iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSDARG00000076303.4	ENSDART00000142076.1	ENSDARP00000116590.1
ENSDARG00000076303.4	ENSDART00000131963.1	ENSDARP00000113093.1
ENSDARG00000076303.4	ENSDART00000075624.5	ENSDARP00000070106.4

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	1.50e-109	367.2	242	948

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrellle.kkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefsgye 88
           +Gl+NlgNtC+mNS+LQcLsn+p+l+e++l+  + e+ln +np ++kge++++++++++++w++++ +v pr ++++++++a++f gy+
   Q: 242  CGLTNLGNTCFMNSALQCLSNTPPLTEYFLKnLYLEELNFSNPLGMKGEIAEAYADVIKQMWSGRHYSVVPRVFKTKVGHFASQFLGYQ 330
           7*****************************999******************************************************** PP
   S: 89   qqDaqEflaflldqleeelkkeknkpkeeeeeedkselsde...aeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlsl 174
           q+D+qE+l+flld+l+e+l++ k+k++ e++++d +  ++    a++++ ++n+s+i+d+F+g +ks+++c+ec++vs++++pf++ls+
   Q: 331  QHDSQELLSFLLDGLHEDLNRVKKKEYIELRDADGRPDQEVaeeAWRNHLRRNDSVIVDTFHGLFKSTLVCPECNKVSVTFDPFCYLSV 419
           *****************************999984433333555********************************************* PP
   S: 175  pvpgkeetkke.............................................................................. 185
           p+p ++e+ +e                                                                              
   Q: 420  PLPVSKERVMEvfyvsldptakptqyrlivpkagrvldlctalsqatgvppnqmtvtdvfnhrfyriyqsdeslscildrddifvyqls 508
           ******99999****************************************************************************** PP
   S: 186  ......................................................................................... 185
                                                                                                    
   Q: 509  sgcvdedsdevvlsiymrershyrdygsgsnsygtslfghplrmsvprahctpehlyqlllerlaryvrpldpseeveeeeeddeeely 597
           ***************************************************************************************** PP
   S: 186  ......................................................................................... 185
                                                                                                    
   Q: 598  kaqtngvsddegeedseeagsskkeeeprasnevneqnngqseaspssegeeraeeeessseqergssteegqsacgstdttdgdqsag 686
           ***************************************************************************************** PP
   S: 186  ......................................................................................... 185
                                                                                                    
   Q: 687  aepsgkeededeeeedgeeaasctpankrhpgrrryterrkkalftiqavnsngttergmaeaggsisfssqpyiaidwdpdmkkkyyn 775
           ***************************************************************************************** PP
   S: 186  ......................slqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkk 252
                                 +lq+c+e ft+ e+le+en +yc++ck++q a+kkl+l++lPevLi+hLkRfs+++  +srek+++ 
   Q: 776  eneaekyikhqsmdvphqqttvQLQECIELFTTVETLEEENPWYCPTCKRHQLATKKLDLWSLPEVLIIHLKRFSYTK--YSREKLDTI 862
           **************************************************************************9976..799****** PP
   S: 253  vefple.Ldlspfctspeekqke.kkkYeLiavvvHsGslssGHYvayvknekgk.WllfdDskVtevkeeevleetgstaYvlfYkrr 338
           vefpl+ Ld s f+ +++ +++e ++ Y+Li+v +H+G+l+ GHY++y++n++++ W++fdDskVt  +ee++++   s aY+lfY+r+
   Q: 863  VEFPLRdLDFSGFLLKKTVNSTEpPCPYDLISVSNHYGGLRDGHYTSYARNKDNGqWYYFDDSKVTYAREEQIVT---SAAYLLFYQRQ 948
           ************99998877666599*************************66555*******************...*********96 PP

Organism

Danio rerio

Protein Sequence
(Fasta)

MAANCSAGSA TEPPGLETQW REIDNLNQQQ LRAGDSWYLL DKRWYDQWKE YVDTGDQNST 60
SYPGKIDNTE LYEDLDSYRL KERLTENDDF ILVPAEAWRK LLSWYDMMDN QPPLERKVVD 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TCCTACTTCC TTCGTCAAAA CATTCCGGTG TGTCTATGCG GCTCTAACGG CGCTTTTCGG 60
ATTTTAGGAG TGATTATGGC TGCGAACTGC AGCGCCGGTT CGGCCACAGA GCCTCCGGGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1267--Proteomics identification
KW-1185--Reference proteome

Interpro

IPR006615--Pept_C19_DUSP
IPR001394--Peptidase_C19_UCH
IPR028135--Ub_USP-typ
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS51283--DUSP
PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF06337--DUSP
PF14836--Ubiquitin_3
PF00443--UCH

SMART

SM00695--DUSP

Gene Ontology

GO:0005634--C:nucleus
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

KEGG

dre:568334

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001760	Ailuropoda melanoleuca	62.52	0.00e+00	733.00
IUUC-Aca-004532	Anolis carolinensis	67.48	0.00e+00	819.00
IUUC-Ame-011858	Astyanax mexicanus	70.96	0.00e+00	1254.00
IUUC-Bta-013284	Bos taurus	63.07	0.00e+00	754.00
IUUC-Cja-019746	Callithrix jacchus	59.97	0.00e+00	731.00
IUUC-Cfa-020134	Canis familiaris	63.46	0.00e+00	760.00
IUUC-Cpo-022535	Cavia porcellus	58.49	0.00e+00	710.00
IUUC-Csa-023828	Chlorocebus sabaeus	60.14	0.00e+00	733.00
IUUC-Cne-026852	Cryptococcus neoformans	47.27	4.00e-70	260.00
IUUC-Dor-030384	Dipodomys ordii	59.51	0.00e+00	712.00
IUUC-Ete-033029	Echinops telfairi	80.24	2.00e-122	433.00
IUUC-Eca-033271	Equus caballus	62.52	0.00e+00	730.00
IUUC-Fca-036012	Felis catus	62.06	0.00e+00	746.00
IUUC-Gmo-038697	Gadus morhua	66.22	0.00e+00	778.00
IUUC-Gac-042574	Gasterosteus aculeatus	67.77	0.00e+00	791.00
IUUC-Hsa-046551	Homo sapiens	60.14	0.00e+00	733.00
IUUC-Itr-048915	Ictidomys tridecemlineatus	59.93	0.00e+00	735.00
IUUC-Kpa-049332	Komagataella pastoris	33.99	4.00e-72	266.00
IUUC-Mcc-054881	Macaca mulatta	59.97	0.00e+00	732.00
IUUC-Meu-056749	Macropus eugenii	68.03	0.00e+00	778.00
IUUC-Mla-058848	Melampsora laricipopulina	48.16	3.00e-70	261.00
IUUC-Mvi-060324	Microbotryum violaceum	31.85	2.00e-78	288.00
IUUC-Mmr-061400	Microcebus murinus	61.34	0.00e+00	741.00
IUUC-Mdo-062470	Monodelphis domestica	71.28	0.00e+00	725.00
IUUC-Mmu-063241	Mus musculus	60.78	0.00e+00	734.00
IUUC-Mlu-066961	Myotis lucifugus	59.79	0.00e+00	706.00
IUUC-Nle-069284	Nomascus leucogenys	60.14	0.00e+00	735.00
IUUC-Ont-071847	Oreochromis niloticus	76.11	0.00e+00	897.00
IUUC-Oan-073387	Ornithorhynchus anatinus	66.38	0.00e+00	786.00
IUUC-Ocu-074066	Oryctolagus cuniculus	60.35	0.00e+00	725.00
IUUC-Ola-086500	Oryzias latipes	63.84	0.00e+00	1158.00
IUUC-Oga-088424	Otolemur garnettii	61.40	0.00e+00	742.00
IUUC-Oar-089732	Ovis aries	63.07	0.00e+00	721.00
IUUC-Pan-092292	Papio anubis	60.31	0.00e+00	733.00
IUUC-Pfo-096414	Poecilia formosa	76.06	0.00e+00	966.00
IUUC-Pca-100851	Procavia capensis	64.50	0.00e+00	676.00
IUUC-Pva-103244	Pteropus vampyrus	62.24	0.00e+00	739.00
IUUC-Ptt-103847	Puccinia triticina	41.64	8.00e-64	239.00
IUUC-Rno-105100	Rattus norvegicus	60.78	0.00e+00	736.00
IUUC-Sha-107502	Sarcophilus harrisii	65.65	0.00e+00	761.00
IUUC-Sja-107752	Schizosaccharomyces japonicus	36.18	3.00e-84	306.00
IUUC-Spo-108291	Schizosaccharomyces pombe	34.10	6.00e-78	285.00
IUUC-Smo-109356	Selaginella moellendorffii	47.71	2.00e-78	286.00
IUUC-Tru-117788	Takifugu rubripes	71.52	0.00e+00	917.00
IUUC-Tsy-119414	Tarsius syrichta	56.47	0.00e+00	670.00
IUUC-Tni-120799	Tetraodon nigroviridis	68.25	0.00e+00	867.00
IUUC-Tre-121888	Trichoderma reesei	36.96	1.00e-63	239.00
IUUC-Tvi-122422	Trichoderma virens	41.39	1.00e-57	219.00
IUUC-Tae-125295	Triticum aestivum	36.77	4.00e-100	359.00
IUUC-Tbe-128081	Tupaia belangeri	61.15	0.00e+00	683.00
IUUC-Ttr-128502	Tursiops truncatus	59.09	0.00e+00	682.00
IUUC-Xma-133838	Xiphophorus maculatus	80.93	5.00e-180	625.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence