iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mdo-062362

Ensembl Protein ID

ENSMODP00000024495.2

UniProt Accession

F6XPG4; F6XPG4_MONDO

Protein Name

Uncharacterized protein

Gene Name

PHF19

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMODG00000019637.3	ENSMODT00000024931.3	ENSMODP00000024495.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	1.20e-08	35.1	97	148

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/PHD

   S: 3    vClvCgeggedek.slveCekCrewfHpaClkls.veeelpnsekwiCpkCr 52
            C +C  ++++   +++ C kC   +H++C+ ++  ++e p  ++w+C++C 
   Q: 97   KCNICLGKTSGPLnEILICGKCGLGYHQQCHIPTaSSTEGPLLTPWFCRRCI 148
           5999*99888764589******************44555666777******6 PP

Organism

Monodelphis domestica

Protein Sequence
(Fasta)

KLMENLSLES EIQDDCGPPR AAGAPTKSRN NFKDLMVKLT EGQYVLCRWT DGLYYLGKIK 60
RVSSSKQSCL VTFEDNSKYW VLWKDIQHAG VPGEEPKCNI CLGKTSGPLN EILICGKCGL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CCCGCATCCC TCTGTCCCCG GCTTGAGCTG GACTCCAGCT TCTTCAACTG GGGCATGGCC 60
TGGATTCCCT GCCCCTTGAG AGACTGATAG ACAGACGGAC AGAGGGACGG ACAGACAGAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR025894--Mtf2_C_dom
IPR002999--Tudor
IPR019786--Zinc_finger_PHD-type_CS
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS01359--ZF_PHD_1
PS50016--ZF_PHD_2

Pfam

PF14061--Mtf2_C
PF00628--PHD

SMART

SM00249--PHD
SM00333--TUDOR

Gene Ontology

GO:0035098--C:ESC/E(Z) complex
GO:0008270--F:zinc ion binding
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0061087--P:positive regulation of histone H3-K27 methylation
GO:0048863--P:stem cell differentiation
GO:0019827--P:stem cell population maintenance

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002293	Ailuropoda melanoleuca	82.83	0.00e+00	891.00
IUUC-Apl-003282	Anas platyrhynchos	75.85	4.00e-159	554.00
IUUC-Cfa-020781	Canis familiaris	67.39	0.00e+00	678.00
IUUC-Dre-028079	Danio rerio	63.73	0.00e+00	639.00
IUUC-Ete-032758	Echinops telfairi	72.28	0.00e+00	706.00
IUUC-Gmo-039321	Gadus morhua	52.17	1.00e-147	516.00
IUUC-Gac-042130	Gasterosteus aculeatus	53.68	2.00e-151	528.00
IUUC-Itr-048903	Ictidomys tridecemlineatus	79.78	0.00e+00	690.00
IUUC-Lch-050049	Latimeria chalumnae	71.24	0.00e+00	715.00
IUUC-Loc-052034	Lepisosteus oculatus	65.43	0.00e+00	656.00
IUUC-Mga-059421	Meleagris gallopavo	75.84	0.00e+00	736.00
IUUC-Mpu-065837	Mustela putorius furo	81.86	0.00e+00	877.00
IUUC-Oan-073043	Ornithorhynchus anatinus	74.09	5.00e-107	380.00
IUUC-Oga-089023	Otolemur garnettii	82.03	0.00e+00	883.00
IUUC-Pva-103007	Pteropus vampyrus	84.28	0.00e+00	784.00
IUUC-Ssc-116063	Sus scrofa	73.52	1.00e-136	478.00
IUUC-Tgu-117197	Taeniopygia guttata	80.46	2.00e-141	494.00
IUUC-Tni-120027	Tetraodon nigroviridis	53.26	2.00e-147	515.00
IUUC-Ttr-128678	Tursiops truncatus	79.36	0.00e+00	796.00
IUUC-Vpa-130085	Vicugna pacos	69.33	1.00e-55	209.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence