iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSRNOG00000014869.7	ENSRNOT00000082642.1	ENSRNOP00000074822.1
ENSRNOG00000014869.7	ENSRNOT00000048904.1	ENSRNOP00000045516.1

Annotation

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress
DNA & RNA Element
microRNA	TRANSFAC	RAID2
Protein-protein Interaction
IID
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.50e-27	94.8	144	181
UBD/Beta-Prp	3.60e-41	141.7	65	324

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvll 36
           gH+  vt+la  +d   l++Gs+D+++ +WD+ tg ++
   Q: 144  GHAMVVTGLAVsPDsSQLCTGSRDNSLLLWDVGTGQCV 181
           78889*******99999*****************9997 PP

UBD/Beta-Prp

   S: 13   itcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdls.tgkcvhtlkghedsvlsl 100
           +++v+   +++l+++g++d+t  v++++tg ++r++ ghe e+t + ++p+++ + ++s+D+t+  wdl+ ++++ + l+gh   v+ l
   Q: 65   VSVVAA-LNSDLCISGGKDKTAVVYNWKTGHVVRRFIGHEREITKIACIPKSNQFFSASRDKTVLMWDLQgSSQPRQQLSGHAMVVTGL 152
           443333.6899***********************************************************66778899*********** PP
   S: 101  sfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsvyslsfd 189
           ++sp+++ l +Gs+d+ + +wd+ tgqc+e   s+ + +v+++++ p + ++v  s D+t+rlWd +  ++ + +   +++  ++ +++
   Q: 153  AVSPDSSQLCTGSRDNSLLLWDVGTGQCVE-RASVSRNLVTHLCWVPREPYIVQTSEDKTIRLWDCRGLQMAHVFPT-KQHIQTHCEVS 239
           ******************************.********************************************54.34444556666 PP
   S: 190  sngkelvsgsl.....dgtvklwdlq.tgecvrtlnghtdnvksvrfspnd....erlvsgssDgsiriWdlrsgdllktlqlhn 264
            +g  +vs+s          +lwdl+ t e + +++gh ++v s  f+p++      +++ ++D  ++iW+ ++g +l+tl+l  
   Q: 240  VDGHTCVSCSSgfggeGCEATLWDLRqTRERMCEYKGHFQTVASCVFLPKSaalmPMIATSAHDSKVKIWNQDTGACLSTLSLDG 324
           6678999998622222579******999999*****************88722224678888*******************9976 PP

Organism

Rattus norvegicus

Protein Sequence
(Fasta)

MLALDCQLKP ALPQKVFCRL WASMGKLQSK LRYSTYLYSR PDGIIEERVQ TKASQEYIPA 60
HVDTVSVVAA LNSDLCISGG KDKTAVVYNW KTGHVVRRFI GHEREITKIA CIPKSNQFFS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CCTGTGGAAG CTACGGATGC CAGCTACCCG TGCTTGCGGG CCTCAGTGCC AGCCCGCCGG 60
TGGGTATGGA GCCCGAGGTG GGAGAGGGGA GCATCGGAGA GGTGGGAGTC CTTGCGCTGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

KEGG

rno:298096

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001303	Ailuropoda melanoleuca	78.75	5.00e-165	573.00
IUUC-Apl-003536	Anas platyrhynchos	60.56	3.00e-130	457.00
IUUC-Ame-010794	Astyanax mexicanus	52.17	6.00e-93	333.00
IUUC-Bta-013442	Bos taurus	82.29	0.00e+00	634.00
IUUC-Cel-018695	Caenorhabditis elegans	34.51	8.00e-35	140.00
IUUC-Cja-019562	Callithrix jacchus	81.47	0.00e+00	635.00
IUUC-Cfa-021028	Canis familiaris	81.22	9.00e-100	355.00
IUUC-Cpo-022343	Cavia porcellus	81.74	7.00e-172	596.00
IUUC-Csa-023542	Chlorocebus sabaeus	83.92	0.00e+00	647.00
IUUC-Cho-024760	Choloepus hoffmanni	62.15	1.00e-57	216.00
IUUC-Dre-027522	Danio rerio	55.23	1.00e-111	396.00
IUUC-Dno-029896	Dasypus novemcinctus	84.58	1.00e-118	418.00
IUUC-Dor-030765	Dipodomys ordii	74.93	4.00e-165	573.00
IUUC-Ete-033063	Echinops telfairi	67.21	1.00e-131	462.00
IUUC-Eca-033609	Equus caballus	82.02	6.00e-176	609.00
IUUC-Eeu-034966	Erinaceus europaeus	80.39	2.00e-176	611.00
IUUC-Fca-036069	Felis catus	83.10	3.00e-180	624.00
IUUC-Fal-036667	Ficedula albicollis	61.05	6.00e-123	433.00
IUUC-Gmo-039012	Gadus morhua	50.57	4.00e-103	367.00
IUUC-Gga-040523	Gallus gallus	61.05	9.00e-124	436.00
IUUC-Gac-041287	Gasterosteus aculeatus	50.40	1.00e-107	382.00
IUUC-Ggo-045296	Gorilla gorilla	83.11	0.00e+00	644.00
IUUC-Hsa-046410	Homo sapiens	83.11	0.00e+00	641.00
IUUC-Itr-049046	Ictidomys tridecemlineatus	82.57	3.00e-177	614.00
IUUC-Lch-049661	Latimeria chalumnae	63.66	9.00e-130	456.00
IUUC-Loc-051770	Lepisosteus oculatus	56.42	9.00e-79	286.00
IUUC-Laf-053619	Loxodonta africana	81.97	4.00e-180	623.00
IUUC-Mcc-054764	Macaca mulatta	83.65	0.00e+00	644.00
IUUC-Meu-056252	Macropus eugenii	70.66	5.00e-105	373.00
IUUC-Mga-059846	Meleagris gallopavo	61.05	1.00e-113	402.00
IUUC-Mmr-060750	Microcebus murinus	83.92	6.00e-180	623.00
IUUC-Mdo-062994	Monodelphis domestica	67.44	2.00e-146	511.00
IUUC-Mmu-063635	Mus musculus	93.46	0.00e+00	688.00
IUUC-Mpu-066603	Mustela putorius furo	82.56	2.00e-174	604.00
IUUC-Mlu-067615	Myotis lucifugus	81.47	1.00e-172	599.00
IUUC-Nle-070126	Nomascus leucogenys	83.92	0.00e+00	649.00
IUUC-Opr-071069	Ochotona princeps	75.76	5.00e-161	560.00
IUUC-Ont-072042	Oreochromis niloticus	52.23	6.00e-109	387.00
IUUC-Oan-073655	Ornithorhynchus anatinus	73.45	2.00e-78	284.00
IUUC-Ocu-074554	Oryctolagus cuniculus	81.47	4.00e-163	566.00
IUUC-Ola-087524	Oryzias latipes	54.38	4.00e-108	384.00
IUUC-Oga-088877	Otolemur garnettii	73.37	6.00e-158	550.00
IUUC-Oar-090049	Ovis aries	81.74	0.00e+00	633.00
IUUC-Ptr-091038	Pan troglodytes	82.83	0.00e+00	639.00
IUUC-Pan-092272	Papio anubis	83.92	0.00e+00	648.00
IUUC-Psi-093373	Pelodiscus sinensis	59.20	8.00e-119	419.00
IUUC-Pfo-096647	Poecilia formosa	54.35	1.00e-108	385.00
IUUC-Pab-097879	Pongo abelii	78.47	5.00e-171	593.00
IUUC-Pca-100192	Procavia capensis	79.84	2.00e-168	585.00
IUUC-Pva-102832	Pteropus vampyrus	84.74	0.00e+00	627.00
IUUC-Sha-106913	Sarcophilus harrisii	68.60	2.00e-139	488.00
IUUC-Sar-113560	Sorex araneus	54.12	2.00e-85	309.00
IUUC-Ssc-115648	Sus scrofa	83.38	1.00e-177	615.00
IUUC-Tgu-117359	Taeniopygia guttata	63.17	2.00e-120	424.00
IUUC-Tru-117707	Takifugu rubripes	51.30	6.00e-106	377.00
IUUC-Tsy-119614	Tarsius syrichta	60.22	7.00e-124	436.00
IUUC-Tni-120445	Tetraodon nigroviridis	50.97	1.00e-107	382.00
IUUC-Tbe-128051	Tupaia belangeri	58.93	4.00e-88	317.00
IUUC-Ttr-129199	Tursiops truncatus	83.33	7.00e-176	609.00
IUUC-Vpa-130211	Vicugna pacos	85.21	1.00e-138	485.00
IUUC-Xtr-132403	Xenopus tropicalis	53.33	1.00e-109	389.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence