iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Aca-005141

UUCD1 version

UUC-AnC-00614

Ensembl Protein ID

ENSACAP00000007041.3

UniProt Accession

G1KG92; G1KG92_ANOCA

Protein Name

Uncharacterized protein

Gene Name

TRIM59

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSACAG00000007216.3	ENSACAT00000007193.3	ENSACAP00000007041.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	3.20e-08	33.9	10	60

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadClqkwpglknssskefr..........CPlCr 46
           C+iC++ f+d p+vlpC H+f+++Cl+ +     + s +f+          CP Cr
   Q: 10   CSICYSIFDD-PRVLPCSHTFCRNCLESV----LQLSSTFSiwrplrlplkCPNCR 60
           **********.**************9888....233333333556666666***98 PP

Organism

Anolis carolinensis

Protein Sequence
(Fasta)

MHHFEEELTC SICYSIFDDP RVLPCSHTFC RNCLESVLQL SSTFSIWRPL RLPLKCPNCR 60
SIVEIPPSGT DSLPVNYALK AIIEKYQRED HPDVATCNEH YRQPLNVYCL LDRKLVCGQC 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGCATCACT TCGAAGAGGA GTTAACATGT TCCATTTGCT ATAGTATATT TGATGACCCC 60
CGTGTACTGC CATGCTCTCA TACATTTTGT CGAAATTGTT TGGAAAGTGT TCTTCAGCTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR027370--Znf-RING_LisH
IPR000315--Znf_B-box
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS50119--ZF_BBOX
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF00643--zf-B_box
PF13445--zf-RING_UBOX

SMART

SM00184--RING

Gene Ontology

GO:0005813--C:centrosome
GO:0005929--C:cilium
GO:0005783--C:endoplasmic reticulum
GO:0016021--C:integral component of membrane
GO:0030992--C:intraciliary transport particle B
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0060271--P:cilium assembly
GO:0045087--P:innate immune response
GO:0043124--P:negative regulation of I-kappaB kinase/NF-kappaB signaling
GO:0046597--P:negative regulation of viral entry into host cell

KEGG

acs:100564775

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002249	Ailuropoda melanoleuca	58.52	3.00e-135	474.00
IUUC-Apl-003996	Anas platyrhynchos	62.19	4.00e-134	471.00
IUUC-Ame-011353	Astyanax mexicanus	55.23	5.00e-105	374.00
IUUC-Bta-013440	Bos taurus	60.16	4.00e-132	464.00
IUUC-Cfa-021168	Canis familiaris	58.71	9.00e-138	483.00
IUUC-Cpo-021702	Cavia porcellus	54.50	3.00e-120	424.00
IUUC-Csa-024141	Chlorocebus sabaeus	57.28	7.00e-124	436.00
IUUC-Dre-028408	Danio rerio	41.12	6.00e-88	317.00
IUUC-Dno-029180	Dasypus novemcinctus	57.28	1.00e-132	465.00
IUUC-Eca-034357	Equus caballus	57.43	5.00e-134	470.00
IUUC-Fca-036287	Felis catus	59.01	6.00e-137	480.00
IUUC-Gga-040739	Gallus gallus	63.21	2.00e-153	534.00
IUUC-Ggo-045307	Gorilla gorilla	57.32	7.00e-131	459.00
IUUC-Hsa-045690	Homo sapiens	58.02	6.00e-132	463.00
IUUC-Itr-048230	Ictidomys tridecemlineatus	56.79	6.00e-134	470.00
IUUC-Laf-054522	Loxodonta africana	57.28	4.00e-131	460.00
IUUC-Mcc-055145	Macaca mulatta	58.02	8.00e-133	466.00
IUUC-Mmr-061197	Microcebus murinus	57.53	2.00e-135	475.00
IUUC-Mmu-064217	Mus musculus	56.69	2.00e-129	455.00
IUUC-Mpu-065691	Mustela putorius furo	58.77	8.00e-137	479.00
IUUC-Mlu-067742	Myotis lucifugus	55.07	2.00e-126	445.00
IUUC-Nle-069722	Nomascus leucogenys	58.02	1.00e-137	482.00
IUUC-Oan-073382	Ornithorhynchus anatinus	54.73	3.00e-122	431.00
IUUC-Oar-089206	Ovis aries	56.73	5.00e-136	477.00
IUUC-Pan-092189	Papio anubis	58.27	2.00e-133	468.00
IUUC-Psi-093523	Pelodiscus sinensis	69.46	8.00e-156	542.00
IUUC-Pma-094162	Petromyzon marinus	38.24	5.00e-51	194.00
IUUC-Pfo-096032	Poecilia formosa	50.16	1.00e-95	342.00
IUUC-Pva-103089	Pteropus vampyrus	57.57	2.00e-127	448.00
IUUC-Rno-105440	Rattus norvegicus	56.79	3.00e-132	464.00
IUUC-Ssc-115809	Sus scrofa	58.02	4.00e-127	447.00
IUUC-Tru-118402	Takifugu rubripes	45.88	3.00e-96	345.00
IUUC-Tni-119737	Tetraodon nigroviridis	44.69	5.00e-87	313.00
IUUC-Ttr-128921	Tursiops truncatus	58.56	1.00e-130	459.00
IUUC-Vpa-130397	Vicugna pacos	57.28	3.00e-134	471.00
IUUC-Xtr-132752	Xenopus tropicalis	48.39	2.00e-90	325.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence