iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Ggo-044522

UUCD1 version

UUC-GoG-00541

Ensembl Protein ID

ENSGGOP00000013690.2

UniProt Accession

G3RDS9; G3RDS9_GORGO

Protein Name

Uncharacterized protein

Gene Name

KDM2B

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSGGOG00000014021.2	ENSGGOT00000023704.1	ENSGGOP00000023443.1
ENSGGOG00000014021.2	ENSGGOT00000014084.2	ENSGGOP00000013690.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	1.30e-14	54.5	576	641

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/PHD

   S: 2    kvClvCgeggede.....k.....slveCekCrewfHpaClkls.....veeelpnsekwiCpkCrsk 54
           +vClvCge+g+++     +     +l+eC++C+e++Hp+Clk++     v++elpn+  w+CpkC+++
   Q: 576  AVCLVCGEAGKEDtveeeEgkfnlMLMECSICNEIIHPGCLKIKesegvVNDELPNC--WECPKCNHA 641
           79*********9977765156789*********************************..*******85 PP

Organism

Gorilla gorilla

Protein Sequence
(Fasta)

MAGPQMGGSA DDHPPRKRHA AEKQKKKTVI YTKCFEFESA TQRPIDRQRY DENEDLSDVE 60
EIVSVRGFSL EEKLRSQLYQ GDFVHAMEGK DFNYEYVQRE ALRVPLIFRE KDGLGIKMPD 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCGGGTC CGCAAATGGG GGGATCTGCA GACGATCACC CCCCACGAAA AAGACATGCA 60
GCAGAAAAGC AAAAAAAGAA AACAGTTATA TATACAAAAT GCTTTGAATT TGAGTCGGCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001810--F-box_dom
IPR032675--L_dom-like
IPR006553--Leu-rich_rpt_Cys-con_subtyp
IPR002857--Znf_CXXC
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS51058--ZF_CXXC
PS50016--ZF_PHD_2

Pfam

PF00646--F-box
PF16866--PHD_4
PF02008--zf-CXXC

SMART

SM00367--LRR_CC
SM00249--PHD

Gene Ontology

GO:0031519--C:PcG protein complex
GO:0000979--F:RNA polymerase II core promoter sequence-specific DNA binding
GO:0008270--F:zinc ion binding
GO:0048596--P:embryonic camera-type eye morphogenesis
GO:0021592--P:fourth ventricle development
GO:0035518--P:histone H2A monoubiquitination
GO:0070544--P:histone H3-K36 demethylation
GO:0021993--P:initiation of neural tube closure
GO:0021670--P:lateral ventricle development
GO:0030901--P:midbrain development
GO:0021555--P:midbrain-hindbrain boundary morphogenesis
GO:2000178--P:negative regulation of neural precursor cell proliferation
GO:0043524--P:negative regulation of neuron apoptotic process
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0030307--P:positive regulation of cell growth
GO:1902459--P:positive regulation of stem cell population maintenance
GO:0007283--P:spermatogenesis
GO:0021678--P:third ventricle development

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001358	Ailuropoda melanoleuca	95.26	0.00e+00	1721.00
IUUC-Apl-003787	Anas platyrhynchos	73.70	0.00e+00	1571.00
IUUC-Aca-004247	Anolis carolinensis	75.94	0.00e+00	1323.00
IUUC-Ame-011114	Astyanax mexicanus	69.41	1.00e-130	460.00
IUUC-Bta-013531	Bos taurus	95.63	0.00e+00	1754.00
IUUC-Cja-018876	Callithrix jacchus	97.18	0.00e+00	1759.00
IUUC-Cfa-020857	Canis familiaris	95.92	0.00e+00	1757.00
IUUC-Cpo-021967	Cavia porcellus	90.46	0.00e+00	1559.00
IUUC-Csa-023210	Chlorocebus sabaeus	99.11	0.00e+00	1737.00
IUUC-Dre-028272	Danio rerio	60.38	0.00e+00	1060.00
IUUC-Dno-030034	Dasypus novemcinctus	93.00	0.00e+00	1670.00
IUUC-Dor-030736	Dipodomys ordii	86.01	0.00e+00	994.00
IUUC-Eca-034255	Equus caballus	96.88	0.00e+00	1773.00
IUUC-Eeu-035038	Erinaceus europaeus	97.51	0.00e+00	1187.00
IUUC-Fca-035786	Felis catus	95.72	0.00e+00	1816.00
IUUC-Fal-037589	Ficedula albicollis	73.62	0.00e+00	1681.00
IUUC-Gmo-038781	Gadus morhua	63.12	3.00e-101	363.00
IUUC-Gga-041103	Gallus gallus	83.97	0.00e+00	627.00
IUUC-Gac-042378	Gasterosteus aculeatus	73.70	4.00e-159	555.00
IUUC-Hsa-045877	Homo sapiens	99.80	0.00e+00	1766.00
IUUC-Itr-049003	Ictidomys tridecemlineatus	96.59	0.00e+00	1321.00
IUUC-Lch-049950	Latimeria chalumnae	69.36	0.00e+00	1569.00
IUUC-Loc-051972	Lepisosteus oculatus	57.23	0.00e+00	767.00
IUUC-Laf-053623	Loxodonta africana	95.51	0.00e+00	1639.00
IUUC-Mcc-054943	Macaca mulatta	99.41	0.00e+00	1761.00
IUUC-Meu-056259	Macropus eugenii	84.98	0.00e+00	1570.00
IUUC-Mga-059671	Meleagris gallopavo	74.16	0.00e+00	1634.00
IUUC-Mmr-061003	Microcebus murinus	95.42	0.00e+00	1736.00
IUUC-Mdo-062017	Monodelphis domestica	80.34	0.00e+00	661.00
IUUC-Mmu-063584	Mus musculus	92.32	0.00e+00	1675.00
IUUC-Mpu-066056	Mustela putorius furo	95.73	0.00e+00	1722.00
IUUC-Mlu-067850	Myotis lucifugus	94.75	0.00e+00	1748.00
IUUC-Nle-069837	Nomascus leucogenys	95.85	0.00e+00	1618.00
IUUC-Opr-070943	Ochotona princeps	91.12	0.00e+00	1583.00
IUUC-Ont-071663	Oreochromis niloticus	57.93	0.00e+00	1288.00
IUUC-Oan-072934	Ornithorhynchus anatinus	75.57	0.00e+00	1255.00
IUUC-Ocu-074706	Oryctolagus cuniculus	95.62	0.00e+00	1744.00
IUUC-Ola-086543	Oryzias latipes	56.55	0.00e+00	1268.00
IUUC-Oga-088671	Otolemur garnettii	78.27	0.00e+00	631.00
IUUC-Oar-089560	Ovis aries	89.40	0.00e+00	1654.00
IUUC-Ptr-090875	Pan troglodytes	99.80	0.00e+00	1799.00
IUUC-Pan-091788	Papio anubis	84.63	0.00e+00	1931.00
IUUC-Psi-093382	Pelodiscus sinensis	73.98	0.00e+00	1673.00
IUUC-Pfo-096272	Poecilia formosa	56.33	0.00e+00	1219.00
IUUC-Pab-097907	Pongo abelii	93.85	0.00e+00	1610.00
IUUC-Pca-100628	Procavia capensis	88.64	0.00e+00	1420.00
IUUC-Pva-102956	Pteropus vampyrus	94.50	0.00e+00	1074.00
IUUC-Rno-105722	Rattus norvegicus	94.83	0.00e+00	1704.00
IUUC-Sha-106626	Sarcophilus harrisii	78.95	0.00e+00	1490.00
IUUC-Ssc-115918	Sus scrofa	95.04	0.00e+00	1577.00
IUUC-Tgu-117229	Taeniopygia guttata	88.08	0.00e+00	677.00
IUUC-Tru-118638	Takifugu rubripes	55.88	0.00e+00	697.00
IUUC-Tsy-118820	Tarsius syrichta	91.91	0.00e+00	768.00
IUUC-Tbe-127654	Tupaia belangeri	82.34	0.00e+00	1394.00
IUUC-Ttr-128821	Tursiops truncatus	90.27	0.00e+00	1608.00
IUUC-Xtr-131823	Xenopus tropicalis	72.67	0.00e+00	1286.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence