iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMMUG00000000382.3	ENSMMUT00000000555.2	ENSMMUP00000000510.1
ENSMMUG00000000382.3	ENSMMUT00000058365.1	ENSMMUP00000059654.1
ENSMMUG00000000382.3	ENSMMUT00000044697.2	ENSMMUP00000037713.2
ENSMMUG00000000382.3	ENSMMUT00000073243.1	ENSMMUP00000053350.1
ENSMMUG00000000382.3	ENSMMUT00000000556.3	ENSMMUP00000000511.3
ENSMMUG00000000382.3	ENSMMUT00000066498.1	ENSMMUP00000058895.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.40e-35	120.9	476	515
UBD/Beta-Prp	1.60e-57	196.1	393	630

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf...sdtllvsGsdDgtikvWDlrtgvllks 38
           gHtdsv++++f   s ++l+++s D+t+ +WD rtg +++s
   Q: 476  GHTDSVNSIEFfpfS-NTLLTSSADKTLSIWDARTGICEQS 515
           8*********99865.899*******************996 PP

UBD/Beta-Prp

   S: 9    hksvitcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsv 97
           h++ +++ +f+p+++ lat+s d t+k+wd+ +g+++ +++gh+ +v+++++++ g++ +++s D+t k+wd+++  c  tl gh+dsv
   Q: 393  HTDWLSDCCFHPSGNTLATSSGDTTVKLWDLCKGDCILTFEGHSHAVWSCTWHSCGNFVASSSLDKTSKIWDVNSERCRCTLYGHTDSV 481
           7889999********************************************************************************** PP
   S: 98   lslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsvysl 186
            s++f+p +++l++ s+d+t+ +wd +tg c +  l gh++++n + ++p g +++s+ + ++ +lWd +    +        ++ + +
   Q: 482  NSIEFFPFSNTLLTSSADKTLSIWDARTGICEQ-SLYGHMHSINDAIFDPRGHMIASCDARGVTKLWDFRKLLPIVSIDI-GPSPGNEV 568
           *******99************************.***********************************88888888865.899***** PP
   S: 187  sfdsngkelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfspnderlvsgssDgsiriW 249
           +fds+g+ l+ +s +g + l dl++ge +++l gh++ v  v fs ++e+l sg+sDg++r W
   Q: 569  NFDSSGRVLAQASGNGVIHLLDLKSGE-IHKLMGHESEVHTVVFSHDGEILFSGGSDGTVRTW 630
           **************************9.*********************************** PP

Organism

Macaca mulatta

Protein Sequence
(Fasta)

MAAQRGTPSS AVRVLEEALG MGLTAAGDAR DTADAVAAEG AYYLEQVTIT EASEDDYEYE 60
EIPDDNFSIP EGEEDLAKAI QMAQEQATDT EILERKTVLP SKPAVPEVIE DFLCNFLIKM 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCTGCTC AGCGAGGGAC ACCGAGCTCC GCCGTGAGGG TGCTGGAAGA GGCGTTGGGC 60
ATGGGTTTGA CGGCAGCTGG GGACGCGAGG GACACGGCGG ACGCGGTGGC GGCTGAGGGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:1990716--C:axonemal central apparatus
GO:0005737--C:cytoplasm
GO:0005634--C:nucleus
GO:0097231--P:cell motility in response to calcium ion
GO:0060294--P:cilium movement involved in cell motility
GO:0051012--P:microtubule sliding
GO:0007288--P:sperm axoneme assembly

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Apl-003836	Anas platyrhynchos	70.12	5.00e-69	253.00
IUUC-Aca-004890	Anolis carolinensis	50.33	1.00e-174	606.00
IUUC-Ame-011811	Astyanax mexicanus	50.47	3.00e-155	541.00
IUUC-Cfa-020939	Canis familiaris	92.00	1.00e-81	295.00
IUUC-Cpo-022422	Cavia porcellus	81.42	3.00e-136	477.00
IUUC-Cre-022910	Chlamydomonas reinhardtii	28.79	2.00e-50	193.00
IUUC-Cho-024331	Choloepus hoffmanni	82.34	0.00e+00	926.00
IUUC-Cin-025207	Ciona intestinalis	48.60	7.00e-175	607.00
IUUC-Csv-026299	Ciona savignyi	45.03	3.00e-130	458.00
IUUC-Dre-028682	Danio rerio	48.43	5.00e-173	600.00
IUUC-Dor-030289	Dipodomys ordii	80.05	0.00e+00	643.00
IUUC-Ete-032579	Echinops telfairi	73.69	0.00e+00	946.00
IUUC-Eca-033907	Equus caballus	81.08	0.00e+00	931.00
IUUC-Eeu-034723	Erinaceus europaeus	71.02	0.00e+00	822.00
IUUC-Fca-036062	Felis catus	83.51	0.00e+00	899.00
IUUC-Fal-036929	Ficedula albicollis	57.01	1.00e-103	369.00
IUUC-Gmo-039703	Gadus morhua	41.19	1.00e-83	303.00
IUUC-Gga-040394	Gallus gallus	56.06	0.00e+00	656.00
IUUC-Gac-041652	Gasterosteus aculeatus	40.97	4.00e-115	408.00
IUUC-Hsa-046165	Homo sapiens	96.20	0.00e+00	1157.00
IUUC-Lch-049436	Latimeria chalumnae	55.28	0.00e+00	702.00
IUUC-Loc-052062	Lepisosteus oculatus	58.44	8.00e-114	403.00
IUUC-Meu-056457	Macropus eugenii	51.69	2.00e-136	479.00
IUUC-Mmu-063303	Mus musculus	74.84	0.00e+00	962.00
IUUC-Mpu-066714	Mustela putorius furo	90.37	3.00e-119	420.00
IUUC-Nle-069920	Nomascus leucogenys	96.79	6.00e-128	449.00
IUUC-Opr-070273	Ochotona princeps	70.79	0.00e+00	899.00
IUUC-Ont-072313	Oreochromis niloticus	41.34	6.00e-124	437.00
IUUC-Ptr-091332	Pan troglodytes	96.20	0.00e+00	1159.00
IUUC-Psi-093988	Pelodiscus sinensis	63.37	2.00e-109	388.00
IUUC-Pma-094595	Petromyzon marinus	47.96	9.00e-174	603.00
IUUC-Ppa-095608	Physcomitrella patens	40.11	4.00e-111	395.00
IUUC-Pfo-097048	Poecilia formosa	42.99	1.00e-75	276.00
IUUC-Pab-097856	Pongo abelii	88.91	0.00e+00	1041.00
IUUC-Pca-100171	Procavia capensis	74.60	0.00e+00	702.00
IUUC-Pva-103088	Pteropus vampyrus	78.92	0.00e+00	930.00
IUUC-Rno-105955	Rattus norvegicus	79.85	7.00e-137	479.00
IUUC-Smo-108997	Selaginella moellendorffii	39.02	3.00e-107	382.00
IUUC-Sar-113008	Sorex araneus	67.19	0.00e+00	780.00
IUUC-Tgu-116809	Taeniopygia guttata	66.46	2.00e-65	240.00
IUUC-Tsy-119183	Tarsius syrichta	89.78	1.00e-148	519.00
IUUC-Tbe-127666	Tupaia belangeri	65.45	0.00e+00	763.00
IUUC-Ttr-128610	Tursiops truncatus	74.75	8.00e-147	513.00
IUUC-Vpa-130702	Vicugna pacos	81.03	0.00e+00	884.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence