iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Aca-004680

Ensembl Protein ID

ENSACAP00000011510.3

UniProt Accession

H9GI22; H9GI22_ANOCA

Protein Name

Uncharacterized protein

Gene Name

HIC1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSACAG00000011777.3	ENSACAT00000011750.3	ENSACAP00000011510.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_Other: BTB	1.70e-13	50.7	42	101

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_Other: BTB

   S: 1    aDvilvvggeeffahkivLaasSsvFyalflmeleesksklmveikd..vqpevfrallkFlYtgkl 65
           +Dv++vv++  f+ahk vLaasS +++al  +        + v++++  v+p vfra+l+F+Ytg+l
   Q: 42   CDVVVVVQNALFRAHKNVLAASSAYLKALVVH-------DNLVNLDQemVSPPVFRAVLDFIYTGRL 101
           8*****************************66.......5789999559****************98 PP

Organism

Anolis carolinensis

Protein Sequence
(Fasta)

MLEAPSSSPP SPPPPLPPPE SPPHARQLLL QLNAQRTKGF LCDVVVVVQN ALFRAHKNVL 60
AASSAYLKAL VVHDNLVNLD QEMVSPPVFR AVLDFIYTGR LGGTDSHEGP PSEEPSLGAI 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTTGGAAG CCCCTTCCTC CTCGCCGCCC TCTCCGCCGC CGCCTCTCCC TCCGCCCGAG 60
TCCCCTCCGC ACGCCCGGCA ACTCCTGCTC CAACTCAACG CCCAGCGCAC CAAGGGCTTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR000210--BTB/POZ_dom
IPR023413--GFP-like
IPR028424--HIC1
IPR011333--SKP1/BTB/POZ
IPR013087--Znf_C2H2_type

PROSITE

PS50097--BTB
PS00028--ZINC_FINGER_C2H2_1
PS50157--ZINC_FINGER_C2H2_2

Pfam

PF00651--BTB

SMART

SM00225--BTB
SM00355--ZnF_C2H2

Gene Ontology

GO:0005829--C:cytosol
GO:0005654--C:nucleoplasm
GO:0046872--F:metal ion binding
GO:0043565--F:sequence-specific DNA binding
GO:0003700--F:transcription factor activity, sequence-specific DNA binding
GO:0008630--P:intrinsic apoptotic signaling pathway in response to DNA damage
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0030178--P:negative regulation of Wnt signaling pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001347	Ailuropoda melanoleuca	58.39	1.00e-75	277.00
IUUC-Apl-004217	Anas platyrhynchos	70.62	6.00e-76	278.00
IUUC-Ame-010967	Astyanax mexicanus	58.96	5.00e-78	285.00
IUUC-Bta-013567	Bos taurus	57.05	4.00e-76	279.00
IUUC-Cja-019621	Callithrix jacchus	87.18	4.00e-33	132.00
IUUC-Cfa-020731	Canis familiaris	56.74	8.00e-78	284.00
IUUC-Cpo-021326	Cavia porcellus	57.01	4.00e-77	282.00
IUUC-Csa-023645	Chlorocebus sabaeus	56.74	2.00e-77	283.00
IUUC-Dre-028027	Danio rerio	60.16	3.00e-81	295.00
IUUC-Dno-028900	Dasypus novemcinctus	57.05	2.00e-76	280.00
IUUC-Dor-030484	Dipodomys ordii	62.90	1.00e-42	166.00
IUUC-Ete-033019	Echinops telfairi	53.66	8.00e-37	148.00
IUUC-Eca-033737	Equus caballus	67.96	7.00e-73	268.00
IUUC-Eeu-035190	Erinaceus europaeus	55.70	1.00e-43	170.00
IUUC-Fca-036031	Felis catus	67.96	6.00e-73	268.00
IUUC-Fal-036980	Ficedula albicollis	52.42	2.00e-88	320.00
IUUC-Gmo-039209	Gadus morhua	69.02	1.00e-73	270.00
IUUC-Gga-040708	Gallus gallus	51.34	7.00e-147	514.00
IUUC-Gac-041742	Gasterosteus aculeatus	78.57	2.00e-78	286.00
IUUC-Ggo-044591	Gorilla gorilla	57.05	3.00e-77	282.00
IUUC-Hsa-046769	Homo sapiens	57.05	4.00e-77	282.00
IUUC-Itr-048627	Ictidomys tridecemlineatus	56.74	4.00e-77	282.00
IUUC-Lch-049412	Latimeria chalumnae	58.96	4.00e-85	308.00
IUUC-Loc-052129	Lepisosteus oculatus	70.95	8.00e-76	277.00
IUUC-Laf-053358	Loxodonta africana	56.43	1.00e-77	284.00
IUUC-Mcc-054981	Macaca mulatta	56.74	2.00e-77	283.00
IUUC-Meu-056181	Macropus eugenii	61.88	3.00e-56	212.00
IUUC-Mga-059592	Meleagris gallopavo	64.49	5.00e-86	311.00
IUUC-Mmr-061560	Microcebus murinus	56.11	2.00e-77	283.00
IUUC-Mdo-062271	Monodelphis domestica	67.60	5.00e-72	265.00
IUUC-Mmu-064258	Mus musculus	57.05	1.00e-77	284.00
IUUC-Mpu-065911	Mustela putorius furo	56.74	1.00e-77	283.00
IUUC-Mlu-067575	Myotis lucifugus	63.08	6.00e-80	291.00
IUUC-Nle-069726	Nomascus leucogenys	67.27	1.00e-65	243.00
IUUC-Opr-071056	Ochotona princeps	55.70	2.00e-44	173.00
IUUC-Ont-072493	Oreochromis niloticus	55.95	3.00e-75	276.00
IUUC-Ocu-073887	Oryctolagus cuniculus	67.96	9.00e-73	268.00
IUUC-Ola-086584	Oryzias latipes	63.47	8.00e-79	288.00
IUUC-Oga-088774	Otolemur garnettii	57.05	1.00e-76	281.00
IUUC-Ptr-090491	Pan troglodytes	57.55	1.00e-69	256.00
IUUC-Pan-092901	Papio anubis	69.10	5.00e-73	268.00
IUUC-Psi-093684	Pelodiscus sinensis	70.62	1.00e-75	277.00
IUUC-Pma-094179	Petromyzon marinus	73.97	2.00e-29	119.00
IUUC-Pfo-096282	Poecilia formosa	56.35	1.00e-75	277.00
IUUC-Pab-098488	Pongo abelii	57.05	3.00e-77	282.00
IUUC-Pca-100667	Procavia capensis	56.15	2.00e-77	283.00
IUUC-Pva-102421	Pteropus vampyrus	56.74	9.00e-78	284.00
IUUC-Rno-105528	Rattus norvegicus	55.80	1.00e-74	274.00
IUUC-Sar-113478	Sorex araneus	56.45	4.00e-69	255.00
IUUC-Ssc-115420	Sus scrofa	55.94	7.00e-78	285.00
IUUC-Tgu-116642	Taeniopygia guttata	52.15	4.00e-86	311.00
IUUC-Tru-118583	Takifugu rubripes	72.35	1.00e-72	267.00
IUUC-Tni-119907	Tetraodon nigroviridis	61.54	1.00e-63	236.00
IUUC-Xtr-132210	Xenopus tropicalis	51.00	2.00e-153	535.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence