iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Oar-089243

Ensembl Protein ID

ENSOARP00000011221.1

UniProt Accession

W5PL98; W5PL98_SHEEP

Genbank Protein ID

ENSOARP00000011221

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AMGL01098073

Gene Name

KLHL5

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOARG00000010455.1	ENSOART00000011381.1	ENSOARP00000011221.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB	2.80e-19	69.4	220	287
E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box	1.60e-08	33.8	319	348

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB

   S: 1    aDvilvvggeeffahkivLaasSsvFyalflmeleesksklmveikdvqpevfrallkFlYtgkldene 69
           +Dvilv g+++++ah++vL++ S++F a+f+++ +e + ++++++++v+p ++  l+++ Ytg+l+++e
   Q: 220  CDVILVAGDRRIPAHRLVLSSVSDYFAAMFTSDVREAR-QEEIKMEGVEPNSLWSLIQYAYTGRLELKE 287
           9************************************9.**************************9986 PP

E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box

   S: 1    leNclgilrfAdlydcpdLkdaaldfilkh 30
           ++Nclgi++fAd+ +c+dL+++a++++  +
   Q: 319  PSNCLGIRSFADAQGCTDLHKVAHNYTMEN 348
           89************************8555 PP

Organism

Ovis aries

Protein Sequence
(Fasta)

VNVIYFPFNL FIVYSRAYTS LILVGCTNLC AVLFARCLDD HLVSLRMSGS RKEFDVKQIL 60
KIRWRWFSHQ ASSPNSTVDS QQGEFWNRGQ TGANGGRKFL DPCSLQLPLA SIGYRRSSQL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTGAATGTGA TTTATTTTCC TTTCAATTTG TTTATTGTGT ACAGCAGGGC ATATACTTCT 60
CTTATCTTGG TTGGATGCAC AAATCTGTGT GCAGTGCTTT TTGCCCGTTG CCTAGACGAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0880--Kelch repeat
KW-0472--Membrane
KW-1185--Reference proteome
KW-0677--Repeat
KW-0812--Transmembrane
KW-1133--Transmembrane helix

Interpro

IPR011705--BACK
IPR000210--BTB/POZ_dom
IPR015915--Kelch-typ_b-propeller
IPR006652--Kelch_1
IPR011333--SKP1/BTB/POZ

PROSITE

PS50097--BTB

Pfam

PF07707--BACK
PF00651--BTB
PF01344--Kelch_1

SMART

SM00875--BACK
SM00225--BTB
SM00612--Kelch

Gene Ontology

GO:0016021--C:integral component of membrane

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000220	Aegilops tauschii	32.92	2.00e-39	157.00
IUUC-Aml-001239	Ailuropoda melanoleuca	99.65	0.00e+00	1191.00
IUUC-Apl-003930	Anas platyrhynchos	89.26	0.00e+00	1217.00
IUUC-Aca-004826	Anolis carolinensis	88.05	0.00e+00	1337.00
IUUC-Ame-011037	Astyanax mexicanus	80.81	0.00e+00	838.00
IUUC-Bta-013448	Bos taurus	99.47	0.00e+00	1506.00
IUUC-Bdi-014143	Brachypodium distachyon	35.29	6.00e-43	169.00
IUUC-Cja-019953	Callithrix jacchus	98.15	0.00e+00	1493.00
IUUC-Cfa-020335	Canis familiaris	99.32	0.00e+00	1477.00
IUUC-Cpo-021385	Cavia porcellus	98.78	0.00e+00	1466.00
IUUC-Csa-023109	Chlorocebus sabaeus	99.01	0.00e+00	1415.00
IUUC-Cho-024402	Choloepus hoffmanni	98.58	0.00e+00	1393.00
IUUC-Csv-026377	Ciona savignyi	65.54	0.00e+00	765.00
IUUC-Dre-028618	Danio rerio	83.27	0.00e+00	998.00
IUUC-Dme-032222	Drosophila melanogaster	58.21	0.00e+00	675.00
IUUC-Eca-034002	Equus caballus	99.32	0.00e+00	1472.00
IUUC-Fca-035953	Felis catus	91.90	0.00e+00	1375.00
IUUC-Fal-037331	Ficedula albicollis	93.46	0.00e+00	1192.00
IUUC-Gmo-039309	Gadus morhua	76.98	0.00e+00	912.00
IUUC-Gga-041137	Gallus gallus	96.83	0.00e+00	1167.00
IUUC-Gac-042162	Gasterosteus aculeatus	78.38	0.00e+00	896.00
IUUC-Ggo-044697	Gorilla gorilla	98.37	0.00e+00	1472.00
IUUC-Hsa-047037	Homo sapiens	97.71	0.00e+00	1469.00
IUUC-Hvu-047224	Hordeum vulgare	31.93	9.00e-39	155.00
IUUC-Lch-050568	Latimeria chalumnae	85.70	0.00e+00	1298.00
IUUC-Lpe-051276	Leersia perrieri	27.81	9.00e-41	162.00
IUUC-Loc-052139	Lepisosteus oculatus	78.87	0.00e+00	1155.00
IUUC-Laf-054213	Loxodonta africana	98.87	0.00e+00	1416.00
IUUC-Mcc-054988	Macaca mulatta	98.67	0.00e+00	1506.00
IUUC-Mga-059394	Meleagris gallopavo	84.99	0.00e+00	1287.00
IUUC-Mmr-061186	Microcebus murinus	99.22	0.00e+00	1061.00
IUUC-Mdo-062687	Monodelphis domestica	97.18	0.00e+00	1386.00
IUUC-Mmu-063695	Mus musculus	97.04	0.00e+00	1387.00
IUUC-Mpu-065886	Mustela putorius furo	91.91	0.00e+00	1383.00
IUUC-Mlu-067820	Myotis lucifugus	98.28	0.00e+00	1499.00
IUUC-Nle-069647	Nomascus leucogenys	98.41	0.00e+00	1505.00
IUUC-Opr-070814	Ochotona princeps	97.42	0.00e+00	1444.00
IUUC-Ont-071631	Oreochromis niloticus	77.93	0.00e+00	900.00
IUUC-Oan-073455	Ornithorhynchus anatinus	94.25	0.00e+00	1182.00
IUUC-Ogl-077595	Oryza glaberrima	33.73	7.00e-37	149.00
IUUC-Olo-080536	Oryza longistaminata	34.52	2.00e-38	154.00
IUUC-Osa-085891	Oryza sativa	33.73	6.00e-38	152.00
IUUC-Oga-088236	Otolemur garnettii	97.88	0.00e+00	1493.00
IUUC-Ptr-090722	Pan troglodytes	98.15	0.00e+00	1502.00
IUUC-Pan-092727	Papio anubis	98.73	0.00e+00	1412.00
IUUC-Psi-093068	Pelodiscus sinensis	91.23	0.00e+00	1333.00
IUUC-Pma-094371	Petromyzon marinus	80.50	0.00e+00	985.00
IUUC-Ppa-095209	Physcomitrella patens	30.04	1.00e-20	94.00
IUUC-Pfo-096355	Poecilia formosa	78.42	0.00e+00	901.00
IUUC-Pab-097795	Pongo abelii	99.42	0.00e+00	1081.00
IUUC-Pop-099153	Populus trichocarpa	31.12	4.00e-35	142.00
IUUC-Pva-103111	Pteropus vampyrus	98.24	0.00e+00	1457.00
IUUC-Rno-105085	Rattus norvegicus	97.46	0.00e+00	1390.00
IUUC-Sha-107240	Sarcophilus harrisii	96.47	0.00e+00	1375.00
IUUC-Sit-109883	Setaria italica	24.33	4.00e-16	80.10
IUUC-Sar-113739	Sorex araneus	96.88	0.00e+00	1179.00
IUUC-Sbi-114612	Sorghum bicolor	29.66	1.00e-33	138.00
IUUC-Ssc-115542	Sus scrofa	98.97	0.00e+00	949.00
IUUC-Tgu-116703	Taeniopygia guttata	92.05	0.00e+00	1343.00
IUUC-Tru-117551	Takifugu rubripes	66.62	0.00e+00	899.00
IUUC-Tsy-118944	Tarsius syrichta	92.02	0.00e+00	1363.00
IUUC-Tni-120665	Tetraodon nigroviridis	77.48	0.00e+00	875.00
IUUC-Tvi-122551	Trichoderma virens	32.26	2.00e-06	45.40
IUUC-Tae-124075	Triticum aestivum	33.20	9.00e-40	158.00
IUUC-Tur-126089	Triticum urartu	32.49	5.00e-39	156.00
IUUC-Ttr-128501	Tursiops truncatus	98.51	0.00e+00	1468.00
IUUC-Vpa-130295	Vicugna pacos	90.51	0.00e+00	1320.00
IUUC-Xtr-132607	Xenopus tropicalis	82.68	0.00e+00	1211.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence