iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Dre-027955

Ensembl Protein ID

ENSDARP00000142408.1

UniProt Accession

A0A140LGM9; A0A140LGM9_DANRE

Genbank Protein ID

ENSDARP00000142408

Protein Name

Si:ch73-223f5.2

Genbank Nucleotide ID

FP236789

Gene Name

si:ch73-223f5.2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSDARG00000105493.1	ENSDART00000172751.1	ENSDARP00000142408.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	4.80e-48	165.0	257	591

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 2    GlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelw...kskkkavsprellkalkkeaeefsgy 87
           Gl NlgNtCYmNSvLQcL++ip+++++++   ++++ +     ++  ll+ + +lf + +   +++ k+   r+++  ++++++ f+g 
   Q: 257  GLPNLGNTCYMNSVLQCLLSIPPFQHDVFL--SQEVWR-----DEDMLLSVFSDLFISRLdnsSTNLKKRLLRKVKCYIENASKVFTGD 338
           9*************************9999..555543.....4579*********99986555566677778888889999999**** PP
   S: 88   eqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslpv 176
            qqDa+Efl+  l+ l+ee +                        k  + + +  + +++++l+++ +c +c+ +++ +e+ +++sl +
   Q: 339  FQQDAHEFLMLSLSCLKEEGQ----------------------MLKMSSPTYTCPVANMEFKLETERTCVSCGLQKTFTEDANYISLVL 405
           *******************92......................3455666777888999****************************** PP
   S: 177  pgkeetkkeslqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdlspfc 265
            ++      s++d+L++++++ +++    + c +c++ + a+ + ++ ++P+vL+l  +Rf +     s+ k+ +++ + +eL+ls++ 
   Q: 406  GQNA-----SVSDSLQQYMSPSSVD----CMCCNCNGTK-ASVTQRFYSFPRVLVLLVSRFDM----LSDCKLRNRLRITEELTLSSVK 480
           ****.....9**************9....79****9866.99999****************55....55679**************888 PP
   S: 266  ts.........peekqke.................................kkkYeLiavvvHsG.slssGHYvayvknekgk.Wllfd 310
            +         +     +                                 +++Y+L++ v+H G +l sGHY++++++ +++ Wl+++
   Q: 481  GEireqpesdnQ-----RpascqsflkrilktktkvapqipndkqeepadtRVEYRLTGAVSHLGsKLFSGHYISHIRDPSDDgWLRCS 564
           775555555550.....1555555555555555555556666666667777****************************76666***** PP
   S: 311  DskVtevkeeevleetgstaYvlfYkr 337
           D +V++++++e  ee +++ Y+lfY +
   Q: 565  DFSVRKISWTEASEEIKRNCYMLFYIK 591
           **************999********87 PP

Organism

Danio rerio

Protein Sequence
(Fasta)

MDRDIQQAEK MALKSKEEIK KRMRVMFPSS SVDLEDSSFS GPGDNGKLPS PSSRKRRFPS 60
MRRVFGKILS ILMPCVCLSS EEEDSSFVSD RKTDASFSAA VHRSSEGHPE NDLPAGQQKE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGATCGTG ACATTCAGCA AGCAGAGAAA ATGGCTTTGA AGAGCAAAGA GGAGATCAAG 60
AAAAGGATGA GGGTGATGTT TCCGTCTTCT TCGGTAGATC TGGAGGATTC GTCCTTTTCA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Cel-018706	Caenorhabditis elegans	25.34	4.00e-23	103.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence