iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Xtr-132329

UUCD1 version

UUC-XeT-00980

Ensembl Protein ID

ENSXETP00000046120.2

UniProt Accession

Q28EY6; Q28EY6_XENTR

Genbank Protein ID

AAI71277.1; AAI71281.1; CAJ81618.1

Protein Name

Ubiquitin-conjugating enzyme E2D 2 (UBC4/5 homolog, yeast); Ubiquitin-conjugating enzyme E2D 3; Ubiquitin-conjugating enzyme E2D 3 (UBC4/5 homolog)

Genbank Nucleotide ID

AAMC01037170; BC171281; CR762271

Gene Name

ube2d3; ube2d2; TGas005e16.1-001

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSXETG00000021323.2	ENSXETT00000046120.2	ENSXETP00000046120.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E2/UBC	6.70e-57	191.3	5	139
UBD/UBC-like/UBD_UBC	1.20e-85	284.8	5	142

Active Site

Position(s)	Description	Evidence
85	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00388}

Domain Profile

E2/UBC

   S: 1    RlkkelkelekdppegisakpvdesdltewevlilGpedtpYeggvFkleiefpedYPfkPPkvkfltkifhPnvyenGkvClsilkee 89
           R++kel++l++dpp+++sa+pv + d+++w+++i+Gp+d+pY+ggvF l+i+fp+dYPfkPPkv f+t+i+hPn+++nG++Cl+il+  
   Q: 5    RIHKELNDLARDPPAQCSAGPVGD-DMFHWQATIMGPNDSPYQGGVFFLTIHFPTDYPFKPPKVAFTTRIYHPNINSNGSICLDILR-- 90
           99**********************.9************************************************************9.. PP
   S: 90   ekWspalsvesvllsiqsllaepnpesplneeaaellkknreeykkkvr 138
           ++Wspal++++vllsi+sll++pnp++pl  e+a+++k++re+y++++r
   Q: 91   SQWSPALTISKVLLSICSLLCDPNPDDPLVPEIARIYKTDREKYNRIAR 139
           *********************************************9987 PP

UBD/UBC-like/UBD_UBC

   S: 1    rikkelkdllrdeeaqisadlvdddlfelratiagppdspyeggvffltiklptdypfkppkvafitkiyhpninsngsicldilrsqw 89
           ri+kel+dl+rd++aq+sa++v+dd+f+++ati+gp+dspy+ggvfflti++ptdypfkppkvaf+t+iyhpninsngsicldilrsqw
   Q: 5    RIHKELNDLARDPPAQCSAGPVGDDMFHWQATIMGPNDSPYQGGVFFLTIHFPTDYPFKPPKVAFTTRIYHPNINSNGSICLDILRSQW 93
           8**************************************************************************************** PP
   S: 90   saaltlskvllslcslladaepddplvaeiariyktdkekykriarewt 138
           s+alt+skvlls+csll+d++pddplv+eiariyktd+eky+riarewt
   Q: 94   SPALTISKVLLSICSLLCDPNPDDPLVPEIARIYKTDREKYNRIAREWT 142
           ************************************************8 PP

Organism

Xenopus tropicalis

Protein Sequence
(Fasta)

MALKRIHKEL NDLARDPPAQ CSAGPVGDDM FHWQATIMGP NDSPYQGGVF FLTIHFPTDY 60
PFKPPKVAFT TRIYHPNINS NGSICLDILR SQWSPALTIS KVLLSICSLL CDPNPDDPLV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CTCGCCCGAA CACCCGCCCG GCACCGGCAG CAGTAGCGAC AGAATTATGG CGCTGAAACG 60
GATCCACAAG GTGAGCTATG CCGGAGCCTT TTTTTAATCG CTGGCTCTTC ACTACCTACA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR000608--UBQ-conjugat_E2
IPR023313--UBQ-conjugating_AS
IPR016135--UBQ-conjugating_enzyme/RWD

PROSITE

PS00183--UBIQUITIN_CONJUGAT_1
PS50127--UBIQUITIN_CONJUGAT_2

Pfam

PF00179--UQ_con

Gene Ontology

GO:0005524--F:ATP binding

KEGG

xtr:548818

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001778	Ailuropoda melanoleuca	100.00	1.00e-81	294.00
IUUC-Apl-003199	Anas platyrhynchos	100.00	3.00e-81	293.00
IUUC-Aca-005236	Anolis carolinensis	100.00	4.00e-86	309.00
IUUC-Ago-007967	Ashbya gossypii	80.95	2.00e-71	260.00
IUUC-Acl-008266	Aspergillus clavatus	85.03	4.00e-74	269.00
IUUC-Afu-008956	Aspergillus fumigatus	85.71	2.00e-74	270.00
IUUC-Ani-009401	Aspergillus nidulans	83.67	6.00e-73	265.00
IUUC-Ang-009725	Aspergillus niger	84.80	4.00e-62	229.00
IUUC-Aor-010157	Aspergillus oryzae	84.35	1.00e-73	268.00
IUUC-Ate-010438	Aspergillus terreus	84.35	3.00e-73	266.00
IUUC-Ame-011831	Astyanax mexicanus	96.60	2.00e-83	300.00
IUUC-Bgr-012238	Blumeria graminis	80.27	1.00e-69	254.00
IUUC-Bta-013158	Bos taurus	100.00	4.00e-86	309.00
IUUC-Bci-013661	Botrytis cinerea	83.67	5.00e-74	269.00
IUUC-Cel-018362	Caenorhabditis elegans	93.88	1.00e-81	294.00
IUUC-Cja-019886	Callithrix jacchus	100.00	4.00e-86	309.00
IUUC-Cfa-020436	Canis familiaris	100.00	4.00e-86	309.00
IUUC-Cpo-021714	Cavia porcellus	97.96	2.00e-84	303.00
IUUC-Csa-023148	Chlorocebus sabaeus	95.27	4.00e-81	292.00
IUUC-Csv-026311	Ciona savignyi	85.62	7.00e-73	265.00
IUUC-Cgl-026490	Colletotrichum gloeosporioides	84.35	8.00e-74	268.00
IUUC-Cne-026957	Cryptococcus neoformans	80.14	2.00e-69	254.00
IUUC-Dre-027758	Danio rerio	98.64	5.00e-85	305.00
IUUC-Dno-028952	Dasypus novemcinctus	100.00	6.00e-82	295.00
IUUC-Dse-031397	Dothistroma septosporum	84.35	5.00e-74	269.00
IUUC-Dme-031594	Drosophila melanogaster	94.56	2.00e-81	293.00
IUUC-Ete-032295	Echinops telfairi	100.00	3.00e-81	293.00
IUUC-Eca-033293	Equus caballus	100.00	2.00e-81	294.00
IUUC-Eeu-034766	Erinaceus europaeus	96.43	3.00e-78	283.00
IUUC-Fca-035917	Felis catus	97.28	5.00e-84	302.00
IUUC-Fal-036904	Ficedula albicollis	97.86	2.00e-80	290.00
IUUC-Fox-038021	Fusarium oxysporum	84.35	1.00e-73	268.00
IUUC-Fso-038297	Fusarium solani	83.67	3.00e-73	266.00
IUUC-Gmo-038898	Gadus morhua	97.20	2.00e-81	293.00
IUUC-Ggr-039912	Gaeumannomyces graminis	79.61	2.00e-69	254.00
IUUC-Gga-040758	Gallus gallus	100.00	4.00e-86	309.00
IUUC-Gac-042231	Gasterosteus aculeatus	97.28	5.00e-84	302.00
IUUC-Ggo-045375	Gorilla gorilla	95.95	2.00e-82	296.00
IUUC-Hsa-045885	Homo sapiens	100.00	4.00e-86	309.00
IUUC-Itr-048882	Ictidomys tridecemlineatus	96.62	3.00e-82	296.00
IUUC-Lma-053121	Leptosphaeria maculans	84.35	3.00e-74	270.00
IUUC-Laf-053580	Loxodonta africana	100.00	8.00e-82	295.00
IUUC-Mcc-054673	Macaca mulatta	100.00	2.00e-81	294.00
IUUC-Meu-056462	Macropus eugenii	96.40	1.00e-78	284.00
IUUC-Mor-057235	Magnaporthe oryzae	83.67	4.00e-73	266.00
IUUC-Mpo-057596	Magnaporthe poae	79.61	4.00e-69	253.00
IUUC-Mla-059189	Melampsora laricipopulina	80.95	1.00e-68	251.00
IUUC-Mga-059237	Meleagris gallopavo	97.86	2.00e-80	290.00
IUUC-Mvi-060397	Microbotryum violaceum	82.31	5.00e-72	262.00
IUUC-Mmr-060889	Microcebus murinus	96.60	9.00e-84	301.00
IUUC-Mdo-062962	Monodelphis domestica	100.00	4.00e-86	309.00
IUUC-Mmu-063518	Mus musculus	100.00	4.00e-86	309.00
IUUC-Mpu-066604	Mustela putorius furo	95.89	2.00e-82	296.00
IUUC-Nfi-068599	Neosartorya fischeri	85.71	2.00e-74	270.00
IUUC-Ncr-068677	Neurospora crassa	82.99	3.00e-72	263.00
IUUC-Opr-070191	Ochotona princeps	97.84	7.00e-80	288.00
IUUC-Ont-071766	Oreochromis niloticus	98.64	4.00e-85	306.00
IUUC-Ocu-074315	Oryctolagus cuniculus	100.00	4.00e-86	309.00
IUUC-Ome-081920	Oryza meridionalis	80.95	1.00e-69	254.00
IUUC-Ola-086331	Oryzias latipes	98.64	4.00e-85	306.00
IUUC-Oga-088477	Otolemur garnettii	94.52	7.00e-82	295.00
IUUC-Oar-090038	Ovis aries	97.28	5.00e-84	302.00
IUUC-Ptr-090707	Pan troglodytes	100.00	4.00e-86	309.00
IUUC-Pan-092143	Papio anubis	100.00	4.00e-86	309.00
IUUC-Psi-094076	Pelodiscus sinensis	97.28	5.00e-84	302.00
IUUC-Pma-094405	Petromyzon marinus	94.81	1.00e-75	274.00
IUUC-Pno-094765	Phaeosphaeria nodorum	84.35	3.00e-74	270.00
IUUC-Pfo-096753	Poecilia formosa	98.64	4.00e-85	306.00
IUUC-Pab-097764	Pongo abelii	100.00	4.00e-86	309.00
IUUC-Pgr-103381	Puccinia graminis	82.31	1.00e-69	256.00
IUUC-Ptt-103723	Puccinia triticina	77.86	2.00e-61	227.00
IUUC-Pte-104015	Pyrenophora teres	84.35	4.00e-74	269.00
IUUC-Pyt-104701	Pyrenophora triticirepentis	84.35	4.00e-74	269.00
IUUC-Rno-105498	Rattus norvegicus	97.28	5.00e-84	302.00
IUUC-Sja-107729	Schizosaccharomyces japonicus	84.35	4.00e-73	266.00
IUUC-Spo-108032	Schizosaccharomyces pombe	84.35	3.00e-73	266.00
IUUC-Ssl-108443	Sclerotinia sclerotiorum	84.35	2.00e-74	270.00
IUUC-Sar-113302	Sorex araneus	100.00	3.00e-81	293.00
IUUC-Sre-115037	Sporisorium reilianum	80.56	9.00e-70	254.00
IUUC-Ssc-116154	Sus scrofa	93.88	2.00e-81	293.00
IUUC-Tgu-116727	Taeniopygia guttata	97.28	5.00e-84	302.00
IUUC-Tru-118272	Takifugu rubripes	98.64	9.00e-85	305.00
IUUC-Tni-120056	Tetraodon nigroviridis	98.64	9.00e-85	305.00
IUUC-Tre-122125	Trichoderma reesei	82.31	1.00e-71	261.00
IUUC-Tvi-122296	Trichoderma virens	82.31	1.00e-71	261.00
IUUC-Tme-126912	Tuber melanosporum	81.63	9.00e-72	261.00
IUUC-Tbe-127609	Tupaia belangeri	100.00	1.00e-67	247.00
IUUC-Uma-129648	Ustilago maydis	81.63	1.00e-71	261.00
IUUC-Vda-129695	Verticillium dahliae	84.35	8.00e-74	268.00
IUUC-Vpa-130446	Vicugna pacos	99.29	2.00e-80	291.00
IUUC-Vvi-131016	Vitis vinifera	80.27	1.00e-70	258.00
IUUC-Xma-133829	Xiphophorus maculatus	98.64	4.00e-85	306.00
IUUC-Yli-134353	Yarrowia lipolytica	78.91	6.00e-71	258.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence