iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Eca-033385

UUCD1 version

UUC-EqC-00410

Ensembl Protein ID

ENSECAP00000019363.1

UniProt Accession

F6WSB4; F6WSB4_HORSE

Protein Name

Uncharacterized protein

Gene Name

RAG1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSECAG00000021936.1	ENSECAT00000023384.1	ENSECAP00000019363.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	93.19	0.00e+00	1961.00	IUUC-Hsa-045964
E3 activity/RING/RING	89.44	0.00e+00	1914.00	IUUC-Mmu-064297

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Equus caballus

Protein Sequence
(Fasta)

MAVSLTATLG LNSAPDEIQH PHIKFSEWKF KLFRVRSFEK APEEAQKEKD SSEGKPSLEQ 60
SPAVLDKAGG QKPVLTQPAV KPHPKFLKKS HDDGKAREKA IHQASLRHLC RICGNSFKTD 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AGAGAGCAAG GAGGGCGAGG AGAGCACACT TTGTCTTCCC TTTGGTATCA AGTCATATCA 60
ACCGAATTAC AGACATCCCC ACACTGTGCC CAGGCAGCCT GCTGAGCAAG GTAACATGCA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0233--DNA recombination
KW-0238--DNA-binding
KW-0539--Nucleus
KW-1185--Reference proteome

Interpro

IPR024627--RAG1
IPR019485--RAG1_Znf
IPR023336--RAG_nonamer-bd_dom
IPR013087--Znf_C2H2_type
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS51487--NBD
PS51765--ZF_RAG1
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF12940--RAG1
PF10426--zf-RAG1

SMART

SM00184--RING

Gene Ontology

GO:0005634--C:nucleus
GO:0004519--F:endonuclease activity
GO:0043565--F:sequence-specific DNA binding
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0002250--P:adaptive immune response
GO:0010390--P:histone monoubiquitination
GO:0043154--P:negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0070244--P:negative regulation of thymocyte apoptotic process
GO:0045582--P:positive regulation of T cell differentiation
GO:0002331--P:pre-B cell allelic exclusion
GO:0051865--P:protein autoubiquitination
GO:0033077--P:T cell differentiation in thymus
GO:0043029--P:T cell homeostasis
GO:0048538--P:thymus development
GO:0033151--P:V(D)J recombination

KEGG

ecb:100049810

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001206	Ailuropoda melanoleuca	93.29	0.00e+00	1971.00
IUUC-Apl-003271	Anas platyrhynchos	76.70	0.00e+00	1684.00
IUUC-Aca-004400	Anolis carolinensis	74.35	0.00e+00	1629.00
IUUC-Ame-011295	Astyanax mexicanus	59.08	0.00e+00	1224.00
IUUC-Bta-012421	Bos taurus	93.04	0.00e+00	1963.00
IUUC-Cja-019891	Callithrix jacchus	91.95	0.00e+00	1921.00
IUUC-Cfa-020740	Canis familiaris	84.37	0.00e+00	1825.00
IUUC-Cpo-021800	Cavia porcellus	91.93	0.00e+00	1882.00
IUUC-Csa-024203	Chlorocebus sabaeus	92.32	0.00e+00	1733.00
IUUC-Dre-028416	Danio rerio	59.23	0.00e+00	1216.00
IUUC-Dno-029101	Dasypus novemcinctus	91.28	0.00e+00	1907.00
IUUC-Fca-036545	Felis catus	92.52	0.00e+00	1960.00
IUUC-Fal-037208	Ficedula albicollis	76.21	0.00e+00	1673.00
IUUC-Gmo-039622	Gadus morhua	55.89	0.00e+00	1177.00
IUUC-Gga-041182	Gallus gallus	75.90	0.00e+00	1637.00
IUUC-Gac-041682	Gasterosteus aculeatus	58.42	0.00e+00	1205.00
IUUC-Ggo-044510	Gorilla gorilla	93.19	0.00e+00	1963.00
IUUC-Hsa-045964	Homo sapiens	93.19	0.00e+00	1961.00
IUUC-Itr-048862	Ictidomys tridecemlineatus	92.23	0.00e+00	1942.00
IUUC-Lch-050041	Latimeria chalumnae	69.93	0.00e+00	1496.00
IUUC-Loc-052464	Lepisosteus oculatus	64.15	0.00e+00	1382.00
IUUC-Laf-053544	Loxodonta africana	91.95	0.00e+00	1947.00
IUUC-Mcc-054867	Macaca mulatta	92.71	0.00e+00	1956.00
IUUC-Meu-055986	Macropus eugenii	82.05	0.00e+00	1610.00
IUUC-Mga-059262	Meleagris gallopavo	76.60	0.00e+00	1657.00
IUUC-Mdo-062686	Monodelphis domestica	82.23	0.00e+00	1810.00
IUUC-Mmu-064297	Mus musculus	89.73	0.00e+00	1951.00
IUUC-Mpu-066027	Mustela putorius furo	92.91	0.00e+00	1937.00
IUUC-Mlu-067885	Myotis lucifugus	93.58	0.00e+00	1979.00
IUUC-Nle-070073	Nomascus leucogenys	92.81	0.00e+00	1956.00
IUUC-Ont-071400	Oreochromis niloticus	61.48	0.00e+00	1269.00
IUUC-Oan-072920	Ornithorhynchus anatinus	94.42	0.00e+00	784.00
IUUC-Ocu-074616	Oryctolagus cuniculus	92.99	0.00e+00	1946.00
IUUC-Ola-086828	Oryzias latipes	60.67	0.00e+00	1251.00
IUUC-Oga-088675	Otolemur garnettii	94.83	4.00e-156	543.00
IUUC-Oar-090380	Ovis aries	92.43	0.00e+00	1965.00
IUUC-Ptr-090648	Pan troglodytes	93.29	0.00e+00	1965.00
IUUC-Pan-092036	Papio anubis	92.52	0.00e+00	1949.00
IUUC-Psi-093130	Pelodiscus sinensis	80.31	0.00e+00	1761.00
IUUC-Pfo-097273	Poecilia formosa	60.94	0.00e+00	1229.00
IUUC-Pca-100134	Procavia capensis	85.54	0.00e+00	1805.00
IUUC-Rno-105632	Rattus norvegicus	90.02	0.00e+00	1955.00
IUUC-Sha-107238	Sarcophilus harrisii	81.76	0.00e+00	1808.00
IUUC-Sar-113591	Sorex araneus	78.64	0.00e+00	1641.00
IUUC-Ssc-115720	Sus scrofa	92.33	0.00e+00	1940.00
IUUC-Tgu-117030	Taeniopygia guttata	76.69	0.00e+00	1659.00
IUUC-Tru-117669	Takifugu rubripes	56.26	0.00e+00	1144.00
IUUC-Tsy-119578	Tarsius syrichta	87.63	0.00e+00	1873.00
IUUC-Tni-120073	Tetraodon nigroviridis	57.67	0.00e+00	1192.00
IUUC-Tbe-128029	Tupaia belangeri	86.69	0.00e+00	984.00
IUUC-Ttr-128677	Tursiops truncatus	87.20	0.00e+00	807.00
IUUC-Vpa-130346	Vicugna pacos	94.80	0.00e+00	879.00
IUUC-Xtr-132442	Xenopus tropicalis	85.57	5.00e-100	356.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence