iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Eca-034147

UUCD1 version

UUC-EqC-01037

Ensembl Protein ID

ENSECAP00000015887.1

UniProt Accession

F7CHY0; F7CHY0_HORSE

Protein Name

Uncharacterized protein

Gene Name

USP43

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSECAG00000018340.1	ENSECAT00000019412.1	ENSECAP00000015887.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	2.70e-93	313.0	100	709

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefsgyeq 89
           +GlkN+gNtC+mN+v+QcLsn+  l+e+l     ++ +        +e++++l+ l+++lw+++ +     e+++a++k+ ++f+g++q
   Q: 100  QGLKNHGNTCFMNAVVQCLSNTDLLAEFLALGRYRAAPG------RAEVTEQLAALVRALWTREYTPQLSAEFKNAVSKYGSQFQGNSQ 182
           6****************************9955555555......479***************************************** PP
   S: 90   qDaqEflaflldqleeelkkeknkpkeeeeeedkselsde..aeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslpv 176
           +Da Efl +lld+++e+l+ +++ p +e+ + + s++s++  ++  + + ++s+++  Fq q++s+++c++c+++s++++pfl +slp+
   Q: 183  HDALEFLLWLLDRVHEDLEGSSRGPGSEKLQPEASKTSENllSPPAQLSLGQSFVQSHFQAQYRSSLTCPHCRKQSNTFDPFLCVSLPI 271
           ******************9988888888888887777777778899999999************************************* PP
   S: 177  pgkeetkke................................................................................ 185
           p ++++ ++                                                                                
   Q: 272  PLRQTRFLSvtlvflsksqrflrvglavpilstvaalrkmvaeeggvpvdevilvelhpsglqrsffdeedlntiaegdsiyafqappp 360
           ****98888******************************************************************************** PP
   S: 186  ......................................................................................... 185
                                                                                                    
   Q: 361  tsrelllarppglsvsphlaaregqraslpahgenkvlllfcnvvgsglqasrfgppflmredrtiswvqlqqcilskvrylmkseapi 449
           ***************************************************************************************** PP
   S: 186  ......................................................................................... 185
                                                                                                    
   Q: 450  qnpgsmfsirvvglslacsylsaqdgrplchwavdralhlrrpggpphvklavewdsgakerlfgslqeervqdadsvwqqqqahqqhs 538
           ***************************************************************************************** PP
   S: 186  .slqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefple.Ldlspfctspeekq 272
            +l++c++ +tkee+l +++++ c++ck++q+   kl+l++lP++Li+hLkRf   + +++r+k+++ vefpl+ Ld++p++++++++ 
   Q: 539  cTLDECFQFYTKEEQLAQDDAWRCPHCKALQQGMVKLSLWTLPDILIIHLKRF--CQVGERRNKLSTLVEFPLSgLDMAPHVAQRSTSP 625
           *****************************************************..88899***********************988777 PP
   S: 273  ke....................kkkYeLiavvvHsGslssGHYvayvkn.ekgkWllfdDskVtevkeeevleetgstaYvlfYkrr 338
           k                     +  Y+L+av++H+Gsl++GHY+ay++n  +g+W+ +dDs+V++++e+ev++   + aY+lfY++r
   Q: 626  KPepgpwpswrqpaclptsyplDFLYDLYAVCNHHGSLQGGHYTAYCRNsLDGQWYSYDDSTVEPLPEDEVNT---RGAYILFYQKR 709
           66999999999**********9***************************55788*******************...********985 PP

Organism

Equus caballus

Protein Sequence
(Fasta)

GPGGAAGEGL PAPGPRRRRS LRRLFSRFLL ALGSRSRPGD SPPRPQPQPQ PGHCDGDGEG 60
GFTCAPGPAP AAPGSPGEER PPRSQTQLPA GDGARPPGAQ GLKNHGNTCF MNAVVQCLSN 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGGCCCGGGG GCGCGGCAGG AGAGGGGCTT CCCGCGCCCG GGCCCCGCCG GCGCCGCTCC 60
CTGCGCCGCC TGTTCAGCCG CTTCCTGCTG GCGCTGGGCA GCCGCTCCCG CCCCGGGGAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0005634--C:nucleus
GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001922	Ailuropoda melanoleuca	81.49	0.00e+00	1295.00
IUUC-Aca-004436	Anolis carolinensis	61.34	0.00e+00	775.00
IUUC-Ame-011153	Astyanax mexicanus	59.07	0.00e+00	865.00
IUUC-Bta-013560	Bos taurus	86.40	0.00e+00	1479.00
IUUC-Cja-018737	Callithrix jacchus	83.52	0.00e+00	1435.00
IUUC-Cfa-020347	Canis familiaris	83.51	0.00e+00	1353.00
IUUC-Csa-023656	Chlorocebus sabaeus	85.35	0.00e+00	1459.00
IUUC-Cho-024864	Choloepus hoffmanni	70.55	0.00e+00	881.00
IUUC-Dre-028066	Danio rerio	58.44	0.00e+00	868.00
IUUC-Dno-028855	Dasypus novemcinctus	78.98	0.00e+00	1308.00
IUUC-Dor-030475	Dipodomys ordii	85.75	0.00e+00	699.00
IUUC-Dme-032088	Drosophila melanogaster	37.84	3.00e-113	403.00
IUUC-Eeu-034703	Erinaceus europaeus	72.34	1.00e-138	488.00
IUUC-Fca-036550	Felis catus	79.26	0.00e+00	1124.00
IUUC-Gac-042087	Gasterosteus aculeatus	60.96	0.00e+00	859.00
IUUC-Ggo-045171	Gorilla gorilla	85.90	0.00e+00	1470.00
IUUC-Hsa-045961	Homo sapiens	85.84	0.00e+00	1472.00
IUUC-Loc-052852	Lepisosteus oculatus	62.50	0.00e+00	916.00
IUUC-Laf-054033	Loxodonta africana	82.02	0.00e+00	1335.00
IUUC-Mcc-055431	Macaca mulatta	85.13	0.00e+00	1456.00
IUUC-Mmr-061035	Microcebus murinus	86.14	0.00e+00	1395.00
IUUC-Mdo-062172	Monodelphis domestica	66.16	0.00e+00	943.00
IUUC-Mmu-063966	Mus musculus	81.15	0.00e+00	1344.00
IUUC-Mpu-066307	Mustela putorius furo	82.75	0.00e+00	1288.00
IUUC-Nle-070172	Nomascus leucogenys	85.06	0.00e+00	1469.00
IUUC-Opr-070499	Ochotona princeps	85.56	0.00e+00	1061.00
IUUC-Ont-071920	Oreochromis niloticus	61.60	0.00e+00	888.00
IUUC-Ocu-074014	Oryctolagus cuniculus	81.56	0.00e+00	1184.00
IUUC-Ola-086360	Oryzias latipes	60.73	0.00e+00	893.00
IUUC-Oga-088202	Otolemur garnettii	82.26	0.00e+00	1396.00
IUUC-Oar-089819	Ovis aries	84.86	0.00e+00	1381.00
IUUC-Ptr-091076	Pan troglodytes	85.84	0.00e+00	1475.00
IUUC-Pan-092248	Papio anubis	85.01	0.00e+00	1450.00
IUUC-Pfo-096534	Poecilia formosa	59.83	0.00e+00	816.00
IUUC-Pab-098453	Pongo abelii	82.92	0.00e+00	1403.00
IUUC-Pca-100290	Procavia capensis	66.48	0.00e+00	627.00
IUUC-Pva-102317	Pteropus vampyrus	79.63	0.00e+00	1313.00
IUUC-Rno-104948	Rattus norvegicus	79.86	0.00e+00	1242.00
IUUC-Sha-106558	Sarcophilus harrisii	65.50	0.00e+00	1048.00
IUUC-Sar-113105	Sorex araneus	68.22	0.00e+00	994.00
IUUC-Ssc-115312	Sus scrofa	86.81	0.00e+00	1453.00
IUUC-Tru-117995	Takifugu rubripes	61.93	0.00e+00	894.00
IUUC-Tsy-119325	Tarsius syrichta	73.02	0.00e+00	720.00
IUUC-Tni-120517	Tetraodon nigroviridis	58.89	0.00e+00	852.00
IUUC-Tbe-127439	Tupaia belangeri	75.00	4.00e-100	359.00
IUUC-Ttr-128829	Tursiops truncatus	77.46	0.00e+00	1288.00
IUUC-Vpa-130306	Vicugna pacos	80.60	0.00e+00	630.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence