44.94	0.00e+00	850.00
IUUC-Oru-084469	Oryza rufipogon	44.36	0.00e+00	844.00
IUUC-Osa-085949	Oryza sativa	45.66	0.00e+00	846.00
IUUC-Ola-087002	Oryzias latipes	54.41	0.00e+00	1056.00
IUUC-Olu-087687	Ostreococcus lucimarinus	42.50	0.00e+00	749.00
IUUC-Oga-088594	Otolemur garnettii	53.69	0.00e+00	1049.00
IUUC-Oar-090068	Ovis aries	53.88	0.00e+00	1077.00
IUUC-Ptr-090609	Pan troglodytes	41.79	0.00e+00	696.00
IUUC-Pan-092114	Papio anubis	52.64	0.00e+00	1073.00
IUUC-Psi-093489	Pelodiscus sinensis	43.69	0.00e+00	715.00
IUUC-Pma-094214	Petromyzon marinus	46.67	3.00e-41	159.00
IUUC-Pno-095154	Phaeosphaeria nodorum	88.79	0.00e+00	1924.00
IUUC-Ppa-095227	Physcomitrella patens	46.75	0.00e+00	869.00
IUUC-Pfo-097184	Poecilia formosa	54.56	0.00e+00	1053.00
IUUC-Pab-097861	Pongo abelii	52.26	0.00e+00	1038.00
IUUC-Pop-099577	Populus trichocarpa	44.26	0.00e+00	876.00
IUUC-Pca-100347	Procavia capensis	50.83	0.00e+00	876.00
IUUC-Ppe-102012	Prunus persica	45.01	0.00e+00	872.00
IUUC-Pva-102584	Pteropus vampyrus	52.55	0.00e+00	1097.00
IUUC-Pgr-103336	Puccinia graminis	56.60	0.00e+00	1066.00
IUUC-Ptt-103939	Puccinia triticina	55.34	0.00e+00	1064.00
IUUC-Pte-104200	Pyrenophora teres	91.09	0.00e+00	1962.00
IUUC-Pyt-104441	Pyrenophora triticirepentis	89.58	0.00e+00	1949.00
IUUC-Rno-105462	Rattus norvegicus	52.91	0.00e+00	1052.00
IUUC-Sce-106245	Saccharomyces cerevisiae	59.92	0.00e+00	1251.00
IUUC-Sha-107142	Sarcophilus harrisii	52.38	0.00e+00	1046.00
IUUC-Sja-107841	Schizosaccharomyces japonicus	59.43	0.00e+00	1239.00
IUUC-Spo-108034	Schizosaccharomyces pombe	58.51	0.00e+00	1190.00
IUUC-Ssl-108497	Sclerotinia sclerotiorum	71.88	0.00e+00	1459.00
IUUC-Smo-108912	Selaginella moellendorffii	45.49	0.00e+00	838.00
IUUC-Sit-110281	Setaria italica	45.77	0.00e+00	866.00
IUUC-Sly-110914	Solanum lycopersicum	45.61	0.00e+00	880.00
IUUC-Stu-112109	Solanum tuberosum	45.42	0.00e+00	884.00
IUUC-Sar-113737	Sorex araneus	52.87	0.00e+00	1062.00
IUUC-Sbi-114089	Sorghum bicolor	45.33	0.00e+00	871.00
IUUC-Sre-115148	Sporisorium reilianum	56.43	0.00e+00	1121.00
IUUC-Ssc-115777	Sus scrofa	53.45	0.00e+00	1068.00
IUUC-Tgu-116565	Taeniopygia guttata	43.18	0.00e+00	716.00
IUUC-Tru-118742	Takifugu rubripes	54.56	0.00e+00	1019.00
IUUC-Tsy-119436	Tarsius syrichta	37.64	1.00e-168	585.00
IUUC-Tni-120401	Tetraodon nigroviridis	54.55	0.00e+00	1023.00
IUUC-Tca-121672	Theobroma cacao	45.76	0.00e+00	880.00
IUUC-Tre-122009	Trichoderma reesei	69.83	0.00e+00	1401.00
IUUC-Tvi-122259	Trichoderma virens	70.37	0.00e+00	1407.00
IUUC-Tae-125676	Triticum aestivum	44.88	0.00e+00	857.00
IUUC-Tur-126330	Triticum urartu	45.93	0.00e+00	856.00
IUUC-Tme-127055	Tuber melanosporum	63.14	0.00e+00	1283.00
IUUC-Tbe-127587	Tupaia belangeri	42.52	5.00e-152	530.00
IUUC-Ttr-128331	Tursiops truncatus	53.26	0.00e+00	1056.00
IUUC-Uma-129387	Ustilago maydis	57.28	0.00e+00	1139.00
IUUC-Vda-129977	Verticillium dahliae	70.42	0.00e+00	1391.00
IUUC-Vpa-130716	Vicugna pacos	41.19	0.00e+00	676.00
IUUC-Vvi-130857	Vitis vinifera	45.21	0.00e+00	866.00
IUUC-Xtr-132947	Xenopus tropicalis	38.48	0.00e+00	645.00
IUUC-Xma-133805	Xiphophorus maculatus	54.46	0.00e+00	1039.00
IUUC-Yli-134547	Yarrowia lipolytica	60.00	0.00e+00	1227.00
IUUC-Zma-135052	Zea mays	44.64	0.00e+00	860.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence