iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ame-010668

Ensembl Protein ID

ENSAMXP00000018423.1

UniProt Accession

W5LF11; W5LF11_ASTMX

Genbank Protein ID

ENSAMXP00000018423

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

APWO01020078

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAMXG00000017871.1	ENSAMXT00000018423.1	ENSAMXP00000018423.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	2.30e-23	81.5	656	694
UBD/Beta-Prp	4.20e-40	138.0	523	693

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvllk 37
           gHtd+ +c++  +d t l++G+ D+t+++WDlr+g++l+
   Q: 656  GHTDGASCIDIsNDgTKLWTGGLDNTVRCWDLREGRQLQ 694
           8***********999*********************998 PP

UBD/Beta-Prp

   S: 48   lsgheaevtavkfspdgkilvtgseDrtikvwdls.....tgkcvhtlk..ghedsvlslsfspsgdklvsGshdrtirvwdletgqcl 129
           ls h + v av++s ++   v ++  + +kvwd+s     +  ++  l   + +++++s+++ p+g +l++G++ +t+ +wdl t +  
   Q: 523  LS-HGEVVCAVTISTSTR-HVYTGGKGCVKVWDISqpgskS--PMAQLDclNRDNYIRSCKLLPDGRTLIVGGEASTLSIWDLATPTPR 607
           43.444788899999985.555555589*******776432..333333559*********************************9987 PP
   S: 130  ee.tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgecv 215
            +  l+    +   ++++pd+++++s++ D+ + +Wdl +++l+r+++g htd   +++++ +g+ l +g+ld+tv+ wdl++g+ +
   Q: 608  IKaELTSSAPACYALAISPDNKVCFSCCSDGNIVVWDLHNQTLVRQFQG-HTDGASCIDISNDGTKLWTGGLDNTVRCWDLREGRQL 693
           765888888888899*********************************9.********************************99754 PP

Organism

Astyanax mexicanus

Protein Sequence
(Fasta)

TLTVLSLQAP LQPPPGSSAS AAAAAAAAAA AAASGSAQAL KLTYPETLDR IKEEFQFLQT 60
QYHSLKLECE KLATEKTEIQ RHYVMYYEMS YGLNIEMHKQ TEIAKRLNVI CAQLIPFLSQ 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ACTTTGACTG TACTTTCCTT ACAGGCACCG CTCCAACCAC CCCCTGGGTC TTCAGCCTCG 60
GCTGCAGCAG CGGCGGCGGC GGCTGCAGCA GCTGCAGCTT CTGGGAGCGC CCAGGCTCTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR005617--Groucho/TLE_N
IPR009146--Groucho_enhance
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF03920--TLE_N
PF00400--WD40

PRINTS

PR01850--GROUCHOFAMLY

SMART

SM00320--WD40

Gene Ontology

GO:0005634--C:nucleus
GO:0006355--P:regulation of transcription, DNA-templated

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Apl-003552	Anas platyrhynchos	71.78	0.00e+00	974.00
IUUC-Dre-028293	Danio rerio	95.63	0.00e+00	1203.00
IUUC-Fal-036893	Ficedula albicollis	73.56	0.00e+00	1026.00
IUUC-Gac-042241	Gasterosteus aculeatus	88.46	0.00e+00	960.00
IUUC-Loc-052056	Lepisosteus oculatus	79.21	0.00e+00	856.00
IUUC-Ont-071448	Oreochromis niloticus	95.60	0.00e+00	1009.00
IUUC-Ola-086892	Oryzias latipes	86.86	0.00e+00	1168.00
IUUC-Psi-092957	Pelodiscus sinensis	72.97	0.00e+00	792.00
IUUC-Pfo-096291	Poecilia formosa	95.41	0.00e+00	1003.00
IUUC-Tru-118532	Takifugu rubripes	93.73	0.00e+00	989.00
IUUC-Tni-119942	Tetraodon nigroviridis	88.40	0.00e+00	958.00
IUUC-Xtr-132704	Xenopus tropicalis	72.45	0.00e+00	1014.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence