iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Loc-052180

Ensembl Protein ID

ENSLOCP00000015459.1

UniProt Accession

W5N4A0; W5N4A0_LEPOC

Genbank Protein ID

ENSLOCP00000015459

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AHAT01001831

Gene Name

USP53

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLOCG00000012556.1	ENSLOCT00000015488.1	ENSLOCP00000015459.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	1.80e-23	83.4	33	351

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 2    GlkNl..gNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaee...fs 85
           Gl N   +N+C++NS++Q+L+++  +r+ l +   + +        ++++ ++l+++f+++++s+++a    +l +al+++ +    f+
   Q: 33   GLLNEpgQNSCFLNSAVQVLWQLDVFRRSLRQLPGHVCLG------EACIFCALKSIFSQFQHSRERALPSDNLRHALAETFKDeqrFQ 115
           55555447************************55555554......57**************999999999998888887654323399 PP
   S: 86   gyeqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlsl 174
                Da E+++ +l++++ ++                     + e +   +++++ ++ F ++l +q++c +c+ +s    pf++l  
   Q: 116  LGFMDDAAECFENILERIHLHI-------------------VPDTETDVCVSKSCITHQKFAMTLYEQCVCRSCGASSDPL-PFTELVH 184
           9999******************...................122346788999**********************999665.9****** PP
   S: 175  pvpgkeetkke.........slqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkve 254
            v+    +++             d++ +  ++ +  g+ +   ++c ++ + ++   l ++Pe+ ++ + +    e+ +  e + +++ 
   Q: 185  YVSTTALCQQVdlfleknerLRYDMFGELLQAASTIGDLRNCPSNCGQRIKIRRV--LMNCPEIVTIGFVWD--AEQSDLTEDVIRSLG 269
           ***8888766688888888545688888888888888887888888887754444..6688******99888..455556655655555 PP
   S: 255  fpleLdlspfctspeekqkekkkYeLiavvvHsGslssGHYvayvknekgk.WllfdDskVtev..keeevleetg...staYvlfYk 336
              +L+ls    + +++q++k+   L+++++++      HY+a+++++k + W+ fdD +V+ev  k+++v++++     ++ +lfY 
   Q: 270  --PQLNLSGLFYRVTDEQAKKTDLILVGMICYTS----KHYCAFAYHTKSSkWVFFDDATVKEVgsKWKDVVSKCIrghFQPLLLFYS 351
           ..3699998777777778889***********87....9********77767***********9767899999776888899999996 PP

Organism

Lepisosteus oculatus

Protein Sequence
(Fasta)

NQMAWVKFFK KQGGNLGKSY QPGSMLSLAP TKGLLNEPGQ NSCFLNSAVQ VLWQLDVFRR 60
SLRQLPGHVC LGEACIFCAL KSIFSQFQHS RERALPSDNL RHALAETFKD EQRFQLGFMD 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AGTCACCAAT GTGATGTTGT CCAATGTGTG GAACTGCTGT CCTCAAGCTT CCTTATGGAT 60
GAACTTTGGA ACTTTCTTCT GTTGATTACC AACAACGGCA AATGATGTAG AGAAGTGGGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR028889--USP_dom

PROSITE

PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0016579--P:protein deubiquitination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002136	Ailuropoda melanoleuca	59.51	0.00e+00	835.00
IUUC-Atr-002451	Amborella trichopoda	31.38	3.00e-41	164.00
IUUC-Apl-003843	Anas platyrhynchos	60.14	0.00e+00	853.00
IUUC-Aca-004689	Anolis carolinensis	60.25	0.00e+00	835.00
IUUC-Aly-005859	Arabidopsis lyrata	30.70	3.00e-40	161.00
IUUC-Ame-010673	Astyanax mexicanus	55.77	0.00e+00	1000.00
IUUC-Bta-012434	Bos taurus	59.44	0.00e+00	833.00
IUUC-Cja-019625	Callithrix jacchus	60.38	0.00e+00	868.00
IUUC-Cfa-020038	Canis familiaris	60.25	0.00e+00	846.00
IUUC-Cpo-021503	Cavia porcellus	59.37	0.00e+00	850.00
IUUC-Csa-024021	Chlorocebus sabaeus	59.75	0.00e+00	857.00
IUUC-Cho-024769	Choloepus hoffmanni	56.60	0.00e+00	735.00
IUUC-Dre-028438	Danio rerio	56.54	0.00e+00	812.00
IUUC-Dno-029317	Dasypus novemcinctus	58.57	0.00e+00	821.00
IUUC-Dor-030249	Dipodomys ordii	80.43	0.00e+00	670.00
IUUC-Ete-032403	Echinops telfairi	58.39	0.00e+00	844.00
IUUC-Eca-033216	Equus caballus	60.60	0.00e+00	842.00
IUUC-Eeu-035319	Erinaceus europaeus	51.67	6.00e-132	465.00
IUUC-Fca-036414	Felis catus	58.82	0.00e+00	838.00
IUUC-Fal-036886	Ficedula albicollis	51.65	0.00e+00	858.00
IUUC-Gmo-038617	Gadus morhua	83.70	0.00e+00	648.00
IUUC-Gga-040930	Gallus gallus	59.76	0.00e+00	870.00
IUUC-Gac-041515	Gasterosteus aculeatus	84.39	0.00e+00	662.00
IUUC-Gma-043273	Glycine max	31.38	7.00e-41	163.00
IUUC-Ggo-045573	Gorilla gorilla	60.30	0.00e+00	862.00
IUUC-Hsa-046741	Homo sapiens	60.03	0.00e+00	863.00
IUUC-Itr-048229	Ictidomys tridecemlineatus	56.55	0.00e+00	775.00
IUUC-Lch-049932	Latimeria chalumnae	62.33	0.00e+00	865.00
IUUC-Lpe-051572	Leersia perrieri	31.74	2.00e-41	165.00
IUUC-Laf-054545	Loxodonta africana	59.73	0.00e+00	854.00
IUUC-Mcc-054918	Macaca mulatta	60.03	0.00e+00	864.00
IUUC-Meu-056802	Macropus eugenii	54.66	0.00e+00	726.00
IUUC-Mtr-058682	Medicago truncatula	28.57	2.00e-35	145.00
IUUC-Mga-059684	Meleagris gallopavo	50.77	0.00e+00	828.00
IUUC-Mmr-061644	Microcebus murinus	77.13	7.00e-164	569.00
IUUC-Mdo-062636	Monodelphis domestica	58.50	0.00e+00	825.00
IUUC-Mmu-063910	Mus musculus	59.21	0.00e+00	816.00
IUUC-Mac-064469	Musa acuminata	32.20	3.00e-19	91.70
IUUC-Mpu-065796	Mustela putorius furo	54.75	0.00e+00	763.00
IUUC-Nle-069276	Nomascus leucogenys	59.89	0.00e+00	825.00
IUUC-Opr-070545	Ochotona princeps	48.45	7.00e-112	398.00
IUUC-Ont-072449	Oreochromis niloticus	61.00	0.00e+00	826.00
IUUC-Oan-073493	Ornithorhynchus anatinus	53.67	5.00e-165	575.00
IUUC-Ocu-074445	Oryctolagus cuniculus	57.47	0.00e+00	827.00
IUUC-Obr-076268	Oryza brachyantha	32.15	6.00e-44	173.00
IUUC-Ola-087574	Oryzias latipes	74.81	4.00e-178	617.00
IUUC-Oga-087977	Otolemur garnettii	56.48	0.00e+00	760.00
IUUC-Oar-089584	Ovis aries	59.02	0.00e+00	836.00
IUUC-Ptr-091610	Pan troglodytes	60.03	0.00e+00	855.00
IUUC-Pan-091828	Papio anubis	55.86	0.00e+00	755.00
IUUC-Psi-093643	Pelodiscus sinensis	61.26	0.00e+00	890.00
IUUC-Ppa-095930	Physcomitrella patens	32.96	3.00e-41	165.00
IUUC-Pfo-096829	Poecilia formosa	66.35	0.00e+00	699.00
IUUC-Pab-098190	Pongo abelii	60.38	0.00e+00	858.00
IUUC-Pop-099539	Populus trichocarpa	30.32	2.00e-38	155.00
IUUC-Ppe-101918	Prunus persica	29.91	5.00e-41	164.00
IUUC-Pva-102372	Pteropus vampyrus	57.28	0.00e+00	783.00
IUUC-Sha-107092	Sarcophilus harrisii	61.20	0.00e+00	836.00
IUUC-Sly-110975	Solanum lycopersicum	30.90	9.00e-40	159.00
IUUC-Stu-112904	Solanum tuberosum	30.14	3.00e-37	151.00
IUUC-Sar-113376	Sorex araneus	85.19	4.00e-101	362.00
IUUC-Ssc-115969	Sus scrofa	60.28	0.00e+00	834.00
IUUC-Tgu-117134	Taeniopygia guttata	59.78	0.00e+00	863.00
IUUC-Tru-117981	Takifugu rubripes	76.98	0.00e+00	648.00
IUUC-Tsy-119297	Tarsius syrichta	67.08	9.00e-160	557.00
IUUC-Tni-120116	Tetraodon nigroviridis	83.24	0.00e+00	646.00
IUUC-Tbe-127607	Tupaia belangeri	58.61	0.00e+00	820.00
IUUC-Ttr-128647	Tursiops truncatus	58.47	0.00e+00	783.00
IUUC-Vpa-130288	Vicugna pacos	55.05	0.00e+00	749.00
IUUC-Vvi-131652	Vitis vinifera	30.79	3.00e-40	161.00
IUUC-Xtr-132277	Xenopus tropicalis	52.81	0.00e+00	685.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence