iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Fal-037311

Ensembl Protein ID

ENSFALP00000007577.1

UniProt Accession

U3JXS3; U3JXS3_FICAL

Genbank Protein ID

ENSFALP00000007577

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AGTO01020425

Gene Name

KLHL22

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSFALG00000007263.1	ENSFALT00000007609.1	ENSFALP00000007577.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB	1.90e-18	66.3	48	112
E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box	1.40e-07	30.8	147	177

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB

   S: 2    DvilvvggeeffahkivLaasSsvFyalflmeleesksklmveikdvqpevfrallkFlYtgklde 67
           Dv+l v+++ ++ah+i Laas+++F+ +f ++l+e++ +++v+i+++++ ++  +l+F+Yt++l++
   Q: 48   DVVLRVEDKPIEAHRILLAASCDYFRGMFAGGLREME-QEEVHIHGISYNAMCKILNFIYTSELEL 112
           9***********************************8.*************************986 PP

E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box

   S: 2    eNclgilrfAdlydcpdLkdaaldfilkhFk 32
           eN l+++r+Ad+yd+++L ++ +++ilk+F+
   Q: 147  ENILDVYRLADHYDLRHLSEQLDSYILKNFT 177
           8*****************************7 PP

Organism

Ficedula albicollis

Protein Sequence
(Fasta)

MAEEPRAQRA APEAPRPPRG SSTYRSAEHS QALLRGLLSL RDSSILFDVV LRVEDKPIEA 60
HRILLAASCD YFRGMFAGGL REMEQEEVHI HGISYNAMCK ILNFIYTSEL ELSVNSVQET 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TTGGTAATGG GTTGGGAAGT GAAACTCTTG CTAAGAAAAA AAATACCCAT GTGACACATA 60
CTCTGATATT GGTCTGAAAA CCCAGGGGTC AGAATACCTG TTTTTGGAAA ACCTTATTCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0880--Kelch repeat
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR011705--BACK
IPR017096--BTB-kelch_protein
IPR000210--BTB/POZ_dom
IPR015915--Kelch-typ_b-propeller
IPR006652--Kelch_1
IPR030575--KLHL22
IPR011333--SKP1/BTB/POZ

PROSITE

PS50097--BTB

Pfam

PF07707--BACK
PF00651--BTB
PF01344--Kelch_1

SMART

SM00875--BACK
SM00225--BTB
SM00612--Kelch

Gene Ontology

GO:0005813--C:centrosome
GO:0031463--C:Cul3-RING ubiquitin ligase complex
GO:0005737--C:cytoplasm
GO:0072686--C:mitotic spindle
GO:0005827--C:polar microtubule
GO:0051301--P:cell division
GO:0000070--P:mitotic sister chromatid segregation
GO:0007094--P:mitotic spindle assembly checkpoint
GO:0006513--P:protein monoubiquitination

KEGG

fab:101809000

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002097	Ailuropoda melanoleuca	77.74	0.00e+00	1013.00
IUUC-Apl-004081	Anas platyrhynchos	94.36	0.00e+00	1259.00
IUUC-Aca-005015	Anolis carolinensis	66.13	0.00e+00	863.00
IUUC-Ame-011712	Astyanax mexicanus	60.23	0.00e+00	758.00
IUUC-Bta-012594	Bos taurus	77.74	0.00e+00	1025.00
IUUC-Cja-019752	Callithrix jacchus	79.57	0.00e+00	858.00
IUUC-Cfa-020884	Canis familiaris	77.90	0.00e+00	1033.00
IUUC-Cpo-021711	Cavia porcellus	78.06	0.00e+00	1032.00
IUUC-Csa-023211	Chlorocebus sabaeus	78.68	0.00e+00	1041.00
IUUC-Dre-028395	Danio rerio	61.23	0.00e+00	787.00
IUUC-Dno-030096	Dasypus novemcinctus	79.67	0.00e+00	1042.00
IUUC-Dor-030709	Dipodomys ordii	78.15	1.00e-166	580.00
IUUC-Eca-033388	Equus caballus	77.74	0.00e+00	1033.00
IUUC-Eeu-034616	Erinaceus europaeus	70.40	0.00e+00	903.00
IUUC-Fca-035815	Felis catus	78.06	0.00e+00	1035.00
IUUC-Gmo-039571	Gadus morhua	53.74	2.00e-165	575.00
IUUC-Gga-040992	Gallus gallus	94.20	0.00e+00	1258.00
IUUC-Gac-042041	Gasterosteus aculeatus	58.71	0.00e+00	718.00
IUUC-Ggo-045141	Gorilla gorilla	74.29	0.00e+00	979.00
IUUC-Hsa-045984	Homo sapiens	78.68	0.00e+00	1043.00
IUUC-Itr-048890	Ictidomys tridecemlineatus	77.59	0.00e+00	1035.00
IUUC-Lch-049700	Latimeria chalumnae	62.06	0.00e+00	758.00
IUUC-Loc-052141	Lepisosteus oculatus	63.05	0.00e+00	843.00
IUUC-Laf-053487	Loxodonta africana	78.76	0.00e+00	1049.00
IUUC-Mcc-054682	Macaca mulatta	80.16	0.00e+00	852.00
IUUC-Meu-055937	Macropus eugenii	71.41	0.00e+00	931.00
IUUC-Mga-059953	Meleagris gallopavo	94.20	0.00e+00	1258.00
IUUC-Mmr-061743	Microcebus murinus	78.06	0.00e+00	1035.00
IUUC-Mdo-062328	Monodelphis domestica	78.36	0.00e+00	1031.00
IUUC-Mmu-063979	Mus musculus	79.61	0.00e+00	1019.00
IUUC-Mpu-066750	Mustela putorius furo	78.06	0.00e+00	1034.00
IUUC-Mlu-066960	Myotis lucifugus	78.06	0.00e+00	1037.00
IUUC-Nle-069690	Nomascus leucogenys	80.21	0.00e+00	952.00
IUUC-Opr-071059	Ochotona princeps	73.86	0.00e+00	949.00
IUUC-Ont-072004	Oreochromis niloticus	60.21	0.00e+00	723.00
IUUC-Oan-073172	Ornithorhynchus anatinus	63.97	0.00e+00	762.00
IUUC-Ocu-074310	Oryctolagus cuniculus	76.87	2.00e-125	441.00
IUUC-Ola-086599	Oryzias latipes	57.90	0.00e+00	724.00
IUUC-Oga-087980	Otolemur garnettii	77.39	0.00e+00	1032.00
IUUC-Oar-089956	Ovis aries	65.07	0.00e+00	746.00
IUUC-Ptr-090598	Pan troglodytes	80.28	0.00e+00	957.00
IUUC-Pan-092387	Papio anubis	80.35	0.00e+00	856.00
IUUC-Psi-093484	Pelodiscus sinensis	86.18	0.00e+00	1120.00
IUUC-Pma-094224	Petromyzon marinus	51.59	8.00e-180	623.00
IUUC-Pfo-096149	Poecilia formosa	61.21	0.00e+00	745.00
IUUC-Pab-098097	Pongo abelii	78.53	0.00e+00	1042.00
IUUC-Pca-100118	Procavia capensis	78.11	4.00e-172	597.00
IUUC-Pva-103174	Pteropus vampyrus	76.78	2.00e-125	442.00
IUUC-Rno-105350	Rattus norvegicus	78.80	0.00e+00	998.00
IUUC-Sha-106817	Sarcophilus harrisii	79.78	2.00e-131	462.00
IUUC-Sar-113490	Sorex araneus	80.47	4.00e-163	567.00
IUUC-Ssc-115827	Sus scrofa	77.74	0.00e+00	1027.00
IUUC-Tgu-116748	Taeniopygia guttata	99.05	0.00e+00	1090.00
IUUC-Tru-118644	Takifugu rubripes	57.81	0.00e+00	736.00
IUUC-Tsy-118888	Tarsius syrichta	74.20	0.00e+00	867.00
IUUC-Tni-120060	Tetraodon nigroviridis	54.61	8.00e-180	623.00
IUUC-Ttr-129183	Tursiops truncatus	79.00	0.00e+00	942.00
IUUC-Xtr-132780	Xenopus tropicalis	72.26	0.00e+00	945.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence