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Tag Content
UUCD2 ID IUUC-Cfa-020932
UUCD1 version UUC-CaF-00579
Ensembl Protein ID ENSCAFP00000042948.1
UniProt Accession J9PAX0; J9PAX0_CANLF
Genbank Protein ID ENSCAFP00000042948
Protein Name Uncharacterized protein
Genbank Nucleotide ID AAEX03003515
Gene Name CUL5
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSCAFG00000014613.4 ENSCAFT00000043293.2 ENSCAFP00000042948.1
ENSCAFG00000014613.4 ENSCAFT00000023239.2 ENSCAFP00000021581.2
Status Unreviewed
Classification
Family E-Value Score Start End
E3 adaptor/Cullin RING/Cullin 2.90e-230 766.4 1 651
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 adaptor/Cullin RING/Cullin
   S: 2    lreavkkilrqesv.kkeyeelytavynlclsk..vgaklYkklkevleefikqvkkkveesedeq.lLktynreWekfreqlkvlrki 86
           +r +v k+lrqesv k+++ +l+++v+++cl++  + ak++++lke++ efikq++++v +++d++ lLk+y++eW+kf++q+++l+k+
   Q: 1    MRPIVLKLLRQESVtKQQWFDLFSDVHAVCLWDdkGPAKIHQALKEDILEFIKQAQARVLSHQDDTaLLKAYIVEWRKFFTQCDILPKP 89
           5789****************************9999***************************************************** PP
   S: 87   fayldrtyvkk....skkv.....sevrkLaldlwrkeivedikkrllelllklieaeRkgeavdrrllsgvveslveLslnk...lai 163
           f++l+ t ++k    +  +     s vrkL+ld+w+++i+++ik+rl+++++kl++aeR gea+d++l+ gv+es+v+L++n    l+i
   Q: 90   FCQLEITLMGKqgsnK--KstvedSIVRKLMLDTWNESIFSNIKNRLQDSAMKLVHAERLGEAFDSQLVIGVRESYVNLCSNPedkLQI 176
           ***********77541..24568899*******************************************************99999*** PP
   S: 164  ykesFEakfleatqefykaesaeflqenevdeYlkkvearlneeeeraaryleestetk....Llevvekeliakhlesllaelvallr 248
           y+++FE+++l++t++fy++++ ++lq+n+v++Y+k+++a+l+eee+ra ryle+++e++    L+e+++++l++++ e++lae++ +++
   Q: 177  YRDNFEKAYLDSTERFYRTQAPSYLQQNGVQNYMKYADAKLKEEEKRALRYLETRRECNsveaLMECCVNALVTSFKETILAECQGMIK 265
           *********************************************************999999************************** PP
   S: 249  dkktedlsrmykLlsrvlngleellkeleshikeqgkaalt..aeekekdpkkyVerllelknklqklvseaFnndakFlkaldkafet 335
           +++te+l++m++L+++v+ng+e++lk+le+hi ++g+a+++  ae++++d++kyVe+ll+l+n+++klv+eaF++d++Fl+a+dka+++
   Q: 266  RNETEKLHLMFSLMDKVPNGIEPMLKDLEEHIISAGLADMVaaAETITTDSEKYVEQLLTLFNRFSKLVKEAFQDDPRFLTARDKAYKA 354
           ****************************************99999******************************************** PP
   S: 336  fvnknsvlka................akspEllAryiDqlLrks..skglteeeleaqldkvllvfkyisekdvFekyYkkhLakRLls 406
           +vn+++++k+                +k+pEllA+y+D+lLrk+  sk+lt+ee+ea+l++vllv+ky+++kdvF++y+k hL++RL++
   Q: 355  VVNDATIFKLelplkqkgvglktqpeSKCPELLANYCDMLLRKTplSKKLTSEEIEAKLKEVLLVLKYVQNKDVFMRYHKAHLTRRLIL 443
           ***************************************************************************************** PP
   S: 407  gksasseaEesviekLkeec.gaeftskLerMfqdlkvSedlnrqFk.eekenteesesvelsvlvLsagaWptasetekvsLPaelek 493
           ++sa+se+Ee+++e+L+e++ +a++++kL+rMfqd+kvSedln++Fk ++k+n+ + +++++++++L+agaW+++se++ vsLP+ele+
   Q: 444  DISADSEIEENMVEWLREVGmPADYVNKLARMFQDIKVSEDLNQAFKeMHKNNKLALPADSVNIKILNAGAWSRSSEKVFVSLPTELED 532
           ***********************************************5688888899******************************** PP
   S: 494  tiekfeefYlekhsgRkLqWqhtlgraelkaelkkgkyelqVstfQmavLLafnns..ekvsveelkkatelpeeeLrrtlqsLvs.sk 579
           +i+++eefY+++hsgRkL+W+h ++++ +++++++g+y+l+V+tfQ+avL+a+n++  ek+s+e+lk atelp++eLrrtl+sLv+ +k
   Q: 533  LIPEVEEFYKKNHSGRKLHWHHLMSNGIITFKNEVGQYDLEVTTFQLAVLFAWNQRprEKISFENLKLATELPDAELRRTLWSLVAfPK 621
           *******************************************************999****************************999 PP
   S: 580  ..kqvlkkepeske...ieeedlfsvNqef 604
             +qvl +ep+ ++   ++e++lfsvNqef
   Q: 622  lkRQVLLYEPQVNSpkdFTEGTLFSVNQEF 651
           999********977778************9 PP
   
Organism Canis familiaris
Protein Sequence
(Fasta)
MRPIVLKLLR QESVTKQQWF DLFSDVHAVC LWDDKGPAKI HQALKEDILE FIKQAQARVL 60
SHQDDTALLK AYIVEWRKFF TQCDILPKPF CQLEITLMGK QGSNKKSTVE DSIVRKLMLD 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Cfa-020932|E3,Cullin|Canis familiaris
Please wait for a moment...
Nucleotide Sequence
(Fasta)
ATTAAGTGTA ATTATGCCAA TAGCCAATGA CTACATTTTC CCCCCATCCA AAGAGTTTTA 60
TTTTATGTGT TATAATCTGT TACTGTCATT TATTTTGCTT AGATTAAATA CTTTCTTACT 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Cfa-020932|E3,Cullin|Canis familiaris
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
Interpro

IPR016157--Cullin_CS
IPR016158--Cullin_homology
IPR001373--Cullin_N
IPR019559--Cullin_neddylation_domain
IPR016159--Cullin_repeat-like_dom
IPR011991--WHTH_DNA-bd_dom
PROSITE

PS01256--CULLIN_1
PS50069--CULLIN_2
Pfam

PF00888--Cullin
PF10557--Cullin_Nedd8
SMART

SM00182--CULLIN
SM00884--Cullin_Nedd8
Gene Ontology

GO:0080008--C:Cul4-RING E3 ubiquitin ligase complex
GO:0031466--C:Cul5-RING ubiquitin ligase complex
GO:0031625--F:ubiquitin protein ligase binding
GO:0006974--P:cellular response to DNA damage stimulus
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process
KEGG cfa:489422
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-002082 Ailuropoda melanoleuca 99.60 0.00e+00 1521.00
IUUC-Apl-003564 Anas platyrhynchos 99.47 0.00e+00 1523.00
IUUC-Aca-004319 Anolis carolinensis 99.21 0.00e+00 1519.00
IUUC-Ame-011742 Astyanax mexicanus 96.97 0.00e+00 1489.00
IUUC-Bta-012515 Bos taurus 99.87 0.00e+00 1527.00
IUUC-Cel-018522 Caenorhabditis elegans 52.02 0.00e+00 750.00
IUUC-Cja-018785 Callithrix jacchus 99.74 0.00e+00 1525.00
IUUC-Cpo-022317 Cavia porcellus 99.60 0.00e+00 1524.00
IUUC-Csa-023949 Chlorocebus sabaeus 99.87 0.00e+00 1527.00
IUUC-Cho-024570 Choloepus hoffmanni 99.07 3.00e-127 448.00
IUUC-Cin-025540 Ciona intestinalis 73.02 7.00e-152 530.00
IUUC-Csv-025978 Ciona savignyi 65.26 0.00e+00 999.00
IUUC-Dre-027958 Danio rerio 96.84 0.00e+00 1502.00
IUUC-Dno-029195 Dasypus novemcinctus 99.87 0.00e+00 1526.00
IUUC-Dor-030573 Dipodomys ordii 87.25 1.00e-173 603.00
IUUC-Dme-032083 Drosophila melanogaster 68.13 0.00e+00 922.00
IUUC-Ete-032428 Echinops telfairi 82.21 0.00e+00 1193.00
IUUC-Eca-033232 Equus caballus 99.74 0.00e+00 1524.00
IUUC-Eeu-035348 Erinaceus europaeus 100.00 0.00e+00 757.00
IUUC-Fca-035401 Felis catus 99.47 0.00e+00 1504.00
IUUC-Fal-037514 Ficedula albicollis 99.47 0.00e+00 1522.00
IUUC-Gmo-038577 Gadus morhua 94.09 0.00e+00 1453.00
IUUC-Gga-041096 Gallus gallus 99.47 0.00e+00 1521.00
IUUC-Gac-042108 Gasterosteus aculeatus 95.01 0.00e+00 1466.00
IUUC-Ggo-045313 Gorilla gorilla 99.87 0.00e+00 1526.00
IUUC-Hsa-045974 Homo sapiens 99.87 0.00e+00 1527.00
IUUC-Itr-049009 Ictidomys tridecemlineatus 99.87 0.00e+00 1524.00
IUUC-Lch-050615 Latimeria chalumnae 98.95 0.00e+00 1514.00
IUUC-Loc-051807 Lepisosteus oculatus 98.29 0.00e+00 1506.00
IUUC-Laf-053601 Loxodonta africana 99.87 0.00e+00 1525.00
IUUC-Mcc-055260 Macaca mulatta 99.87 0.00e+00 1526.00
IUUC-Meu-056632 Macropus eugenii 99.35 0.00e+00 912.00
IUUC-Mga-059658 Meleagris gallopavo 99.34 0.00e+00 1519.00
IUUC-Mmr-061424 Microcebus murinus 89.72 0.00e+00 1326.00
IUUC-Mdo-061836 Monodelphis domestica 99.47 0.00e+00 1520.00
IUUC-Mmu-063757 Mus musculus 98.29 0.00e+00 1506.00
IUUC-Mpu-065823 Mustela putorius furo 99.87 0.00e+00 1528.00
IUUC-Mlu-066969 Myotis lucifugus 99.47 0.00e+00 1520.00
IUUC-Nle-069943 Nomascus leucogenys 99.87 0.00e+00 1527.00
IUUC-Opr-070820 Ochotona princeps 99.77 0.00e+00 866.00
IUUC-Ont-072527 Oreochromis niloticus 95.92 0.00e+00 1485.00
IUUC-Oan-072743 Ornithorhynchus anatinus 99.47 0.00e+00 1524.00
IUUC-Ocu-074586 Oryctolagus cuniculus 99.87 0.00e+00 1527.00
IUUC-Ola-087526 Oryzias latipes 95.92 0.00e+00 1484.00
IUUC-Oga-088425 Otolemur garnettii 95.39 0.00e+00 1486.00
IUUC-Oar-089785 Ovis aries 99.87 0.00e+00 1527.00
IUUC-Ptr-091242 Pan troglodytes 99.87 0.00e+00 1527.00
IUUC-Pan-092246 Papio anubis 99.87 0.00e+00 1527.00
IUUC-Psi-094081 Pelodiscus sinensis 99.47 0.00e+00 1523.00
IUUC-Pma-094735 Petromyzon marinus 81.90 0.00e+00 721.00
IUUC-Pfo-096357 Poecilia formosa 95.65 0.00e+00 1481.00
IUUC-Pab-098248 Pongo abelii 93.54 0.00e+00 1405.00
IUUC-Pca-100756 Procavia capensis 88.27 0.00e+00 876.00
IUUC-Pva-102990 Pteropus vampyrus 85.13 0.00e+00 872.00
IUUC-Rno-105887 Rattus norvegicus 98.55 0.00e+00 1509.00
IUUC-Sha-107016 Sarcophilus harrisii 99.47 0.00e+00 1520.00
IUUC-Sar-113558 Sorex araneus 93.94 0.00e+00 1455.00
IUUC-Ssc-115414 Sus scrofa 99.87 0.00e+00 1527.00
IUUC-Tgu-116801 Taeniopygia guttata 98.95 0.00e+00 1509.00
IUUC-Tru-117565 Takifugu rubripes 96.31 0.00e+00 1488.00
IUUC-Tsy-119292 Tarsius syrichta 93.88 0.00e+00 1374.00
IUUC-Tni-120471 Tetraodon nigroviridis 96.18 0.00e+00 1483.00
IUUC-Tbe-127838 Tupaia belangeri 93.94 0.00e+00 1457.00
IUUC-Ttr-128345 Tursiops truncatus 99.47 0.00e+00 1520.00
IUUC-Vpa-130191 Vicugna pacos 90.22 0.00e+00 808.00
IUUC-Xtr-132810 Xenopus tropicalis 98.68 0.00e+00 1512.00
Created Date 25-Jun-2017

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