iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Oar-089472

Ensembl Protein ID

ENSOARP00000012226.1

UniProt Accession

W5PP50; W5PP50_SHEEP

Genbank Protein ID

ENSOARP00000012226

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AMGL01037567

Gene Name

USP38

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOARG00000011407.1	ENSOART00000012402.1	ENSOARP00000012226.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	3.00e-83	280.0	492	994

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefsgyeq 89
           tGl NlgNtCYmNSv+Q+L++ +++r+++l+ + + +n         +l+k+lq+lf+ l +++++a++pr +++a +   + f+  +q
   Q: 492  TGLINLGNTCYMNSVIQALFMATDFRRQVLSLNLNGCN---------SLMKKLQHLFAFLAHTQREAYAPRIFFEASR--PPWFTPRSQ 569
           7******************************5555554.........7***************************998..777****** PP
   S: 90   qDaqEflaflldqleeelkk...eknkpkeeeeeedkselsde........aeekkkkknkslisdlFqgqlksqikclecdnvssree 167
           qD++E+l+flld+l+ee k    +++++ +e+ + ++++l++         +       +k+li+++F+g+l+++i cl+c+++s++ e
   Q: 570  QDCSEYLRFLLDRLHEEEKIlkvQSSHKSSESPGCSETSLQEVaikaavltETHCASDGEKTLIEKMFGGKLRTHICCLNCRSTSQKVE 658
           *****************95576678888888888888888888999999988888888899**************************** PP
   S: 168  pfldlslpvpgkeetkke....................................................................... 185
            f+dlsl++  +++ +++                                                                       
   Q: 659  AFTDLSLAFCPSSSVENLsfqdpasspstqddgltqasrpgpsegpgvcnpsaiaiacdsavnermvdspdefcctedasapndsskml 747
           *********9999766669********************************************************************** PP
   S: 186  ...............slqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleL 259
                          s++d+L+ f ++e l+g+n+yyce+c ++q+aek++++++ Pe+Lil L Rfs++++ ++r+ki ++v++pl L
   Q: 748  vnkdvpqkpggettpSVTDLLNYFLAPEILTGDNQYYCENCASLQNAEKTMQITEEPEYLILTLLRFSYDQKYHVRRKILDNVSLPLVL 836
           ***************************************************************************************99 PP
   S: 260  dlspfcts..............................peekqke.....kkkYeLiavvvHsG.slssGHYvayvkn........... 301
           +l    t                               +     e      + Y L++vvvHsG s++sGHY++y++n           
   Q: 837  ELPVKRTPfsslseswsldvdftdisenlakklkpsgtE-----EacspkLVPYLLSSVVVHSGvSSESGHYYSYARNvtgtespcqtc 920
           998444445555666666666666666666666555553.....0555559************************************** PP
   S: 302  .................................ekgkWllfdDskVtevkeeevleetg....staYvlfYkrr 338
                                             +++W+lf+Ds+Vt ++ ++v++ t+    +taYvl+Ykr+
   Q: 921  pqpetlafsssrnhllgrdspttvieqdlenkdMSKEWFLFNDSRVTFTSFQSVQKITSrfpkDTAYVLLYKRQ 994
           **********999999999999999988865544555*******************999*************96 PP

Organism

Ovis aries

Protein Sequence
(Fasta)

GGGGGGRSRC CCCCAPGSPP PRGSPGPPRG RGHRLLTPWP GPCCVATMDK ILEGLVSSSH 60
PLPLKRMIVR KVVESAEHWL DEAQCEAMFD LTTRLILEGQ APFQRQVGHQ VLEAYARYHR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGCGGCGGTG GCGGTGGTCG GTCCCGCTGC TGCTGCTGCT GCGCTCCAGG TTCGCCTCCG 60
CCCCGGGGCT CTCCTGGCCC ACCTCGGGGC CGTGGCCACC GGCTCCTCAC CCCCTGGCCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR033840--USP38
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002174	Ailuropoda melanoleuca	88.85	0.00e+00	1737.00
IUUC-Apl-003435	Anas platyrhynchos	73.19	0.00e+00	1191.00
IUUC-Aca-004556	Anolis carolinensis	67.59	0.00e+00	1189.00
IUUC-Ame-010616	Astyanax mexicanus	59.48	0.00e+00	1119.00
IUUC-Bta-013544	Bos taurus	95.29	0.00e+00	1880.00
IUUC-Cja-018745	Callithrix jacchus	87.19	0.00e+00	1710.00
IUUC-Cfa-020434	Canis familiaris	86.08	0.00e+00	1677.00
IUUC-Cpo-021666	Cavia porcellus	87.13	0.00e+00	1648.00
IUUC-Csa-023965	Chlorocebus sabaeus	89.35	0.00e+00	1810.00
IUUC-Cho-024809	Choloepus hoffmanni	78.73	0.00e+00	1144.00
IUUC-Csv-026333	Ciona savignyi	42.53	1.00e-30	125.00
IUUC-Dre-028338	Danio rerio	60.13	0.00e+00	1140.00
IUUC-Dno-029372	Dasypus novemcinctus	87.91	0.00e+00	1727.00
IUUC-Dor-030752	Dipodomys ordii	84.45	0.00e+00	1147.00
IUUC-Ete-032588	Echinops telfairi	76.22	0.00e+00	1037.00
IUUC-Eca-034416	Equus caballus	90.81	0.00e+00	1816.00
IUUC-Eeu-035132	Erinaceus europaeus	70.24	0.00e+00	1289.00
IUUC-Fca-036137	Felis catus	89.53	0.00e+00	1786.00
IUUC-Fal-037297	Ficedula albicollis	72.38	0.00e+00	1363.00
IUUC-Gmo-038727	Gadus morhua	61.84	0.00e+00	931.00
IUUC-Gga-041091	Gallus gallus	71.52	0.00e+00	1325.00
IUUC-Gac-042082	Gasterosteus aculeatus	61.06	0.00e+00	1048.00
IUUC-Ggo-045376	Gorilla gorilla	83.98	0.00e+00	1660.00
IUUC-Hsa-046444	Homo sapiens	89.16	0.00e+00	1780.00
IUUC-Itr-047976	Ictidomys tridecemlineatus	88.25	0.00e+00	1764.00
IUUC-Lch-050500	Latimeria chalumnae	69.05	0.00e+00	1312.00
IUUC-Loc-052625	Lepisosteus oculatus	63.33	0.00e+00	1208.00
IUUC-Laf-053689	Loxodonta africana	89.22	0.00e+00	1754.00
IUUC-Mcc-055286	Macaca mulatta	89.16	0.00e+00	1757.00
IUUC-Mga-059905	Meleagris gallopavo	71.68	0.00e+00	1164.00
IUUC-Mmr-061397	Microcebus murinus	89.73	0.00e+00	1767.00
IUUC-Mdo-062833	Monodelphis domestica	82.20	0.00e+00	1658.00
IUUC-Mmu-063157	Mus musculus	85.70	0.00e+00	1709.00
IUUC-Mpu-066434	Mustela putorius furo	90.02	0.00e+00	1777.00
IUUC-Mlu-068178	Myotis lucifugus	87.90	0.00e+00	1694.00
IUUC-Nle-070153	Nomascus leucogenys	88.58	0.00e+00	1713.00
IUUC-Ont-072330	Oreochromis niloticus	60.39	0.00e+00	1127.00
IUUC-Oan-072709	Ornithorhynchus anatinus	77.36	0.00e+00	1190.00
IUUC-Ocu-074832	Oryctolagus cuniculus	89.35	0.00e+00	1755.00
IUUC-Ola-087003	Oryzias latipes	55.73	1.00e-46	179.00
IUUC-Oga-088517	Otolemur garnettii	85.65	0.00e+00	1711.00
IUUC-Ptr-090996	Pan troglodytes	88.87	0.00e+00	1773.00
IUUC-Pan-091837	Papio anubis	87.32	0.00e+00	1733.00
IUUC-Psi-093236	Pelodiscus sinensis	72.64	0.00e+00	1080.00
IUUC-Pma-094349	Petromyzon marinus	50.68	0.00e+00	892.00
IUUC-Pfo-097193	Poecilia formosa	60.18	0.00e+00	1082.00
IUUC-Pab-098710	Pongo abelii	88.95	0.00e+00	1779.00
IUUC-Pca-100794	Procavia capensis	80.15	0.00e+00	1563.00
IUUC-Pva-102722	Pteropus vampyrus	89.36	0.00e+00	1752.00
IUUC-Rno-105743	Rattus norvegicus	85.78	0.00e+00	1694.00
IUUC-Sha-106563	Sarcophilus harrisii	80.65	0.00e+00	1321.00
IUUC-Sar-113533	Sorex araneus	81.32	0.00e+00	1048.00
IUUC-Ssc-116259	Sus scrofa	80.62	0.00e+00	1495.00
IUUC-Tgu-117475	Taeniopygia guttata	72.13	0.00e+00	1228.00
IUUC-Tru-118623	Takifugu rubripes	59.26	0.00e+00	1064.00
IUUC-Tsy-119250	Tarsius syrichta	87.22	0.00e+00	1360.00
IUUC-Tni-120441	Tetraodon nigroviridis	58.21	0.00e+00	1045.00
IUUC-Tbe-127936	Tupaia belangeri	79.73	0.00e+00	1518.00
IUUC-Ttr-128483	Tursiops truncatus	78.38	0.00e+00	1347.00
IUUC-Vpa-130303	Vicugna pacos	92.32	0.00e+00	993.00
IUUC-Xtr-132773	Xenopus tropicalis	69.41	0.00e+00	1311.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence