iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Dre-028129

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Smu-1 suppressor of mec-8 and unc-52 homolog b (C. elegans)

Genbank Nucleotide ID

CU929294

Gene Name

smu1b

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSDARG00000051970.4	ENSDART00000073694.4	ENSDARP00000068184.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.70e-28	98.3	373	412
UBD/Beta-Prp	9.00e-48	163.9	240	538

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvllks 38
           gHt+ v+++ + +d  +++s+s Dgt+kvW ++t +++++
   Q: 373  GHTAHVNDVIYsHDgQHVISASADGTVKVWTVKTMDCTHT 412
           8********999778*******************999985 PP

UBD/Beta-Prp

   S: 10   ksvitcvkfspdksllatgsrdgtikvwdvttgkllrsl.sgheae.......vtavkfspdgkilvtgseDrtikvwdlstgkcvhtl 90
           ks + c  fspd+++l+tgs dg i+vw++ttgk  + l ++ ++        v ++  s+d+ ++++g++D+ i+vw + +g+c+  l
   Q: 240  KSHVECARFSPDGQYLITGSVDGFIEVWNFTTGKICKDLkYQAQDNfmmmdeaVLCLAVSHDSHVIASGAQDGKIQVWRILNGTCLNRL 328
           77889999999999999999999999999999999888865555557888888999999999999999999999999999999999999 PP
   S: 91   k.ghedsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgg 178
           + +h++ v+s+ f++++  l+s s d+tir+  l++g+cl+  ++gh++ vn v ++ dg+ ++s+s+D+tv++W +kt+++ +t +  
   Q: 329  ErAHSKAVTSVCFNRDSTQLLSSSFDQTIRIHGLKSGKCLK-EFRGHTAHVNDVIYSHDGQHVISASADGTVKVWTVKTMDCTHTIKTP 416
           88999999999999999999999999999999999999999.99999999999999999999999999999999999999999999666 PP
   S: 179  htdsvysls......fdsngkelvsgsldgtvklwdlqtgecvrtl.nght..dnvksvrfspnderlvsgssDgsiriWdlrsgdllk 258
           + +  + ++      + ++ +++v   + +tv + ++ +g+++r++  g +  + + +  +sp++e+++++++D +++++ + +g+l +
   Q: 417  DIPEGTDITvnnvvlVPKTPEHFVVSNRTNTVVVTNI-HGQVMRSFcSGVRegADFVCCTLSPRGEWIYCVGEDYVLYCFSTITGKLER 504
           6666666664444444444499999999999999999.5555555414544554555677889************************** PP
   S: 259  tlqlhnssvisvavlsfgdnvlvlgsedskvniwk 293
           tl+ h++ vi +a+ ++ +n +++ sed+ +++wk
   Q: 505  TLTVHEKDVIGIAH-HPHQNLIATYSEDGLLKLWK 538
           **************.*******************8 PP

Organism

Danio rerio

Protein Sequence
(Fasta)

MDLEVESADV IRLIMQYLKE NNLHRTLAML QEETTVSLHT VDSIDSFISD INNGQWDIVL 60
LAIQYLKLPD KLLIDLYEQI VLELIELGEL GAAQCLLKQT DPMIMLKHTQ PERYSRMETL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AGTCGCATCC AGACGGAGGA GAGCAGAGTC GCACCAAACA CAGCCGCAGA CATGGACCTC 60
GAAGTGGAAT CCGCAGAGTA AGTCAAACAC TGGTTTTGTT TATTACATTA TTATTGTAAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR006595--CTLH_C
IPR020472--G-protein_beta_WD-40_rep
IPR006594--LisH
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS50897--CTLH
PS50896--LISH
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00668--CTLH
SM00667--LisH
SM00320--WD40

KEGG

dre:570074

Orthology

iUUCD ID